Result of FASTA (omim) for
pF1KB7740
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7740, 482 aa
1>>>pF1KB7740 482 - 482 aa - 482 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7107+/-0.000433; mu= 17.6295+/- 0.027
mean_var=103.4260+/-20.850, 0's: 0 Z-trim(113.4): 412 B-trim: 377 in 1/53
Lambda= 0.126113
statistics sampled from 22326 (22744) to 22326 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.267), width: 16
Scan time: 9.370
The best scores are: opt bits E(85289)
NP_001193921 (OMIM: 603826,617049) bile acid recep ( 482) 3269 605.7 9.1e-173
NP_001193922 (OMIM: 603826,617049) bile acid recep ( 486) 3251 602.4 8.9e-172
NP_005114 (OMIM: 603826,617049) bile acid receptor ( 472) 3009 558.4 1.6e-158
XP_011537342 (OMIM: 603826,617049) PREDICTED: bile ( 476) 2991 555.1 1.5e-157
NP_001193908 (OMIM: 603826,617049) bile acid recep ( 476) 2991 555.1 1.5e-157
NP_001193906 (OMIM: 603826,617049) bile acid recep ( 476) 2991 555.1 1.5e-157
NP_001193907 (OMIM: 603826,617049) bile acid recep ( 425) 1810 340.2 6.8e-93
XP_011537343 (OMIM: 603826,617049) PREDICTED: bile ( 435) 1810 340.2 6.9e-93
XP_011537344 (OMIM: 603826,617049) PREDICTED: bile ( 280) 1762 331.3 2.1e-90
XP_006719782 (OMIM: 603826,617049) PREDICTED: bile ( 284) 1744 328.0 2.1e-89
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453) 924 179.0 2.4e-44
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453) 924 179.0 2.4e-44
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols ( 402) 915 177.3 6.8e-44
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols ( 402) 915 177.3 6.8e-44
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols ( 402) 915 177.3 6.8e-44
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols ( 402) 915 177.3 6.8e-44
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402) 915 177.3 6.8e-44
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols ( 402) 915 177.3 6.8e-44
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols ( 447) 915 177.4 7.3e-44
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols ( 447) 915 177.4 7.3e-44
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols ( 447) 915 177.4 7.3e-44
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols ( 447) 915 177.4 7.3e-44
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols ( 447) 915 177.4 7.3e-44
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447) 915 177.4 7.3e-44
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols ( 447) 915 177.4 7.3e-44
XP_016872545 (OMIM: 602423) PREDICTED: oxysterols ( 332) 721 142.0 2.5e-33
XP_016872546 (OMIM: 602423) PREDICTED: oxysterols ( 323) 714 140.7 5.9e-33
NP_148934 (OMIM: 603065) nuclear receptor subfamil ( 397) 571 114.7 4.7e-25
NP_955366 (OMIM: 190120,614450) thyroid hormone re ( 410) 560 112.8 1.9e-24
XP_016862602 (OMIM: 145650,188570,190160,274300) P ( 430) 557 112.2 2.9e-24
XP_016862603 (OMIM: 145650,188570,190160,274300) P ( 430) 557 112.2 2.9e-24
XP_011532355 (OMIM: 145650,188570,190160,274300) P ( 430) 557 112.2 2.9e-24
XP_016862604 (OMIM: 145650,188570,190160,274300) P ( 430) 557 112.2 2.9e-24
XP_011532349 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_016862600 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_005265481 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_011532351 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_011532350 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_005265480 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_006713380 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
NP_001239563 (OMIM: 145650,188570,190160,274300) t ( 461) 557 112.3 3e-24
XP_016862597 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_016862601 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_011532354 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_011532352 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_011532348 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
XP_006713381 (OMIM: 145650,188570,190160,274300) P ( 461) 557 112.3 3e-24
NP_000452 (OMIM: 145650,188570,190160,274300) thyr ( 461) 557 112.3 3e-24
NP_001121648 (OMIM: 145650,188570,190160,274300) t ( 461) 557 112.3 3e-24
NP_001121649 (OMIM: 145650,188570,190160,274300) t ( 461) 557 112.3 3e-24
>>NP_001193921 (OMIM: 603826,617049) bile acid receptor (482 aa)
initn: 3269 init1: 3269 opt: 3269 Z-score: 3222.7 bits: 605.7 E(85289): 9.1e-173
Smith-Waterman score: 3269; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)
10 20 30 40 50 60
pF1KB7 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 MDMYMRRKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDMYMRRKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 QVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 RIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 LLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWD
430 440 450 460 470 480
pF1KB7 VQ
::
NP_001 VQ
>>NP_001193922 (OMIM: 603826,617049) bile acid receptor (486 aa)
initn: 3320 init1: 1810 opt: 3251 Z-score: 3204.9 bits: 602.4 E(85289): 8.9e-172
Smith-Waterman score: 3251; 99.2% identity (99.2% similar) in 486 aa overlap (1-482:1-486)
10 20 30 40 50 60
pF1KB7 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
130 140 150 160 170 180
190 200 210 220 230
pF1KB7 MDMYMRRKCQECRLRKCKEMGMLAEC----LLTEIQCKSKRLRKNVKQHADQTVNEDSEG
:::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_001 MDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 RDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 LTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 LLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEK
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 LQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLC
430 440 450 460 470 480
480
pF1KB7 EIWDVQ
::::::
NP_001 EIWDVQ
>>NP_005114 (OMIM: 603826,617049) bile acid receptor iso (472 aa)
initn: 3009 init1: 3009 opt: 3009 Z-score: 2967.1 bits: 558.4 E(85289): 1.6e-158
Smith-Waterman score: 3009; 100.0% identity (100.0% similar) in 446 aa overlap (37-482:27-472)
10 20 30 40 50 60
pF1KB7 GLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
::::::::::::::::::::::::::::::
NP_005 MGSKMNLIEHSHLPTTDEFSFSENLFGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 RKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQVTSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQVTSTT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 KSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 VLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSG
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 ISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 KLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
420 430 440 450 460 470
>>XP_011537342 (OMIM: 603826,617049) PREDICTED: bile aci (476 aa)
initn: 3060 init1: 1810 opt: 2991 Z-score: 2949.4 bits: 555.1 E(85289): 1.5e-157
Smith-Waterman score: 2991; 99.1% identity (99.1% similar) in 450 aa overlap (37-482:27-476)
10 20 30 40 50 60
pF1KB7 GLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
::::::::::::::::::::::::::::::
XP_011 MGSKMNLIEHSHLPTTDEFSFSENLFGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 RKCQECRLRKCKEMGMLAEC----LLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQV
:::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_011 RKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 TSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMAT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 NHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERI
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 RNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 DVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
420 430 440 450 460 470
>>NP_001193908 (OMIM: 603826,617049) bile acid receptor (476 aa)
initn: 3060 init1: 1810 opt: 2991 Z-score: 2949.4 bits: 555.1 E(85289): 1.5e-157
Smith-Waterman score: 2991; 99.1% identity (99.1% similar) in 450 aa overlap (37-482:27-476)
10 20 30 40 50 60
pF1KB7 GLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
::::::::::::::::::::::::::::::
NP_001 MGSKMNLIEHSHLPTTDEFSFSENLFGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 RKCQECRLRKCKEMGMLAEC----LLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQV
:::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 RKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 TSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMAT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 NHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERI
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 RNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 DVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
420 430 440 450 460 470
>>NP_001193906 (OMIM: 603826,617049) bile acid receptor (476 aa)
initn: 3060 init1: 1810 opt: 2991 Z-score: 2949.4 bits: 555.1 E(85289): 1.5e-157
Smith-Waterman score: 2991; 99.1% identity (99.1% similar) in 450 aa overlap (37-482:27-476)
10 20 30 40 50 60
pF1KB7 GLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
::::::::::::::::::::::::::::::
NP_001 MGSKMNLIEHSHLPTTDEFSFSENLFGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 RKCQECRLRKCKEMGMLAEC----LLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQV
:::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 RKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 TSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMAT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 NHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERI
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 RNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 DVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
420 430 440 450 460 470
>>NP_001193907 (OMIM: 603826,617049) bile acid receptor (425 aa)
initn: 1810 init1: 1810 opt: 1810 Z-score: 1788.8 bits: 340.2 E(85289): 6.8e-93
Smith-Waterman score: 2559; 89.5% identity (89.5% similar) in 446 aa overlap (37-482:27-425)
10 20 30 40 50 60
pF1KB7 GLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
::::::::::::::::::::::::::::::
NP_001 MGSKMNLIEHSHLPTTDEFSFSENLFGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMR
:::::::::::::::::::::::::::::::::
NP_001 SAGRIKGDELCVVCGDRASGYHYNALTCEGCKG---------------------------
120 130 140
190 200 210 220 230 240
pF1KB7 RKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQVTSTT
::::::::::::::::::::::::::::::::::::::::
NP_001 --------------------LLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQVTSTT
150 160 170 180
250 260 270 280 290 300
pF1KB7 KSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQ
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB7 VLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSG
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB7 ISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQ
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB7 KLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
370 380 390 400 410 420
>>XP_011537343 (OMIM: 603826,617049) PREDICTED: bile aci (435 aa)
initn: 1810 init1: 1810 opt: 1810 Z-score: 1788.6 bits: 340.2 E(85289): 6.9e-93
Smith-Waterman score: 2819; 90.2% identity (90.2% similar) in 482 aa overlap (1-482:1-435)
10 20 30 40 50 60
pF1KB7 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
:::::::::::::::::::::::::::::::::::::::
XP_011 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKG---------------------
130 140 150
190 200 210 220 230 240
pF1KB7 MDMYMRRKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLR
::::::::::::::::::::::::::::::::::
XP_011 --------------------------LLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLR
160 170 180 190
250 260 270 280 290 300
pF1KB7 QVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEM
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB7 ATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEE
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB7 RIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEP
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB7 LLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWD
380 390 400 410 420 430
pF1KB7 VQ
::
XP_011 VQ
>>XP_011537344 (OMIM: 603826,617049) PREDICTED: bile aci (280 aa)
initn: 1836 init1: 1752 opt: 1762 Z-score: 1743.9 bits: 331.3 E(85289): 2.1e-90
Smith-Waterman score: 1762; 95.1% identity (97.4% similar) in 267 aa overlap (1-267:1-267)
10 20 30 40 50 60
pF1KB7 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 MDMYMRRKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDMYMRRKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 QVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEM
:::::::::: . .:. : . : .:.
XP_011 QVTSTTKSCRCRRKLNSPQINRLFYILLWIHITNRGCLRK
250 260 270 280
>>XP_006719782 (OMIM: 603826,617049) PREDICTED: bile aci (284 aa)
initn: 1803 init1: 1466 opt: 1744 Z-score: 1726.1 bits: 328.0 E(85289): 2.1e-89
Smith-Waterman score: 1744; 93.7% identity (95.9% similar) in 271 aa overlap (1-267:1-271)
10 20 30 40 50 60
pF1KB7 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
130 140 150 160 170 180
190 200 210 220 230
pF1KB7 MDMYMRRKCQECRLRKCKEMGMLAEC----LLTEIQCKSKRLRKNVKQHADQTVNEDSEG
:::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_006 MDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 RDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLI
:::::::::::::: . .:. : . : .:.
XP_006 RDLRQVTSTTKSCRCRRKLNSPQINRLFYILLWIHITNRGCLRK
250 260 270 280
300 310 320 330 340 350
pF1KB7 LTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSD
482 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:19:08 2016 done: Fri Nov 4 09:19:09 2016
Total Scan time: 9.370 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]