Result of FASTA (omim) for pF1KB7801
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7801, 519 aa
  1>>>pF1KB7801 519 - 519 aa - 519 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.9187+/-0.000378; mu= -1.9097+/- 0.024
 mean_var=255.9396+/-49.736, 0's: 0 Z-trim(122.1): 27  B-trim: 0 in 0/58
 Lambda= 0.080169
 statistics sampled from 39571 (39601) to 39571 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.464), width:  16
 Scan time: 12.810

The best scores are:                                      opt bits E(85289)
NP_919047 (OMIM: 608834) cyclic AMP-responsive ele ( 520) 3383 404.3 4.5e-112
NP_001305175 (OMIM: 608834) cyclic AMP-responsive  ( 457) 2970 356.5 9.8e-98
XP_016868030 (OMIM: 608834) PREDICTED: cyclic AMP- ( 457) 2970 356.5 9.8e-98
XP_016868029 (OMIM: 608834) PREDICTED: cyclic AMP- ( 457) 2970 356.5 9.8e-98
XP_005250598 (OMIM: 608834) PREDICTED: cyclic AMP- ( 457) 2970 356.5 9.8e-98
NP_001240704 (OMIM: 608834) cyclic AMP-responsive  ( 248) 1272 159.9 7.9e-39
NP_443086 (OMIM: 616215) cyclic AMP-responsive ele ( 519) 1080 137.9 6.9e-32
XP_006718443 (OMIM: 616215) PREDICTED: cyclic AMP- ( 363)  830 108.9 2.6e-23
NP_001258925 (OMIM: 611998) cyclic AMP-responsive  ( 459)  456 65.7 3.3e-10
NP_001258924 (OMIM: 611998) cyclic AMP-responsive  ( 460)  456 65.7 3.3e-10
NP_115996 (OMIM: 611998) cyclic AMP-responsive ele ( 461)  456 65.7 3.3e-10
XP_016855861 (OMIM: 607138) PREDICTED: cyclic AMP- ( 375)  429 62.5 2.5e-09
XP_006711235 (OMIM: 607138) PREDICTED: cyclic AMP- ( 375)  429 62.5 2.5e-09
NP_001242910 (OMIM: 607138) cyclic AMP-responsive  ( 375)  429 62.5 2.5e-09
NP_001242909 (OMIM: 607138) cyclic AMP-responsive  ( 375)  429 62.5 2.5e-09
NP_001242908 (OMIM: 607138) cyclic AMP-responsive  ( 395)  429 62.6 2.6e-09
NP_001242907 (OMIM: 607138) cyclic AMP-responsive  ( 395)  429 62.6 2.6e-09
NP_570968 (OMIM: 607138) cyclic AMP-responsive ele ( 395)  429 62.6 2.6e-09
NP_006359 (OMIM: 606443) cyclic AMP-responsive ele ( 371)  378 56.6 1.5e-07


>>NP_919047 (OMIM: 608834) cyclic AMP-responsive element  (520 aa)
 initn: 2740 init1: 2740 opt: 3383  Z-score: 2133.0  bits: 404.3 E(85289): 4.5e-112
Smith-Waterman score: 3383; 99.6% identity (99.8% similar) in 520 aa overlap (1-519:1-520)

               10        20        30        40        50        60
pF1KB7 MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEK
               10        20        30        40        50        60

               70        80        90        100       110         
pF1KB7 SVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQSPFTHIT-SDSFNDDEVESEKWYLSTDF
       ::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_919 SVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQSPFTHITTSDSFNDDEVESEKWYLSTDF
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB7 PSTSIKTEPITDEPPPGLVPSVTLTITAISTPLEKEEPPLEMNTGVDSSCQTIIPKIKLE
       :::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 PSTSIKTEPVTDEPPPGLVPSVTLTITAISTPLEKEEPPLEMNTGVDSSCQTIIPKIKLE
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB7 PHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 PHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAP
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB7 RAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRTLIAEGYPIPTKLPLSKSEEKALKKIRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 RAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRTLIAEGYPIPTKLPLSKSEEKALKKIRR
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB7 KIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 KIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTL
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB7 VMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHSLQEPYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 VMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHSLQEPYT
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB7 ASVVRSRNLLIYEEHSPPEESSSPGSAGELGGWDRGSSLLRVSGLESRPDVDLPHFIISN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 ASVVRSRNLLIYEEHSPPEESSSPGSAGELGGWDRGSSLLRVSGLESRPDVDLPHFIISN
              430       440       450       460       470       480

     480       490       500       510         
pF1KB7 ETSLEKSVLLELQQHLVSAKLEGNETLKVVELDRRVNTTF
       ::::::::::::::::::::::::::::::::::::::::
NP_919 ETSLEKSVLLELQQHLVSAKLEGNETLKVVELDRRVNTTF
              490       500       510       520

>>NP_001305175 (OMIM: 608834) cyclic AMP-responsive elem  (457 aa)
 initn: 2740 init1: 2740 opt: 2970  Z-score: 1875.7  bits: 356.5 E(85289): 9.8e-98
Smith-Waterman score: 2970; 99.6% identity (99.8% similar) in 457 aa overlap (64-519:1-457)

            40        50        60        70        80        90   
pF1KB7 THFSELLDEFSQNVLGQLLNDPFLSEKSVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQS
                                     ::::::::::::::::::::::::::::::
NP_001                               MEVEPSPTSPAPLIQAEHSYSLCEEPRAQS
                                             10        20        30

            100       110       120       130       140       150  
pF1KB7 PFTHIT-SDSFNDDEVESEKWYLSTDFPSTSIKTEPITDEPPPGLVPSVTLTITAISTPL
       :::::: :::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_001 PFTHITTSDSFNDDEVESEKWYLSTDFPSTSIKTEPVTDEPPPGLVPSVTLTITAISTPL
               40        50        60        70        80        90

            160       170       180       190       200       210  
pF1KB7 EKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSD
              100       110       120       130       140       150

            220       230       240       250       260       270  
pF1KB7 SEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRT
              160       170       180       190       200       210

            280       290       300       310       320       330  
pF1KB7 LIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTEN
              220       230       240       250       260       270

            340       350       360       370       380       390  
pF1KB7 LELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGS
              280       290       300       310       320       330

            400       410       420       430       440       450  
pF1KB7 FFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGW
              340       350       360       370       380       390

            460       470       480       490       500       510  
pF1KB7 DRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELD
              400       410       420       430       440       450

              
pF1KB7 RRVNTTF
       :::::::
NP_001 RRVNTTF
              

>>XP_016868030 (OMIM: 608834) PREDICTED: cyclic AMP-resp  (457 aa)
 initn: 2740 init1: 2740 opt: 2970  Z-score: 1875.7  bits: 356.5 E(85289): 9.8e-98
Smith-Waterman score: 2970; 99.6% identity (99.8% similar) in 457 aa overlap (64-519:1-457)

            40        50        60        70        80        90   
pF1KB7 THFSELLDEFSQNVLGQLLNDPFLSEKSVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQS
                                     ::::::::::::::::::::::::::::::
XP_016                               MEVEPSPTSPAPLIQAEHSYSLCEEPRAQS
                                             10        20        30

            100       110       120       130       140       150  
pF1KB7 PFTHIT-SDSFNDDEVESEKWYLSTDFPSTSIKTEPITDEPPPGLVPSVTLTITAISTPL
       :::::: :::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 PFTHITTSDSFNDDEVESEKWYLSTDFPSTSIKTEPVTDEPPPGLVPSVTLTITAISTPL
               40        50        60        70        80        90

            160       170       180       190       200       210  
pF1KB7 EKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSD
              100       110       120       130       140       150

            220       230       240       250       260       270  
pF1KB7 SEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRT
              160       170       180       190       200       210

            280       290       300       310       320       330  
pF1KB7 LIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTEN
              220       230       240       250       260       270

            340       350       360       370       380       390  
pF1KB7 LELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGS
              280       290       300       310       320       330

            400       410       420       430       440       450  
pF1KB7 FFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGW
              340       350       360       370       380       390

            460       470       480       490       500       510  
pF1KB7 DRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELD
              400       410       420       430       440       450

              
pF1KB7 RRVNTTF
       :::::::
XP_016 RRVNTTF
              

>>XP_016868029 (OMIM: 608834) PREDICTED: cyclic AMP-resp  (457 aa)
 initn: 2740 init1: 2740 opt: 2970  Z-score: 1875.7  bits: 356.5 E(85289): 9.8e-98
Smith-Waterman score: 2970; 99.6% identity (99.8% similar) in 457 aa overlap (64-519:1-457)

            40        50        60        70        80        90   
pF1KB7 THFSELLDEFSQNVLGQLLNDPFLSEKSVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQS
                                     ::::::::::::::::::::::::::::::
XP_016                               MEVEPSPTSPAPLIQAEHSYSLCEEPRAQS
                                             10        20        30

            100       110       120       130       140       150  
pF1KB7 PFTHIT-SDSFNDDEVESEKWYLSTDFPSTSIKTEPITDEPPPGLVPSVTLTITAISTPL
       :::::: :::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 PFTHITTSDSFNDDEVESEKWYLSTDFPSTSIKTEPVTDEPPPGLVPSVTLTITAISTPL
               40        50        60        70        80        90

            160       170       180       190       200       210  
pF1KB7 EKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSD
              100       110       120       130       140       150

            220       230       240       250       260       270  
pF1KB7 SEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRT
              160       170       180       190       200       210

            280       290       300       310       320       330  
pF1KB7 LIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTEN
              220       230       240       250       260       270

            340       350       360       370       380       390  
pF1KB7 LELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGS
              280       290       300       310       320       330

            400       410       420       430       440       450  
pF1KB7 FFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGW
              340       350       360       370       380       390

            460       470       480       490       500       510  
pF1KB7 DRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELD
              400       410       420       430       440       450

              
pF1KB7 RRVNTTF
       :::::::
XP_016 RRVNTTF
              

>>XP_005250598 (OMIM: 608834) PREDICTED: cyclic AMP-resp  (457 aa)
 initn: 2740 init1: 2740 opt: 2970  Z-score: 1875.7  bits: 356.5 E(85289): 9.8e-98
Smith-Waterman score: 2970; 99.6% identity (99.8% similar) in 457 aa overlap (64-519:1-457)

            40        50        60        70        80        90   
pF1KB7 THFSELLDEFSQNVLGQLLNDPFLSEKSVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQS
                                     ::::::::::::::::::::::::::::::
XP_005                               MEVEPSPTSPAPLIQAEHSYSLCEEPRAQS
                                             10        20        30

            100       110       120       130       140       150  
pF1KB7 PFTHIT-SDSFNDDEVESEKWYLSTDFPSTSIKTEPITDEPPPGLVPSVTLTITAISTPL
       :::::: :::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_005 PFTHITTSDSFNDDEVESEKWYLSTDFPSTSIKTEPVTDEPPPGLVPSVTLTITAISTPL
               40        50        60        70        80        90

            160       170       180       190       200       210  
pF1KB7 EKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSD
              100       110       120       130       140       150

            220       230       240       250       260       270  
pF1KB7 SEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRT
              160       170       180       190       200       210

            280       290       300       310       320       330  
pF1KB7 LIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTEN
              220       230       240       250       260       270

            340       350       360       370       380       390  
pF1KB7 LELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGS
              280       290       300       310       320       330

            400       410       420       430       440       450  
pF1KB7 FFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGW
              340       350       360       370       380       390

            460       470       480       490       500       510  
pF1KB7 DRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELD
              400       410       420       430       440       450

              
pF1KB7 RRVNTTF
       :::::::
XP_005 RRVNTTF
              

>>NP_001240704 (OMIM: 608834) cyclic AMP-responsive elem  (248 aa)
 initn: 667 init1: 667 opt: 1272  Z-score: 818.1  bits: 159.9 E(85289): 7.9e-39
Smith-Waterman score: 1272; 99.0% identity (99.5% similar) in 194 aa overlap (1-193:1-194)

               10        20        30        40        50        60
pF1KB7 MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEK
               10        20        30        40        50        60

               70        80        90        100       110         
pF1KB7 SVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQSPFTHIT-SDSFNDDEVESEKWYLSTDF
       ::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_001 SVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQSPFTHITTSDSFNDDEVESEKWYLSTDF
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB7 PSTSIKTEPITDEPPPGLVPSVTLTITAISTPLEKEEPPLEMNTGVDSSCQTIIPKIKLE
       :::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSTSIKTEPVTDEPPPGLVPSVTLTITAISTPLEKEEPPLEMNTGVDSSCQTIIPKIKLE
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB7 PHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAP
       ::::::::::::::                                              
NP_001 PHEVDQFLNFSPKEGLSALPVSLWVMDMVSGSTEREYGERAGMSLYHRCCSWLYEIALFL
              190       200       210       220       230       240

>>NP_443086 (OMIM: 616215) cyclic AMP-responsive element  (519 aa)
 initn: 803 init1: 710 opt: 1080  Z-score: 693.5  bits: 137.9 E(85289): 6.9e-32
Smith-Waterman score: 1179; 51.6% identity (74.4% similar) in 403 aa overlap (35-433:42-430)

           10        20        30        40        50        60    
pF1KB7 ESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEKSVSM
                                     ::.: ...::.........:: :.:::  .
NP_443 RLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFTENMEDFSNDLFSSFFDDPVLDEKSPLL
              20        30        40        50        60        70 

           70        80        90       100       110       120    
pF1KB7 EVEPSPTSPAPLIQAEHSYSLCEEPRAQSPFTHITSDSFNDDEVESEKWYLSTDFPSTSI
       ..: .  ::.: :::::::::  .   :::.. :  .. ..: .:   : :.  . :  .
NP_443 DMELD--SPTPGIQAEHSYSLSGDSAPQSPLVPIKMEDTTQD-AEHGAWALGHKLCSIMV
                80        90       100       110        120        

          130        140        150       160       170        180 
pF1KB7 KTEPITDEP-PPGLVPSVTLTITAI-STPLEKEEPPLEMNTGVDSSCQ-TIIPKIKLEPH
       : :   . :  :  .::.  . .:. .:::    :  ..    ..  . : .: :: :: 
NP_443 KQEQSPELPVDPLAAPSAMAAAAAMATTPLLGLSPLSRLPIPHQAPGEMTQLPVIKAEPL
      130       140       150       160       170       180        

             190       200       210       220       230       240 
pF1KB7 EVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAPRA
       ::.:::. .:.    : ...::::::::::::.:: ::       ::: . :: :   :.
NP_443 EVNQFLKVTPE----DLVQMPPTPPSSHGSDSDGSQSPR------SLPPS-SPVRPMARS
      190           200       210       220              230       

             250        260       270       280       290       300
pF1KB7 PSALSSSPLLTAPHKLQG-SGPLVLTEEEKRTLIAEGYPIPTKLPLSKSEEKALKKIRRK
        .:.:.:::::::::::: ::::.::::::::::::::::::::::.:.::::::..:::
NP_443 STAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRK
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB7 IKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLV
       :::::::::::::::::.. ::::::. ..:: :: ::::.:::.:::::::::::::::
NP_443 IKNKISAQESRRKKKEYVECLEKKVETFTSENNELWKKVETLENANRTLLQQLQKLQTLV
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KB7 MGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHSLQEPYTA
        .:.::  :.:.:::::::::..:::....::.      . :... .  .  . .  :::
NP_443 TNKISRPYKMAATQTGTCLMVAALCFVLVLGSLVPCLPEFSSGSQTVKEDPLAADGVYTA
       360       370       380       390       400       410       

              430       440       450       460       470       480
pF1KB7 SVVRSRNLLIYEEHSPPEESSSPGSAGELGGWDRGSSLLRVSGLESRPDVDLPHFIISNE
       : . ::.::.:..                                               
NP_443 SQMPSRSLLFYDDGAGLWEDGRSTLLPMEPPDGWEINPGGPAEQRPRDHLQHDHLDSTHE
       420       430       440       450       460       470       

>>XP_006718443 (OMIM: 616215) PREDICTED: cyclic AMP-resp  (363 aa)
 initn: 790 init1: 449 opt: 830  Z-score: 539.4  bits: 108.9 E(85289): 2.6e-23
Smith-Waterman score: 929; 50.6% identity (72.9% similar) in 332 aa overlap (35-362:42-358)

           10        20        30        40        50        60    
pF1KB7 ESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEKSVSM
                                     ::.: ...::.........:: :.:::  .
XP_006 RLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFTENMEDFSNDLFSSFFDDPVLDEKSPLL
              20        30        40        50        60        70 

           70        80        90       100       110       120    
pF1KB7 EVEPSPTSPAPLIQAEHSYSLCEEPRAQSPFTHITSDSFNDDEVESEKWYLSTDFPSTSI
       ..: .  ::.: :::::::::  .   :::.. :  .. ..: .:   : :.  . :  .
XP_006 DMELD--SPTPGIQAEHSYSLSGDSAPQSPLVPIKMEDTTQD-AEHGAWALGHKLCSIMV
                80        90       100       110        120        

          130        140        150       160       170        180 
pF1KB7 KTEPITDEP-PPGLVPSVTLTITAI-STPLEKEEPPLEMNTGVDSSCQ-TIIPKIKLEPH
       : :   . :  :  .::.  . .:. .:::    :  ..    ..  . : .: :: :: 
XP_006 KQEQSPELPVDPLAAPSAMAAAAAMATTPLLGLSPLSRLPIPHQAPGEMTQLPVIKAEPL
      130       140       150       160       170       180        

             190       200       210       220       230       240 
pF1KB7 EVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAPRA
       ::.:::. .:.    : ...::::::::::::.:: ::       ::: . :: :   :.
XP_006 EVNQFLKVTPE----DLVQMPPTPPSSHGSDSDGSQSPR------SLPPS-SPVRPMARS
      190           200       210       220              230       

             250        260       270       280       290       300
pF1KB7 PSALSSSPLLTAPHKLQG-SGPLVLTEEEKRTLIAEGYPIPTKLPLSKSEEKALKKIRRK
        .:.:.:::::::::::: ::::.::::::::::::::::::::::.:.::::::..:::
XP_006 STAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRK
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB7 IKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLV
       :::::::::::::::::.. ::::::. ..:: :: ::::.:::.: .. . .: :   .
XP_006 IKNKISAQESRRKKKEYVECLEKKVETFTSENNELWKKVETLENAN-SFSSGIQPLLCSL
       300       310       320       330       340        350      

              370       380       390       400       410       420
pF1KB7 MGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHSLQEPYTA
       .:                                                          
XP_006 IGLENPT                                                     
        360                                                        

>>NP_001258925 (OMIM: 611998) cyclic AMP-responsive elem  (459 aa)
 initn: 422 init1: 389 opt: 456  Z-score: 304.2  bits: 65.7 E(85289): 3.3e-10
Smith-Waterman score: 457; 32.3% identity (58.1% similar) in 375 aa overlap (158-490:78-437)

       130       140       150       160       170       180       
pF1KB7 PITDEPPPGLVPSVTLTITAISTPLEKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFL
                                     ::    : ::. .  .:.   .:...    
NP_001 HVKDQQVLPNPDSDDFLSSILGSGDSLPSSPLWSPEGSDSGISEDLPS---DPQDTPP--
        50        60        70        80        90          100    

       190        200         210       220             230        
pF1KB7 NFSPKEAPVD-HLHLPPTPP--SSHGSDSEGSLSPNPRLH-P-----FSLPQTHSPSRAA
         .:  .:.  :   :   :  : : ..: .. .:.: .. :     ..: .    .:  
NP_001 RSGPATSPAGCHPAQPGKGPCLSYHPGNSCSTTTPGPVIQVPEASVTIDLEMWSPGGRIC
            110       120       130       140       150       160  

      240                 250                  260          270    
pF1KB7 PRAPS-ALSSSP---------LLTAP----HKL-------QGSG---PLVLTEEEKRTLI
        . :.  .. ::         ::..     :.:        :.:    :::::.::. : 
NP_001 AEKPADPVDLSPRCNLTVKDLLLSGSSGDLHHLGASYLLRPGAGHCQELVLTEDEKKLLA
            170       180       190       200       210       220  

          280       290       300       310       320       330    
pF1KB7 AEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLE
        ::  .::.:::.: ::..::::::::.:: ::::::.:::::.:.:: .. .:...: :
NP_001 KEGITLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQE
            230       240       250       260       270       280  

          340       350       360       370       380       390    
pF1KB7 LRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFF
       :..::  ::. : .::.::.:::..:. ..:..     .:::::. :..: ::. .   .
NP_001 LQRKVLHLEKQNLSLLEQLKKLQAIVVQSTSKS-----AQTGTCVAVLLLSFALIILPSI
            290       300       310            320       330       

          400       410          420       430        440          
pF1KB7 QGYGPYPSATKMALPSQHSLQEPY---TASVVRSRNLLIYEEHSP-PEESS----SPGSA
       . .::  . .   .   . ...     .:: : .  .   :  .: :: ..    :::: 
NP_001 SPFGPNKTESPGDFAPVRVFSRTLHNDAASRVAADAVPGSEAPGPRPEADTTREESPGSP
       340       350       360       370       380       390       

        450       460       470       480        490       500     
pF1KB7 GELGGWDRGSSLLRVSGLESRPDVDLPHFIISNET-SLEKSVLLELQQHLVSAKLEGNET
       :   :..  ..:      .:  ..:   ... : : .: . .::.               
NP_001 GADWGFQDTANL-----TNSTEELDNATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGL
       400            410       420       430       440       450  

         510         
pF1KB7 LKVVELDRRVNTTF
                     
NP_001 EAAGDEL       
                     

>>NP_001258924 (OMIM: 611998) cyclic AMP-responsive elem  (460 aa)
 initn: 422 init1: 389 opt: 456  Z-score: 304.2  bits: 65.7 E(85289): 3.3e-10
Smith-Waterman score: 456; 38.8% identity (66.7% similar) in 237 aa overlap (263-490:212-438)

            240       250       260       270       280       290  
pF1KB7 SPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRTLIAEGYPIPTKLPLSKSEEK
                                     :::::.::. :  ::  .::.:::.: ::.
NP_001 LLLSGSSGDLQQHHLGASYLLRPGAGHCQELVLTEDEKKLLAKEGITLPTQLPLTKYEER
             190       200       210       220       230       240 

            300       310       320       330       340       350  
pF1KB7 ALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQ
       .::::::::.:: ::::::.:::::.:.:: .. .:...: ::..::  ::. : .::.:
NP_001 VLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNLSLLEQ
             250       260       270       280       290       300 

            360       370       380       390       400       410  
pF1KB7 LQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQH
       :.:::..:. ..:..     .:::::. :..: ::. .   .. .::  . .   .   .
NP_001 LKKLQAIVVQSTSKS-----AQTGTCVAVLLLSFALIILPSISPFGPNKTESPGDFAPVR
             310            320       330       340       350      

               420       430        440           450       460    
pF1KB7 SLQEPY---TASVVRSRNLLIYEEHSP-PEESS----SPGSAGELGGWDRGSSLLRVSGL
        ...     .:: : .  .   :  .: :: ..    :::: :   :..  ..:      
NP_001 VFSRTLHNDAASRVAADAVPGSEAPGPRPEADTTREESPGSPGADWGFQDTANLT-----
        360       370       380       390       400       410      

          470       480        490       500       510         
pF1KB7 ESRPDVDLPHFIISNET-SLEKSVLLELQQHLVSAKLEGNETLKVVELDRRVNTTF
       .:  ..:   ... : : .: . .::.                             
NP_001 NSTEELDNATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGLEAAGDEL       
             420       430       440       450       460       




519 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 22:22:18 2016 done: Fri Nov  4 22:22:20 2016
 Total Scan time: 12.810 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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