FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7791, 459 aa 1>>>pF1KB7791 459 - 459 aa - 459 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7785+/-0.000373; mu= 14.0281+/- 0.023 mean_var=243.2118+/-48.832, 0's: 0 Z-trim(121.4): 1982 B-trim: 124 in 1/57 Lambda= 0.082240 statistics sampled from 35584 (37840) to 35584 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.444), width: 16 Scan time: 11.070 The best scores are: opt bits E(85289) NP_004211 (OMIM: 608387) zinc finger protein 213 [ ( 459) 3256 399.4 1e-110 NP_001128127 (OMIM: 608387) zinc finger protein 21 ( 459) 3256 399.4 1e-110 XP_011520954 (OMIM: 608387) PREDICTED: zinc finger ( 285) 1687 212.9 8.8e-55 XP_005249152 (OMIM: 611643) PREDICTED: zinc finger ( 545) 971 128.4 4.7e-29 NP_061983 (OMIM: 611643) zinc finger protein with ( 545) 971 128.4 4.7e-29 NP_077819 (OMIM: 612791) zinc finger protein with ( 538) 960 127.1 1.2e-28 XP_006715278 (OMIM: 612791) PREDICTED: zinc finger ( 538) 960 127.1 1.2e-28 NP_001229823 (OMIM: 612791) zinc finger protein wi ( 538) 960 127.1 1.2e-28 NP_001308045 (OMIM: 165260) zinc finger and SCAN d ( 491) 955 126.4 1.7e-28 NP_862829 (OMIM: 165260) zinc finger and SCAN doma ( 491) 955 126.4 1.7e-28 XP_011525219 (OMIM: 165260) PREDICTED: zinc finger ( 491) 955 126.4 1.7e-28 XP_006723255 (OMIM: 165260) PREDICTED: zinc finger ( 491) 955 126.4 1.7e-28 XP_006720896 (OMIM: 604191) PREDICTED: zinc finger ( 598) 861 115.4 4.2e-25 XP_006718374 (OMIM: 605016) PREDICTED: zinc finger ( 517) 652 90.5 1.1e-17 NP_037382 (OMIM: 605016) zinc finger protein 215 [ ( 517) 652 90.5 1.1e-17 XP_011517301 (OMIM: 603132) PREDICTED: zinc finger ( 575) 652 90.6 1.2e-17 XP_006717343 (OMIM: 603132) PREDICTED: zinc finger ( 584) 652 90.6 1.2e-17 XP_011517300 (OMIM: 603132) PREDICTED: zinc finger ( 584) 652 90.6 1.2e-17 XP_016870610 (OMIM: 603132) PREDICTED: zinc finger ( 584) 652 90.6 1.2e-17 NP_932094 (OMIM: 603132) zinc finger protein 189 i ( 584) 652 90.6 1.2e-17 XP_006717344 (OMIM: 603132) PREDICTED: zinc finger ( 584) 652 90.6 1.2e-17 NP_001265161 (OMIM: 603132) zinc finger protein 18 ( 611) 652 90.6 1.2e-17 NP_001265160 (OMIM: 603132) zinc finger protein 18 ( 612) 652 90.6 1.2e-17 NP_003443 (OMIM: 603132) zinc finger protein 189 i ( 626) 652 90.7 1.3e-17 XP_016882854 (OMIM: 615580) PREDICTED: zinc finger ( 566) 650 90.4 1.4e-17 XP_011525696 (OMIM: 615580) PREDICTED: zinc finger ( 566) 650 90.4 1.4e-17 XP_005259380 (OMIM: 615580) PREDICTED: zinc finger ( 566) 650 90.4 1.4e-17 XP_016882852 (OMIM: 615580) PREDICTED: zinc finger ( 618) 650 90.4 1.5e-17 XP_016882851 (OMIM: 615580) PREDICTED: zinc finger ( 618) 650 90.4 1.5e-17 XP_016882853 (OMIM: 615580) PREDICTED: zinc finger ( 618) 650 90.4 1.5e-17 NP_115799 (OMIM: 615580) zinc finger protein 528 [ ( 628) 650 90.4 1.5e-17 XP_016882850 (OMIM: 615580) PREDICTED: zinc finger ( 702) 650 90.5 1.6e-17 XP_016882849 (OMIM: 615580) PREDICTED: zinc finger ( 702) 650 90.5 1.6e-17 XP_011525694 (OMIM: 615580) PREDICTED: zinc finger ( 712) 650 90.5 1.6e-17 XP_006723481 (OMIM: 615580) PREDICTED: zinc finger ( 712) 650 90.5 1.6e-17 XP_016882742 (OMIM: 606740) PREDICTED: zinc finger ( 349) 645 89.4 1.6e-17 NP_001275691 (OMIM: 606740) zinc finger protein 18 ( 349) 645 89.4 1.6e-17 XP_016882743 (OMIM: 606740) PREDICTED: zinc finger ( 349) 645 89.4 1.6e-17 XP_016882741 (OMIM: 606740) PREDICTED: zinc finger ( 349) 645 89.4 1.6e-17 XP_016882740 (OMIM: 606740) PREDICTED: zinc finger ( 349) 645 89.4 1.6e-17 NP_001275689 (OMIM: 606740) zinc finger protein 18 ( 349) 645 89.4 1.6e-17 XP_016882744 (OMIM: 606740) PREDICTED: zinc finger ( 349) 645 89.4 1.6e-17 XP_016882745 (OMIM: 606740) PREDICTED: zinc finger ( 349) 645 89.4 1.6e-17 XP_016882739 (OMIM: 606740) PREDICTED: zinc finger ( 349) 645 89.4 1.6e-17 NP_001275690 (OMIM: 606740) zinc finger protein 18 ( 349) 645 89.4 1.6e-17 XP_005272399 (OMIM: 601262) PREDICTED: zinc finger ( 542) 647 90.0 1.8e-17 XP_011515600 (OMIM: 601262) PREDICTED: zinc finger ( 682) 647 90.1 2e-17 NP_001025147 (OMIM: 601262) zinc finger protein 16 ( 682) 647 90.1 2e-17 XP_005272398 (OMIM: 601262) PREDICTED: zinc finger ( 682) 647 90.1 2e-17 NP_008889 (OMIM: 601262) zinc finger protein 16 [H ( 682) 647 90.1 2e-17 >>NP_004211 (OMIM: 608387) zinc finger protein 213 [Homo (459 aa) initn: 3256 init1: 3256 opt: 3256 Z-score: 2108.5 bits: 399.4 E(85289): 1e-110 Smith-Waterman score: 3256; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459) 10 20 30 40 50 60 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSAQPPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSAQPPAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GFGLKGQSEKSLLQEMVPVVPGQTGSDVTVSWSPEEAEAWESENRPRAALGPVVGARRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GFGLKGQSEKSLLQEMVPVVPGQTGSDVTVSWSPEEAEAWESENRPRAALGPVVGARRGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTHTGEKPHKCPECDKSFRSSSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTHTGEKPHKCPECDKSFRSSSDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 VRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFGCSDCGKSFSLRSYLLDHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFGCSDCGKSFSLRSYLLDHR 370 380 390 400 410 420 430 440 450 pF1KB7 RVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKMAQPVG ::::::::::::::::::::::::::::::::::::::: NP_004 RVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKMAQPVG 430 440 450 >>NP_001128127 (OMIM: 608387) zinc finger protein 213 [H (459 aa) initn: 3256 init1: 3256 opt: 3256 Z-score: 2108.5 bits: 399.4 E(85289): 1e-110 Smith-Waterman score: 3256; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459) 10 20 30 40 50 60 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSAQPPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSAQPPAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GFGLKGQSEKSLLQEMVPVVPGQTGSDVTVSWSPEEAEAWESENRPRAALGPVVGARRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFGLKGQSEKSLLQEMVPVVPGQTGSDVTVSWSPEEAEAWESENRPRAALGPVVGARRGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTHTGEKPHKCPECDKSFRSSSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTHTGEKPHKCPECDKSFRSSSDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 VRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFGCSDCGKSFSLRSYLLDHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFGCSDCGKSFSLRSYLLDHR 370 380 390 400 410 420 430 440 450 pF1KB7 RVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKMAQPVG ::::::::::::::::::::::::::::::::::::::: NP_001 RVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKMAQPVG 430 440 450 >>XP_011520954 (OMIM: 608387) PREDICTED: zinc finger pro (285 aa) initn: 1687 init1: 1687 opt: 1687 Z-score: 1104.5 bits: 212.9 E(85289): 8.8e-55 Smith-Waterman score: 1687; 99.2% identity (100.0% similar) in 242 aa overlap (1-242:1-242) 10 20 30 40 50 60 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSAQPPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSAQPPAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GFGLKGQSEKSLLQEMVPVVPGQTGSDVTVSWSPEEAEAWESENRPRAALGPVVGARRGR .. XP_011 ALAPEPRGTEEVASFPLQVLGSKAKVRSPCCRRWCRWCQARQAAT 250 260 270 280 >>XP_005249152 (OMIM: 611643) PREDICTED: zinc finger pro (545 aa) initn: 1830 init1: 574 opt: 971 Z-score: 642.6 bits: 128.4 E(85289): 4.7e-29 Smith-Waterman score: 1070; 39.9% identity (63.1% similar) in 471 aa overlap (3-451:9-454) 10 20 30 40 50 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVED---SSWEQE-SAQHEDGRDSEACRQRFRQ : :.::. . ::: :::: :. : : .: : ::::: XP_005 MAREPRKNAALDAQSAE--DQTGLLTVKVEKEEASALTAEVRAPCSPARGPERSRQRFRG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 FCYGDVHGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHP : : .. ::.::.:.: ::: .::.::...:::::::::::::::.:::..:.::::::: XP_005 FRYPEAAGPREALSRLRELCGQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHP 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 GSGEEAVALVEDLQKQ--------PVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARR ::::.:.:.: :..: :: :.. . . .:::.. : . . XP_005 ESGEEVVVLLEYLERQLDEPAPQVPVGDQGQELLCCKMALLTQTQGSQSSQCQPMKALFK 120 130 140 150 160 170 170 180 190 200 210 pF1KB7 RPSV-PQEQHSHSAQPPALLKEG--RPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTL . :. : :.. : :.: . : : . . .. : .: . . :. . .. : : XP_005 HESLGSQPLHDRVLQVPGLAQGGCCREDAMVASRLTPGSQGLLKMEDVALTLT-PGWTQL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 DPAQRDLFWDIKRENSRNTTLGFGLKGQSEKSLLQEMVPV--VPGQTGSDVT-----VSW : .: .:. : :.:: ... ...: . :... ... :: .: . . . .. XP_005 DSSQVNLYRDEKQEN-HSSLVSLGGEIQTKS---RDLPPVKKLPEKEHGKICHLREDIAQ 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 SPEEAEAWESENRPRAALGPVVGARRGRPPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDL : .::: :.:.: . ..:.:: : : .::: : .: : XP_005 IPTHAEAGEQEGRLQRKQKNAIGSRR------------------HYCHECGKSFAQSSGL 300 310 320 330 340 350 360 370 380 390 pF1KB7 ARHQRTHTGEKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQ ..:.: ::::::..: .: :.: .:: :: :: :::::::. : :::: ::.:. : :: XP_005 TKHRRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQ 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB7 RIHTGEKPFGCSDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQSLHA : ::::::. :.::::.:: ::.:...::::.:. :. : :.:.. .::. :: .: XP_005 RTHTGEKPYECDDCGKTFSQSCSLLEHHKIHTGEKPYQCNMCGKAFRRNSHLLRHQRIHG 400 410 420 430 440 450 pF1KB7 KMAQPVG XP_005 DKNVQNPEHGESWESQGRTESQWENTEAPVSYKCNECERSFTRNRSLIEHQKIHTGEKPY 460 470 480 490 500 510 >>NP_061983 (OMIM: 611643) zinc finger protein with KRAB (545 aa) initn: 1830 init1: 574 opt: 971 Z-score: 642.6 bits: 128.4 E(85289): 4.7e-29 Smith-Waterman score: 1070; 39.9% identity (63.1% similar) in 471 aa overlap (3-451:9-454) 10 20 30 40 50 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVED---SSWEQE-SAQHEDGRDSEACRQRFRQ : :.::. . ::: :::: :. : : .: : ::::: NP_061 MAREPRKNAALDAQSAE--DQTGLLTVKVEKEEASALTAEVRAPCSPARGPERSRQRFRG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 FCYGDVHGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHP : : .. ::.::.:.: ::: .::.::...:::::::::::::::.:::..:.::::::: NP_061 FRYPEAAGPREALSRLRELCGQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHP 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 GSGEEAVALVEDLQKQ--------PVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARR ::::.:.:.: :..: :: :.. . . .:::.. : . . NP_061 ESGEEVVVLLEYLERQLDEPAPQVPVGDQGQELLCCKMALLTQTQGSQSSQCQPMKALFK 120 130 140 150 160 170 170 180 190 200 210 pF1KB7 RPSV-PQEQHSHSAQPPALLKEG--RPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTL . :. : :.. : :.: . : : . . .. : .: . . :. . .. : : NP_061 HESLGSQPLHDRVLQVPGLAQGGCCREDAMVASRLTPGSQGLLKMEDVALTLT-PGWTQL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 DPAQRDLFWDIKRENSRNTTLGFGLKGQSEKSLLQEMVPV--VPGQTGSDVT-----VSW : .: .:. : :.:: ... ...: . :... ... :: .: . . . .. NP_061 DSSQVNLYRDEKQEN-HSSLVSLGGEIQTKS---RDLPPVKKLPEKEHGKICHLREDIAQ 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 SPEEAEAWESENRPRAALGPVVGARRGRPPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDL : .::: :.:.: . ..:.:: : : .::: : .: : NP_061 IPTHAEAGEQEGRLQRKQKNAIGSRR------------------HYCHECGKSFAQSSGL 300 310 320 330 340 350 360 370 380 390 pF1KB7 ARHQRTHTGEKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQ ..:.: ::::::..: .: :.: .:: :: :: :::::::. : :::: ::.:. : :: NP_061 TKHRRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQ 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB7 RIHTGEKPFGCSDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQSLHA : ::::::. :.::::.:: ::.:...::::.:. :. : :.:.. .::. :: .: NP_061 RTHTGEKPYECDDCGKTFSQSCSLLEHHKIHTGEKPYQCNMCGKAFRRNSHLLRHQRIHG 400 410 420 430 440 450 pF1KB7 KMAQPVG NP_061 DKNVQNPEHGESWESQGRTESQWENTEAPVSYKCNECERSFTRNRSLIEHQKIHTGEKPY 460 470 480 490 500 510 >>NP_077819 (OMIM: 612791) zinc finger protein with KRAB (538 aa) initn: 2033 init1: 584 opt: 960 Z-score: 635.6 bits: 127.1 E(85289): 1.2e-28 Smith-Waterman score: 1011; 38.7% identity (65.3% similar) in 447 aa overlap (18-451:22-448) 10 20 30 40 50 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDV ::..:::. :. . ::. :.::: : : .. NP_077 MARELSESTALDAQSTEDQMELLVIKVEE---EEAGFPSSPDLGSEGSRERFRGFRYPEA 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 HGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEA ::.::.:.: ::: .::.::...:::::::::::::::.:::..:.::::::: ::::. NP_077 AGPREALSRLRELCRQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEV 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 VALVEDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGAR--------RRPSV-P :.:.: :..: . : .... . . : : . ... .. :: NP_077 VVLLEYLERQLDEPAPQVSGVDQGQELLCCKMALLTPAPGSQSSQFQLMKALLKHESVGS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 QEQHSHSAQPPALLKEG--RPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRD : ... : :.: . : : ... . .. .: . . :. . .. :: : .: . NP_077 QPLQDRVLQVPVLAHGGCCREDKVVASRLTPESQGLLKVEDVALTLT-PEWTQQDSSQGN 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 LFWDIKRENSRNTTLGFGLKGQSEKSLLQEMVPV--VPGQTGSDVTVSWSPEEAEAWESE : : :.:: ... ...: . :... ... :. .: . . .. . :. NP_077 LCRDEKQEN-HGSLVSLGDEKQTKS---RDLPPAEELPEKEHGKISCHLREDIAQI---- 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 NRPRAALGPVVGARRGRPPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTHTGEK : : . : ..:: .:.: .. .. . : : .::: : .: :..:.: ::::: NP_077 --PTCAEA---GEQEGR--LQRKQ-KNATGGRRHICHECGKSFAQSSGLSKHRRIHTGEK 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB7 PHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFGC :..: :: :.: .:: :: :: :::::::. : ::::.::.:. : ::: ::::::. : NP_077 PYECEECGKAFIGSSALVIHQRVHTGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPYEC 350 360 370 380 390 400 410 420 430 440 450 pF1KB7 SDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKMAQPVG .::::.:: ::.:.:.::::.:. :. : :.:.. .::. :: .: NP_077 DDCGKTFSQSCSLLEHHRIHTGEKPYQCSMCGKAFRRSSHLLRHQRIHTGDKNVQEPEQG 410 420 430 440 450 460 NP_077 EAWKSRMESQLENVETPMSYKCNECERSFTQNTGLIEHQKIHTGEKPYQCNACGKGFTRI 470 480 490 500 510 520 >>XP_006715278 (OMIM: 612791) PREDICTED: zinc finger pro (538 aa) initn: 2033 init1: 584 opt: 960 Z-score: 635.6 bits: 127.1 E(85289): 1.2e-28 Smith-Waterman score: 1011; 38.7% identity (65.3% similar) in 447 aa overlap (18-451:22-448) 10 20 30 40 50 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDV ::..:::. :. . ::. :.::: : : .. XP_006 MARELSESTALDAQSTEDQMELLVIKVEE---EEAGFPSSPDLGSEGSRERFRGFRYPEA 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 HGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEA ::.::.:.: ::: .::.::...:::::::::::::::.:::..:.::::::: ::::. XP_006 AGPREALSRLRELCRQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEV 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 VALVEDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGAR--------RRPSV-P :.:.: :..: . : .... . . : : . ... .. :: XP_006 VVLLEYLERQLDEPAPQVSGVDQGQELLCCKMALLTPAPGSQSSQFQLMKALLKHESVGS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 QEQHSHSAQPPALLKEG--RPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRD : ... : :.: . : : ... . .. .: . . :. . .. :: : .: . XP_006 QPLQDRVLQVPVLAHGGCCREDKVVASRLTPESQGLLKVEDVALTLT-PEWTQQDSSQGN 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 LFWDIKRENSRNTTLGFGLKGQSEKSLLQEMVPV--VPGQTGSDVTVSWSPEEAEAWESE : : :.:: ... ...: . :... ... :. .: . . .. . :. XP_006 LCRDEKQEN-HGSLVSLGDEKQTKS---RDLPPAEELPEKEHGKISCHLREDIAQI---- 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 NRPRAALGPVVGARRGRPPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTHTGEK : : . : ..:: .:.: .. .. . : : .::: : .: :..:.: ::::: XP_006 --PTCAEA---GEQEGR--LQRKQ-KNATGGRRHICHECGKSFAQSSGLSKHRRIHTGEK 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB7 PHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFGC :..: :: :.: .:: :: :: :::::::. : ::::.::.:. : ::: ::::::. : XP_006 PYECEECGKAFIGSSALVIHQRVHTGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPYEC 350 360 370 380 390 400 410 420 430 440 450 pF1KB7 SDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKMAQPVG .::::.:: ::.:.:.::::.:. :. : :.:.. .::. :: .: XP_006 DDCGKTFSQSCSLLEHHRIHTGEKPYQCSMCGKAFRRSSHLLRHQRIHTGDKNVQEPEQG 410 420 430 440 450 460 XP_006 EAWKSRMESQLENVETPMSYKCNECERSFTQNTGLIEHQKIHTGEKPYQCNACGKGFTRI 470 480 490 500 510 520 >>NP_001229823 (OMIM: 612791) zinc finger protein with K (538 aa) initn: 2033 init1: 584 opt: 960 Z-score: 635.6 bits: 127.1 E(85289): 1.2e-28 Smith-Waterman score: 1011; 38.7% identity (65.3% similar) in 447 aa overlap (18-451:22-448) 10 20 30 40 50 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDV ::..:::. :. . ::. :.::: : : .. NP_001 MARELSESTALDAQSTEDQMELLVIKVEE---EEAGFPSSPDLGSEGSRERFRGFRYPEA 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 HGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEA ::.::.:.: ::: .::.::...:::::::::::::::.:::..:.::::::: ::::. NP_001 AGPREALSRLRELCRQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEV 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 VALVEDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGAR--------RRPSV-P :.:.: :..: . : .... . . : : . ... .. :: NP_001 VVLLEYLERQLDEPAPQVSGVDQGQELLCCKMALLTPAPGSQSSQFQLMKALLKHESVGS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 QEQHSHSAQPPALLKEG--RPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRD : ... : :.: . : : ... . .. .: . . :. . .. :: : .: . NP_001 QPLQDRVLQVPVLAHGGCCREDKVVASRLTPESQGLLKVEDVALTLT-PEWTQQDSSQGN 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 LFWDIKRENSRNTTLGFGLKGQSEKSLLQEMVPV--VPGQTGSDVTVSWSPEEAEAWESE : : :.:: ... ...: . :... ... :. .: . . .. . :. NP_001 LCRDEKQEN-HGSLVSLGDEKQTKS---RDLPPAEELPEKEHGKISCHLREDIAQI---- 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 NRPRAALGPVVGARRGRPPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTHTGEK : : . : ..:: .:.: .. .. . : : .::: : .: :..:.: ::::: NP_001 --PTCAEA---GEQEGR--LQRKQ-KNATGGRRHICHECGKSFAQSSGLSKHRRIHTGEK 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB7 PHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFGC :..: :: :.: .:: :: :: :::::::. : ::::.::.:. : ::: ::::::. : NP_001 PYECEECGKAFIGSSALVIHQRVHTGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPYEC 350 360 370 380 390 400 410 420 430 440 450 pF1KB7 SDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKMAQPVG .::::.:: ::.:.:.::::.:. :. : :.:.. .::. :: .: NP_001 DDCGKTFSQSCSLLEHHRIHTGEKPYQCSMCGKAFRRSSHLLRHQRIHTGDKNVQEPEQG 410 420 430 440 450 460 NP_001 EAWKSRMESQLENVETPMSYKCNECERSFTQNTGLIEHQKIHTGEKPYQCNACGKGFTRI 470 480 490 500 510 520 >>NP_001308045 (OMIM: 165260) zinc finger and SCAN domai (491 aa) initn: 3245 init1: 592 opt: 955 Z-score: 632.8 bits: 126.4 E(85289): 1.7e-28 Smith-Waterman score: 985; 38.6% identity (61.8% similar) in 477 aa overlap (1-451:1-458) 10 20 30 40 50 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRD----SEACRQRFRQFCYGDV :: : .. . .: : ...: ::::. . : :...: ::: : :::.: : .. NP_001 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 HGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEA :::::...: :::.::.:: ..:::::::::::::: .:: :::.:: : : ::::: NP_001 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 VALVEDL-QKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSA ..::::: : ..: : :. ::: ..:. .: . .: . . . NP_001 AVLVEDLTQVLDKRGW--D-PG--AEP------TEASCKQSDLGESEPSNVTETLMGGVS 130 140 150 160 180 190 200 210 220 230 pF1KB7 QPPALLKEGRPGETTDTCFVSGVHGPVALGDIP--FYFSREEWGTLDPAQRDLFWDIK-R ::..: .: ... ::. : . .. ..:.. : : .:. : . : NP_001 LGPAFVKACEPEGSSER---SGLSGEIWTKSVTQQIHFKK----TSGP-YKDVPTDQRGR 170 180 190 200 210 220 240 250 260 270 pF1KB7 EN--SRNTTLGFGLKGQSEKSLLQEMVPVV------PGQTGSDVTVSWSPE------EAE :. :::.. .. ..:: .. .: : : : : : : NP_001 ESGASRNSSSAWPNLTSQEKPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSAS 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB7 AWESENRPRAALGPVVGARRGRPPTRRRQFRDL----AAEKPHSCGQCGKRFRWGSDLAR : :.... .. : . .. :. .: .. . .. ::: : .::: : . :.. NP_001 ALEAHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQ 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB7 HQRTHTGEKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRI ::: ::::::.:: :: :.: :. :..:: :::::.:. :. :::.::.:..:..:::: NP_001 HQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRI 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB7 HTGEKPFGCSDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKM ::::::. :. ::..:: : :. : :.:.::.:. : : :.: : . :: :: .: NP_001 HTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGE 410 420 430 440 450 460 pF1KB7 AQPVG NP_001 KPYKCSDCGKAFSRSSALMVHLRIHITVLQ 470 480 490 >>NP_862829 (OMIM: 165260) zinc finger and SCAN domain-c (491 aa) initn: 3245 init1: 592 opt: 955 Z-score: 632.8 bits: 126.4 E(85289): 1.7e-28 Smith-Waterman score: 985; 38.6% identity (61.8% similar) in 477 aa overlap (1-451:1-458) 10 20 30 40 50 pF1KB7 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRD----SEACRQRFRQFCYGDV :: : .. . .: : ...: ::::. . : :...: ::: : :::.: : .. NP_862 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 HGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEA :::::...: :::.::.:: ..:::::::::::::: .:: :::.:: : : ::::: NP_862 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 VALVEDL-QKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSA ..::::: : ..: : :. ::: ..:. .: . .: . . . NP_862 AVLVEDLTQVLDKRGW--D-PG--AEP------TEASCKQSDLGESEPSNVTETLMGGVS 130 140 150 160 180 190 200 210 220 230 pF1KB7 QPPALLKEGRPGETTDTCFVSGVHGPVALGDIP--FYFSREEWGTLDPAQRDLFWDIK-R ::..: .: ... ::. : . .. ..:.. : : .:. : . : NP_862 LGPAFVKACEPEGSSER---SGLSGEIWTKSVTQQIHFKK----TSGP-YKDVPTDQRGR 170 180 190 200 210 220 240 250 260 270 pF1KB7 EN--SRNTTLGFGLKGQSEKSLLQEMVPVV------PGQTGSDVTVSWSPE------EAE :. :::.. .. ..:: .. .: : : : : : : NP_862 ESGASRNSSSAWPNLTSQEKPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSAS 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB7 AWESENRPRAALGPVVGARRGRPPTRRRQFRDL----AAEKPHSCGQCGKRFRWGSDLAR : :.... .. : . .. :. .: .. . .. ::: : .::: : . :.. NP_862 ALEAHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQ 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB7 HQRTHTGEKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRI ::: ::::::.:: :: :.: :. :..:: :::::.:. :. :::.::.:..:..:::: NP_862 HQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRI 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB7 HTGEKPFGCSDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKM ::::::. :. ::..:: : :. : :.:.::.:. : : :.: : . :: :: .: NP_862 HTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGE 410 420 430 440 450 460 pF1KB7 AQPVG NP_862 KPYKCSDCGKAFSRSSALMVHLRIHITVLQ 470 480 490 459 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:19:50 2016 done: Fri Nov 4 22:19:51 2016 Total Scan time: 11.070 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]