FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7763, 448 aa 1>>>pF1KB7763 448 - 448 aa - 448 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1284+/-0.000612; mu= 0.8043+/- 0.038 mean_var=324.1058+/-67.197, 0's: 0 Z-trim(114.9): 485 B-trim: 804 in 1/51 Lambda= 0.071241 statistics sampled from 24522 (25078) to 24522 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.294), width: 16 Scan time: 9.860 The best scores are: opt bits E(85289) NP_001307844 (OMIM: 600610) GA-binding protein sub ( 394) 1657 184.6 3.9e-46 NP_005245 (OMIM: 600610) GA-binding protein subuni ( 395) 1646 183.5 8.6e-46 XP_005254331 (OMIM: 600610) PREDICTED: GA-binding ( 395) 1646 183.5 8.6e-46 NP_001307839 (OMIM: 600610) GA-binding protein sub ( 395) 1646 183.5 8.6e-46 NP_002032 (OMIM: 600610) GA-binding protein subuni ( 360) 1449 163.2 1e-39 XP_011519728 (OMIM: 600610) PREDICTED: GA-binding ( 382) 994 116.5 1.3e-25 XP_016877543 (OMIM: 600610) PREDICTED: GA-binding ( 382) 994 116.5 1.3e-25 XP_016877542 (OMIM: 600610) PREDICTED: GA-binding ( 383) 985 115.6 2.4e-25 NP_057738 (OMIM: 600610) GA-binding protein subuni ( 383) 985 115.6 2.4e-25 NP_057739 (OMIM: 600610) GA-binding protein subuni ( 348) 955 112.4 1.9e-24 NP_852092 (OMIM: 600610) GA-binding protein subuni ( 348) 955 112.4 1.9e-24 XP_016865998 (OMIM: 610583) PREDICTED: ankyrin rep ( 626) 317 47.2 0.00015 XP_016865995 (OMIM: 610583) PREDICTED: ankyrin rep ( 656) 317 47.2 0.00016 XP_016865990 (OMIM: 610583) PREDICTED: ankyrin rep ( 661) 317 47.2 0.00016 XP_016872190 (OMIM: 607128) PREDICTED: tankyrase-2 ( 506) 308 46.1 0.00025 XP_016872188 (OMIM: 607128) PREDICTED: tankyrase-2 (1059) 308 46.5 0.00041 XP_016872186 (OMIM: 607128) PREDICTED: tankyrase-2 (1062) 308 46.5 0.00041 XP_016872187 (OMIM: 607128) PREDICTED: tankyrase-2 (1062) 308 46.5 0.00041 XP_016865993 (OMIM: 610583) PREDICTED: ankyrin rep ( 659) 303 45.7 0.00043 NP_079511 (OMIM: 607128) tankyrase-2 [Homo sapiens (1166) 308 46.5 0.00043 XP_016872185 (OMIM: 607128) PREDICTED: tankyrase-2 (1169) 308 46.5 0.00044 XP_011538515 (OMIM: 607128) PREDICTED: tankyrase-2 (1187) 308 46.6 0.00044 XP_005270242 (OMIM: 607128) PREDICTED: tankyrase-2 (1190) 308 46.6 0.00044 XP_016863597 (OMIM: 106410,600919) PREDICTED: anky (1772) 310 47.0 0.0005 XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797) 310 47.0 0.0005 XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806) 310 47.0 0.0005 XP_016863589 (OMIM: 106410,600919) PREDICTED: anky (1846) 310 47.0 0.00051 XP_016863586 (OMIM: 106410,600919) PREDICTED: anky (1858) 310 47.0 0.00051 XP_016863580 (OMIM: 106410,600919) PREDICTED: anky (1879) 310 47.0 0.00051 XP_016865987 (OMIM: 610583) PREDICTED: ankyrin rep ( 687) 293 44.7 0.0009 XP_016865986 (OMIM: 610583) PREDICTED: ankyrin rep ( 689) 293 44.7 0.0009 NP_001229742 (OMIM: 610583) ankyrin repeat domain- ( 692) 293 44.7 0.0009 XP_016865984 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 293 44.7 0.0009 NP_055757 (OMIM: 610583) ankyrin repeat domain-con ( 722) 293 44.8 0.00093 XP_005248738 (OMIM: 610583) PREDICTED: ankyrin rep ( 727) 293 44.8 0.00093 NP_001229740 (OMIM: 610583) ankyrin repeat domain- ( 727) 293 44.8 0.00093 NP_001229738 (OMIM: 610583) ankyrin repeat domain- ( 727) 293 44.8 0.00093 XP_016865996 (OMIM: 610583) PREDICTED: ankyrin rep ( 656) 292 44.6 0.00094 XP_016866001 (OMIM: 610583) PREDICTED: ankyrin rep ( 567) 289 44.2 0.0011 XP_016866002 (OMIM: 610583) PREDICTED: ankyrin rep ( 567) 289 44.2 0.0011 XP_011542148 (OMIM: 603303) PREDICTED: tankyrase-1 (1301) 294 45.2 0.0013 XP_006716326 (OMIM: 603303) PREDICTED: tankyrase-1 (1316) 294 45.2 0.0013 XP_011542147 (OMIM: 603303) PREDICTED: tankyrase-1 (1316) 294 45.2 0.0013 NP_003738 (OMIM: 603303) tankyrase-1 [Homo sapiens (1327) 294 45.2 0.0013 NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform (1719) 293 45.2 0.0016 XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751) 293 45.2 0.0016 XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752) 293 45.2 0.0017 XP_016868818 (OMIM: 182900,612641) PREDICTED: anky (1759) 293 45.2 0.0017 XP_011542805 (OMIM: 182900,612641) PREDICTED: anky (1791) 293 45.2 0.0017 XP_016868817 (OMIM: 182900,612641) PREDICTED: anky (1792) 293 45.2 0.0017 >>NP_001307844 (OMIM: 600610) GA-binding protein subunit (394 aa) initn: 1697 init1: 920 opt: 1657 Z-score: 949.2 bits: 184.6 E(85289): 3.9e-46 Smith-Waterman score: 1657; 68.7% identity (86.2% similar) in 399 aa overlap (1-398:1-390) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: NP_001 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: NP_001 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . NP_001 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : ::::..:.:: :.. .. . .:.:::.::.::::::::::::::.::: NP_001 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NSHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFI :: .. . :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::.: NP_001 NSSETPVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPII 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 VTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQ ::. :::::::::: .::::::.:: : .:. : : :: : : .::: ::. NP_001 VTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQK 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 QLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEG ::.::::.::.::.:::::::::: :: ::::..: : : NP_001 QLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 360 370 380 390 420 430 440 pF1KB7 ELEERETKVTGSAGTTEPHTRVSMATVSS >>NP_005245 (OMIM: 600610) GA-binding protein subunit be (395 aa) initn: 1501 init1: 1072 opt: 1646 Z-score: 943.1 bits: 183.5 E(85289): 8.6e-46 Smith-Waterman score: 1646; 68.5% identity (86.2% similar) in 400 aa overlap (1-398:1-391) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: NP_005 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: NP_005 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . NP_005 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : ::::..:.:: :.. .. . .:.:::.::.::::::::::::::.::: NP_005 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. NP_005 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: NP_005 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE .::.::::.::.::.:::::::::: :: ::::..: : : NP_005 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 360 370 380 390 420 430 440 pF1KB7 GELEERETKVTGSAGTTEPHTRVSMATVSS >>XP_005254331 (OMIM: 600610) PREDICTED: GA-binding prot (395 aa) initn: 1501 init1: 1072 opt: 1646 Z-score: 943.1 bits: 183.5 E(85289): 8.6e-46 Smith-Waterman score: 1646; 68.5% identity (86.2% similar) in 400 aa overlap (1-398:1-391) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: XP_005 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: XP_005 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . XP_005 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : ::::..:.:: :.. .. . .:.:::.::.::::::::::::::.::: XP_005 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. XP_005 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: XP_005 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE .::.::::.::.::.:::::::::: :: ::::..: : : XP_005 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 360 370 380 390 420 430 440 pF1KB7 GELEERETKVTGSAGTTEPHTRVSMATVSS >>NP_001307839 (OMIM: 600610) GA-binding protein subunit (395 aa) initn: 1501 init1: 1072 opt: 1646 Z-score: 943.1 bits: 183.5 E(85289): 8.6e-46 Smith-Waterman score: 1646; 68.5% identity (86.2% similar) in 400 aa overlap (1-398:1-391) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: NP_001 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: NP_001 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . NP_001 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : ::::..:.:: :.. .. . .:.:::.::.::::::::::::::.::: NP_001 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. NP_001 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: NP_001 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE .::.::::.::.::.:::::::::: :: ::::..: : : NP_001 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 360 370 380 390 420 430 440 pF1KB7 GELEERETKVTGSAGTTEPHTRVSMATVSS >>NP_002032 (OMIM: 600610) GA-binding protein subunit be (360 aa) initn: 1619 init1: 1072 opt: 1449 Z-score: 834.1 bits: 163.2 E(85289): 1e-39 Smith-Waterman score: 1449; 67.7% identity (85.5% similar) in 359 aa overlap (1-357:1-350) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: NP_002 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: NP_002 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . NP_002 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : ::::..:.:: :.. .. . .:.:::.::.::::::::::::::.::: NP_002 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. NP_002 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : . : :: NP_002 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEVRSLLP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE NP_002 GVLCRSHPK 360 >>XP_011519728 (OMIM: 600610) PREDICTED: GA-binding prot (382 aa) initn: 1494 init1: 914 opt: 994 Z-score: 581.1 bits: 116.5 E(85289): 1.3e-25 Smith-Waterman score: 1597; 67.7% identity (83.7% similar) in 399 aa overlap (1-398:1-378) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: XP_011 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: XP_011 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . XP_011 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : :::: . . .:.:::.::.::::::::::::::.::: XP_011 ATPQFIIGPGGVVNL------------TDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 NSHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFI :: .. . :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::.: XP_011 NSSETPVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPII 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 VTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQ ::. :::::::::: .::::::.:: : .:. : : :: : : .::: ::. XP_011 VTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQK 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 QLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEG ::.::::.::.::.:::::::::: :: ::::..: : : XP_011 QLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 340 350 360 370 380 420 430 440 pF1KB7 ELEERETKVTGSAGTTEPHTRVSMATVSS >>XP_016877543 (OMIM: 600610) PREDICTED: GA-binding prot (382 aa) initn: 1494 init1: 914 opt: 994 Z-score: 581.1 bits: 116.5 E(85289): 1.3e-25 Smith-Waterman score: 1597; 67.7% identity (83.7% similar) in 399 aa overlap (1-398:1-378) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: XP_016 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: XP_016 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . XP_016 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : :::: . . .:.:::.::.::::::::::::::.::: XP_016 ATPQFIIGPGGVVNL------------TDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 NSHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFI :: .. . :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::.: XP_016 NSSETPVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPII 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 VTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQ ::. :::::::::: .::::::.:: : .:. : : :: : : .::: ::. XP_016 VTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQK 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 QLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEG ::.::::.::.::.:::::::::: :: ::::..: : : XP_016 QLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 340 350 360 370 380 420 430 440 pF1KB7 ELEERETKVTGSAGTTEPHTRVSMATVSS >>XP_016877542 (OMIM: 600610) PREDICTED: GA-binding prot (383 aa) initn: 1471 init1: 914 opt: 985 Z-score: 576.1 bits: 115.6 E(85289): 2.4e-25 Smith-Waterman score: 1586; 67.5% identity (83.8% similar) in 400 aa overlap (1-398:1-379) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: XP_016 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: XP_016 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . XP_016 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : :::: . . .:.:::.::.::::::::::::::.::: XP_016 ATPQFIIGPGGVVNL------------TDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. XP_016 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: XP_016 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE .::.::::.::.::.:::::::::: :: ::::..: : : XP_016 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 340 350 360 370 380 420 430 440 pF1KB7 GELEERETKVTGSAGTTEPHTRVSMATVSS >>NP_057738 (OMIM: 600610) GA-binding protein subunit be (383 aa) initn: 1471 init1: 914 opt: 985 Z-score: 576.1 bits: 115.6 E(85289): 2.4e-25 Smith-Waterman score: 1586; 67.5% identity (83.8% similar) in 400 aa overlap (1-398:1-379) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: NP_057 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: NP_057 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . NP_057 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : :::: . . .:.:::.::.::::::::::::::.::: NP_057 ATPQFIIGPGGVVNL------------TDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. NP_057 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: NP_057 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE .::.::::.::.::.:::::::::: :: ::::..: : : NP_057 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 340 350 360 370 380 420 430 440 pF1KB7 GELEERETKVTGSAGTTEPHTRVSMATVSS >>NP_057739 (OMIM: 600610) GA-binding protein subunit be (348 aa) initn: 1411 init1: 914 opt: 955 Z-score: 559.9 bits: 112.4 E(85289): 1.9e-24 Smith-Waterman score: 1389; 66.6% identity (82.7% similar) in 359 aa overlap (1-357:1-338) 10 20 30 40 50 60 pF1KB7 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: NP_057 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: NP_057 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . NP_057 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA 130 140 150 160 170 190 200 210 220 230 pF1KB7 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS :.: ::. : :::: . . .:.:::.::.::::::::::::::.::: NP_057 ATPQFIIGPGGVVNL------------TDETGVSAVQFGNSSTSVLATLAALAEASAPLS 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. NP_057 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ :::. :::::::::: .::::::.:: : .:. : : :: : : . : :: NP_057 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEVRSLLP 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE NP_057 GVLCRSHPK 340 448 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:12:14 2016 done: Fri Nov 4 22:12:15 2016 Total Scan time: 9.860 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]