FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7750, 468 aa 1>>>pF1KB7750 468 - 468 aa - 468 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6101+/-0.000327; mu= 2.8824+/- 0.021 mean_var=177.5732+/-36.093, 0's: 0 Z-trim(121.4): 138 B-trim: 0 in 0/55 Lambda= 0.096247 statistics sampled from 37719 (37868) to 37719 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.444), width: 16 Scan time: 11.300 The best scores are: opt bits E(85289) NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 3209 457.6 3.4e-128 NP_001078940 (OMIM: 602628) forkhead box protein N ( 490) 1797 261.5 3.7e-69 XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 XP_005264340 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 XP_016859446 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 XP_016859448 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 740 114.7 5e-25 XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 740 114.7 5e-25 XP_016880718 (OMIM: 600838,601705) PREDICTED: fork ( 567) 382 65.1 5.8e-10 XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 377 64.3 7.5e-10 XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 377 64.3 7.5e-10 XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 377 64.3 7.5e-10 XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 377 64.3 7.9e-10 XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 377 64.4 1e-09 XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 377 64.4 1e-09 XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 377 64.4 1e-09 NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 377 64.4 1e-09 XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 377 64.4 1e-09 XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 377 64.4 1e-09 NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 372 63.6 1.2e-09 XP_016880720 (OMIM: 600838,601705) PREDICTED: fork ( 384) 367 62.9 1.8e-09 XP_011536225 (OMIM: 609429) PREDICTED: forkhead bo ( 314) 364 62.4 2e-09 XP_016880719 (OMIM: 600838,601705) PREDICTED: fork ( 485) 367 63.0 2.2e-09 XP_016874308 (OMIM: 609429) PREDICTED: forkhead bo ( 377) 364 62.5 2.3e-09 XP_016874307 (OMIM: 609429) PREDICTED: forkhead bo ( 474) 364 62.5 2.8e-09 NP_998761 (OMIM: 609429) forkhead box protein N4 [ ( 517) 364 62.6 3e-09 XP_011536224 (OMIM: 609429) PREDICTED: forkhead bo ( 518) 364 62.6 3e-09 NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 354 61.2 8.4e-09 NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 339 59.0 2.4e-08 XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 342 59.5 2.7e-08 NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 342 59.5 2.8e-08 XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 342 59.5 2.8e-08 XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 342 59.5 2.9e-08 XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 342 59.6 2.9e-08 NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 342 59.6 2.9e-08 NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 342 59.6 2.9e-08 NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 342 59.6 2.9e-08 XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 342 59.6 3e-08 NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 324 56.9 1.1e-07 NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 328 57.6 1.2e-07 NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 320 56.4 1.6e-07 NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 321 56.6 1.8e-07 NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 318 56.1 1.9e-07 XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 321 56.6 2.1e-07 NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 321 56.7 2.5e-07 NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 315 55.7 2.6e-07 >>NP_005188 (OMIM: 602628) forkhead box protein N3 isofo (468 aa) initn: 3209 init1: 3209 opt: 3209 Z-score: 2422.6 bits: 457.6 E(85289): 3.4e-128 Smith-Waterman score: 3209; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468) 10 20 30 40 50 60 pF1KB7 MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KRNGALLQVPPGVIQNGARVLSRGLFPGVRPLPITPIGVTAAMRNGITSCRMRTESEPSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KRNGALLQVPPGVIQNGARVLSRGLFPGVRPLPITPIGVTAAMRNGITSCRMRTESEPSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYEFATKGSQEGSEGSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYEFATKGSQEGSEGSEG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRT 370 380 390 400 410 420 430 440 450 460 pF1KB7 EKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN :::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN 430 440 450 460 >>NP_001078940 (OMIM: 602628) forkhead box protein N3 is (490 aa) initn: 1808 init1: 1763 opt: 1797 Z-score: 1362.7 bits: 261.5 E(85289): 3.7e-69 Smith-Waterman score: 3149; 95.3% identity (95.3% similar) in 490 aa overlap (1-468:1-490) 10 20 30 40 50 60 pF1KB7 MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFF 190 200 210 220 230 240 250 260 270 pF1KB7 KRNGALLQ----------------------VPPGVIQNGARVLSRGLFPGVRPLPITPIG :::::::: ::::::::::::::::::::::::::::: NP_001 KRNGALLQDPDIDAASAMMLLNTPPEIQAGFPPGVIQNGARVLSRGLFPGVRPLPITPIG 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 VTAAMRNGITSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTAAMRNGITSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSS 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB7 SADDHYEFATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SADDHYEFATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKK 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 RQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKG 430 440 450 460 470 480 460 pF1KB7 QKEQKETTKN :::::::::: NP_001 QKEQKETTKN 490 >>XP_011531110 (OMIM: 143089) PREDICTED: forkhead box pr (431 aa) initn: 926 init1: 571 opt: 740 Z-score: 570.3 bits: 114.7 E(85289): 5e-25 Smith-Waterman score: 1027; 44.0% identity (63.3% similar) in 482 aa overlap (1-467:1-431) 10 20 30 40 50 pF1KB7 MGPV--MPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDE :::: : :.:. :. : .:::: : ... .:. : . : : .. :. XP_011 MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAV------DAARPKATLVDSESADD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ELTNLNWLHESKNLLKSF--GESVLRSVSPVQDLDDDTPPS--PAHSDMPYDARQNPNCK ::::::::::: ::: .: : : :::. :.. : :: :: . : ... . : XP_011 ELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNP--EKKSATSK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKK :::::: ::.:::: ::.: ::::.::.:::.::::::.:::::::::::::::::::.: XP_011 PPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIW :.. ... :::::::.::::. :::::::: : :.. . :. : : . XP_011 VERSHGKVNGKGSLWCVDPEYKPNLIQALKKQP-------FSSASS-----QNGSLSPHY 180 190 200 210 220 240 250 260 270 280 pF1KB7 PGSTFFKRNGALLQVPPGVIQNGARVL-----SRGLFPGVRPLPI-TPIGVTAAMRNGI- :. .:.: . . .: .: .:.. .:::. : . .. :.. XP_011 L-SSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFH 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 --TSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYE .. :.. ::. : ..: :::::::::... . : .: .: :: ::.:. :: XP_011 HPSAVRLQ-ESD----SLATSIDPKEDHNYSASSMAAQRCASRSS---VSSLSSVDEVYE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 FATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKA : :.:. ::.:::: :.:.:. .:.. .: : ::::::::: XP_011 FIPKNSHVGSDGSEG-FHSEED-TDVDYED---------DPLGDSGYASQ--------PC 340 350 360 370 410 420 430 440 450 460 pF1KB7 RKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKET :. :: : . : : ::.::::::::::::::.::... . ::: :. ::. XP_011 AKISEKGQSGKKMRKQTCQEID-EELKEAAGSLLHLAGIRTCLGSLIS-TAKTQN-QKQR 380 390 400 410 420 pF1KB7 TKN : XP_011 KK 430 >>XP_006712065 (OMIM: 143089) PREDICTED: forkhead box pr (431 aa) initn: 926 init1: 571 opt: 740 Z-score: 570.3 bits: 114.7 E(85289): 5e-25 Smith-Waterman score: 1027; 44.0% identity (63.3% similar) in 482 aa overlap (1-467:1-431) 10 20 30 40 50 pF1KB7 MGPV--MPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDE :::: : :.:. :. : .:::: : ... .:. : . : : .. :. XP_006 MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAV------DAARPKATLVDSESADD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ELTNLNWLHESKNLLKSF--GESVLRSVSPVQDLDDDTPPS--PAHSDMPYDARQNPNCK ::::::::::: ::: .: : : :::. :.. : :: :: . : ... . : XP_006 ELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNP--EKKSATSK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKK :::::: ::.:::: ::.: ::::.::.:::.::::::.:::::::::::::::::::.: XP_006 PPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIW :.. ... :::::::.::::. :::::::: : :.. . :. : : . XP_006 VERSHGKVNGKGSLWCVDPEYKPNLIQALKKQP-------FSSASS-----QNGSLSPHY 180 190 200 210 220 240 250 260 270 280 pF1KB7 PGSTFFKRNGALLQVPPGVIQNGARVL-----SRGLFPGVRPLPI-TPIGVTAAMRNGI- :. .:.: . . .: .: .:.. .:::. : . .. :.. XP_006 L-SSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFH 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 --TSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYE .. :.. ::. : ..: :::::::::... . : .: .: :: ::.:. :: XP_006 HPSAVRLQ-ESD----SLATSIDPKEDHNYSASSMAAQRCASRSS---VSSLSSVDEVYE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 FATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKA : :.:. ::.:::: :.:.:. .:.. .: : ::::::::: XP_006 FIPKNSHVGSDGSEG-FHSEED-TDVDYED---------DPLGDSGYASQ--------PC 340 350 360 370 410 420 430 440 450 460 pF1KB7 RKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKET :. :: : . : : ::.::::::::::::::.::... . ::: :. ::. XP_006 AKISEKGQSGKKMRKQTCQEID-EELKEAAGSLLHLAGIRTCLGSLIS-TAKTQN-QKQR 380 390 400 410 420 pF1KB7 TKN : XP_006 KK 430 >>XP_016859447 (OMIM: 143089) PREDICTED: forkhead box pr (431 aa) initn: 926 init1: 571 opt: 740 Z-score: 570.3 bits: 114.7 E(85289): 5e-25 Smith-Waterman score: 1027; 44.0% identity (63.3% similar) in 482 aa overlap (1-467:1-431) 10 20 30 40 50 pF1KB7 MGPV--MPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDE :::: : :.:. :. : .:::: : ... .:. : . : : .. :. XP_016 MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAV------DAARPKATLVDSESADD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ELTNLNWLHESKNLLKSF--GESVLRSVSPVQDLDDDTPPS--PAHSDMPYDARQNPNCK ::::::::::: ::: .: : : :::. :.. : :: :: . : ... . : XP_016 ELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNP--EKKSATSK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKK :::::: ::.:::: ::.: ::::.::.:::.::::::.:::::::::::::::::::.: XP_016 PPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIW :.. ... :::::::.::::. :::::::: : :.. . :. : : . XP_016 VERSHGKVNGKGSLWCVDPEYKPNLIQALKKQP-------FSSASS-----QNGSLSPHY 180 190 200 210 220 240 250 260 270 280 pF1KB7 PGSTFFKRNGALLQVPPGVIQNGARVL-----SRGLFPGVRPLPI-TPIGVTAAMRNGI- :. .:.: . . .: .: .:.. .:::. : . .. :.. XP_016 L-SSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFH 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 --TSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYE .. :.. ::. : ..: :::::::::... . : .: .: :: ::.:. :: XP_016 HPSAVRLQ-ESD----SLATSIDPKEDHNYSASSMAAQRCASRSS---VSSLSSVDEVYE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 FATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKA : :.:. ::.:::: :.:.:. .:.. .: : ::::::::: XP_016 FIPKNSHVGSDGSEG-FHSEED-TDVDYED---------DPLGDSGYASQ--------PC 340 350 360 370 410 420 430 440 450 460 pF1KB7 RKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKET :. :: : . : : ::.::::::::::::::.::... . ::: :. ::. XP_016 AKISEKGQSGKKMRKQTCQEID-EELKEAAGSLLHLAGIRTCLGSLIS-TAKTQN-QKQR 380 390 400 410 420 pF1KB7 TKN : XP_016 KK 430 >>XP_005264340 (OMIM: 143089) PREDICTED: forkhead box pr (431 aa) initn: 926 init1: 571 opt: 740 Z-score: 570.3 bits: 114.7 E(85289): 5e-25 Smith-Waterman score: 1027; 44.0% identity (63.3% similar) in 482 aa overlap (1-467:1-431) 10 20 30 40 50 pF1KB7 MGPV--MPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDE :::: : :.:. :. : .:::: : ... .:. : . : : .. :. XP_005 MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAV------DAARPKATLVDSESADD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ELTNLNWLHESKNLLKSF--GESVLRSVSPVQDLDDDTPPS--PAHSDMPYDARQNPNCK ::::::::::: ::: .: : : :::. :.. : :: :: . : ... . : XP_005 ELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNP--EKKSATSK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKK :::::: ::.:::: ::.: ::::.::.:::.::::::.:::::::::::::::::::.: XP_005 PPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIW :.. ... :::::::.::::. :::::::: : :.. . :. : : . XP_005 VERSHGKVNGKGSLWCVDPEYKPNLIQALKKQP-------FSSASS-----QNGSLSPHY 180 190 200 210 220 240 250 260 270 280 pF1KB7 PGSTFFKRNGALLQVPPGVIQNGARVL-----SRGLFPGVRPLPI-TPIGVTAAMRNGI- :. .:.: . . .: .: .:.. .:::. : . .. :.. XP_005 L-SSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFH 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 --TSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYE .. :.. ::. : ..: :::::::::... . : .: .: :: ::.:. :: XP_005 HPSAVRLQ-ESD----SLATSIDPKEDHNYSASSMAAQRCASRSS---VSSLSSVDEVYE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 FATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKA : :.:. ::.:::: :.:.:. .:.. .: : ::::::::: XP_005 FIPKNSHVGSDGSEG-FHSEED-TDVDYED---------DPLGDSGYASQ--------PC 340 350 360 370 410 420 430 440 450 460 pF1KB7 RKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKET :. :: : . : : ::.::::::::::::::.::... . ::: :. ::. XP_005 AKISEKGQSGKKMRKQTCQEID-EELKEAAGSLLHLAGIRTCLGSLIS-TAKTQN-QKQR 380 390 400 410 420 pF1KB7 TKN : XP_005 KK 430 >>XP_006712064 (OMIM: 143089) PREDICTED: forkhead box pr (431 aa) initn: 926 init1: 571 opt: 740 Z-score: 570.3 bits: 114.7 E(85289): 5e-25 Smith-Waterman score: 1027; 44.0% identity (63.3% similar) in 482 aa overlap (1-467:1-431) 10 20 30 40 50 pF1KB7 MGPV--MPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDE :::: : :.:. :. : .:::: : ... .:. : . : : .. :. XP_006 MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAV------DAARPKATLVDSESADD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ELTNLNWLHESKNLLKSF--GESVLRSVSPVQDLDDDTPPS--PAHSDMPYDARQNPNCK ::::::::::: ::: .: : : :::. :.. : :: :: . : ... . : XP_006 ELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNP--EKKSATSK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKK :::::: ::.:::: ::.: ::::.::.:::.::::::.:::::::::::::::::::.: XP_006 PPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIW :.. ... :::::::.::::. :::::::: : :.. . :. : : . XP_006 VERSHGKVNGKGSLWCVDPEYKPNLIQALKKQP-------FSSASS-----QNGSLSPHY 180 190 200 210 220 240 250 260 270 280 pF1KB7 PGSTFFKRNGALLQVPPGVIQNGARVL-----SRGLFPGVRPLPI-TPIGVTAAMRNGI- :. .:.: . . .: .: .:.. .:::. : . .. :.. XP_006 L-SSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFH 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 --TSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYE .. :.. ::. : ..: :::::::::... . : .: .: :: ::.:. :: XP_006 HPSAVRLQ-ESD----SLATSIDPKEDHNYSASSMAAQRCASRSS---VSSLSSVDEVYE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 FATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKA : :.:. ::.:::: :.:.:. .:.. .: : ::::::::: XP_006 FIPKNSHVGSDGSEG-FHSEED-TDVDYED---------DPLGDSGYASQ--------PC 340 350 360 370 410 420 430 440 450 460 pF1KB7 RKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKET :. :: : . : : ::.::::::::::::::.::... . ::: :. ::. XP_006 AKISEKGQSGKKMRKQTCQEID-EELKEAAGSLLHLAGIRTCLGSLIS-TAKTQN-QKQR 380 390 400 410 420 pF1KB7 TKN : XP_006 KK 430 >>XP_016859446 (OMIM: 143089) PREDICTED: forkhead box pr (431 aa) initn: 926 init1: 571 opt: 740 Z-score: 570.3 bits: 114.7 E(85289): 5e-25 Smith-Waterman score: 1027; 44.0% identity (63.3% similar) in 482 aa overlap (1-467:1-431) 10 20 30 40 50 pF1KB7 MGPV--MPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDE :::: : :.:. :. : .:::: : ... .:. : . : : .. :. XP_016 MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAV------DAARPKATLVDSESADD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ELTNLNWLHESKNLLKSF--GESVLRSVSPVQDLDDDTPPS--PAHSDMPYDARQNPNCK ::::::::::: ::: .: : : :::. :.. : :: :: . : ... . : XP_016 ELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNP--EKKSATSK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKK :::::: ::.:::: ::.: ::::.::.:::.::::::.:::::::::::::::::::.: XP_016 PPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIW :.. ... :::::::.::::. :::::::: : :.. . :. : : . XP_016 VERSHGKVNGKGSLWCVDPEYKPNLIQALKKQP-------FSSASS-----QNGSLSPHY 180 190 200 210 220 240 250 260 270 280 pF1KB7 PGSTFFKRNGALLQVPPGVIQNGARVL-----SRGLFPGVRPLPI-TPIGVTAAMRNGI- :. .:.: . . .: .: .:.. .:::. : . .. :.. XP_016 L-SSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFH 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 --TSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYE .. :.. ::. : ..: :::::::::... . : .: .: :: ::.:. :: XP_016 HPSAVRLQ-ESD----SLATSIDPKEDHNYSASSMAAQRCASRSS---VSSLSSVDEVYE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 FATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKA : :.:. ::.:::: :.:.:. .:.. .: : ::::::::: XP_016 FIPKNSHVGSDGSEG-FHSEED-TDVDYED---------DPLGDSGYASQ--------PC 340 350 360 370 410 420 430 440 450 460 pF1KB7 RKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKET :. :: : . : : ::.::::::::::::::.::... . ::: :. ::. XP_016 AKISEKGQSGKKMRKQTCQEID-EELKEAAGSLLHLAGIRTCLGSLIS-TAKTQN-QKQR 380 390 400 410 420 pF1KB7 TKN : XP_016 KK 430 >>XP_016859448 (OMIM: 143089) PREDICTED: forkhead box pr (431 aa) initn: 926 init1: 571 opt: 740 Z-score: 570.3 bits: 114.7 E(85289): 5e-25 Smith-Waterman score: 1027; 44.0% identity (63.3% similar) in 482 aa overlap (1-467:1-431) 10 20 30 40 50 pF1KB7 MGPV--MPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDE :::: : :.:. :. : .:::: : ... .:. : . : : .. :. XP_016 MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAV------DAARPKATLVDSESADD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ELTNLNWLHESKNLLKSF--GESVLRSVSPVQDLDDDTPPS--PAHSDMPYDARQNPNCK ::::::::::: ::: .: : : :::. :.. : :: :: . : ... . : XP_016 ELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNP--EKKSATSK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKK :::::: ::.:::: ::.: ::::.::.:::.::::::.:::::::::::::::::::.: XP_016 PPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIW :.. ... :::::::.::::. :::::::: : :.. . :. : : . XP_016 VERSHGKVNGKGSLWCVDPEYKPNLIQALKKQP-------FSSASS-----QNGSLSPHY 180 190 200 210 220 240 250 260 270 280 pF1KB7 PGSTFFKRNGALLQVPPGVIQNGARVL-----SRGLFPGVRPLPI-TPIGVTAAMRNGI- :. .:.: . . .: .: .:.. .:::. : . .. :.. XP_016 L-SSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFH 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 --TSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYE .. :.. ::. : ..: :::::::::... . : .: .: :: ::.:. :: XP_016 HPSAVRLQ-ESD----SLATSIDPKEDHNYSASSMAAQRCASRSS---VSSLSSVDEVYE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 FATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKA : :.:. ::.:::: :.:.:. .:.. .: : ::::::::: XP_016 FIPKNSHVGSDGSEG-FHSEED-TDVDYED---------DPLGDSGYASQ--------PC 340 350 360 370 410 420 430 440 450 460 pF1KB7 RKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKET :. :: : . : : ::.::::::::::::::.::... . ::: :. ::. XP_016 AKISEKGQSGKKMRKQTCQEID-EELKEAAGSLLHLAGIRTCLGSLIS-TAKTQN-QKQR 380 390 400 410 420 pF1KB7 TKN : XP_016 KK 430 >>NP_002149 (OMIM: 143089) forkhead box protein N2 [Homo (431 aa) initn: 926 init1: 571 opt: 740 Z-score: 570.3 bits: 114.7 E(85289): 5e-25 Smith-Waterman score: 1027; 44.0% identity (63.3% similar) in 482 aa overlap (1-467:1-431) 10 20 30 40 50 pF1KB7 MGPV--MPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDE :::: : :.:. :. : .:::: : ... .:. : . : : .. :. NP_002 MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAV------DAARPKATLVDSESADD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ELTNLNWLHESKNLLKSF--GESVLRSVSPVQDLDDDTPPS--PAHSDMPYDARQNPNCK ::::::::::: ::: .: : : :::. :.. : :: :: . : ... . : NP_002 ELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNP--EKKSATSK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKK :::::: ::.:::: ::.: ::::.::.:::.::::::.:::::::::::::::::::.: NP_002 PPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIW :.. ... :::::::.::::. :::::::: : :.. . :. : : . NP_002 VERSHGKVNGKGSLWCVDPEYKPNLIQALKKQP-------FSSASS-----QNGSLSPHY 180 190 200 210 220 240 250 260 270 280 pF1KB7 PGSTFFKRNGALLQVPPGVIQNGARVL-----SRGLFPGVRPLPI-TPIGVTAAMRNGI- :. .:.: . . .: .: .:.. .:::. : . .. :.. NP_002 L-SSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFH 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 --TSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYE .. :.. ::. : ..: :::::::::... . : .: .: :: ::.:. :: NP_002 HPSAVRLQ-ESD----SLATSIDPKEDHNYSASSMAAQRCASRSS---VSSLSSVDEVYE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 FATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKA : :.:. ::.:::: :.:.:. .:.. .: : ::::::::: NP_002 FIPKNSHVGSDGSEG-FHSEED-TDVDYED---------DPLGDSGYASQ--------PC 340 350 360 370 410 420 430 440 450 460 pF1KB7 RKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKET :. :: : . : : ::.::::::::::::::.::... . ::: :. ::. NP_002 AKISEKGQSGKKMRKQTCQEID-EELKEAAGSLLHLAGIRTCLGSLIS-TAKTQN-QKQR 380 390 400 410 420 pF1KB7 TKN : NP_002 KK 430 468 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:57:36 2016 done: Sat Nov 5 18:57:38 2016 Total Scan time: 11.300 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]