Result of FASTA (ccds) for pF1KB7819
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7819, 535 aa
  1>>>pF1KB7819     535 - 535 aa - 535 aa
Library: human.CCDS.faa
  18921897 residues in 33420 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.4241+/-0.000928; mu= 1.9577+/- 0.056
 mean_var=268.9630+/-54.668, 0's: 0 Z-trim(115.0): 32  B-trim: 162 in 1/50
 Lambda= 0.078204
 statistics sampled from 15777 (15806) to 15777 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.473), width:  16
 Scan time:  1.790

The best scores are:                                      opt bits E(33420)
CCDS11514.1 TBX21 gene_id:30009|Hs109|chr17        ( 535) 3821 444.2 1.8e-124
CCDS63585.1 EOMES gene_id:8320|Hs109|chr3          ( 705) 1145 142.4 1.7e-33
CCDS33310.1 TBR1 gene_id:10716|Hs109|chr2          ( 682) 1127 140.4 6.7e-33
CCDS2646.1 EOMES gene_id:8320|Hs109|chr3           ( 686) 1083 135.4 2.1e-31
CCDS63584.1 EOMES gene_id:8320|Hs109|chr3          ( 410)  935 118.5 1.5e-26
CCDS13767.1 TBX1 gene_id:6899|Hs109|chr22          ( 495)  716 93.9 4.8e-19
CCDS11629.1 TBX4 gene_id:9496|Hs109|chr17          ( 545)  713 93.6 6.5e-19
CCDS82180.1 TBX4 gene_id:9496|Hs109|chr17          ( 546)  713 93.6 6.5e-19
CCDS13765.1 TBX1 gene_id:6899|Hs109|chr22          ( 372)  697 91.6 1.7e-18
CCDS13766.1 TBX1 gene_id:6899|Hs109|chr22          ( 398)  697 91.7 1.8e-18
CCDS9173.1 TBX5 gene_id:6910|Hs109|chr12           ( 518)  685 90.4 5.6e-18
CCDS9174.1 TBX5 gene_id:6910|Hs109|chr12           ( 468)  682 90.0 6.6e-18
CCDS11627.2 TBX2 gene_id:6909|Hs109|chr17          ( 712)  679 89.9 1.1e-17
CCDS10670.1 TBX6 gene_id:6911|Hs109|chr16          ( 436)  663 87.9 2.8e-17
CCDS9175.1 TBX3 gene_id:6926|Hs109|chr12           ( 723)  642 85.7 2.1e-16
CCDS31621.1 TBX10 gene_id:347853|Hs109|chr11       ( 385)  634 84.5 2.4e-16
CCDS34495.1 TBX18 gene_id:9096|Hs109|chr6          ( 607)  636 84.9 2.9e-16
CCDS55960.1 MGA gene_id:23269|Hs109|chr15          (2856)  624 84.2 2.3e-15
CCDS55959.1 MGA gene_id:23269|Hs109|chr15          (3065)  624 84.2 2.5e-15
CCDS81360.1 TBX15 gene_id:6913|Hs109|chr1          ( 602)  582 78.8   2e-14
CCDS14445.1 TBX22 gene_id:50945|Hs109|chrX         ( 520)  578 78.3 2.4e-14
CCDS43568.1 TBX20 gene_id:57057|Hs109|chr7         ( 447)  573 77.7 3.2e-14
CCDS30816.1 TBX15 gene_id:6913|Hs109|chr1          ( 496)  568 77.2 5.1e-14
CCDS1272.1 TBX19 gene_id:9095|Hs109|chr1           ( 448)  537 73.7 5.4e-13
CCDS59045.1 TBXT gene_id:6862|Hs109|chr6           ( 377)  492 68.5 1.6e-11
CCDS5290.1 TBXT gene_id:6862|Hs109|chr6            ( 435)  491 68.5 1.9e-11


>>CCDS11514.1 TBX21 gene_id:30009|Hs109|chr17             (535 aa)
 initn: 3821 init1: 3821 opt: 3821  Z-score: 2348.4  bits: 444.2 E(33420): 1.8e-124
Smith-Waterman score: 3821; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535)

               10        20        30        40        50        60
pF1KB7 MGIVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MGIVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 SHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 KLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 AVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 NQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 RGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEI
              430       440       450       460       470       480

              490       500       510       520       530     
pF1KB7 APIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 APIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
              490       500       510       520       530     

>>CCDS63585.1 EOMES gene_id:8320|Hs109|chr3               (705 aa)
 initn: 1143 init1: 1006 opt: 1145  Z-score: 715.1  bits: 142.4 E(33420): 1.7e-33
Smith-Waterman score: 1225; 44.5% identity (63.1% similar) in 539 aa overlap (34-512:143-674)

            10        20        30        40                  50   
pF1KB7 VEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDAD----------ERRGGGS
                                     ::.   :: : ..          .  .:. 
CCDS63 ELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAP
            120       130       140       150       160       170  

              60            70        80        90        100      
pF1KB7 LGS--PYPGGALVPA----PPSRFLGAYAYPPRPQAAGFPGAGE-SFPPPADAEGYQPGE
        :   : :.::  :     ::. : .:   : : : .  ::::  :    ... :  :: 
CCDS63 HGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFG--PGAGAGSGAGGSSGGGGGPGT
            180       190       200         210       220       230

         110       120         130          140       150       160
pF1KB7 -GYAAPDPRAGLYPGPREDYALPA--GLEVSG---KLRVALNNHLLWSKFNQHQTEMIIT
         :.   :  : :::     .  .  :: : :   . .: : :. :: ::..::::::::
CCDS63 YQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT
              240       250       260       270       280       290

              170       180       190       200       210       220
pF1KB7 KQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLY
       ::::::::::::.. ::.::.:: .::.:::.: .:::.:.:::: ::::...: ::..:
CCDS63 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMY
              300       310       320       330       340       350

              230       240       250       260       270       280
pF1KB7 VHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEP
       :::.:::::.::::::.:::::::::::::.:: :::::::::::::::::::::..   
CCDS63 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV
              360       370       380       390       400       410

              290       300       310       320       330          
pF1KB7 EAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSV--DTS
       :   . :.:. :::.::::::::::::..:::::::.::::::::.:..::::.   :  
CCDS63 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRL
              420       430       440       450       460       470

      340         350         360          370                  380
pF1KB7 IPSPP-GPNC-QFLGGDHYS--PLLPNQY--PVP-SRFY------PDL-----PGQAKDV
        :::  .:   :.. : .:.   ..:. .   .: .:.:      :.      : :...:
CCDS63 TPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEV
              480       490       500       510       520       530

               390                400       410          420       
pF1KB7 V-PQAYWLGAPRDH---------SYEAEFRAVSMKPAFLPSAPGPT---MSYYRGQEVLA
       . :   :: .: ..         :::.:. . .. :  . : :  :   ..::  . .. 
CCDS63 ANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYY-PDPTFP
              540       550       560       570       580          

       430       440        450       460        470       480     
pF1KB7 PGAGWPVAPQYPPKMGPA-SWFRPMRTLPMEPGPGG-SEGRGPEDQGPPLVWTEIAP-IR
         :::    .:  ::. .  :    :: :   .    :. .  :. :    : :  : :.
CCDS63 AMAGWGGRGSYQRKMAAGLPWTS--RTSPTVFSEDQLSKEKVKEEIGSS--WIETPPSIK
     590       600       610         620       630         640     

           490       500       510       520       530             
pF1KB7 P-ESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN        
         .:.:::.  .  ::::.::  ::...:                               
CCDS63 SLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
         650       660       670       680       690       700     

>>CCDS33310.1 TBR1 gene_id:10716|Hs109|chr2               (682 aa)
 initn: 1077 init1: 1025 opt: 1127  Z-score: 704.3  bits: 140.4 E(33420): 6.7e-33
Smith-Waterman score: 1142; 42.8% identity (64.6% similar) in 495 aa overlap (57-527:125-588)

         30        40        50        60        70        80      
pF1KB7 PGADPQHRYFYPEPGAQDADERRGGGSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGF
                                     ::::    :: :.  .:.   : :   :  
CCDS33 HSFDGSAADRYLLSQSSQPQSAATAPSAMFPYPGQHG-PAHPAFSIGS---PSR-YMAHH
          100       110       120       130        140             

             90       100       110       120        130       140 
pF1KB7 P----GAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG-PREDYALPAGLEVSGKLRVAL
       :    :: .:.   .. .:: :  ::  :.  .  : : :  ...      : :: .: :
CCDS33 PVITNGAYNSLLSNSSPQGY-PTAGYPYPQQYGHSYQGAPFYQFSSTQPGLVPGKAQVYL
     150       160        170       180       190       200        

             150       160       170       180       190       200 
pF1KB7 NNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQS
        :. :: ::..::::::::::::::::::::...::.::.:: .::::.:.: .:::.:.
CCDS33 CNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWRFQG
      210       220       230       240       250       260        

             210       220       230       240       250       260 
pF1KB7 GKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQ
       :::: ::::. .. :::.:.:::::::::::::::.::::::::::::::::  ::.:::
CCDS33 GKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQMVVLQ
      270       280       290       300       310       320        

             270       280       290       300       310       320 
pF1KB7 SLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFA
       ::::::::::.::::.   : . . . .. ::: ::::::::::::..:::::::.::::
CCDS33 SLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFA
      330       340       350       360       370       380        

             330         340        350          360          370  
pF1KB7 KGFRENFESMYTSVDTS--IPSP-PGPNCQFLGGDHYS---PLLPNQYP---VPSRFYPD
       ::::.:....::. : .   :::  .:  :.. : .:.    .: .:.    . .::.: 
CCDS33 KGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMAGSFLQDQFVSNYAKARFHPG
      390       400       410       420       430       440        

                380       390       400       410       420        
pF1KB7 L---PGQAKD-VVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYYR--GQEVL
           :: . :  ::..  : .:.    .::           :.::.:   .    .... 
CCDS33 AGAGPGPGTDRSVPHTNGLLSPQ----QAE----------DPGAPSPQRWFVTPANNRLD
      450       460       470                     480       490    

        430       440       450         460       470       480    
pF1KB7 APGAGWPVAPQYPPKMGPASWFRP--MRTLPMEPGPGGSEGRGPEDQGPPLVWTEIAPIR
         .... .: ..  . .    .    ...::..   .:  ::     . :  :   .: .
CCDS33 FAASAYDTATDFAGNAATLLSYAAAGVKALPLQA--AGCTGRPLGYYADPSGWGARSPPQ
          500       510       520         530       540       550  

          490       500        510       520        530            
pF1KB7 PESSDSGLGEGDSKRRRVSP-YPSSGDSSSPAGAPSPF-DKEAEGQFYNYFPN       
         .. ::          : : .:.:. ...  .. .:.  .::::               
CCDS33 YCGTKSG---------SVLPCWPNSAAAAARMAGANPYLGEEAEGLAAERSPLPPGAAED
                     560       570       580       590       600   

CCDS33 AKPKDLSDSSWIETPSSIKSIDSSDSGIYEQAKRRRISPADTPVSESSSPLKSEVLAQRD
           610       620       630       640       650       660   

>>CCDS2646.1 EOMES gene_id:8320|Hs109|chr3                (686 aa)
 initn: 1137 init1: 972 opt: 1083  Z-score: 677.5  bits: 135.4 E(33420): 2.1e-31
Smith-Waterman score: 1190; 44.3% identity (62.2% similar) in 526 aa overlap (34-512:143-655)

            10        20        30        40                  50   
pF1KB7 VEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDAD----------ERRGGGS
                                     ::.   :: : ..          .  .:. 
CCDS26 ELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAP
            120       130       140       150       160       170  

              60            70        80        90        100      
pF1KB7 LGS--PYPGGALVPA----PPSRFLGAYAYPPRPQAAGFPGAGE-SFPPPADAEGYQPGE
        :   : :.::  :     ::. : .:   : : : .  ::::  :    ... :  :: 
CCDS26 HGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFG--PGAGAGSGAGGSSGGGGGPGT
            180       190       200         210       220       230

         110       120         130          140       150       160
pF1KB7 -GYAAPDPRAGLYPGPREDYALPA--GLEVSG---KLRVALNNHLLWSKFNQHQTEMIIT
         :.   :  : :::     .  .  :: : :   . .: : :. :: ::..::::::::
CCDS26 YQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT
              240       250       260       270       280       290

              170       180       190       200       210       220
pF1KB7 KQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLY
       ::::::::::::.. ::.::.:: .::.:::.: .:::.:.:::: ::::...: ::..:
CCDS26 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMY
              300       310       320       330       340       350

              230       240       250       260       270       280
pF1KB7 VHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEP
       :::.:::::.::::::.:::::::::::::.:: :::::::::::::::::::::..   
CCDS26 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV
              360       370       380       390       400       410

              290       300       310       320       330       340
pF1KB7 EAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIP
       :   . :.:. :::.::::::::::::..:::::::.::::::::.:..: .  :     
CCDS26 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSSHQIV-----
              420       430       440       450       460          

               350       360        370            380        390  
pF1KB7 SPPGP-NCQFLGGDHYSPLLPN-QYPVPSRFYPDL-----PGQAKDVV-PQAYWLGAPRD
        : :  . : .  . .   ::. .:    :  :.      : :...:. :   :: .: .
CCDS26 -PGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQ
          470       480       490       500       510       520    

                     400       410          420       430       440
pF1KB7 H---------SYEAEFRAVSMKPAFLPSAPGPT---MSYYRGQEVLAPGAGWPVAPQYPP
       .         :::.:. . .. :  . : :  :   ..::  . ..   :::    .:  
CCDS26 QPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYY-PDPTFPAMAGWGGRGSYQR
          530       540       550       560        570       580   

               450       460        470       480         490      
pF1KB7 KMGPA-SWFRPMRTLPMEPGPGG-SEGRGPEDQGPPLVWTEIAP-IRP-ESSDSGLGEGD
       ::. .  :    :: :   .    :. .  :. :    : :  : :.  .:.:::.  . 
CCDS26 KMAAGLPWTS--RTSPTVFSEDQLSKEKVKEEIGSS--WIETPPSIKSLDSNDSGVYTSA
           590         600       610         620       630         

        500       510       520       530             
pF1KB7 SKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN        
        ::::.::  ::...:                               
CCDS26 CKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
     640       650       660       670       680      

>>CCDS63584.1 EOMES gene_id:8320|Hs109|chr3               (410 aa)
 initn: 953 init1: 878 opt: 935  Z-score: 590.2  bits: 118.5 E(33420): 1.5e-26
Smith-Waterman score: 1011; 47.7% identity (68.2% similar) in 384 aa overlap (166-512:1-379)

         140       150       160       170       180       190     
pF1KB7 KLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQH
                                     :::::::.. ::.::.:: .::.:::.: .
CCDS63                               MFPFLSFNINGLNPTAHYNVFVEVVLADPN
                                             10        20        30

         200       210       220       230       240       250     
pF1KB7 HWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVT
       :::.:.:::: ::::...: ::..::::.:::::.::::::.:::::::::::::.:: :
CCDS63 HWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNT
               40        50        60        70        80        90

         260       270       280       290       300       310     
pF1KB7 QMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKI
       ::::::::::::::::::::..   :   . :.:. :::.::::::::::::..::::::
CCDS63 QMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKI
              100       110       120       130       140       150

         320       330         340         350         360         
pF1KB7 DNNPFAKGFRENFESMYTSV--DTSIPSPP-GPNC-QFLGGDHYS--PLLPNQY--PVP-
       :.::::::::.:..::::.   :   :::  .:   :.. : .:.   ..:. .   .: 
CCDS63 DHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQ
              160       170       180       190       200       210

        370                  380        390                400     
pF1KB7 SRFY------PDL-----PGQAKDVV-PQAYWLGAPRDH---------SYEAEFRAVSMK
       .:.:      :.      : :...:. :   :: .: ..         :::.:. . .. 
CCDS63 ARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLL
              220       230       240       250       260       270

         410          420       430       440        450       460 
pF1KB7 PAFLPSAPGPT---MSYYRGQEVLAPGAGWPVAPQYPPKMGPA-SWFRPMRTLPMEPGPG
       :  . : :  :   ..::  . ..   :::    .:  ::. .  :    :: :   .  
CCDS63 PYGIKSLPLQTSHALGYY-PDPTFPAMAGWGGRGSYQRKMAAGLPWTS--RTSPTVFSED
              280        290       300       310         320       

              470       480         490       500       510        
pF1KB7 G-SEGRGPEDQGPPLVWTEIAP-IRP-ESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAP
         :. .  :. :    : :  : :.  .:.:::.  .  ::::.::  ::...:      
CCDS63 QLSKEKVKEEIGSS--WIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCE
       330       340         350       360       370       380     

      520       530             
pF1KB7 SPFDKEAEGQFYNYFPN        
                                
CCDS63 DINAEEYSKDTSKGMGGYYAFYTTP
         390       400       410

>>CCDS13767.1 TBX1 gene_id:6899|Hs109|chr22               (495 aa)
 initn: 643 init1: 253 opt: 716  Z-score: 455.6  bits: 93.9 E(33420): 4.8e-19
Smith-Waterman score: 725; 33.8% identity (54.8% similar) in 500 aa overlap (51-517:25-489)

               30        40        50        60            70      
pF1KB7 SDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG----GALVPAPPSRFLGAYA
                                     ::  :.  ::    :   : ::        
CCDS13       MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP--------
                     10        20        30        40              

         80          90       100       110       120       130    
pF1KB7 YPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVS
        :::  : ::. :::  . :::  :  . :. : :.        ::     :  : .. .
CCDS13 -PPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN
          50        60         70        80        90       100    

             140       150       160       170       180       190 
pF1KB7 GKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVL
       .:.    : :. . ::..:::  ::::.:: :::::: ..  . :..: . : ...: : 
CCDS13 AKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVP
          110       120       130       140       150       160    

               200       210       220       230       240         
pF1KB7 VDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKG
       ::....::  .:..:.  :::. . :: :.. :::::  ::.::.: ::: :::::::  
CCDS13 VDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLL
          170       180       190        200       210       220   

     250       260       270       280       290       300         
pF1KB7 ASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAE
        .:.    :.:.:.:.::::.:.: :.  .        : . :.:.::.: ::::::: .
CCDS13 DDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
              230       240       250       260       270       280

     310       320       330       340       350       360         
pF1KB7 ITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRF
       :::::: .::::::::.           . :    :.   :    .: .  .. :: :  
CCDS13 ITQLKIASNPFAKGFRD-------CDPEDWPRNHRPGALPL----MSAFARSRNPVASPT
              290              300       310           320         

     370       380           390          400                  410 
pF1KB7 YPDLPGQAKDVVPQAYWL----GAPR---DHSYEAEFRAVSMKPAF-----------LPS
        :.  :  ::..     .    :.:    : ..  .. :  ..:..           ::.
CCDS13 QPS--GTEKDAAEARREFQRDAGGPAVLGDPAHPPQLLARVLSPSLPGAGGAGGLVPLPG
     330         340       350       360       370       380       

             420        430       440       450       460          
pF1KB7 APGPTMSYYRGQEVL-APGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGP---GGSEGRG
       :::   :    .  : ::::. :.  .. :   ::. .  .     .:.:    : .:.:
CCDS13 APGGRPSPPNPELRLEAPGASEPL--HHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHG
       390       400       410         420       430       440     

       470       480       490       500       510       520       
pF1KB7 PEDQGPPLVWTEIAPIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEG
        . .. :    .  :. : .. .. . . .    .  : :.:  ..: :.          
CCDS13 YHPHAHPH--HHHHPVSPAAAAAAAAAAAAAAANM--YSSAG--AAPPGSYDYCPR    
         450         460       470         480         490         

       530     
pF1KB7 QFYNYFPN

>>CCDS11629.1 TBX4 gene_id:9496|Hs109|chr17               (545 aa)
 initn: 692 init1: 268 opt: 713  Z-score: 453.2  bits: 93.6 E(33420): 6.5e-19
Smith-Waterman score: 721; 36.8% identity (59.1% similar) in 438 aa overlap (82-482:3-425)

              60        70        80        90       100           
pF1KB7 GSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQ-----PGE
                                     :  :.  . :.:  :. : :       :  
CCDS11                             MLQDKGLSESEEAFRAPGPALGEASAANAPEP
                                           10        20        30  

        110          120       130        140       150       160  
pF1KB7 GYAAPDPRA---GLYPGPREDYALPAGLEVSGK-LRVALNNHLLWSKFNQHQTEMIITKQ
       . :::   .   :  :::  : .  :. : . . ..:.:... ::.::..  ::::::: 
CCDS11 ALAAPGLSGAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKA
             40        50        60        70        80        90  

            170       180       190       200       210       220  
pF1KB7 GRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVH
       ::::::  .  :.:..: ..: ...:.: .:.:.... ..::.  :::: .::: :::::
CCDS11 GRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPG-RLYVH
            100       110       120       130       140        150 

            230       240       250       260       270       280  
pF1KB7 PDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEA
       :::: :::::::: ::: :::::::.    .    :.:.:.::::::::::......  .
CCDS11 PDSPATGAHWMRQLVSFQKLKLTNNHL---DPFGHIILNSMHKYQPRLHIVKADENNAFG
             160       170          180       190       200        

             290       300       310       320       330           
pF1KB7 ACN-ASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFES----------M
       . : :  ::.:   ::.::.::.::: .::::::.::::::::: . .:           
CCDS11 SKNTAFCTHVFP--ETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKE
      210       220         230       240       250       260      

             340       350       360       370       380        390
pF1KB7 YTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRFYPDLPGQAKDVVPQAYWLGA-P
       :  .. ::      . :. .    .::: ..  . ...  .  .... . ::   :.. :
CCDS11 YPVISKSIMRQRLISPQLSATPDVGPLLGTHQAL-QHYQHENGAHSQLAEPQDLPLSTFP
        270       280       290       300        310       320     

                  400                410       420       430       
pF1KB7 --RDHS--YEAEFRA-------VSMKPAFL--PSAPGPTMSYYRGQEVLAPGAGWPVAPQ
         :: :  :.   :        .  : ..:  ::. :    :.:.     :     ..:.
CCDS11 TQRDSSLFYHCLKRRDGTRHLDLPCKRSYLEAPSSVGEDH-YFRSPP---PYDQQMLSPS
         330       340       350       360        370          380 

       440       450       460       470          480       490    
pF1KB7 YPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPL---VWTEIAPIRPESSDSGLGE
       :  .. :        . :   : .: .   :    :::   .:: ..:            
CCDS11 YCSEVTPREACMYSGSGPEIAGVSGVDDLPP----PPLSCNMWTSVSPYTSYSVQTMETV
             390       400       410           420       430       

          500       510       520       530                        
pF1KB7 GDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN                   
                                                                   
CCDS11 PYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQSQVRERGPSASFPRERGL
       440       450       460       470       480       490       

>>CCDS82180.1 TBX4 gene_id:9496|Hs109|chr17               (546 aa)
 initn: 692 init1: 268 opt: 713  Z-score: 453.2  bits: 93.6 E(33420): 6.5e-19
Smith-Waterman score: 721; 36.6% identity (58.0% similar) in 445 aa overlap (82-482:3-426)

              60        70        80        90       100           
pF1KB7 GSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQ-----PGE
                                     :  :.  . :.:  :. : :       :  
CCDS82                             MLQDKGLSESEEAFRAPGPALGEASAANAPEP
                                           10        20        30  

        110          120       130        140       150       160  
pF1KB7 GYAAPDPRA---GLYPGPREDYALPAGLEVSGK-LRVALNNHLLWSKFNQHQTEMIITKQ
       . :::   .   :  :::  : .  :. : . . ..:.:... ::.::..  ::::::: 
CCDS82 ALAAPGLSGAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKA
             40        50        60        70        80        90  

            170       180       190       200       210       220  
pF1KB7 GRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVH
       ::::::  .  :.:..: ..: ...:.: .:.:.... ..::.  :::: .::: :::::
CCDS82 GRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPG-RLYVH
            100       110       120       130       140        150 

            230       240       250       260       270       280  
pF1KB7 PDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEA
       :::: :::::::: ::: :::::::.    .    :.:.:.::::::::::......  .
CCDS82 PDSPATGAHWMRQLVSFQKLKLTNNHL---DPFGHIILNSMHKYQPRLHIVKADENNAFG
             160       170          180       190       200        

             290       300       310       320       330       340 
pF1KB7 ACN-ASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPS
       . : :  ::.:   ::.::.::.::: .::::::.::::::::: . .:     :  .  
CCDS82 SKNTAFCTHVFP--ETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDS-----DLRVAR
      210       220         230       240       250            260 

             350       360       370       380       390       400 
pF1KB7 PPGPNCQFLGGDHYSPLLPNQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRA
               : . .: :.. ..      . :.: . . :: :      : . ...:   ..
CCDS82 --------LQSKEY-PVISKSIMRQRLISPQL-SATPDVGPLLGTHQALQHYQHENGAHS
                      270       280        290       300       310 

             410           420       430             440           
pF1KB7 VSMKPAFLPSAPGPTMS----YYRGQEVLAPGA---GWPVAPQY---PPKMGPASWFR--
          .:  :: .  ::.     .:.  .  : :.     :   .:   : ..:   .::  
CCDS82 QLAEPQDLPLSTFPTQRDSSLFYHCLKRRADGTRHLDLPCKRSYLEAPSSVGEDHYFRSP
             320       330       340       350       360       370 

      450             460          470                   480       
pF1KB7 -PMRTLPMEPG------PGGS---EGRGPEDQG---------PPL---VWTEIAPIRPES
        :.    . :.      :  .    : :::  :         :::   .:: ..:     
CCDS82 PPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTSYS
             380       390       400       410       420       430 

       490       500       510       520       530                 
pF1KB7 SDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN            
                                                                   
CCDS82 VQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQSQVRERGPSAS
             440       450       460       470       480       490 

>>CCDS13765.1 TBX1 gene_id:6899|Hs109|chr22               (372 aa)
 initn: 613 init1: 253 opt: 697  Z-score: 445.6  bits: 91.6 E(33420): 1.7e-18
Smith-Waterman score: 697; 43.6% identity (63.1% similar) in 287 aa overlap (51-326:25-297)

               30        40        50        60            70      
pF1KB7 SDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG----GALVPAPPSRFLGAYA
                                     ::  :.  ::    :   : ::        
CCDS13       MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP--------
                     10        20        30        40              

         80          90       100       110       120       130    
pF1KB7 YPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVS
        :::  : ::. :::  . :::  :  . :. : :.        ::     :  : .. .
CCDS13 -PPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN
          50        60         70        80        90       100    

             140       150       160       170       180       190 
pF1KB7 GKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVL
       .:.    : :. . ::..:::  ::::.:: :::::: ..  . :..: . : ...: : 
CCDS13 AKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVP
          110       120       130       140       150       160    

               200       210       220       230       240         
pF1KB7 VDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKG
       ::....::  .:..:.  :::. . :: :.. :::::  ::.::.: ::: :::::::  
CCDS13 VDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLL
          170       180       190        200       210       220   

     250       260       270       280       290       300         
pF1KB7 ASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAE
        .:.    :.:.:.:.::::.:.: :.  .        : . :.:.::.: ::::::: .
CCDS13 DDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
              230       240       250       260       270       280

     310       320       330       340       350       360         
pF1KB7 ITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRF
       :::::: .::::::::.                                           
CCDS13 ITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVT
              290       300       310       320       330       340

>>CCDS13766.1 TBX1 gene_id:6899|Hs109|chr22               (398 aa)
 initn: 613 init1: 253 opt: 697  Z-score: 445.2  bits: 91.7 E(33420): 1.8e-18
Smith-Waterman score: 697; 43.6% identity (63.1% similar) in 287 aa overlap (51-326:25-297)

               30        40        50        60            70      
pF1KB7 SDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG----GALVPAPPSRFLGAYA
                                     ::  :.  ::    :   : ::        
CCDS13       MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP--------
                     10        20        30        40              

         80          90       100       110       120       130    
pF1KB7 YPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVS
        :::  : ::. :::  . :::  :  . :. : :.        ::     :  : .. .
CCDS13 -PPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN
          50        60         70        80        90       100    

             140       150       160       170       180       190 
pF1KB7 GKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVL
       .:.    : :. . ::..:::  ::::.:: :::::: ..  . :..: . : ...: : 
CCDS13 AKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVP
          110       120       130       140       150       160    

               200       210       220       230       240         
pF1KB7 VDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKG
       ::....::  .:..:.  :::. . :: :.. :::::  ::.::.: ::: :::::::  
CCDS13 VDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLL
          170       180       190        200       210       220   

     250       260       270       280       290       300         
pF1KB7 ASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAE
        .:.    :.:.:.:.::::.:.: :.  .        : . :.:.::.: ::::::: .
CCDS13 DDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
              230       240       250       260       270       280

     310       320       330       340       350       360         
pF1KB7 ITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRF
       :::::: .::::::::.                                           
CCDS13 ITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGGHV
              290       300       310       320       330       340




535 residues in 1 query   sequences
18921897 residues in 33420 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:47:17 2019 done: Thu Oct 24 21:47:18 2019
 Total Scan time:  1.790 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
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