FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7763, 448 aa 1>>>pF1KB7763 448 - 448 aa - 448 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2680+/-0.00143; mu= -0.7438+/- 0.085 mean_var=227.7514+/-46.466, 0's: 0 Z-trim(106.9): 192 B-trim: 253 in 1/50 Lambda= 0.084985 statistics sampled from 9023 (9228) to 9023 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.283), width: 16 Scan time: 3.250 The best scores are: opt bits E(32554) CCDS983.1 GABPB2 gene_id:126626|Hs108|chr1 ( 448) 2812 358.2 9.7e-99 CCDS32239.1 GABPB1 gene_id:2553|Hs108|chr15 ( 395) 1646 215.2 9.6e-56 CCDS45258.1 GABPB1 gene_id:2553|Hs108|chr15 ( 360) 1449 191.0 1.7e-48 CCDS81373.1 GABPB2 gene_id:126626|Hs108|chr1 ( 410) 1338 177.4 2.3e-44 CCDS10135.1 GABPB1 gene_id:2553|Hs108|chr15 ( 383) 985 134.1 2.3e-31 CCDS10136.1 GABPB1 gene_id:2553|Hs108|chr15 ( 348) 955 130.4 2.8e-30 >>CCDS983.1 GABPB2 gene_id:126626|Hs108|chr1 (448 aa) initn: 2812 init1: 2812 opt: 2812 Z-score: 1886.1 bits: 358.2 E(32554): 9.7e-99 Smith-Waterman score: 2812; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AAPFIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 AAPFIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLSN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 SHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFIV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 TVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 TVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 LQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEGE 370 380 390 400 410 420 430 440 pF1KB7 LEERETKVTGSAGTTEPHTRVSMATVSS :::::::::::::::::::::::::::: CCDS98 LEERETKVTGSAGTTEPHTRVSMATVSS 430 440 >>CCDS32239.1 GABPB1 gene_id:2553|Hs108|chr15 (395 aa) initn: 1501 init1: 1072 opt: 1646 Z-score: 1114.3 bits: 215.2 E(32554): 9.6e-56 Smith-Waterman score: 1646; 68.5% identity (86.2% similar) in 400 aa overlap (1-398:1-391) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: CCDS32 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: CCDS32 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . CCDS32 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : ::::..:.:: :.. .. . .:.:::.::.::::::::::::::.::: CCDS32 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. CCDS32 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: CCDS32 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE .::.::::.::.::.:::::::::: :: ::::..: : : CCDS32 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 360 370 380 390 420 430 440 pF1KB7 GELEERETKVTGSAGTTEPHTRVSMATVSS >>CCDS45258.1 GABPB1 gene_id:2553|Hs108|chr15 (360 aa) initn: 1619 init1: 1072 opt: 1449 Z-score: 984.3 bits: 191.0 E(32554): 1.7e-48 Smith-Waterman score: 1449; 67.7% identity (85.5% similar) in 359 aa overlap (1-357:1-350) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: CCDS45 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: CCDS45 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . CCDS45 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : ::::..:.:: :.. .. . .:.:::.::.::::::::::::::.::: CCDS45 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. CCDS45 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : . : :: CCDS45 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEVRSLLP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE CCDS45 GVLCRSHPK 360 >>CCDS81373.1 GABPB2 gene_id:126626|Hs108|chr1 (410 aa) initn: 1522 init1: 1325 opt: 1338 Z-score: 910.0 bits: 177.4 E(32554): 2.3e-44 Smith-Waterman score: 2498; 91.5% identity (91.5% similar) in 448 aa overlap (1-448:1-410) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AAPFIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLSN ::::::::::::::::::::::::::: CCDS81 AAPFIFTSGEVVNLASLISSTNTKTTS--------------------------------- 190 200 250 260 270 280 290 300 pF1KB7 SHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFIV ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 -----ANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFIV 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB7 TVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 TVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQQ 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB7 LQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEGE 330 340 350 360 370 380 430 440 pF1KB7 LEERETKVTGSAGTTEPHTRVSMATVSS :::::::::::::::::::::::::::: CCDS81 LEERETKVTGSAGTTEPHTRVSMATVSS 390 400 410 >>CCDS10135.1 GABPB1 gene_id:2553|Hs108|chr15 (383 aa) initn: 1471 init1: 914 opt: 985 Z-score: 676.5 bits: 134.1 E(32554): 2.3e-31 Smith-Waterman score: 1586; 67.5% identity (83.8% similar) in 400 aa overlap (1-398:1-379) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: CCDS10 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: CCDS10 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . CCDS10 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : :::: . . .:.:::.::.::::::::::::::.::: CCDS10 ATPQFIIGPGGVVNL------------TDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. CCDS10 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: CCDS10 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE .::.::::.::.::.:::::::::: :: ::::..: : : CCDS10 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 340 350 360 370 380 420 430 440 pF1KB7 GELEERETKVTGSAGTTEPHTRVSMATVSS >>CCDS10136.1 GABPB1 gene_id:2553|Hs108|chr15 (348 aa) initn: 1411 init1: 914 opt: 955 Z-score: 657.2 bits: 130.4 E(32554): 2.8e-30 Smith-Waterman score: 1389; 66.6% identity (82.7% similar) in 359 aa overlap (1-357:1-338) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: CCDS10 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: CCDS10 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . CCDS10 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : :::: . . .:.:::.::.::::::::::::::.::: CCDS10 ATPQFIIGPGGVVNL------------TDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. CCDS10 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : . : :: CCDS10 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEVRSLLP 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE CCDS10 GVLCRSHPK 340 448 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:12:13 2016 done: Fri Nov 4 22:12:13 2016 Total Scan time: 3.250 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]