FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7819, 535 aa
1>>>pF1KB7819 535 - 535 aa - 535 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4241+/-0.000928; mu= 1.9577+/- 0.056
mean_var=268.9630+/-54.668, 0's: 0 Z-trim(115.0): 32 B-trim: 162 in 1/50
Lambda= 0.078204
statistics sampled from 15777 (15806) to 15777 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.473), width: 16
Scan time: 1.790
The best scores are: opt bits E(33420)
CCDS11514.1 TBX21 gene_id:30009|Hs109|chr17 ( 535) 3821 444.2 1.8e-124
CCDS63585.1 EOMES gene_id:8320|Hs109|chr3 ( 705) 1145 142.4 1.7e-33
CCDS33310.1 TBR1 gene_id:10716|Hs109|chr2 ( 682) 1127 140.4 6.7e-33
CCDS2646.1 EOMES gene_id:8320|Hs109|chr3 ( 686) 1083 135.4 2.1e-31
CCDS63584.1 EOMES gene_id:8320|Hs109|chr3 ( 410) 935 118.5 1.5e-26
CCDS13767.1 TBX1 gene_id:6899|Hs109|chr22 ( 495) 716 93.9 4.8e-19
CCDS11629.1 TBX4 gene_id:9496|Hs109|chr17 ( 545) 713 93.6 6.5e-19
CCDS82180.1 TBX4 gene_id:9496|Hs109|chr17 ( 546) 713 93.6 6.5e-19
CCDS13765.1 TBX1 gene_id:6899|Hs109|chr22 ( 372) 697 91.6 1.7e-18
CCDS13766.1 TBX1 gene_id:6899|Hs109|chr22 ( 398) 697 91.7 1.8e-18
CCDS9173.1 TBX5 gene_id:6910|Hs109|chr12 ( 518) 685 90.4 5.6e-18
CCDS9174.1 TBX5 gene_id:6910|Hs109|chr12 ( 468) 682 90.0 6.6e-18
CCDS11627.2 TBX2 gene_id:6909|Hs109|chr17 ( 712) 679 89.9 1.1e-17
CCDS10670.1 TBX6 gene_id:6911|Hs109|chr16 ( 436) 663 87.9 2.8e-17
CCDS9175.1 TBX3 gene_id:6926|Hs109|chr12 ( 723) 642 85.7 2.1e-16
CCDS31621.1 TBX10 gene_id:347853|Hs109|chr11 ( 385) 634 84.5 2.4e-16
CCDS34495.1 TBX18 gene_id:9096|Hs109|chr6 ( 607) 636 84.9 2.9e-16
CCDS55960.1 MGA gene_id:23269|Hs109|chr15 (2856) 624 84.2 2.3e-15
CCDS55959.1 MGA gene_id:23269|Hs109|chr15 (3065) 624 84.2 2.5e-15
CCDS81360.1 TBX15 gene_id:6913|Hs109|chr1 ( 602) 582 78.8 2e-14
CCDS14445.1 TBX22 gene_id:50945|Hs109|chrX ( 520) 578 78.3 2.4e-14
CCDS43568.1 TBX20 gene_id:57057|Hs109|chr7 ( 447) 573 77.7 3.2e-14
CCDS30816.1 TBX15 gene_id:6913|Hs109|chr1 ( 496) 568 77.2 5.1e-14
CCDS1272.1 TBX19 gene_id:9095|Hs109|chr1 ( 448) 537 73.7 5.4e-13
CCDS59045.1 TBXT gene_id:6862|Hs109|chr6 ( 377) 492 68.5 1.6e-11
CCDS5290.1 TBXT gene_id:6862|Hs109|chr6 ( 435) 491 68.5 1.9e-11
>>CCDS11514.1 TBX21 gene_id:30009|Hs109|chr17 (535 aa)
initn: 3821 init1: 3821 opt: 3821 Z-score: 2348.4 bits: 444.2 E(33420): 1.8e-124
Smith-Waterman score: 3821; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535)
10 20 30 40 50 60
pF1KB7 MGIVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MGIVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 NQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 RGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEI
430 440 450 460 470 480
490 500 510 520 530
pF1KB7 APIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 APIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
490 500 510 520 530
>>CCDS63585.1 EOMES gene_id:8320|Hs109|chr3 (705 aa)
initn: 1143 init1: 1006 opt: 1145 Z-score: 715.1 bits: 142.4 E(33420): 1.7e-33
Smith-Waterman score: 1225; 44.5% identity (63.1% similar) in 539 aa overlap (34-512:143-674)
10 20 30 40 50
pF1KB7 VEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDAD----------ERRGGGS
::. :: : .. . .:.
CCDS63 ELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAP
120 130 140 150 160 170
60 70 80 90 100
pF1KB7 LGS--PYPGGALVPA----PPSRFLGAYAYPPRPQAAGFPGAGE-SFPPPADAEGYQPGE
: : :.:: : ::. : .: : : : . :::: : ... : ::
CCDS63 HGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFG--PGAGAGSGAGGSSGGGGGPGT
180 190 200 210 220 230
110 120 130 140 150 160
pF1KB7 -GYAAPDPRAGLYPGPREDYALPA--GLEVSG---KLRVALNNHLLWSKFNQHQTEMIIT
:. : : ::: . . :: : : . .: : :. :: ::..::::::::
CCDS63 YQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT
240 250 260 270 280 290
170 180 190 200 210 220
pF1KB7 KQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLY
::::::::::::.. ::.::.:: .::.:::.: .:::.:.:::: ::::...: ::..:
CCDS63 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMY
300 310 320 330 340 350
230 240 250 260 270 280
pF1KB7 VHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEP
:::.:::::.::::::.:::::::::::::.:: :::::::::::::::::::::..
CCDS63 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV
360 370 380 390 400 410
290 300 310 320 330
pF1KB7 EAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSV--DTS
: . :.:. :::.::::::::::::..:::::::.::::::::.:..::::. :
CCDS63 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRL
420 430 440 450 460 470
340 350 360 370 380
pF1KB7 IPSPP-GPNC-QFLGGDHYS--PLLPNQY--PVP-SRFY------PDL-----PGQAKDV
::: .: :.. : .:. ..:. . .: .:.: :. : :...:
CCDS63 TPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEV
480 490 500 510 520 530
390 400 410 420
pF1KB7 V-PQAYWLGAPRDH---------SYEAEFRAVSMKPAFLPSAPGPT---MSYYRGQEVLA
. : :: .: .. :::.:. . .. : . : : : ..:: . ..
CCDS63 ANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYY-PDPTFP
540 550 560 570 580
430 440 450 460 470 480
pF1KB7 PGAGWPVAPQYPPKMGPA-SWFRPMRTLPMEPGPGG-SEGRGPEDQGPPLVWTEIAP-IR
::: .: ::. . : :: : . :. . :. : : : : :.
CCDS63 AMAGWGGRGSYQRKMAAGLPWTS--RTSPTVFSEDQLSKEKVKEEIGSS--WIETPPSIK
590 600 610 620 630 640
490 500 510 520 530
pF1KB7 P-ESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
.:.:::. . ::::.:: ::...:
CCDS63 SLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
650 660 670 680 690 700
>>CCDS33310.1 TBR1 gene_id:10716|Hs109|chr2 (682 aa)
initn: 1077 init1: 1025 opt: 1127 Z-score: 704.3 bits: 140.4 E(33420): 6.7e-33
Smith-Waterman score: 1142; 42.8% identity (64.6% similar) in 495 aa overlap (57-527:125-588)
30 40 50 60 70 80
pF1KB7 PGADPQHRYFYPEPGAQDADERRGGGSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGF
:::: :: :. .:. : : :
CCDS33 HSFDGSAADRYLLSQSSQPQSAATAPSAMFPYPGQHG-PAHPAFSIGS---PSR-YMAHH
100 110 120 130 140
90 100 110 120 130 140
pF1KB7 P----GAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG-PREDYALPAGLEVSGKLRVAL
: :: .:. .. .:: : :: :. . : : : ... : :: .: :
CCDS33 PVITNGAYNSLLSNSSPQGY-PTAGYPYPQQYGHSYQGAPFYQFSSTQPGLVPGKAQVYL
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB7 NNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQS
:. :: ::..::::::::::::::::::::...::.::.:: .::::.:.: .:::.:.
CCDS33 CNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWRFQG
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB7 GKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQ
:::: ::::. .. :::.:.:::::::::::::::.:::::::::::::::: ::.:::
CCDS33 GKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQMVVLQ
270 280 290 300 310 320
270 280 290 300 310 320
pF1KB7 SLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFA
::::::::::.::::. : . . . .. ::: ::::::::::::..:::::::.::::
CCDS33 SLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFA
330 340 350 360 370 380
330 340 350 360 370
pF1KB7 KGFRENFESMYTSVDTS--IPSP-PGPNCQFLGGDHYS---PLLPNQYP---VPSRFYPD
::::.:....::. : . ::: .: :.. : .:. .: .:. . .::.:
CCDS33 KGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMAGSFLQDQFVSNYAKARFHPG
390 400 410 420 430 440
380 390 400 410 420
pF1KB7 L---PGQAKD-VVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYYR--GQEVL
:: . : ::.. : .:. .:: :.::.: . ....
CCDS33 AGAGPGPGTDRSVPHTNGLLSPQ----QAE----------DPGAPSPQRWFVTPANNRLD
450 460 470 480 490
430 440 450 460 470 480
pF1KB7 APGAGWPVAPQYPPKMGPASWFRP--MRTLPMEPGPGGSEGRGPEDQGPPLVWTEIAPIR
.... .: .. . . . ...::.. .: :: . : : .: .
CCDS33 FAASAYDTATDFAGNAATLLSYAAAGVKALPLQA--AGCTGRPLGYYADPSGWGARSPPQ
500 510 520 530 540 550
490 500 510 520 530
pF1KB7 PESSDSGLGEGDSKRRRVSP-YPSSGDSSSPAGAPSPF-DKEAEGQFYNYFPN
.. :: : : .:.:. ... .. .:. .::::
CCDS33 YCGTKSG---------SVLPCWPNSAAAAARMAGANPYLGEEAEGLAAERSPLPPGAAED
560 570 580 590 600
CCDS33 AKPKDLSDSSWIETPSSIKSIDSSDSGIYEQAKRRRISPADTPVSESSSPLKSEVLAQRD
610 620 630 640 650 660
>>CCDS2646.1 EOMES gene_id:8320|Hs109|chr3 (686 aa)
initn: 1137 init1: 972 opt: 1083 Z-score: 677.5 bits: 135.4 E(33420): 2.1e-31
Smith-Waterman score: 1190; 44.3% identity (62.2% similar) in 526 aa overlap (34-512:143-655)
10 20 30 40 50
pF1KB7 VEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDAD----------ERRGGGS
::. :: : .. . .:.
CCDS26 ELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAP
120 130 140 150 160 170
60 70 80 90 100
pF1KB7 LGS--PYPGGALVPA----PPSRFLGAYAYPPRPQAAGFPGAGE-SFPPPADAEGYQPGE
: : :.:: : ::. : .: : : : . :::: : ... : ::
CCDS26 HGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFG--PGAGAGSGAGGSSGGGGGPGT
180 190 200 210 220 230
110 120 130 140 150 160
pF1KB7 -GYAAPDPRAGLYPGPREDYALPA--GLEVSG---KLRVALNNHLLWSKFNQHQTEMIIT
:. : : ::: . . :: : : . .: : :. :: ::..::::::::
CCDS26 YQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT
240 250 260 270 280 290
170 180 190 200 210 220
pF1KB7 KQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLY
::::::::::::.. ::.::.:: .::.:::.: .:::.:.:::: ::::...: ::..:
CCDS26 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMY
300 310 320 330 340 350
230 240 250 260 270 280
pF1KB7 VHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEP
:::.:::::.::::::.:::::::::::::.:: :::::::::::::::::::::..
CCDS26 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV
360 370 380 390 400 410
290 300 310 320 330 340
pF1KB7 EAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIP
: . :.:. :::.::::::::::::..:::::::.::::::::.:..: . :
CCDS26 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSSHQIV-----
420 430 440 450 460
350 360 370 380 390
pF1KB7 SPPGP-NCQFLGGDHYSPLLPN-QYPVPSRFYPDL-----PGQAKDVV-PQAYWLGAPRD
: : . : . . . ::. .: : :. : :...:. : :: .: .
CCDS26 -PGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQ
470 480 490 500 510 520
400 410 420 430 440
pF1KB7 H---------SYEAEFRAVSMKPAFLPSAPGPT---MSYYRGQEVLAPGAGWPVAPQYPP
. :::.:. . .. : . : : : ..:: . .. ::: .:
CCDS26 QPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYY-PDPTFPAMAGWGGRGSYQR
530 540 550 560 570 580
450 460 470 480 490
pF1KB7 KMGPA-SWFRPMRTLPMEPGPGG-SEGRGPEDQGPPLVWTEIAP-IRP-ESSDSGLGEGD
::. . : :: : . :. . :. : : : : :. .:.:::. .
CCDS26 KMAAGLPWTS--RTSPTVFSEDQLSKEKVKEEIGSS--WIETPPSIKSLDSNDSGVYTSA
590 600 610 620 630
500 510 520 530
pF1KB7 SKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
::::.:: ::...:
CCDS26 CKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
640 650 660 670 680
>>CCDS63584.1 EOMES gene_id:8320|Hs109|chr3 (410 aa)
initn: 953 init1: 878 opt: 935 Z-score: 590.2 bits: 118.5 E(33420): 1.5e-26
Smith-Waterman score: 1011; 47.7% identity (68.2% similar) in 384 aa overlap (166-512:1-379)
140 150 160 170 180 190
pF1KB7 KLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQH
:::::::.. ::.::.:: .::.:::.: .
CCDS63 MFPFLSFNINGLNPTAHYNVFVEVVLADPN
10 20 30
200 210 220 230 240 250
pF1KB7 HWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVT
:::.:.:::: ::::...: ::..::::.:::::.::::::.:::::::::::::.:: :
CCDS63 HWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB7 QMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKI
::::::::::::::::::::.. : . :.:. :::.::::::::::::..::::::
CCDS63 QMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKI
100 110 120 130 140 150
320 330 340 350 360
pF1KB7 DNNPFAKGFRENFESMYTSV--DTSIPSPP-GPNC-QFLGGDHYS--PLLPNQY--PVP-
:.::::::::.:..::::. : ::: .: :.. : .:. ..:. . .:
CCDS63 DHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQ
160 170 180 190 200 210
370 380 390 400
pF1KB7 SRFY------PDL-----PGQAKDVV-PQAYWLGAPRDH---------SYEAEFRAVSMK
.:.: :. : :...:. : :: .: .. :::.:. . ..
CCDS63 ARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLL
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB7 PAFLPSAPGPT---MSYYRGQEVLAPGAGWPVAPQYPPKMGPA-SWFRPMRTLPMEPGPG
: . : : : ..:: . .. ::: .: ::. . : :: : .
CCDS63 PYGIKSLPLQTSHALGYY-PDPTFPAMAGWGGRGSYQRKMAAGLPWTS--RTSPTVFSED
280 290 300 310 320
470 480 490 500 510
pF1KB7 G-SEGRGPEDQGPPLVWTEIAP-IRP-ESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAP
:. . :. : : : : :. .:.:::. . ::::.:: ::...:
CCDS63 QLSKEKVKEEIGSS--WIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCE
330 340 350 360 370 380
520 530
pF1KB7 SPFDKEAEGQFYNYFPN
CCDS63 DINAEEYSKDTSKGMGGYYAFYTTP
390 400 410
>>CCDS13767.1 TBX1 gene_id:6899|Hs109|chr22 (495 aa)
initn: 643 init1: 253 opt: 716 Z-score: 455.6 bits: 93.9 E(33420): 4.8e-19
Smith-Waterman score: 725; 33.8% identity (54.8% similar) in 500 aa overlap (51-517:25-489)
30 40 50 60 70
pF1KB7 SDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG----GALVPAPPSRFLGAYA
:: :. :: : : ::
CCDS13 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP--------
10 20 30 40
80 90 100 110 120 130
pF1KB7 YPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVS
::: : ::. ::: . ::: : . :. : :. :: : : .. .
CCDS13 -PPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB7 GKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVL
.:. : :. . ::..::: ::::.:: :::::: .. . :..: . : ...: :
CCDS13 AKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVP
110 120 130 140 150 160
200 210 220 230 240
pF1KB7 VDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKG
::....:: .:..:. :::. . :: :.. ::::: ::.::.: ::: :::::::
CCDS13 VDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 ASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAE
.:. :.:.:.:.::::.:.: :. . : . :.:.::.: ::::::: .
CCDS13 DDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 ITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRF
:::::: .::::::::. . : :. : .: . .. :: :
CCDS13 ITQLKIASNPFAKGFRD-------CDPEDWPRNHRPGALPL----MSAFARSRNPVASPT
290 300 310 320
370 380 390 400 410
pF1KB7 YPDLPGQAKDVVPQAYWL----GAPR---DHSYEAEFRAVSMKPAF-----------LPS
:. : ::.. . :.: : .. .. : ..:.. ::.
CCDS13 QPS--GTEKDAAEARREFQRDAGGPAVLGDPAHPPQLLARVLSPSLPGAGGAGGLVPLPG
330 340 350 360 370 380
420 430 440 450 460
pF1KB7 APGPTMSYYRGQEVL-APGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGP---GGSEGRG
::: : . : ::::. :. .. : ::. . . .:.: : .:.:
CCDS13 APGGRPSPPNPELRLEAPGASEPL--HHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHG
390 400 410 420 430 440
470 480 490 500 510 520
pF1KB7 PEDQGPPLVWTEIAPIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEG
. .. : . :. : .. .. . . . . : :.: ..: :.
CCDS13 YHPHAHPH--HHHHPVSPAAAAAAAAAAAAAAANM--YSSAG--AAPPGSYDYCPR
450 460 470 480 490
530
pF1KB7 QFYNYFPN
>>CCDS11629.1 TBX4 gene_id:9496|Hs109|chr17 (545 aa)
initn: 692 init1: 268 opt: 713 Z-score: 453.2 bits: 93.6 E(33420): 6.5e-19
Smith-Waterman score: 721; 36.8% identity (59.1% similar) in 438 aa overlap (82-482:3-425)
60 70 80 90 100
pF1KB7 GSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQ-----PGE
: :. . :.: :. : : :
CCDS11 MLQDKGLSESEEAFRAPGPALGEASAANAPEP
10 20 30
110 120 130 140 150 160
pF1KB7 GYAAPDPRA---GLYPGPREDYALPAGLEVSGK-LRVALNNHLLWSKFNQHQTEMIITKQ
. ::: . : ::: : . :. : . . ..:.:... ::.::.. :::::::
CCDS11 ALAAPGLSGAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKA
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 GRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVH
:::::: . :.:..: ..: ...:.: .:.:.... ..::. :::: .::: :::::
CCDS11 GRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPG-RLYVH
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 PDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEA
:::: :::::::: ::: :::::::. . :.:.:.::::::::::...... .
CCDS11 PDSPATGAHWMRQLVSFQKLKLTNNHL---DPFGHIILNSMHKYQPRLHIVKADENNAFG
160 170 180 190 200
290 300 310 320 330
pF1KB7 ACN-ASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFES----------M
. : : ::.: ::.::.::.::: .::::::.::::::::: . .:
CCDS11 SKNTAFCTHVFP--ETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKE
210 220 230 240 250 260
340 350 360 370 380 390
pF1KB7 YTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRFYPDLPGQAKDVVPQAYWLGA-P
: .. :: . :. . .::: .. . ... . .... . :: :.. :
CCDS11 YPVISKSIMRQRLISPQLSATPDVGPLLGTHQAL-QHYQHENGAHSQLAEPQDLPLSTFP
270 280 290 300 310 320
400 410 420 430
pF1KB7 --RDHS--YEAEFRA-------VSMKPAFL--PSAPGPTMSYYRGQEVLAPGAGWPVAPQ
:: : :. : . : ..: ::. : :.:. : ..:.
CCDS11 TQRDSSLFYHCLKRRDGTRHLDLPCKRSYLEAPSSVGEDH-YFRSPP---PYDQQMLSPS
330 340 350 360 370 380
440 450 460 470 480 490
pF1KB7 YPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPL---VWTEIAPIRPESSDSGLGE
: .. : . : : .: . : ::: .:: ..:
CCDS11 YCSEVTPREACMYSGSGPEIAGVSGVDDLPP----PPLSCNMWTSVSPYTSYSVQTMETV
390 400 410 420 430
500 510 520 530
pF1KB7 GDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
CCDS11 PYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQSQVRERGPSASFPRERGL
440 450 460 470 480 490
>>CCDS82180.1 TBX4 gene_id:9496|Hs109|chr17 (546 aa)
initn: 692 init1: 268 opt: 713 Z-score: 453.2 bits: 93.6 E(33420): 6.5e-19
Smith-Waterman score: 721; 36.6% identity (58.0% similar) in 445 aa overlap (82-482:3-426)
60 70 80 90 100
pF1KB7 GSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQ-----PGE
: :. . :.: :. : : :
CCDS82 MLQDKGLSESEEAFRAPGPALGEASAANAPEP
10 20 30
110 120 130 140 150 160
pF1KB7 GYAAPDPRA---GLYPGPREDYALPAGLEVSGK-LRVALNNHLLWSKFNQHQTEMIITKQ
. ::: . : ::: : . :. : . . ..:.:... ::.::.. :::::::
CCDS82 ALAAPGLSGAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKA
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 GRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVH
:::::: . :.:..: ..: ...:.: .:.:.... ..::. :::: .::: :::::
CCDS82 GRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPG-RLYVH
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 PDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEA
:::: :::::::: ::: :::::::. . :.:.:.::::::::::...... .
CCDS82 PDSPATGAHWMRQLVSFQKLKLTNNHL---DPFGHIILNSMHKYQPRLHIVKADENNAFG
160 170 180 190 200
290 300 310 320 330 340
pF1KB7 ACN-ASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPS
. : : ::.: ::.::.::.::: .::::::.::::::::: . .: : .
CCDS82 SKNTAFCTHVFP--ETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDS-----DLRVAR
210 220 230 240 250 260
350 360 370 380 390 400
pF1KB7 PPGPNCQFLGGDHYSPLLPNQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRA
: . .: :.. .. . :.: . . :: : : . ...: ..
CCDS82 --------LQSKEY-PVISKSIMRQRLISPQL-SATPDVGPLLGTHQALQHYQHENGAHS
270 280 290 300 310
410 420 430 440
pF1KB7 VSMKPAFLPSAPGPTMS----YYRGQEVLAPGA---GWPVAPQY---PPKMGPASWFR--
.: :: . ::. .:. . : :. : .: : ..: .::
CCDS82 QLAEPQDLPLSTFPTQRDSSLFYHCLKRRADGTRHLDLPCKRSYLEAPSSVGEDHYFRSP
320 330 340 350 360 370
450 460 470 480
pF1KB7 -PMRTLPMEPG------PGGS---EGRGPEDQG---------PPL---VWTEIAPIRPES
:. . :. : . : ::: : ::: .:: ..:
CCDS82 PPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTSYS
380 390 400 410 420 430
490 500 510 520 530
pF1KB7 SDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
CCDS82 VQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQSQVRERGPSAS
440 450 460 470 480 490
>>CCDS13765.1 TBX1 gene_id:6899|Hs109|chr22 (372 aa)
initn: 613 init1: 253 opt: 697 Z-score: 445.6 bits: 91.6 E(33420): 1.7e-18
Smith-Waterman score: 697; 43.6% identity (63.1% similar) in 287 aa overlap (51-326:25-297)
30 40 50 60 70
pF1KB7 SDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG----GALVPAPPSRFLGAYA
:: :. :: : : ::
CCDS13 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP--------
10 20 30 40
80 90 100 110 120 130
pF1KB7 YPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVS
::: : ::. ::: . ::: : . :. : :. :: : : .. .
CCDS13 -PPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB7 GKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVL
.:. : :. . ::..::: ::::.:: :::::: .. . :..: . : ...: :
CCDS13 AKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVP
110 120 130 140 150 160
200 210 220 230 240
pF1KB7 VDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKG
::....:: .:..:. :::. . :: :.. ::::: ::.::.: ::: :::::::
CCDS13 VDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 ASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAE
.:. :.:.:.:.::::.:.: :. . : . :.:.::.: ::::::: .
CCDS13 DDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 ITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRF
:::::: .::::::::.
CCDS13 ITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVT
290 300 310 320 330 340
>>CCDS13766.1 TBX1 gene_id:6899|Hs109|chr22 (398 aa)
initn: 613 init1: 253 opt: 697 Z-score: 445.2 bits: 91.7 E(33420): 1.8e-18
Smith-Waterman score: 697; 43.6% identity (63.1% similar) in 287 aa overlap (51-326:25-297)
30 40 50 60 70
pF1KB7 SDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG----GALVPAPPSRFLGAYA
:: :. :: : : ::
CCDS13 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP--------
10 20 30 40
80 90 100 110 120 130
pF1KB7 YPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVS
::: : ::. ::: . ::: : . :. : :. :: : : .. .
CCDS13 -PPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB7 GKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVL
.:. : :. . ::..::: ::::.:: :::::: .. . :..: . : ...: :
CCDS13 AKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVP
110 120 130 140 150 160
200 210 220 230 240
pF1KB7 VDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKG
::....:: .:..:. :::. . :: :.. ::::: ::.::.: ::: :::::::
CCDS13 VDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 ASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAE
.:. :.:.:.:.::::.:.: :. . : . :.:.::.: ::::::: .
CCDS13 DDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 ITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRF
:::::: .::::::::.
CCDS13 ITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGGHV
290 300 310 320 330 340
535 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:47:17 2019 done: Thu Oct 24 21:47:18 2019
Total Scan time: 1.790 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]