FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7749, 443 aa 1>>>pF1KB7749 443 - 443 aa - 443 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.8255+/-0.000471; mu= -28.3369+/- 0.030 mean_var=766.4970+/-153.670, 0's: 0 Z-trim(126.2): 103 B-trim: 0 in 0/59 Lambda= 0.046325 statistics sampled from 51485 (51624) to 51485 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.84), E-opt: 0.2 (0.605), width: 16 Scan time: 6.890 The best scores are: opt bits E(85289) XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 3151 225.2 2.7e-58 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 3151 225.2 2.7e-58 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 3151 225.2 2.7e-58 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 3151 225.2 2.7e-58 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 3151 225.2 2.7e-58 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 3151 225.2 2.7e-58 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 3151 225.2 2.7e-58 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 959 78.7 3.4e-14 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 959 78.7 3.4e-14 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 959 78.7 3.4e-14 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 959 78.7 3.4e-14 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 959 78.7 3.4e-14 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 959 78.7 3.4e-14 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 956 78.5 3.9e-14 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 883 73.6 1.1e-12 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 883 73.6 1.1e-12 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 883 73.6 1.1e-12 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 883 73.6 1.1e-12 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 883 73.6 1.1e-12 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 883 73.6 1.1e-12 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 883 73.6 1.1e-12 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 883 73.6 1.1e-12 XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 854 71.8 5.4e-12 XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 854 71.8 5.4e-12 XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 854 71.8 5.4e-12 XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 854 71.8 5.4e-12 XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 854 71.8 5.4e-12 XP_016880050 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 854 71.8 5.4e-12 XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 854 71.8 5.4e-12 XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 854 71.8 5.4e-12 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 746 64.4 5.7e-10 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 746 64.4 5.7e-10 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 710 61.9 2.6e-09 XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 710 62.1 3.8e-09 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 463 45.4 0.00024 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 444 44.2 0.00068 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 432 43.2 0.00091 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 403 41.4 0.0042 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 394 40.9 0.0071 >>XP_005249788 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 3151 init1: 3151 opt: 3151 Z-score: 1167.5 bits: 225.2 E(85289): 2.7e-58 Smith-Waterman score: 3151; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB7 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT 370 380 390 400 410 420 430 440 pF1KB7 YTDLTGHHPSQGRIQEAPKLTHL ::::::::::::::::::::::: XP_005 YTDLTGHHPSQGRIQEAPKLTHL 430 440 >>XP_005249789 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 3151 init1: 3151 opt: 3151 Z-score: 1167.5 bits: 225.2 E(85289): 2.7e-58 Smith-Waterman score: 3151; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB7 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT 370 380 390 400 410 420 430 440 pF1KB7 YTDLTGHHPSQGRIQEAPKLTHL ::::::::::::::::::::::: XP_005 YTDLTGHHPSQGRIQEAPKLTHL 430 440 >>XP_005249787 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 3151 init1: 3151 opt: 3151 Z-score: 1167.5 bits: 225.2 E(85289): 2.7e-58 Smith-Waterman score: 3151; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB7 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT 370 380 390 400 410 420 430 440 pF1KB7 YTDLTGHHPSQGRIQEAPKLTHL ::::::::::::::::::::::: XP_005 YTDLTGHHPSQGRIQEAPKLTHL 430 440 >>XP_006715778 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 3151 init1: 3151 opt: 3151 Z-score: 1167.5 bits: 225.2 E(85289): 2.7e-58 Smith-Waterman score: 3151; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB7 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT 370 380 390 400 410 420 430 440 pF1KB7 YTDLTGHHPSQGRIQEAPKLTHL ::::::::::::::::::::::: XP_006 YTDLTGHHPSQGRIQEAPKLTHL 430 440 >>XP_011513645 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 3151 init1: 3151 opt: 3151 Z-score: 1167.5 bits: 225.2 E(85289): 2.7e-58 Smith-Waterman score: 3151; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB7 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT 370 380 390 400 410 420 430 440 pF1KB7 YTDLTGHHPSQGRIQEAPKLTHL ::::::::::::::::::::::: XP_011 YTDLTGHHPSQGRIQEAPKLTHL 430 440 >>NP_109377 (OMIM: 142954) homeobox protein Hox-A3 isofo (443 aa) initn: 3151 init1: 3151 opt: 3151 Z-score: 1167.5 bits: 225.2 E(85289): 2.7e-58 Smith-Waterman score: 3151; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB7 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT 370 380 390 400 410 420 430 440 pF1KB7 YTDLTGHHPSQGRIQEAPKLTHL ::::::::::::::::::::::: NP_109 YTDLTGHHPSQGRIQEAPKLTHL 430 440 >>NP_705895 (OMIM: 142954) homeobox protein Hox-A3 isofo (443 aa) initn: 3151 init1: 3151 opt: 3151 Z-score: 1167.5 bits: 225.2 E(85289): 2.7e-58 Smith-Waterman score: 3151; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB7 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT 370 380 390 400 410 420 430 440 pF1KB7 YTDLTGHHPSQGRIQEAPKLTHL ::::::::::::::::::::::: NP_705 YTDLTGHHPSQGRIQEAPKLTHL 430 440 >>XP_011523022 (OMIM: 142966) PREDICTED: homeobox protei (431 aa) initn: 831 init1: 605 opt: 959 Z-score: 375.9 bits: 78.7 E(85289): 3.4e-14 Smith-Waterman score: 1415; 50.4% identity (70.6% similar) in 476 aa overlap (1-443:1-431) 10 20 30 40 50 pF1KB7 MQKATYYDSSA--IYGGYP-YQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSS ::::::::..: ..::: : ..:::.... :: : .:: .:.:.: :::::: .. XP_011 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQP-PFQAATHLEGDYQRSACSLQSLGN 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 AGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPA :. : :..::. .:.: :.:. : : .:::. ::. :: . . . XP_011 AAPHAKSKELNGSCMR---------PGLA------PEPLSAPPGSPPPSAAPTSATSNSS 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 APPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGE ::...::. . : :: :..::::::::::::..: :..: ...: XP_011 NGGGPSKSGPPKCG------------PGTNS-TLTKQIFPWMKESRQTSKLKNNSPGTAE 110 120 130 140 150 180 190 200 210 pF1KB7 SCAG-----------------------DKSPPGQASSKRARTAYTSAQLVELEKEFHFNR .:.: ::::::.:.:::::::::::::::::::::::: XP_011 GCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNR 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB7 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPP--G ::::::::::::::::.::::::::::::::::::::.::. .:::: ::. :: : . XP_011 YLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQS 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB7 AGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAA ..:..:..::.. : :: ::: :.: :..:.:: ..: : .:. : ..: . XP_011 TAGFMNALHSMTPS--YESPSPPAFGKAHQNAYALP-SNYQPPLKGCGAP----QKYPPT 280 290 300 310 320 340 350 360 370 380 pF1KB7 GAGAGGTPDYDPHAHGLQGNG-SYGTPHIQGSPVFVGGS-YVEPMSN-SGPALFGLTHLP : :.:.::. ::.:: .:::: .:::::.:::. :..:. .::.:.::.:: XP_011 PA-----PEYEPHV--LQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLS 330 340 350 360 370 390 400 410 420 430 440 pF1KB7 HAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHH--PSQGRIQEAPKLTHL : :: .::.:: :.. ..:::: :::::::::..:: : ::::::::::::: XP_011 HHPSGNLDYNGAPPMAPSQHHGPC--EPHPTYTDLSSHHAPPPQGRIQEAPKLTHL 380 390 400 410 420 430 >>XP_005257334 (OMIM: 142966) PREDICTED: homeobox protei (431 aa) initn: 831 init1: 605 opt: 959 Z-score: 375.9 bits: 78.7 E(85289): 3.4e-14 Smith-Waterman score: 1415; 50.4% identity (70.6% similar) in 476 aa overlap (1-443:1-431) 10 20 30 40 50 pF1KB7 MQKATYYDSSA--IYGGYP-YQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSS ::::::::..: ..::: : ..:::.... :: : .:: .:.:.: :::::: .. XP_005 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQP-PFQAATHLEGDYQRSACSLQSLGN 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 AGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPA :. : :..::. .:.: :.:. : : .:::. ::. :: . . . XP_005 AAPHAKSKELNGSCMR---------PGLA------PEPLSAPPGSPPPSAAPTSATSNSS 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 APPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGE ::...::. . : :: :..::::::::::::..: :..: ...: XP_005 NGGGPSKSGPPKCG------------PGTNS-TLTKQIFPWMKESRQTSKLKNNSPGTAE 110 120 130 140 150 180 190 200 210 pF1KB7 SCAG-----------------------DKSPPGQASSKRARTAYTSAQLVELEKEFHFNR .:.: ::::::.:.:::::::::::::::::::::::: XP_005 GCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNR 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB7 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPP--G ::::::::::::::::.::::::::::::::::::::.::. .:::: ::. :: : . XP_005 YLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQS 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB7 AGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAA ..:..:..::.. : :: ::: :.: :..:.:: ..: : .:. : ..: . XP_005 TAGFMNALHSMTPS--YESPSPPAFGKAHQNAYALP-SNYQPPLKGCGAP----QKYPPT 280 290 300 310 320 340 350 360 370 380 pF1KB7 GAGAGGTPDYDPHAHGLQGNG-SYGTPHIQGSPVFVGGS-YVEPMSN-SGPALFGLTHLP : :.:.::. ::.:: .:::: .:::::.:::. :..:. .::.:.::.:: XP_005 PA-----PEYEPHV--LQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLS 330 340 350 360 370 390 400 410 420 430 440 pF1KB7 HAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHH--PSQGRIQEAPKLTHL : :: .::.:: :.. ..:::: :::::::::..:: : ::::::::::::: XP_005 HHPSGNLDYNGAPPMAPSQHHGPC--EPHPTYTDLSSHHAPPPQGRIQEAPKLTHL 380 390 400 410 420 430 >>NP_002137 (OMIM: 142966) homeobox protein Hox-B3 isofo (431 aa) initn: 831 init1: 605 opt: 959 Z-score: 375.9 bits: 78.7 E(85289): 3.4e-14 Smith-Waterman score: 1415; 50.4% identity (70.6% similar) in 476 aa overlap (1-443:1-431) 10 20 30 40 50 pF1KB7 MQKATYYDSSA--IYGGYP-YQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSS ::::::::..: ..::: : ..:::.... :: : .:: .:.:.: :::::: .. NP_002 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQP-PFQAATHLEGDYQRSACSLQSLGN 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 AGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPA :. : :..::. .:.: :.:. : : .:::. ::. :: . . . NP_002 AAPHAKSKELNGSCMR---------PGLA------PEPLSAPPGSPPPSAAPTSATSNSS 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 APPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGE ::...::. . : :: :..::::::::::::..: :..: ...: NP_002 NGGGPSKSGPPKCG------------PGTNS-TLTKQIFPWMKESRQTSKLKNNSPGTAE 110 120 130 140 150 180 190 200 210 pF1KB7 SCAG-----------------------DKSPPGQASSKRARTAYTSAQLVELEKEFHFNR .:.: ::::::.:.:::::::::::::::::::::::: NP_002 GCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNR 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB7 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPP--G ::::::::::::::::.::::::::::::::::::::.::. .:::: ::. :: : . NP_002 YLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQS 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB7 AGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAA ..:..:..::.. : :: ::: :.: :..:.:: ..: : .:. : ..: . NP_002 TAGFMNALHSMTPS--YESPSPPAFGKAHQNAYALP-SNYQPPLKGCGAP----QKYPPT 280 290 300 310 320 340 350 360 370 380 pF1KB7 GAGAGGTPDYDPHAHGLQGNG-SYGTPHIQGSPVFVGGS-YVEPMSN-SGPALFGLTHLP : :.:.::. ::.:: .:::: .:::::.:::. :..:. .::.:.::.:: NP_002 PA-----PEYEPHV--LQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLS 330 340 350 360 370 390 400 410 420 430 440 pF1KB7 HAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHH--PSQGRIQEAPKLTHL : :: .::.:: :.. ..:::: :::::::::..:: : ::::::::::::: NP_002 HHPSGNLDYNGAPPMAPSQHHGPC--EPHPTYTDLSSHHAPPPQGRIQEAPKLTHL 380 390 400 410 420 430 443 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:22:50 2016 done: Fri Nov 4 09:22:51 2016 Total Scan time: 6.890 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]