Result of FASTA (omim) for
pF1KB7752
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7752, 490 aa
1>>>pF1KB7752 490 - 490 aa - 490 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9085+/-0.000326; mu= 16.4288+/- 0.020
mean_var=98.5679+/-20.415, 0's: 0 Z-trim(117.7): 410 B-trim: 1185 in 1/53
Lambda= 0.129183
statistics sampled from 29596 (30014) to 29596 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.352), width: 16
Scan time: 9.700
The best scores are: opt bits E(85289)
NP_001177848 (OMIM: 190120,614450) thyroid hormone ( 490) 3328 630.6 3.1e-180
NP_003241 (OMIM: 190120,614450) thyroid hormone re ( 490) 3328 630.6 3.1e-180
NP_001177847 (OMIM: 190120,614450) thyroid hormone ( 451) 2532 482.2 1.3e-135
NP_955366 (OMIM: 190120,614450) thyroid hormone re ( 410) 2527 481.2 2.3e-135
XP_016862602 (OMIM: 145650,188570,190160,274300) P ( 430) 1918 367.7 3.6e-101
XP_016862603 (OMIM: 145650,188570,190160,274300) P ( 430) 1918 367.7 3.6e-101
XP_011532355 (OMIM: 145650,188570,190160,274300) P ( 430) 1918 367.7 3.6e-101
XP_016862604 (OMIM: 145650,188570,190160,274300) P ( 430) 1918 367.7 3.6e-101
XP_016862597 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_011532349 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
NP_001121649 (OMIM: 145650,188570,190160,274300) t ( 461) 1918 367.8 3.8e-101
XP_016862599 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
NP_001121648 (OMIM: 145650,188570,190160,274300) t ( 461) 1918 367.8 3.8e-101
XP_016862598 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_005265481 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_016862601 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_011532354 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_005265480 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_011532352 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_005265478 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_006713380 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_011532350 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
NP_001239563 (OMIM: 145650,188570,190160,274300) t ( 461) 1918 367.8 3.8e-101
XP_016862600 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_011532348 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
NP_000452 (OMIM: 145650,188570,190160,274300) thyr ( 461) 1918 367.8 3.8e-101
XP_011532351 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_011532353 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
XP_006713381 (OMIM: 145650,188570,190160,274300) P ( 461) 1918 367.8 3.8e-101
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402) 656 132.5 2.1e-30
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols ( 402) 656 132.5 2.1e-30
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols ( 402) 656 132.5 2.1e-30
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols ( 402) 656 132.5 2.1e-30
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols ( 402) 656 132.5 2.1e-30
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols ( 402) 656 132.5 2.1e-30
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols ( 447) 656 132.6 2.3e-30
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols ( 447) 656 132.6 2.3e-30
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols ( 447) 656 132.6 2.3e-30
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols ( 447) 656 132.6 2.3e-30
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447) 656 132.6 2.3e-30
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols ( 447) 656 132.6 2.3e-30
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols ( 447) 656 132.6 2.3e-30
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453) 656 132.6 2.4e-30
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453) 656 132.6 2.4e-30
XP_016872545 (OMIM: 602423) PREDICTED: oxysterols ( 332) 589 120.0 1.1e-26
XP_016872546 (OMIM: 602423) PREDICTED: oxysterols ( 323) 581 118.5 2.9e-26
NP_001193906 (OMIM: 603826,617049) bile acid recep ( 476) 542 111.3 6.1e-24
XP_011537342 (OMIM: 603826,617049) PREDICTED: bile ( 476) 542 111.3 6.1e-24
NP_001193908 (OMIM: 603826,617049) bile acid recep ( 476) 542 111.3 6.1e-24
NP_001193922 (OMIM: 603826,617049) bile acid recep ( 486) 542 111.3 6.2e-24
>>NP_001177848 (OMIM: 190120,614450) thyroid hormone rec (490 aa)
initn: 3328 init1: 3328 opt: 3328 Z-score: 3356.8 bits: 630.6 E(85289): 3.1e-180
Smith-Waterman score: 3328; 100.0% identity (100.0% similar) in 490 aa overlap (1-490:1-490)
10 20 30 40 50 60
pF1KB7 MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 GEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVC
430 440 450 460 470 480
490
pF1KB7 EDLAGNAASP
::::::::::
NP_001 EDLAGNAASP
490
>>NP_003241 (OMIM: 190120,614450) thyroid hormone recept (490 aa)
initn: 3328 init1: 3328 opt: 3328 Z-score: 3356.8 bits: 630.6 E(85289): 3.1e-180
Smith-Waterman score: 3328; 100.0% identity (100.0% similar) in 490 aa overlap (1-490:1-490)
10 20 30 40 50 60
pF1KB7 MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 GEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVC
430 440 450 460 470 480
490
pF1KB7 EDLAGNAASP
::::::::::
NP_003 EDLAGNAASP
490
>>NP_001177847 (OMIM: 190120,614450) thyroid hormone rec (451 aa)
initn: 2529 init1: 2529 opt: 2532 Z-score: 2555.6 bits: 482.2 E(85289): 1.3e-135
Smith-Waterman score: 2982; 92.0% identity (92.0% similar) in 490 aa overlap (1-490:1-451)
10 20 30 40 50 60
pF1KB7 MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQL
:::::::::: :::::::::::
NP_001 PHFWPKLLMK---------------------------------------GPQVRQLEQQL
370 380
430 440 450 460 470 480
pF1KB7 GEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVC
390 400 410 420 430 440
490
pF1KB7 EDLAGNAASP
::::::::::
NP_001 EDLAGNAASP
450
>>NP_955366 (OMIM: 190120,614450) thyroid hormone recept (410 aa)
initn: 2527 init1: 2527 opt: 2527 Z-score: 2551.1 bits: 481.2 E(85289): 2.3e-135
Smith-Waterman score: 2527; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KB7 MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQL
::::::::::
NP_955 PHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFEDQEV
370 380 390 400 410
>>XP_016862602 (OMIM: 145650,188570,190160,274300) PREDI (430 aa)
initn: 1918 init1: 1918 opt: 1918 Z-score: 1937.4 bits: 367.7 E(85289): 3.6e-101
Smith-Waterman score: 1918; 82.7% identity (93.9% similar) in 330 aa overlap (41-370:64-393)
20 30 40 50 60 70
pF1KB7 GSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITC
::::::::::: ::::::::::::::::::
XP_016 SSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITC
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB7 EGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSK
:::::::::::::::::.:::::.. :::::.:::::: ::::::: :::: ::::::::
XP_016 EGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSK
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB7 RVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRK
:.:::::::.:::.::.::. .:. ..:::: :::.::. .:::: .::::::::::.::
XP_016 RLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRK
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB7 FLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIIL
:::.::::.:::. :.: ::::::::.:::::::::::::::::::::: ::::::::::
XP_016 FLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIIL
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB7 LKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFN
:::::::::::::::::::::.::::.::::: : :::::::::::::::.:: :::.::
XP_016 LKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFN
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB7 LDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMK
::::::::::::::::.:: :: ::..::: :...:::::::.:.:::.. :::::::::
XP_016 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB7 EREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPV
XP_016 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
400 410 420 430
>>XP_016862603 (OMIM: 145650,188570,190160,274300) PREDI (430 aa)
initn: 1918 init1: 1918 opt: 1918 Z-score: 1937.4 bits: 367.7 E(85289): 3.6e-101
Smith-Waterman score: 1918; 82.7% identity (93.9% similar) in 330 aa overlap (41-370:64-393)
20 30 40 50 60 70
pF1KB7 GSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITC
::::::::::: ::::::::::::::::::
XP_016 SSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITC
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB7 EGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSK
:::::::::::::::::.:::::.. :::::.:::::: ::::::: :::: ::::::::
XP_016 EGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSK
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB7 RVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRK
:.:::::::.:::.::.::. .:. ..:::: :::.::. .:::: .::::::::::.::
XP_016 RLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRK
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB7 FLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIIL
:::.::::.:::. :.: ::::::::.:::::::::::::::::::::: ::::::::::
XP_016 FLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIIL
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB7 LKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFN
:::::::::::::::::::::.::::.::::: : :::::::::::::::.:: :::.::
XP_016 LKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFN
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB7 LDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMK
::::::::::::::::.:: :: ::..::: :...:::::::.:.:::.. :::::::::
XP_016 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB7 EREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPV
XP_016 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
400 410 420 430
>>XP_011532355 (OMIM: 145650,188570,190160,274300) PREDI (430 aa)
initn: 1918 init1: 1918 opt: 1918 Z-score: 1937.4 bits: 367.7 E(85289): 3.6e-101
Smith-Waterman score: 1918; 82.7% identity (93.9% similar) in 330 aa overlap (41-370:64-393)
20 30 40 50 60 70
pF1KB7 GSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITC
::::::::::: ::::::::::::::::::
XP_011 SSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITC
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB7 EGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSK
:::::::::::::::::.:::::.. :::::.:::::: ::::::: :::: ::::::::
XP_011 EGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSK
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB7 RVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRK
:.:::::::.:::.::.::. .:. ..:::: :::.::. .:::: .::::::::::.::
XP_011 RLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRK
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB7 FLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIIL
:::.::::.:::. :.: ::::::::.:::::::::::::::::::::: ::::::::::
XP_011 FLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIIL
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB7 LKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFN
:::::::::::::::::::::.::::.::::: : :::::::::::::::.:: :::.::
XP_011 LKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFN
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB7 LDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMK
::::::::::::::::.:: :: ::..::: :...:::::::.:.:::.. :::::::::
XP_011 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB7 EREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPV
XP_011 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
400 410 420 430
>>XP_016862604 (OMIM: 145650,188570,190160,274300) PREDI (430 aa)
initn: 1918 init1: 1918 opt: 1918 Z-score: 1937.4 bits: 367.7 E(85289): 3.6e-101
Smith-Waterman score: 1918; 82.7% identity (93.9% similar) in 330 aa overlap (41-370:64-393)
20 30 40 50 60 70
pF1KB7 GSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITC
::::::::::: ::::::::::::::::::
XP_016 SSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITC
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB7 EGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSK
:::::::::::::::::.:::::.. :::::.:::::: ::::::: :::: ::::::::
XP_016 EGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSK
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB7 RVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRK
:.:::::::.:::.::.::. .:. ..:::: :::.::. .:::: .::::::::::.::
XP_016 RLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRK
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB7 FLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIIL
:::.::::.:::. :.: ::::::::.:::::::::::::::::::::: ::::::::::
XP_016 FLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIIL
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB7 LKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFN
:::::::::::::::::::::.::::.::::: : :::::::::::::::.:: :::.::
XP_016 LKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFN
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB7 LDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMK
::::::::::::::::.:: :: ::..::: :...:::::::.:.:::.. :::::::::
XP_016 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB7 EREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPV
XP_016 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
400 410 420 430
>>XP_016862597 (OMIM: 145650,188570,190160,274300) PREDI (461 aa)
initn: 1918 init1: 1918 opt: 1918 Z-score: 1937.0 bits: 367.8 E(85289): 3.8e-101
Smith-Waterman score: 1918; 82.7% identity (93.9% similar) in 330 aa overlap (41-370:95-424)
20 30 40 50 60 70
pF1KB7 GSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITC
::::::::::: ::::::::::::::::::
XP_016 SSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITC
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB7 EGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSK
:::::::::::::::::.:::::.. :::::.:::::: ::::::: :::: ::::::::
XP_016 EGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSK
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB7 RVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRK
:.:::::::.:::.::.::. .:. ..:::: :::.::. .:::: .::::::::::.::
XP_016 RLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRK
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB7 FLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIIL
:::.::::.:::. :.: ::::::::.:::::::::::::::::::::: ::::::::::
XP_016 FLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIIL
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB7 LKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFN
:::::::::::::::::::::.::::.::::: : :::::::::::::::.:: :::.::
XP_016 LKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFN
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB7 LDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMK
::::::::::::::::.:: :: ::..::: :...:::::::.:.:::.. :::::::::
XP_016 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB7 EREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPV
XP_016 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
430 440 450 460
>>XP_011532349 (OMIM: 145650,188570,190160,274300) PREDI (461 aa)
initn: 1918 init1: 1918 opt: 1918 Z-score: 1937.0 bits: 367.8 E(85289): 3.8e-101
Smith-Waterman score: 1918; 82.7% identity (93.9% similar) in 330 aa overlap (41-370:95-424)
20 30 40 50 60 70
pF1KB7 GSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITC
::::::::::: ::::::::::::::::::
XP_011 SSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITC
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB7 EGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSK
:::::::::::::::::.:::::.. :::::.:::::: ::::::: :::: ::::::::
XP_011 EGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSK
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB7 RVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRK
:.:::::::.:::.::.::. .:. ..:::: :::.::. .:::: .::::::::::.::
XP_011 RLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRK
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB7 FLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIIL
:::.::::.:::. :.: ::::::::.:::::::::::::::::::::: ::::::::::
XP_011 FLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIIL
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB7 LKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFN
:::::::::::::::::::::.::::.::::: : :::::::::::::::.:: :::.::
XP_011 LKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFN
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB7 LDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMK
::::::::::::::::.:: :: ::..::: :...:::::::.:.:::.. :::::::::
XP_011 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB7 EREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPV
XP_011 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
430 440 450 460
490 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:52:25 2016 done: Sat Nov 5 01:52:27 2016
Total Scan time: 9.700 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]