FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7803, 503 aa 1>>>pF1KB7803 503 - 503 aa - 503 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9856+/-0.0004; mu= 16.0883+/- 0.025 mean_var=96.1045+/-19.452, 0's: 0 Z-trim(113.4): 50 B-trim: 0 in 0/53 Lambda= 0.130829 statistics sampled from 22668 (22717) to 22668 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.266), width: 16 Scan time: 9.890 The best scores are: opt bits E(85289) NP_001035199 (OMIM: 600879) nuclear respiratory fa ( 503) 3199 614.4 2.4e-175 NP_005002 (OMIM: 600879) nuclear respiratory facto ( 503) 3199 614.4 2.4e-175 NP_001280092 (OMIM: 600879) nuclear respiratory fa ( 522) 2898 557.6 3.1e-158 NP_001280093 (OMIM: 600879) nuclear respiratory fa ( 342) 2171 420.3 4.5e-117 >>NP_001035199 (OMIM: 600879) nuclear respiratory factor (503 aa) initn: 3199 init1: 3199 opt: 3199 Z-score: 3269.1 bits: 614.4 E(85289): 2.4e-175 Smith-Waterman score: 3199; 100.0% identity (100.0% similar) in 503 aa overlap (1-503:1-503) 10 20 30 40 50 60 pF1KB7 MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 STAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 ANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 VPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 ATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 ATLQGGGQIVLSGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATLQGGGQIVLSGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPV 430 440 450 460 470 480 490 500 pF1KB7 TTRISDSAVTMDGQAVEVVTLEQ ::::::::::::::::::::::: NP_001 TTRISDSAVTMDGQAVEVVTLEQ 490 500 >>NP_005002 (OMIM: 600879) nuclear respiratory factor 1 (503 aa) initn: 3199 init1: 3199 opt: 3199 Z-score: 3269.1 bits: 614.4 E(85289): 2.4e-175 Smith-Waterman score: 3199; 100.0% identity (100.0% similar) in 503 aa overlap (1-503:1-503) 10 20 30 40 50 60 pF1KB7 MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 STAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 STAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 ANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 VPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 ATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 ATLQGGGQIVLSGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ATLQGGGQIVLSGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPV 430 440 450 460 470 480 490 500 pF1KB7 TTRISDSAVTMDGQAVEVVTLEQ ::::::::::::::::::::::: NP_005 TTRISDSAVTMDGQAVEVVTLEQ 490 500 >>NP_001280092 (OMIM: 600879) nuclear respiratory factor (522 aa) initn: 2898 init1: 2898 opt: 2898 Z-score: 2961.8 bits: 557.6 E(85289): 3.1e-158 Smith-Waterman score: 3151; 96.4% identity (96.4% similar) in 522 aa overlap (1-503:1-522) 10 20 30 40 50 60 pF1KB7 MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 STAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 ANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 VPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 ATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAE 370 380 390 400 410 420 430 440 450 460 pF1KB7 ATLQGGGQIVLSGETAAAVGALTGVQDANGL-------------------VQIPVSMYQT ::::::::::::::::::::::::::::::: :::::::::: NP_001 ATLQGGGQIVLSGETAAAVGALTGVQDANGLFMADRAGRKWILTDKATGLVQIPVSMYQT 430 440 450 460 470 480 470 480 490 500 pF1KB7 VVTSLAQGNGPVQVAMAPVTTRISDSAVTMDGQAVEVVTLEQ :::::::::::::::::::::::::::::::::::::::::: NP_001 VVTSLAQGNGPVQVAMAPVTTRISDSAVTMDGQAVEVVTLEQ 490 500 510 520 >>NP_001280093 (OMIM: 600879) nuclear respiratory factor (342 aa) initn: 2171 init1: 2171 opt: 2171 Z-score: 2222.8 bits: 420.3 E(85289): 4.5e-117 Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 342 aa overlap (162-503:1-342) 140 150 160 170 180 190 pF1KB7 VLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQEVNSELPPLTID :::::::::::::::::::::::::::::: NP_001 MILEDLESALAEHAPAPQEVNSELPPLTID 10 20 30 200 210 220 230 240 250 pF1KB7 GIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEE 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB7 QKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHLVPSQTVVQTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHLVPSQTVVQTFS 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB7 NPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNWATLQGGEMTIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNWATLQGGEMTIQ 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB7 TTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAEATLQGGGQIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAEATLQGGGQIVL 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB7 SGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPVTTRISDSAVTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPVTTRISDSAVTM 280 290 300 310 320 330 500 pF1KB7 DGQAVEVVTLEQ :::::::::::: NP_001 DGQAVEVVTLEQ 340 503 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:22:59 2016 done: Fri Nov 4 22:23:01 2016 Total Scan time: 9.890 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]