Result of FASTA (omim) for
pF1KB7786
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7786, 512 aa
1>>>pF1KB7786 512 - 512 aa - 512 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6653+/-0.000348; mu= -7.4239+/- 0.022
mean_var=234.8643+/-49.134, 0's: 0 Z-trim(122.1): 146 B-trim: 743 in 2/60
Lambda= 0.083688
statistics sampled from 39539 (39696) to 39539 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.788), E-opt: 0.2 (0.465), width: 16
Scan time: 8.010
The best scores are: opt bits E(85289)
XP_006711273 (OMIM: 164873) PREDICTED: ETS translo ( 512) 3546 440.9 4.1e-123
NP_001138784 (OMIM: 164873) ETS translocation vari ( 512) 3546 440.9 4.1e-123
NP_005231 (OMIM: 164873) ETS translocation variant ( 143) 948 127.1 3.5e-29
NP_006485 (OMIM: 600775,611888) ETS domain-contain ( 548) 962 129.0 3.6e-29
NP_001299585 (OMIM: 600775,611888) ETS domain-cont ( 473) 536 77.5 9.7e-14
XP_016881958 (OMIM: 600775,611888) PREDICTED: ETS ( 473) 536 77.5 9.7e-14
XP_016881957 (OMIM: 600775,611888) PREDICTED: ETS ( 473) 536 77.5 9.7e-14
NP_001287964 (OMIM: 600775,611888) ETS domain-cont ( 473) 536 77.5 9.7e-14
NP_001295331 (OMIM: 600775,611888) ETS domain-cont ( 473) 536 77.5 9.7e-14
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 401 61.1 4.5e-09
NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 398 60.7 5.4e-09
XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410) 402 61.3 6.3e-09
NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 401 61.2 6.5e-09
XP_011541003 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 401 61.2 7e-09
XP_016872895 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 401 61.2 7e-09
XP_016872894 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 401 61.2 7e-09
NP_001161153 (OMIM: 193067) Friend leukemia integr ( 419) 401 61.2 7e-09
NP_002008 (OMIM: 193067) Friend leukemia integrati ( 452) 401 61.2 7.5e-09
NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 396 60.6 9.3e-09
NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 396 60.6 9.9e-09
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 396 60.6 1.1e-08
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 396 60.6 1.1e-08
NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 396 60.6 1.1e-08
XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 396 60.6 1.2e-08
NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 396 60.6 1.2e-08
NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 396 60.6 1.2e-08
NP_001230357 (OMIM: 165080) transcriptional regula ( 486) 396 60.6 1.2e-08
NP_001129626 (OMIM: 165080) transcriptional regula ( 486) 396 60.6 1.2e-08
NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 365 56.8 1.2e-07
XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 365 56.8 1.4e-07
XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 365 56.8 1.5e-07
NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 355 55.5 1.9e-07
XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 355 55.6 3.3e-07
XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 356 55.8 3.3e-07
NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 356 55.8 3.3e-07
XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 356 55.8 3.3e-07
NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 355 55.6 3.4e-07
XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 355 55.6 3.5e-07
XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 355 55.6 3.7e-07
NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 355 55.7 3.7e-07
XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 355 55.7 3.7e-07
XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 355 55.7 4e-07
NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 356 55.8 4.2e-07
NP_005220 (OMIM: 311040) ETS domain-containing pro ( 428) 348 54.8 6e-07
NP_001107595 (OMIM: 311040) ETS domain-containing ( 428) 348 54.8 6e-07
XP_016884828 (OMIM: 311040) PREDICTED: ETS domain- ( 428) 348 54.8 6e-07
NP_068567 (OMIM: 600246) ETS domain-containing pro ( 405) 346 54.5 6.8e-07
XP_016856069 (OMIM: 600246) PREDICTED: ETS domain- ( 413) 346 54.5 6.9e-07
XP_005245008 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 346 54.5 7.1e-07
NP_001964 (OMIM: 600246) ETS domain-containing pro ( 431) 346 54.5 7.1e-07
>>XP_006711273 (OMIM: 164873) PREDICTED: ETS translocati (512 aa)
initn: 3546 init1: 3546 opt: 3546 Z-score: 2331.2 bits: 440.9 E(85289): 4.1e-123
Smith-Waterman score: 3546; 100.0% identity (100.0% similar) in 512 aa overlap (1-512:1-512)
10 20 30 40 50 60
pF1KB7 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTNDVQPGRFSASSLTASGQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTNDVQPGRFSASSLTASGQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SSNGTDRKTELSELEDGSAADWRRGVDPVSSRNAIGGGGIGHQKRKPDIMLPLFARPGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSNGTDRKTELSELEDGSAADWRRGVDPVSSRNAIGGGGIGHQKRKPDIMLPLFARPGMY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 PDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSSSCFSFNPEEMKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSSSCFSFNPEEMKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YLHSQACSVFNYHLSPRTFPRYPGLMVPPLQCQMHPEESTQFSIKLQPPPVGRKNRERVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLHSQACSVFNYHLSPRTFPRYPGLMVPPLQCQMHPEESTQFSIKLQPPPVGRKNRERVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SSEESAPVTTPTMASIPPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSEESAPVTTPTMASIPPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRW
430 440 450 460 470 480
490 500 510
pF1KB7 NDDPEARELSKSGKFLWNGSGPQGLATAAADA
::::::::::::::::::::::::::::::::
XP_006 NDDPEARELSKSGKFLWNGSGPQGLATAAADA
490 500 510
>>NP_001138784 (OMIM: 164873) ETS translocation variant (512 aa)
initn: 3546 init1: 3546 opt: 3546 Z-score: 2331.2 bits: 440.9 E(85289): 4.1e-123
Smith-Waterman score: 3546; 100.0% identity (100.0% similar) in 512 aa overlap (1-512:1-512)
10 20 30 40 50 60
pF1KB7 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTNDVQPGRFSASSLTASGQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTNDVQPGRFSASSLTASGQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SSNGTDRKTELSELEDGSAADWRRGVDPVSSRNAIGGGGIGHQKRKPDIMLPLFARPGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSNGTDRKTELSELEDGSAADWRRGVDPVSSRNAIGGGGIGHQKRKPDIMLPLFARPGMY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 PDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSSSCFSFNPEEMKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSSSCFSFNPEEMKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YLHSQACSVFNYHLSPRTFPRYPGLMVPPLQCQMHPEESTQFSIKLQPPPVGRKNRERVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLHSQACSVFNYHLSPRTFPRYPGLMVPPLQCQMHPEESTQFSIKLQPPPVGRKNRERVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 SSEESAPVTTPTMASIPPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSEESAPVTTPTMASIPPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 TIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRW
430 440 450 460 470 480
490 500 510
pF1KB7 NDDPEARELSKSGKFLWNGSGPQGLATAAADA
::::::::::::::::::::::::::::::::
NP_001 NDDPEARELSKSGKFLWNGSGPQGLATAAADA
490 500 510
>>NP_005231 (OMIM: 164873) ETS translocation variant 3 i (143 aa)
initn: 948 init1: 948 opt: 948 Z-score: 644.9 bits: 127.1 E(85289): 3.5e-29
Smith-Waterman score: 948; 98.5% identity (99.3% similar) in 136 aa overlap (1-136:1-136)
10 20 30 40 50 60
pF1KB7 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTNDVQPGRFSASSLTASGQE
:::::::::::::: .
NP_005 VMPNYPFINIRSSGKIQTLLVGN
130 140
>>NP_006485 (OMIM: 600775,611888) ETS domain-containing (548 aa)
initn: 1060 init1: 480 opt: 962 Z-score: 644.6 bits: 129.0 E(85289): 3.6e-29
Smith-Waterman score: 1324; 45.6% identity (62.0% similar) in 553 aa overlap (10-504:2-502)
10 20 30 40 50 60
pF1KB7 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE
: . :. ::::::: :::::::::::::::::::.:::.. ::::: :.
NP_006 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQ-GD
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_006 YGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 VMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPPL---DTHSPTNDVQPGRFSASSLTA
:. :::::.. ..:.:::::::::...:.:.::: .. :::.: : : : ..
NP_006 VLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTED--PRSPPACSSSS
120 130 140 150 160
180 190 200 210 220 230
pF1KB7 SGQESSNGTDR--KTELSELEDGSAA-DWRRGVDPVSSRNAIGGGGIGHQKRKPDIMLP-
:. :. . : . .:. ::.. . : :: .: : .: . : ::
NP_006 SSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDP-RARPP-GPPDLGAFRGPPLARLPH
170 180 190 200 210 220
240 250 260 270 280
pF1KB7 ------LFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFT
.. :: :.: ::: :::. : :..: .:::: .::: ..:.::: :::.
NP_006 DPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMY
230 240 250 260 270 280
290 300 310 320 330
pF1KB7 SS-----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP----PLQ
: : :::.::.::.::.... ::.:::::::.: .::::.:: : .
NP_006 PSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDK
290 300 310 320 330 340
340 350 360 370
pF1KB7 CQ---MHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPVTTPTMA
: : :: :. :..::::::.::..: :.. .: . . .
NP_006 CPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAG
350 360 370 380 390 400
380 390 400 410 420
pF1KB7 SI------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKGTI
.. ::.::::: :: . : . : . ..:. :: : .
NP_006 GLAEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------EEDGEV
410 420 430 440 450
430 440 450 460 470 480
pF1KB7 FARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRWND
: : ::: : .: .::. :.: . :: :::.::::..
NP_006 FKTPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRFKRRWSE
460 470 480 490
490 500 510
pF1KB7 DPEARELSKSGKFLWNGSGPQGLATAAADA
: . : .:.:: :
NP_006 DCR----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQ
500 510 520 530 540
>>NP_001299585 (OMIM: 600775,611888) ETS domain-containi (473 aa)
initn: 874 init1: 294 opt: 536 Z-score: 367.7 bits: 77.5 E(85289): 9.7e-14
Smith-Waterman score: 898; 40.2% identity (57.9% similar) in 478 aa overlap (85-504:1-427)
60 70 80 90 100 110
pF1KB7 AWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
NP_001 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
120 130 140 150 160 170
pF1KB7 FNFNKLVMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPPL---DTHSPTNDVQPGRFS
:::::::. :::::.. ..:.:::::::::...:.:.::: .. :::.: :
NP_001 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTED--PRSPP
40 50 60 70 80
180 190 200 210 220
pF1KB7 ASSLTASGQESSNGTDR--KTELSELEDGSAA-DWRRGVDPVSSRNAIGGGGIGHQKRKP
: : ..:. :. . : . .:. ::.. . : :: .: : .: . :
NP_001 ACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDP-RARPP-GPPDLGAFRGPP
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB7 DIMLP-------LFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSP
:: .. :: :.: ::: :::. : :..: .:::: .::: ..:.:::
NP_001 LARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSP
150 160 170 180 190 200
290 300 310 320
pF1KB7 GLSPFTSS-----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP-
:::. : : :::.::.::.::.... ::.:::::::.: .::::.::
NP_001 TLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQ
210 220 230 240 250 260
330 340 350 360
pF1KB7 ---PLQCQ---MHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPV
: .: : :: :. :..::::::.::..: :.. .:
NP_001 PQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADK
270 280 290 300 310 320
370 380 390 400 410
pF1KB7 TTPTMASI------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIE
. . ... ::.::::: :: . : . : . ..:.
NP_001 SGGSAGGLAEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------
330 340 350 360 370
420 430 440 450 460 470
pF1KB7 EEKGTIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRL
:: : .: : ::: : .: .::. :.: . :: :::.
NP_001 EEDGEVFKTPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRF
380 390 400
480 490 500 510
pF1KB7 KRRWNDDPEARELSKSGKFLWNGSGPQGLATAAADA
::::..: . : .:.:: :
NP_001 KRRWSEDCR----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDL
410 420 430 440 450
>>XP_016881958 (OMIM: 600775,611888) PREDICTED: ETS doma (473 aa)
initn: 874 init1: 294 opt: 536 Z-score: 367.7 bits: 77.5 E(85289): 9.7e-14
Smith-Waterman score: 898; 40.2% identity (57.9% similar) in 478 aa overlap (85-504:1-427)
60 70 80 90 100 110
pF1KB7 AWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
XP_016 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
120 130 140 150 160 170
pF1KB7 FNFNKLVMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPPL---DTHSPTNDVQPGRFS
:::::::. :::::.. ..:.:::::::::...:.:.::: .. :::.: :
XP_016 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTED--PRSPP
40 50 60 70 80
180 190 200 210 220
pF1KB7 ASSLTASGQESSNGTDR--KTELSELEDGSAA-DWRRGVDPVSSRNAIGGGGIGHQKRKP
: : ..:. :. . : . .:. ::.. . : :: .: : .: . :
XP_016 ACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDP-RARPP-GPPDLGAFRGPP
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB7 DIMLP-------LFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSP
:: .. :: :.: ::: :::. : :..: .:::: .::: ..:.:::
XP_016 LARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSP
150 160 170 180 190 200
290 300 310 320
pF1KB7 GLSPFTSS-----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP-
:::. : : :::.::.::.::.... ::.:::::::.: .::::.::
XP_016 TLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQ
210 220 230 240 250 260
330 340 350 360
pF1KB7 ---PLQCQ---MHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPV
: .: : :: :. :..::::::.::..: :.. .:
XP_016 PQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADK
270 280 290 300 310 320
370 380 390 400 410
pF1KB7 TTPTMASI------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIE
. . ... ::.::::: :: . : . : . ..:.
XP_016 SGGSAGGLAEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------
330 340 350 360 370
420 430 440 450 460 470
pF1KB7 EEKGTIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRL
:: : .: : ::: : .: .::. :.: . :: :::.
XP_016 EEDGEVFKTPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRF
380 390 400
480 490 500 510
pF1KB7 KRRWNDDPEARELSKSGKFLWNGSGPQGLATAAADA
::::..: . : .:.:: :
XP_016 KRRWSEDCR----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDL
410 420 430 440 450
>>XP_016881957 (OMIM: 600775,611888) PREDICTED: ETS doma (473 aa)
initn: 874 init1: 294 opt: 536 Z-score: 367.7 bits: 77.5 E(85289): 9.7e-14
Smith-Waterman score: 898; 40.2% identity (57.9% similar) in 478 aa overlap (85-504:1-427)
60 70 80 90 100 110
pF1KB7 AWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
XP_016 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
120 130 140 150 160 170
pF1KB7 FNFNKLVMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPPL---DTHSPTNDVQPGRFS
:::::::. :::::.. ..:.:::::::::...:.:.::: .. :::.: :
XP_016 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTED--PRSPP
40 50 60 70 80
180 190 200 210 220
pF1KB7 ASSLTASGQESSNGTDR--KTELSELEDGSAA-DWRRGVDPVSSRNAIGGGGIGHQKRKP
: : ..:. :. . : . .:. ::.. . : :: .: : .: . :
XP_016 ACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDP-RARPP-GPPDLGAFRGPP
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB7 DIMLP-------LFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSP
:: .. :: :.: ::: :::. : :..: .:::: .::: ..:.:::
XP_016 LARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSP
150 160 170 180 190 200
290 300 310 320
pF1KB7 GLSPFTSS-----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP-
:::. : : :::.::.::.::.... ::.:::::::.: .::::.::
XP_016 TLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQ
210 220 230 240 250 260
330 340 350 360
pF1KB7 ---PLQCQ---MHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPV
: .: : :: :. :..::::::.::..: :.. .:
XP_016 PQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADK
270 280 290 300 310 320
370 380 390 400 410
pF1KB7 TTPTMASI------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIE
. . ... ::.::::: :: . : . : . ..:.
XP_016 SGGSAGGLAEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------
330 340 350 360 370
420 430 440 450 460 470
pF1KB7 EEKGTIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRL
:: : .: : ::: : .: .::. :.: . :: :::.
XP_016 EEDGEVFKTPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRF
380 390 400
480 490 500 510
pF1KB7 KRRWNDDPEARELSKSGKFLWNGSGPQGLATAAADA
::::..: . : .:.:: :
XP_016 KRRWSEDCR----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDL
410 420 430 440 450
>>NP_001287964 (OMIM: 600775,611888) ETS domain-containi (473 aa)
initn: 874 init1: 294 opt: 536 Z-score: 367.7 bits: 77.5 E(85289): 9.7e-14
Smith-Waterman score: 898; 40.2% identity (57.9% similar) in 478 aa overlap (85-504:1-427)
60 70 80 90 100 110
pF1KB7 AWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
NP_001 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
120 130 140 150 160 170
pF1KB7 FNFNKLVMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPPL---DTHSPTNDVQPGRFS
:::::::. :::::.. ..:.:::::::::...:.:.::: .. :::.: :
NP_001 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTED--PRSPP
40 50 60 70 80
180 190 200 210 220
pF1KB7 ASSLTASGQESSNGTDR--KTELSELEDGSAA-DWRRGVDPVSSRNAIGGGGIGHQKRKP
: : ..:. :. . : . .:. ::.. . : :: .: : .: . :
NP_001 ACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDP-RARPP-GPPDLGAFRGPP
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB7 DIMLP-------LFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSP
:: .. :: :.: ::: :::. : :..: .:::: .::: ..:.:::
NP_001 LARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSP
150 160 170 180 190 200
290 300 310 320
pF1KB7 GLSPFTSS-----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP-
:::. : : :::.::.::.::.... ::.:::::::.: .::::.::
NP_001 TLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQ
210 220 230 240 250 260
330 340 350 360
pF1KB7 ---PLQCQ---MHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPV
: .: : :: :. :..::::::.::..: :.. .:
NP_001 PQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADK
270 280 290 300 310 320
370 380 390 400 410
pF1KB7 TTPTMASI------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIE
. . ... ::.::::: :: . : . : . ..:.
NP_001 SGGSAGGLAEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------
330 340 350 360 370
420 430 440 450 460 470
pF1KB7 EEKGTIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRL
:: : .: : ::: : .: .::. :.: . :: :::.
NP_001 EEDGEVFKTPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRF
380 390 400
480 490 500 510
pF1KB7 KRRWNDDPEARELSKSGKFLWNGSGPQGLATAAADA
::::..: . : .:.:: :
NP_001 KRRWSEDCR----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDL
410 420 430 440 450
>>NP_001295331 (OMIM: 600775,611888) ETS domain-containi (473 aa)
initn: 874 init1: 294 opt: 536 Z-score: 367.7 bits: 77.5 E(85289): 9.7e-14
Smith-Waterman score: 898; 40.2% identity (57.9% similar) in 478 aa overlap (85-504:1-427)
60 70 80 90 100 110
pF1KB7 AWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK
::::::::::::::::::::::::::::::
NP_001 MNYDKLSRALRYYYNKRILHKTKGKRFTYK
10 20 30
120 130 140 150 160 170
pF1KB7 FNFNKLVMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPPL---DTHSPTNDVQPGRFS
:::::::. :::::.. ..:.:::::::::...:.:.::: .. :::.: :
NP_001 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTED--PRSPP
40 50 60 70 80
180 190 200 210 220
pF1KB7 ASSLTASGQESSNGTDR--KTELSELEDGSAA-DWRRGVDPVSSRNAIGGGGIGHQKRKP
: : ..:. :. . : . .:. ::.. . : :: .: : .: . :
NP_001 ACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDP-RARPP-GPPDLGAFRGPP
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB7 DIMLP-------LFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSP
:: .. :: :.: ::: :::. : :..: .:::: .::: ..:.:::
NP_001 LARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSP
150 160 170 180 190 200
290 300 310 320
pF1KB7 GLSPFTSS-----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP-
:::. : : :::.::.::.::.... ::.:::::::.: .::::.::
NP_001 TLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQ
210 220 230 240 250 260
330 340 350 360
pF1KB7 ---PLQCQ---MHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPV
: .: : :: :. :..::::::.::..: :.. .:
NP_001 PQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADK
270 280 290 300 310 320
370 380 390 400 410
pF1KB7 TTPTMASI------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIE
. . ... ::.::::: :: . : . : . ..:.
NP_001 SGGSAGGLAEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------
330 340 350 360 370
420 430 440 450 460 470
pF1KB7 EEKGTIFARPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRL
:: : .: : ::: : .: .::. :.: . :: :::.
NP_001 EEDGEVFKTPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRF
380 390 400
480 490 500 510
pF1KB7 KRRWNDDPEARELSKSGKFLWNGSGPQGLATAAADA
::::..: . : .:.:: :
NP_001 KRRWSEDCR----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDL
410 420 430 440 450
>>NP_001257941 (OMIM: 193067) Friend leukemia integratio (259 aa)
initn: 451 init1: 288 opt: 401 Z-score: 283.8 bits: 61.1 E(85289): 4.5e-09
Smith-Waterman score: 401; 48.5% identity (68.7% similar) in 134 aa overlap (28-161:81-197)
10 20 30 40 50
pF1KB7 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQ
..::: :::::.:.::::. :.:.
NP_001 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
60 70 80 90 100 110
60 70 80 90 100 110
pF1KB7 QGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNF
: ::: . ::::::: ::.:: ::.::::::::::::::.: :. :..:::..:::.:
NP_001 -GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDF
120 130 140 150 160
120 130 140 150 160 170
pF1KB7 NKLVMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTNDVQPGRFSASSLTAS
. :.. :. : :: :: ...: .. :.
NP_001 H---------------GIA-QALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPS
170 180 190 200 210
180 190 200 210 220 230
pF1KB7 GQESSNGTDRKTELSELEDGSAADWRRGVDPVSSRNAIGGGGIGHQKRKPDIMLPLFARP
NP_001 SMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
220 230 240 250
512 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:20:33 2016 done: Sat Nov 5 16:20:34 2016
Total Scan time: 8.010 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]