Result of FASTA (omim) for
pF1KB7772
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7772, 505 aa
1>>>pF1KB7772 505 - 505 aa - 505 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7968+/-0.000321; mu= 4.0478+/- 0.020
mean_var=224.3412+/-45.363, 0's: 0 Z-trim(123.0): 141 B-trim: 393 in 1/57
Lambda= 0.085629
statistics sampled from 41925 (42074) to 41925 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.493), width: 16
Scan time: 11.450
The best scores are: opt bits E(85289)
NP_005929 (OMIM: 300033) forkhead box protein O4 i ( 505) 3425 435.7 1.6e-121
NP_001164402 (OMIM: 300033) forkhead box protein O ( 450) 2640 338.6 2.2e-92
XP_011529259 (OMIM: 300033) PREDICTED: forkhead bo ( 327) 2185 282.3 1.5e-75
NP_001278210 (OMIM: 611457) forkhead box protein O ( 559) 962 131.4 6.6e-30
NP_002006 (OMIM: 136533,268220) forkhead box prote ( 655) 944 129.3 3.5e-29
NP_963853 (OMIM: 602681) forkhead box protein O3 [ ( 673) 926 127.0 1.7e-28
NP_001446 (OMIM: 602681) forkhead box protein O3 [ ( 673) 926 127.0 1.7e-28
XP_011533310 (OMIM: 136533,268220) PREDICTED: fork ( 474) 592 85.7 3.3e-16
XP_011533928 (OMIM: 602681) PREDICTED: forkhead bo ( 506) 527 77.7 9.2e-14
XP_005266924 (OMIM: 602681) PREDICTED: forkhead bo ( 484) 526 77.5 9.7e-14
XP_016866074 (OMIM: 602681) PREDICTED: forkhead bo ( 484) 526 77.5 9.7e-14
XP_011533930 (OMIM: 602681) PREDICTED: forkhead bo ( 453) 439 66.7 1.6e-10
XP_005266925 (OMIM: 602681) PREDICTED: forkhead bo ( 453) 439 66.7 1.6e-10
XP_011533931 (OMIM: 602681) PREDICTED: forkhead bo ( 453) 439 66.7 1.6e-10
XP_016866075 (OMIM: 602681) PREDICTED: forkhead bo ( 453) 439 66.7 1.6e-10
XP_011533312 (OMIM: 136533,268220) PREDICTED: fork ( 418) 416 63.9 1.1e-09
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 322 52.3 3.4e-06
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 301 49.7 2.3e-05
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 285 47.7 7.7e-05
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 284 47.5 8e-05
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 281 47.2 0.0001
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 283 47.5 0.00011
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 284 47.7 0.00011
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 284 47.7 0.00011
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 284 47.7 0.00011
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 277 46.6 0.00014
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 281 47.3 0.00014
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 273 46.3 0.00029
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 273 46.3 0.0003
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 273 46.3 0.0003
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 273 46.3 0.0003
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 273 46.3 0.0003
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 273 46.4 0.0003
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 265 45.4 0.00062
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 252 43.5 0.0012
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 254 43.9 0.0012
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 254 44.0 0.0014
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 254 44.1 0.0017
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 250 43.4 0.0018
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 249 43.3 0.0018
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 246 42.8 0.0021
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 243 42.5 0.0029
XP_016880718 (OMIM: 600838,601705) PREDICTED: fork ( 567) 245 42.9 0.0031
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 241 42.2 0.0032
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 236 41.5 0.0043
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 238 41.9 0.0046
XP_011519236 (OMIM: 602341) PREDICTED: forkhead bo ( 433) 236 41.6 0.0054
NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 236 41.7 0.0057
NP_068772 (OMIM: 602341) forkhead box protein M1 i ( 763) 240 42.3 0.0059
NP_001078940 (OMIM: 602628) forkhead box protein N ( 490) 236 41.7 0.0059
>>NP_005929 (OMIM: 300033) forkhead box protein O4 isofo (505 aa)
initn: 3425 init1: 3425 opt: 3425 Z-score: 2302.9 bits: 435.7 E(85289): 1.6e-121
Smith-Waterman score: 3425; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505)
10 20 30 40 50 60
pF1KB7 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE
430 440 450 460 470 480
490 500
pF1KB7 CDMDNIISDLMDEGEGLDFNFEPDP
:::::::::::::::::::::::::
NP_005 CDMDNIISDLMDEGEGLDFNFEPDP
490 500
>>NP_001164402 (OMIM: 300033) forkhead box protein O4 is (450 aa)
initn: 2640 init1: 2640 opt: 2640 Z-score: 1779.5 bits: 338.6 E(85289): 2.2e-92
Smith-Waterman score: 2925; 89.1% identity (89.1% similar) in 505 aa overlap (1-505:1-450)
10 20 30 40 50 60
pF1KB7 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEK---
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK
::::::::
NP_001 ----------------------------------------------------AIESAPEK
60
130 140 150 160 170 180
pF1KB7 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB7 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB7 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB7 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB7 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB7 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE
370 380 390 400 410 420
490 500
pF1KB7 CDMDNIISDLMDEGEGLDFNFEPDP
:::::::::::::::::::::::::
NP_001 CDMDNIISDLMDEGEGLDFNFEPDP
430 440 450
>>XP_011529259 (OMIM: 300033) PREDICTED: forkhead box pr (327 aa)
initn: 2185 init1: 2185 opt: 2185 Z-score: 1477.6 bits: 282.3 E(85289): 1.5e-75
Smith-Waterman score: 2185; 100.0% identity (100.0% similar) in 327 aa overlap (179-505:1-327)
150 160 170 180 190 200
pF1KB7 GWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGR
::::::::::::::::::::::::::::::
XP_011 MLNPEGGKSGKAPRRRAASMDSSSKLLRGR
10 20 30
210 220 230 240 250 260
pF1KB7 SKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVS
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB7 TRLSPLRPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRLSPLRPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFS
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB7 LQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCFSSSQALEALLTSDTPPPPADVLMTQVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCFSSSQALEALLTSDTPPPPADVLMTQVDP
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB7 ILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKA
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB7 LGTPVLTPPTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFEPDP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTPVLTPPTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFEPDP
280 290 300 310 320
>>NP_001278210 (OMIM: 611457) forkhead box protein O6 [H (559 aa)
initn: 1074 init1: 680 opt: 962 Z-score: 657.9 bits: 131.4 E(85289): 6.6e-30
Smith-Waterman score: 1086; 42.9% identity (60.2% similar) in 545 aa overlap (16-487:10-521)
10 20 30 40 50 60
pF1KB7 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT
.:.:::: :::::::::::::.:..:.. . :: : .
NP_001 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDE------DGALGAGV-A
10 20 30 40
70 80 90 100 110
pF1KB7 EGRSEPILLPSRLPEPAGGPQPGILGAVTGP-RKG-GSRRNAWGNQSYAELISQAIESAP
:: .: : :: .: : ::: .:: ::. .:::::::: :::.::..::::::
NP_001 EG-AEDCGPERRATAPAMAPAPP-LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 EKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWW
.:::::.:::.:::: :::::::::::::::::::::::::::..::.:.::.:::::::
NP_001 DKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWW
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 MLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAP---PEGATPTSP----
::::::::.::.:::::.:::...:.:: ..:: ::: : :: :. ..:..:
NP_001 MLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQ--LQAPERSPDDSSPSAPAPGP
170 180 190 200 210 220
240 250 260 270 280
pF1KB7 VGHFAKWSGSPCSRNREEADMWTTFR----PRSSSNASSVSTR-LSPLRPESEVLAEEIP
: :::..:: :. .. . :. :: : . : . . : : : : .. :
NP_001 VPAAAKWAASPASHASDDYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPS-P
230 240 250 260 270 280
290 300 310 320
pF1KB7 ASVSSYAGG--VP---PTLNE-----GLE----------LLDGLNLTSSHSLLSRSGLSG
::. : : : : : : : ::. :::: . .... .:.: .
NP_001 ASALSPALGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLDGAQ--DAYGPRARAGTPA
290 300 310 320 330 340
330 340 350 360
pF1KB7 -FSLQHPGVTG----------------PLHTYS---SSLFSPAEGPLSAGEGCFSSSQAL
:. . :. : :..: . .. : :: .:. : ::
NP_001 YFGGCKGGAYGGGGGFGPPAMGALRRLPMQTIQENKQASFVPAAAPFRPG--------AL
350 360 370 380 390
370 380 390 400 410
pF1KB7 EALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGL----------------PSSSKLAT
::: ::::: . :.:. :: : :.: :: : ::
NP_001 PALLP---PPPPA----PRPGPVLG-APGELALAGAAAAYPGKGAAPYAPPAPSRSALAH
400 410 420 430 440
420 430 440 450 460
pF1KB7 GVGLCPKPLEAPGPSSLVPTLSMIA---PPPVMASAPIPKALGTPVLTPPTEAASQDRMP
..: : :: : ..:.:. : :: . .: .. . : .:. ::.:
NP_001 PISLMTLPGEA-GAAGLAPSGHAAAFGGPPGGLLLDALPGPYAAAAAGP--LGAAPDRFP
450 460 470 480 490 500
470 480 490 500
pF1KB7 QDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFEPDP
::::::. .::::...::
NP_001 ADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG
510 520 530 540 550
>>NP_002006 (OMIM: 136533,268220) forkhead box protein O (655 aa)
initn: 1247 init1: 699 opt: 944 Z-score: 645.0 bits: 129.3 E(85289): 3.5e-29
Smith-Waterman score: 1010; 42.4% identity (62.5% similar) in 512 aa overlap (8-477:96-571)
10 20 30
pF1KB7 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPR
.:. ::: : :: :. .: : :
NP_002 VSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDF--QGPEAGCLHPAP-
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB7 PEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGS-
:. :: : :. .: :.:: : :::..:
NP_002 ------PQPPP---PG------------PLSQHPPVPPAAAGPLAG------QPRKSSSS
130 140 150
100 110 120 130 140 150
pF1KB7 RRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRH
::::::: :::.::..::::. ::::::.:::::::..::::::::::::::::::::::
NP_002 RRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRH
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB7 NLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKP
:::::::::.:.::.::::::::::::::::::.:::::::::..::. ..::.: :::
NP_002 NLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKA
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB7 SVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRP
: : . ::: :: ..:.:: .:: :.. .. : :.:::::.:::::..: ::::.
NP_002 S-LQSGQEGAGD-SPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMT
280 290 300 310 320 330
280 290 300 310 320
pF1KB7 ESEVLAE-EI-----PASVSSYAGGVPPTLN----EGLE-LLDGLNLTSSHSLLSRSGLS
:.. :.: .. : :....:. .: . :..: :::.::: :: . :. : :
NP_002 EQDDLGEGDVHSMVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQS
340 350 360 370 380 390
330 340 350 360
pF1KB7 G------------F-----SLQHPGVTGPLHTYSSSLFSP-AEGPLSAGEGCFSS----S
. : ::. :. . .::..: .:: . :... . :: :
NP_002 SPGTMMQQTPCYSFAPPNTSLNSPSPNYQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMS
400 410 420 430 440 450
370 380 390 400 410
pF1KB7 QA------LEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGG--LPSSSKLATGVGLC
: :. :::::.:: :. :: ::: ..: :. .:: . . ... . :
NP_002 QYNCAPGLLKELLTSDSPPH-NDI-MTPVDPGVAQ-PNSRVLGQNVMMGPNSVMSTYGSQ
460 470 480 490 500 510
420 430 440 450 460 470
pF1KB7 PKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMY
. . .::: . . .. . :.:....: : . .: . : .. :
NP_002 ASHNKMMNPSSHTHP-GHAQQTSAVNGRPLPHTVSTMPHTSGMNRLTQVKTPVQVPLPHP
520 530 540 550 560
480 490 500
pF1KB7 MENLECDMDNIISDLMDEGEGLDFNFEPDP
:.
NP_002 MQMSALGGYSSVSSCNGYGRMGLLHQEKLPSDLDGMFIERLDCDMESIIRNDLMDGDTLD
570 580 590 600 610 620
>>NP_963853 (OMIM: 602681) forkhead box protein O3 [Homo (673 aa)
initn: 1263 init1: 740 opt: 926 Z-score: 632.8 bits: 127.0 E(85289): 1.7e-28
Smith-Waterman score: 1057; 43.5% identity (61.9% similar) in 480 aa overlap (25-395:25-498)
10 20 30 40 50
pF1KB7 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEP----------PEV
::::::::::: :::. .:..: ::
NP_963 MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE
10 20 30 40 50 60
60
pF1KB7 EPD------------------------LGE--------KVHTEGRSEP------------
: : :: .: . : ..:
NP_963 EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB7 ----ILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRL
:: . : : :::: :. ::: .:::::::: :::.::..::::.:.:::
NP_963 GGTQALLQPQQPLPP--PQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRL
130 140 150 160 170
130 140 150 160 170 180
pF1KB7 TLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNP
::.:::::::: ::::::::::::::::::::::::::::.:..:.::.:::::::..::
NP_963 TLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINP
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 EGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSP
.::::::::::::.:::.:.: ..:..: ::: ..: . ::.: :: ....:: :::
NP_963 DGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKK-AALQTAPESADD-SP-SQLSKWPGSP
240 250 260 270 280 290
250 260 270 280 290
pF1KB7 CSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESE---VLAEEIPAS---VSSYAGGV
::. .: : :: :: :..::::.:: ::::. .: : .. : : :: :.
NP_963 TSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLS
300 310 320 330 340 350
300 310 320
pF1KB7 P----P---------------TLNEGL------ELLDGLNLTSSH-----SLLSRSGLSG
: : .::.:: .:::...: :. .:..::.
NP_963 PSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFP
360 370 380 390 400 410
330 340 350 360 370
pF1KB7 FSLQHPGVTGPLHTYSSSLFSPA------EGPLSAGE----GCFSS-----SQALEALLT
.. . :. .: ...:..:.:. ..:... . . ::: .:.:. :::
NP_963 YTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLT
420 430 440 450 460 470
380 390 400 410 420 430
pF1KB7 SDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAPGPSSLVPTL
::. .::.::: ::..::: :
NP_963 SDSLSH-SDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLL
480 490 500 510 520 530
>>NP_001446 (OMIM: 602681) forkhead box protein O3 [Homo (673 aa)
initn: 1263 init1: 740 opt: 926 Z-score: 632.8 bits: 127.0 E(85289): 1.7e-28
Smith-Waterman score: 1057; 43.5% identity (61.9% similar) in 480 aa overlap (25-395:25-498)
10 20 30 40 50
pF1KB7 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEP----------PEV
::::::::::: :::. .:..: ::
NP_001 MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE
10 20 30 40 50 60
60
pF1KB7 EPD------------------------LGE--------KVHTEGRSEP------------
: : :: .: . : ..:
NP_001 EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB7 ----ILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRL
:: . : : :::: :. ::: .:::::::: :::.::..::::.:.:::
NP_001 GGTQALLQPQQPLPP--PQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRL
130 140 150 160 170
130 140 150 160 170 180
pF1KB7 TLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNP
::.:::::::: ::::::::::::::::::::::::::::.:..:.::.:::::::..::
NP_001 TLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINP
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 EGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSP
.::::::::::::.:::.:.: ..:..: ::: ..: . ::.: :: ....:: :::
NP_001 DGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKK-AALQTAPESADD-SP-SQLSKWPGSP
240 250 260 270 280 290
250 260 270 280 290
pF1KB7 CSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESE---VLAEEIPAS---VSSYAGGV
::. .: : :: :: :..::::.:: ::::. .: : .. : : :: :.
NP_001 TSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLS
300 310 320 330 340 350
300 310 320
pF1KB7 P----P---------------TLNEGL------ELLDGLNLTSSH-----SLLSRSGLSG
: : .::.:: .:::...: :. .:..::.
NP_001 PSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFP
360 370 380 390 400 410
330 340 350 360 370
pF1KB7 FSLQHPGVTGPLHTYSSSLFSPA------EGPLSAGE----GCFSS-----SQALEALLT
.. . :. .: ...:..:.:. ..:... . . ::: .:.:. :::
NP_001 YTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLT
420 430 440 450 460 470
380 390 400 410 420 430
pF1KB7 SDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAPGPSSLVPTL
::. .::.::: ::..::: :
NP_001 SDSLSH-SDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLL
480 490 500 510 520 530
>>XP_011533310 (OMIM: 136533,268220) PREDICTED: forkhead (474 aa)
initn: 746 init1: 368 opt: 592 Z-score: 411.9 bits: 85.7 E(85289): 3.3e-16
Smith-Waterman score: 653; 39.7% identity (62.7% similar) in 370 aa overlap (150-477:27-390)
120 130 140 150 160 170
pF1KB7 KRLTLAQIYEWMVRTVPYFKDKGDSNSSAGW-KNSIRHNLSLHSKFIKVHNEATGKSSWW
: .::::::::::::::.:.::.:::::::
XP_011 MRSKHTANCLAFRCILAWPGGLAQNCWCQNSIRHNLSLHSKFIRVQNEGTGKSSWW
10 20 30 40 50
180 190 200 210 220 230
pF1KB7 MLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKW
:::::::::::.:::::::::..::. ..::.: ::: : : . ::: :: ..:.::
XP_011 MLNPEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKAS-LQSGQEGAGD-SPGSQFSKW
60 70 80 90 100 110
240 250 260 270 280 290
pF1KB7 SGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEE------IPASVSSY
.:: :.. .. : :.:::::.:::::..: ::::. :.. :.: : :....
XP_011 PASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKM
120 130 140 150 160 170
300 310 320 330
pF1KB7 AGGVPPTLN----EGLE-LLDGLNLTSSHSLLSRSGLSG------------F-----SLQ
:. .: . :..: :::.::: :: . :. : :. : ::.
XP_011 ASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLN
180 190 200 210 220 230
340 350 360 370
pF1KB7 HPGVTGPLHTYSSSLFSP-AEGPLSAGEGCFSS----SQA------LEALLTSDTPPPPA
:. . .::..: .:: . :... . :: :: :. :::::.::
XP_011 SPSPNYQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDSPPH-N
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB7 DVLMTQVDPILSQAPTLLLLGG--LPSSSKLATGVGLCPKPLEAPGPSSLVPTLSMIAPP
:. :: ::: ..: :. .:: . . ... . : . . .::: . .
XP_011 DI-MTPVDPGVAQ-PNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHP-GHAQQT
300 310 320 330 340 350
440 450 460 470 480 490
pF1KB7 PVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGL
.. . :.:....: : . .: . : .. : :.
XP_011 SAVNGRPLPHTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMG
360 370 380 390 400 410
500
pF1KB7 DFNFEPDP
XP_011 LLHQEKLPSDLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHS
420 430 440 450 460 470
>>XP_011533928 (OMIM: 602681) PREDICTED: forkhead box pr (506 aa)
initn: 699 init1: 350 opt: 527 Z-score: 368.1 bits: 77.7 E(85289): 9.2e-14
Smith-Waterman score: 628; 41.1% identity (65.3% similar) in 314 aa overlap (133-395:26-331)
110 120 130 140 150 160
pF1KB7 NQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHS
:: .. :. ::. .:::::::::::
XP_011 MRLPRSLGHGQVRRGGRGRRRGKGERTGVHLLDSPDSTE----ENSIRHNLSLHS
10 20 30 40 50
170 180 190 200 210 220
pF1KB7 KFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAP
.:..:.::.:::::::..::.::::::::::::.:::.:.: ..:..: ::: ..: .
XP_011 RFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKK-AALQTA
60 70 80 90 100 110
230 240 250 260 270
pF1KB7 PEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESE---
::.: :: ....:: ::: ::. .: : :: :: :..::::.:: ::::. .:
XP_011 PESADD-SP-SQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDE
120 130 140 150 160
280 290 300 310
pF1KB7 VLAEEIPAS---VSSYAGGVP----P---------------TLNEGL------ELLDGLN
: .. : : :: :. : : .::.:: .:::...
XP_011 VQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNIT
170 180 190 200 210 220
320 330 340 350
pF1KB7 LTSSH-----SLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPA------EGPLSAGE---
: :. .:..::. .. . :. .: ...:..:.:. ..:... .
XP_011 LPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENK
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB7 -GCFSS-----SQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATG
. ::: .:.:. :::::. .::.::: ::..::: :
XP_011 PATFSSMSHYGNQTLQDLLTSDSLSH-SDVMMTQSDPLMSQASTAVSAQNSRRNVMLRND
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB7 VGLCPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLD
XP_011 PMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQS
350 360 370 380 390 400
>>XP_005266924 (OMIM: 602681) PREDICTED: forkhead box pr (484 aa)
initn: 700 init1: 351 opt: 526 Z-score: 367.7 bits: 77.5 E(85289): 9.7e-14
Smith-Waterman score: 627; 41.7% identity (65.8% similar) in 307 aa overlap (141-395:7-309)
120 130 140 150 160
pF1KB7 SQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWK-NSIRHNLSLHSKFIKVHN
:: :... : :::::::::::.:..:.:
XP_005 MTVALQKGASGGGPCLKQNSIRHNLSLHSRFMRVQN
10 20 30
170 180 190 200 210 220
pF1KB7 EATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPT
:.:::::::..::.::::::::::::.:::.:.: ..:..: ::: ..: . ::.:
XP_005 EGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKK-AALQTAPESADD-
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB7 SPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESE---VLAEEIP
:: ....:: ::: ::. .: : :: :: :..::::.:: ::::. .: : .. :
XP_005 SP-SQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAP
100 110 120 130 140 150
290 300 310
pF1KB7 AS---VSSYAGGVP----P---------------TLNEGL------ELLDGLNLTSSH--
: :: :. : : .::.:: .:::...: :.
XP_005 LSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPS
160 170 180 190 200 210
320 330 340 350 360
pF1KB7 ---SLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPA------EGPLSAGE----GCFSS-
.:..::. .. . :. .: ...:..:.:. ..:... . . :::
XP_005 PTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSM
220 230 240 250 260 270
370 380 390 400 410
pF1KB7 ----SQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKP
.:.:. :::::. .::.::: ::..::: :
XP_005 SHYGNQTLQDLLTSDSLSH-SDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAA
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB7 LEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMEN
XP_005 QPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQ
340 350 360 370 380 390
505 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:14:12 2016 done: Fri Nov 4 22:14:14 2016
Total Scan time: 11.450 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]