Result of FASTA (omim) for
pF1KB7757
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7757, 447 aa
1>>>pF1KB7757 447 - 447 aa - 447 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0904+/-0.000404; mu= 6.1584+/- 0.025
mean_var=292.5883+/-67.916, 0's: 0 Z-trim(120.3): 1620 B-trim: 3550 in 2/55
Lambda= 0.074980
statistics sampled from 33468 (35481) to 33468 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.416), width: 16
Scan time: 9.330
The best scores are: opt bits E(85289)
NP_003403 (OMIM: 600470,616602) zinc finger protei ( 447) 3133 352.6 1.2e-96
NP_003404 (OMIM: 300265,306955,314390) zinc finger ( 467) 1790 207.4 6.8e-53
NP_001317590 (OMIM: 300265,306955,314390) zinc fin ( 457) 1594 186.1 1.6e-46
NP_009060 (OMIM: 603073,609637) zinc finger protei ( 532) 1477 173.6 1.1e-42
NP_115529 (OMIM: 608948) zinc finger protein ZIC 4 ( 334) 1457 171.1 3.9e-42
NP_001161851 (OMIM: 608948) zinc finger protein ZI ( 372) 1457 171.2 4.1e-42
NP_001161850 (OMIM: 608948) zinc finger protein ZI ( 384) 1457 171.2 4.2e-42
XP_011519412 (OMIM: 603073,609637) PREDICTED: zinc ( 427) 1267 150.7 6.9e-36
XP_016862803 (OMIM: 608948) PREDICTED: zinc finger ( 291) 1003 122.0 2.2e-27
XP_005255698 (OMIM: 608539,611498) PREDICTED: zinc ( 524) 624 81.3 6.8e-15
NP_001305847 (OMIM: 608539,611498) zinc finger pro ( 524) 624 81.3 6.8e-15
NP_115964 (OMIM: 608539,611498) zinc finger protei ( 524) 624 81.3 6.8e-15
XP_005251445 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 607 79.6 2.9e-14
XP_011516069 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 607 79.6 2.9e-14
XP_005251444 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 607 79.6 2.9e-14
XP_005251443 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 607 79.7 3.1e-14
NP_689842 (OMIM: 610192,610199) zinc finger protei ( 775) 607 79.7 3.1e-14
XP_011516068 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 607 79.7 3.1e-14
XP_016869850 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 607 79.7 3.1e-14
XP_011516067 (OMIM: 610192,610199) PREDICTED: zinc ( 868) 607 79.7 3.3e-14
XP_011516066 (OMIM: 610192,610199) PREDICTED: zinc ( 930) 607 79.8 3.4e-14
XP_011516065 (OMIM: 610192,610199) PREDICTED: zinc ( 930) 607 79.8 3.4e-14
NP_001035878 (OMIM: 610192,610199) zinc finger pro ( 930) 607 79.8 3.4e-14
XP_011513576 (OMIM: 146510,165240,174200,174700,17 (1521) 606 79.9 5e-14
XP_016867486 (OMIM: 146510,165240,174200,174700,17 (1579) 606 80.0 5.1e-14
NP_000159 (OMIM: 146510,165240,174200,174700,17570 (1580) 606 80.0 5.1e-14
XP_011509276 (OMIM: 165230,610829,615849) PREDICTE (1444) 596 78.8 1e-13
XP_011509275 (OMIM: 165230,610829,615849) PREDICTE (1461) 596 78.8 1e-13
XP_011509273 (OMIM: 165230,610829,615849) PREDICTE (1521) 596 78.9 1.1e-13
XP_011509272 (OMIM: 165230,610829,615849) PREDICTE (1539) 596 78.9 1.1e-13
XP_011509274 (OMIM: 165230,610829,615849) PREDICTE (1553) 596 78.9 1.1e-13
XP_006712485 (OMIM: 165230,610829,615849) PREDICTE (1569) 596 78.9 1.1e-13
NP_005261 (OMIM: 165230,610829,615849) zinc finger (1586) 596 78.9 1.1e-13
XP_016859307 (OMIM: 165230,610829,615849) PREDICTE (1653) 596 78.9 1.1e-13
XP_011509271 (OMIM: 165230,610829,615849) PREDICTE (1670) 596 78.9 1.1e-13
NP_001161081 (OMIM: 165220) zinc finger protein GL (1065) 588 77.8 1.5e-13
XP_011536491 (OMIM: 165220) PREDICTED: zinc finger (1106) 588 77.8 1.6e-13
NP_005260 (OMIM: 165220) zinc finger protein GLI1 (1106) 588 77.8 1.6e-13
NP_001153517 (OMIM: 165220) zinc finger protein GL ( 978) 583 77.2 2.1e-13
XP_016855898 (OMIM: 610378) PREDICTED: zinc finger ( 791) 576 76.3 3.2e-13
NP_671726 (OMIM: 610378) zinc finger protein GLIS1 ( 620) 571 75.7 4e-13
XP_016855900 (OMIM: 610378) PREDICTED: zinc finger ( 629) 571 75.7 4e-13
XP_016855897 (OMIM: 610378) PREDICTED: zinc finger ( 795) 571 75.8 4.6e-13
XP_016855899 (OMIM: 610378) PREDICTED: zinc finger ( 795) 571 75.8 4.6e-13
XP_011536492 (OMIM: 165220) PREDICTED: zinc finger (1029) 483 66.4 4e-10
NP_001230185 (OMIM: 608948) zinc finger protein ZI ( 128) 464 63.2 4.7e-10
XP_005253184 (OMIM: 603433) PREDICTED: zinc finger ( 435) 456 63.0 1.8e-09
XP_016873745 (OMIM: 603433) PREDICTED: zinc finger ( 606) 456 63.2 2.2e-09
NP_001269586 (OMIM: 603433) zinc finger protein 14 ( 607) 456 63.2 2.2e-09
XP_016873742 (OMIM: 603433) PREDICTED: zinc finger ( 621) 456 63.2 2.2e-09
>>NP_003403 (OMIM: 600470,616602) zinc finger protein ZI (447 aa)
initn: 3133 init1: 3133 opt: 3133 Z-score: 1856.0 bits: 352.6 E(85289): 1.2e-96
Smith-Waterman score: 3133; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB7 MLLDAGPQYPAIGVTTFGASRHHSAGDVAERDVGLGINPFADGMGAFKLNPSSHELASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLLDAGPQYPAIGVTTFGASRHHSAGDVAERDVGLGINPFADGMGAFKLNPSSHELASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QTAFTSQAPGYAAAAALGHHHHPGHVGSYSSAAFNSTRDFLFRNRGFGDAAAAASAQHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QTAFTSQAPGYAAAAALGHHHHPGHVGSYSSAAFNSTRDFLFRNRGFGDAAAAASAQHSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASPNVVNGQMRLGFSGDMYPRPEQYGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASPNVVNGQMRLGFSGDMYPRPEQYGQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VTSPRSEHYAAPQLHGYGPMNVNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VTSPRSEHYAAPQLHGYGPMNVNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 PFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PYLCKMCDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PYLCKMCDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTS
370 380 390 400 410 420
430 440
pF1KB7 SLSPSSSAVHHTAGHSALSSNFNEWYV
:::::::::::::::::::::::::::
NP_003 SLSPSSSAVHHTAGHSALSSNFNEWYV
430 440
>>NP_003404 (OMIM: 300265,306955,314390) zinc finger pro (467 aa)
initn: 1851 init1: 1275 opt: 1790 Z-score: 1070.6 bits: 207.4 E(85289): 6.8e-53
Smith-Waterman score: 2017; 64.4% identity (81.7% similar) in 475 aa overlap (1-447:3-467)
10 20 30 40
pF1KB7 MLLDAGPQYPAIGVTTFGASRHHSAGDVAERDVGLGINPFADGM---------GAFKL
::::.:::.:..:: .::: ::: . .. .:.:.:::.:. .::::
NP_003 MTMLLDGGPQFPGLGVGSFGAPRHHEMPN--REPAGMGLNPFGDSTHAAAAAAAAAAFKL
10 20 30 40 50
50 60 70 80 90
pF1KB7 NPSS-HELASAGQTAFTSQAPGYAAAAALGHHHHPGH-------VGSY---SSAAFNSTR
.:.. :.:.:. ..::: :. ::: : :::::: : : :: .::::::::
NP_003 SPAAAHDLSSGQSSAFTPQGSGYANA--LGHHHHHHHHHHHTSQVPSYGGAASAAFNSTR
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB7 DFLFRNRGFG-DAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASP-
.::::.:. : . ::....::.:::.::... .: : . ..:::::::::.::: ::
NP_003 EFLFRQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPT
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 -NVVNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAA-PQLHGYGPMNVNM----AAHHGA
.: :.:..::. :... : . : :.:::.. ::: :. .:.:::.:: :::::
NP_003 GHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 GAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHI
::::::::::::::: ::::. ::. :::::..:::::::::::::.::::::::.::.
NP_003 GAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB7 CFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEK
:.::::::::: :::::::::::::::::::::::::::::.::::::::::::::::::
NP_003 CYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEK
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB7 PFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSSQG
::::::::::::::::::::::::::::::::.::.::::::::::::::::::: :::
NP_003 PFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHE--SQG
360 370 380 390 400 410
400 410 420 430 440
pF1KB7 SQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNEWYV
:. ::::::::::::::.:.: .. . ::.. : .... :. : : :::::::
NP_003 SDSSPAASSGYESSTPPAIASANSKD-TTKTPSAVQTSTSHNPG---LPPNFNEWYV
420 430 440 450 460
>>NP_001317590 (OMIM: 300265,306955,314390) zinc finger (457 aa)
initn: 1506 init1: 1233 opt: 1594 Z-score: 956.1 bits: 186.1 E(85289): 1.6e-46
Smith-Waterman score: 1821; 65.9% identity (83.0% similar) in 411 aa overlap (1-382:3-408)
10 20 30 40
pF1KB7 MLLDAGPQYPAIGVTTFGASRHHSAGDVAERD-VGLGINPFADGM---------GAFK
::::.:::.:..:: .::: ::: .. .:. .:.:.:::.:. .:::
NP_001 MTMLLDGGPQFPGLGVGSFGAPRHH---EMPNREPAGMGLNPFGDSTHAAAAAAAAAAFK
10 20 30 40 50
50 60 70 80 90
pF1KB7 LNPSS-HELASAGQTAFTSQAPGYAAAAALGHHHHPGH-------VGSY---SSAAFNST
:.:.. :.:.:. ..::: :. ::: : :::::: : : :: .:::::::
NP_001 LSPAAAHDLSSGQSSAFTPQGSGYANA--LGHHHHHHHHHHHTSQVPSYGGAASAAFNST
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB7 RDFLFRNRGFG-DAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASP
:.::::.:. : . ::....::.:::.::... .: : . ..:::::::::.::: ::
NP_001 REFLFRQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSP
120 130 140 150 160 170
160 170 180 190 200
pF1KB7 --NVVNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAA-PQLHGYGPMNVNM----AAHHG
.: :.:..::. :... : . : :.:::.. ::: :. .:.:::.:: :::::
NP_001 TGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHG
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 AGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNH
::::::::::::::: ::::. ::. :::::..:::::::::::::.::::::::.::
NP_001 PGAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNH
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB7 ICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGE
.:.::::::::: :::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 VCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGE
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB7 KPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSSQ
:::::::::::::::::::::::::::::::::.::.::::::::::::::::
NP_001 KPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKCCPAWYP
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB7 GSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNEWYV
NP_001 GQSLIPDEELDTDVGMQQPALHNTTYPKCRVNAEPTVQEMIY
420 430 440 450
>>NP_009060 (OMIM: 603073,609637) zinc finger protein ZI (532 aa)
initn: 2393 init1: 1400 opt: 1477 Z-score: 887.0 bits: 173.6 E(85289): 1.1e-42
Smith-Waterman score: 2154; 69.6% identity (83.3% similar) in 473 aa overlap (1-437:1-468)
10 20 30 40
pF1KB7 MLLDAGPQYPAIGVTTFGASRHHSAGDVA-------ERDVGLGI--NPFADG----MGAF
::::::::.::::: .:. .::::. .: .:...:. : :.:. ::::
NP_009 MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAF
10 20 30 40 50 60
50 60 70 80 90
pF1KB7 KLNPSSHELASAGQTAFTSQAPGY--------AAAAALGHHHHPGHVGSYSSAAFNSTRD
::::..:::. . ..:::::.:: ::::::: : .::::::. ::::::
NP_009 KLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGP--HAAHVGSYSGPPFNSTRD
70 80 90 100 110
100 110 120 130 140 150
pF1KB7 FLFRNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASPNVV
::::.:::::.: ... ::.::. .:::. :.:.:: :::::::: :: . :.: ::.
NP_009 FLFRSRGFGDSAPGGG-QHGLFGPGAGGLH--HAHSDAQGHLLFPGLPEQHGPHGSQNVL
120 130 140 150 160 170
160 170 180 190 200
pF1KB7 NGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQLHG-YGPMNVNM-------AAHHG--
:::::::. :... : ::: ::.:::.. :.: :::. :::::.:: ::::
NP_009 NGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHH
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 ----AGAFFRYMRQP-IKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGP
::::::::: ::::::::::.::::.::::::::::::::::::::.:::::::
NP_009 HHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB7 EQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKR
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKR
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB7 THTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVH
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 THTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVH
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB7 ESSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNE
::: :::. :::::::::::::: .::::.. ..:.:::...:. .:. .:
NP_009 ESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVH
420 430 440 450 460 470
pF1KB7 WYV
NP_009 RGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNFNEWYV
480 490 500 510 520 530
>>NP_115529 (OMIM: 608948) zinc finger protein ZIC 4 iso (334 aa)
initn: 1624 init1: 865 opt: 1457 Z-score: 877.5 bits: 171.1 E(85289): 3.9e-42
Smith-Waterman score: 1457; 68.2% identity (81.3% similar) in 321 aa overlap (122-436:23-333)
100 110 120 130 140 150
pF1KB7 AAFNSTRDFLFRNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAA
..:..: ::. : :.. .::::::.
NP_115 MRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQ-LTAASSPSVFPGLHEEPP
10 20 30 40 50
160 170 180 190 200
pF1KB7 GHASPNV-VNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQ-LHGYGPMN--VNMAAH
.:::. .:: .:::. :::: ::: . . ::. :: ::::: :: ::.::
NP_115 -QASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMNLTVNLAAP
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB7 HGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQS
:: :::::::::::::::::::. . :.:. :.:::::::::::::::::::::::.
NP_115 HGPGAFFRYMRQPIKQELICKWLAADGTATPSL-CSKTFSTMHELVTHVTVEHVGGPEQA
120 130 140 150 160
270 280 290 300 310 320
pF1KB7 NHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHT
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 NHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHT
170 180 190 200 210 220
330 340 350 360 370 380
pF1KB7 GEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHE
:::::.::::::.:::::::::::: ::::::::: ::. ::: ::::::::::::::
NP_115 GEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVH-
230 240 250 260 270 280
390 400 410 420 430 440
pF1KB7 SSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNEW
: .: : ::::.:.:: ..::::.: :... :.... .:: :
NP_115 ----GRSPPP--SSGYDSATPSALVSPSSDCGHKSQVASSAAVAARTADLSE
290 300 310 320 330
pF1KB7 YV
>>NP_001161851 (OMIM: 608948) zinc finger protein ZIC 4 (372 aa)
initn: 1624 init1: 865 opt: 1457 Z-score: 877.0 bits: 171.2 E(85289): 4.1e-42
Smith-Waterman score: 1457; 68.2% identity (81.3% similar) in 321 aa overlap (122-436:61-371)
100 110 120 130 140 150
pF1KB7 AAFNSTRDFLFRNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAA
..:..: ::. : :.. .::::::.
NP_001 DSKAQSQKMRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQ-LTAASSPSVFPGLHEEPP
40 50 60 70 80
160 170 180 190 200
pF1KB7 GHASPNV-VNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQ-LHGYGPMN--VNMAAH
.:::. .:: .:::. :::: ::: . . ::. :: ::::: :: ::.::
NP_001 -QASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMNLTVNLAAP
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB7 HGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQS
:: :::::::::::::::::::. . :.:. :.:::::::::::::::::::::::.
NP_001 HGPGAFFRYMRQPIKQELICKWLAADGTATPSL-CSKTFSTMHELVTHVTVEHVGGPEQA
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB7 NHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHT
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHT
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB7 GEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHE
:::::.::::::.:::::::::::: ::::::::: ::. ::: ::::::::::::::
NP_001 GEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVH-
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB7 SSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNEW
: .: : ::::.:.:: ..::::.: :... :.... .:: :
NP_001 ----GRSPPP--SSGYDSATPSALVSPSSDCGHKSQVASSAAVAARTADLSE
330 340 350 360 370
pF1KB7 YV
>>NP_001161850 (OMIM: 608948) zinc finger protein ZIC 4 (384 aa)
initn: 1624 init1: 865 opt: 1457 Z-score: 876.9 bits: 171.2 E(85289): 4.2e-42
Smith-Waterman score: 1457; 68.2% identity (81.3% similar) in 321 aa overlap (122-436:73-383)
100 110 120 130 140 150
pF1KB7 AAFNSTRDFLFRNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAA
..:..: ::. : :.. .::::::.
NP_001 WEKAQSQKMRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQ-LTAASSPSVFPGLHEEPP
50 60 70 80 90 100
160 170 180 190 200
pF1KB7 GHASPNV-VNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQ-LHGYGPMN--VNMAAH
.:::. .:: .:::. :::: ::: . . ::. :: ::::: :: ::.::
NP_001 -QASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMNLTVNLAAP
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB7 HGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQS
:: :::::::::::::::::::. . :.:. :.:::::::::::::::::::::::.
NP_001 HGPGAFFRYMRQPIKQELICKWLAADGTATPSL-CSKTFSTMHELVTHVTVEHVGGPEQA
170 180 190 200 210
270 280 290 300 310 320
pF1KB7 NHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHT
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHT
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB7 GEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHE
:::::.::::::.:::::::::::: ::::::::: ::. ::: ::::::::::::::
NP_001 GEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVH-
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB7 SSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNEW
: .: : ::::.:.:: ..::::.: :... :.... .:: :
NP_001 ----GRSPPP--SSGYDSATPSALVSPSSDCGHKSQVASSAAVAARTADLSE
340 350 360 370 380
pF1KB7 YV
>>XP_011519412 (OMIM: 603073,609637) PREDICTED: zinc fin (427 aa)
initn: 1855 init1: 1190 opt: 1267 Z-score: 765.3 bits: 150.7 E(85289): 6.9e-36
Smith-Waterman score: 1944; 70.8% identity (83.0% similar) in 418 aa overlap (1-382:1-413)
10 20 30 40
pF1KB7 MLLDAGPQYPAIGVTTFGASRHHSAGDVA-------ERDVGLGI--NPFADG----MGAF
::::::::.::::: .:. .::::. .: .:...:. : :.:. ::::
XP_011 MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAF
10 20 30 40 50 60
50 60 70 80 90
pF1KB7 KLNPSSHELASAGQTAFTSQAPGY--------AAAAALGHHHHPGHVGSYSSAAFNSTRD
::::..:::. . ..:::::.:: ::::::: : .::::::. ::::::
XP_011 KLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPH--AAHVGSYSGPPFNSTRD
70 80 90 100 110
100 110 120 130 140 150
pF1KB7 FLFRNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASPNVV
::::.:::::.: ... ::.::. .:::. :.:.:: :::::::: :: . :.: ::.
XP_011 FLFRSRGFGDSAPGGG-QHGLFGPGAGGLH--HAHSDAQGHLLFPGLPEQHGPHGSQNVL
120 130 140 150 160 170
160 170 180 190 200
pF1KB7 NGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQLHG-YGPMNVNM-------AAHHG--
:::::::. :... : ::: ::.:::.. :.: :::. :::::.:: ::::
XP_011 NGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHH
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 ----AGAFFRYMRQP-IKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGP
::::::::: ::::::::::.::::.::::::::::::::::::::.:::::::
XP_011 HHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB7 EQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKR
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKR
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB7 THTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVH
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKSP
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB7 ESSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNE
XP_011 LVPPPGFCLAGP
420
>>XP_016862803 (OMIM: 608948) PREDICTED: zinc finger pro (291 aa)
initn: 1126 init1: 609 opt: 1003 Z-score: 612.8 bits: 122.0 E(85289): 2.2e-27
Smith-Waterman score: 1003; 68.5% identity (81.3% similar) in 219 aa overlap (122-336:73-288)
100 110 120 130 140 150
pF1KB7 AAFNSTRDFLFRNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAA
..:..: ::. : :.. .::::::.
XP_016 WEKAQSQKMRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQ-LTAASSPSVFPGLHEEPP
50 60 70 80 90 100
160 170 180 190 200
pF1KB7 GHASPNV-VNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQ-LHGYGPMN--VNMAAH
.:::. .:: .:::. :::: ::: . . ::. :: ::::: :: ::.::
XP_016 -QASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMNLTVNLAAP
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB7 HGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQS
:: :::::::::::::::::::. . :.:. :.:::::::::::::::::::::::.
XP_016 HGPGAFFRYMRQPIKQELICKWLAADGTATPSL-CSKTFSTMHELVTHVTVEHVGGPEQA
170 180 190 200 210
270 280 290 300 310 320
pF1KB7 NHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHT
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHT
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB7 GEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESS
.: . .:
XP_016 AEAANRSKFLRS
280 290
>>XP_005255698 (OMIM: 608539,611498) PREDICTED: zinc fin (524 aa)
initn: 548 init1: 298 opt: 624 Z-score: 388.4 bits: 81.3 E(85289): 6.8e-15
Smith-Waterman score: 629; 36.8% identity (59.5% similar) in 304 aa overlap (151-438:87-370)
130 140 150 160 170
pF1KB7 FAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASPNVVNG--QMRLGFSGDMYPRPEQY
.: ::: .. : : .::. : :
XP_005 SGFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQG-NGDLPPVPSAS
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB7 GQVTSPRSEHYAAPQ-LHGYGPMNVNMAAHHGAGAFFRYMRQ-------PIKQELICKWI
.: ..:. .. . :.. . : : :..:. .. :. ..:.:.:
XP_005 D--FQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWA
120 130 140 150 160 170
240 250 260 270 280 290
pF1KB7 EPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLV
. ::. : ...:: ::. :: ..... : :: : :.:. :.:.::..
XP_005 K----------CNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKML
180 190 200 210 220
300 310 320 330 340 350
pF1KB7 NHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRK
:::.::.::: :: :.: :.: ::::::.:.::::::. : .:::..:..:::::
XP_005 IHIRTHTNEKPHRCP--TCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRF
230 240 250 260 270 280
360 370 380 390 400
pF1KB7 KHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPT
:: ..: :::: ::: : : :: :::::::.:.: : : . . ::
XP_005 KHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAH-----GHFVSHEQQELLQLRPPPK
290 300 310 320 330
410 420 430 440
pF1KB7 IVSPSTDN-PTTSS---LSPSSSAVHHTAGHSALSSNFNEWYV
:. :. : .:. . :. .:. : .:
XP_005 PPLPAPDGGPYVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGG
340 350 360 370 380 390
XP_005 GMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRAL
400 410 420 430 440 450
447 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:10:54 2016 done: Fri Nov 4 22:10:55 2016
Total Scan time: 9.330 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]