FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7820, 599 aa 1>>>pF1KB7820 599 - 599 aa - 599 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.6109+/-0.000354; mu= -0.3563+/- 0.022 mean_var=225.3314+/-46.635, 0's: 0 Z-trim(120.9): 36 B-trim: 0 in 0/59 Lambda= 0.085440 statistics sampled from 36808 (36850) to 36808 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.432), width: 16 Scan time: 11.890 The best scores are: opt bits E(85289) NP_444511 (OMIM: 300608) dachshund homolog 2 isofo ( 599) 3929 497.3 6.2e-140 XP_011529150 (OMIM: 300608) PREDICTED: dachshund h ( 584) 3817 483.5 8.7e-136 XP_011529149 (OMIM: 300608) PREDICTED: dachshund h ( 594) 3131 398.9 2.5e-110 XP_011529148 (OMIM: 300608) PREDICTED: dachshund h ( 609) 3131 398.9 2.6e-110 NP_001132987 (OMIM: 300608) dachshund homolog 2 is ( 432) 2810 359.3 1.6e-98 XP_016884744 (OMIM: 300608) PREDICTED: dachshund h ( 586) 2761 353.3 1.3e-96 NP_001132986 (OMIM: 300608) dachshund homolog 2 is ( 571) 2649 339.5 1.9e-92 XP_016884745 (OMIM: 300608) PREDICTED: dachshund h ( 571) 2649 339.5 1.9e-92 XP_016884743 (OMIM: 300608) PREDICTED: dachshund h ( 596) 1963 254.9 5.5e-67 XP_011533242 (OMIM: 603803) PREDICTED: dachshund h ( 614) 1367 181.5 7.4e-45 XP_011533241 (OMIM: 603803) PREDICTED: dachshund h ( 758) 1367 181.5 8.8e-45 NP_542937 (OMIM: 603803) dachshund homolog 1 isofo ( 706) 943 129.2 4.5e-29 XP_016875885 (OMIM: 603803) PREDICTED: dachshund h ( 417) 768 107.5 9e-23 XP_011533244 (OMIM: 603803) PREDICTED: dachshund h ( 365) 754 105.8 2.7e-22 XP_011533243 (OMIM: 603803) PREDICTED: dachshund h ( 379) 705 99.7 1.8e-20 NP_542938 (OMIM: 603803) dachshund homolog 1 isofo ( 558) 688 97.8 1.1e-19 NP_004383 (OMIM: 603803) dachshund homolog 1 isofo ( 504) 687 97.6 1.1e-19 >>NP_444511 (OMIM: 300608) dachshund homolog 2 isoform a (599 aa) initn: 3929 init1: 3929 opt: 3929 Z-score: 2633.2 bits: 497.3 E(85289): 6.2e-140 Smith-Waterman score: 3929; 100.0% identity (100.0% similar) in 599 aa overlap (1-599:1-599) 10 20 30 40 50 60 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 490 500 510 520 530 540 550 560 570 580 590 pF1KB7 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA 550 560 570 580 590 >>XP_011529150 (OMIM: 300608) PREDICTED: dachshund homol (584 aa) initn: 3817 init1: 3817 opt: 3817 Z-score: 2558.8 bits: 483.5 E(85289): 8.7e-136 Smith-Waterman score: 3817; 100.0% identity (100.0% similar) in 583 aa overlap (1-583:1-583) 10 20 30 40 50 60 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 490 500 510 520 530 540 550 560 570 580 590 pF1KB7 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA ::::::::::::::::::::::::::::::::::::::::::: XP_011 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQA 550 560 570 580 >>XP_011529149 (OMIM: 300608) PREDICTED: dachshund homol (594 aa) initn: 3076 init1: 3076 opt: 3131 Z-score: 2101.7 bits: 398.9 E(85289): 2.5e-110 Smith-Waterman score: 3787; 98.3% identity (98.3% similar) in 593 aa overlap (1-583:1-593) 10 20 30 40 50 60 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 370 380 390 400 410 420 430 440 450 460 470 pF1KB7 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQ----------GLLKVAL ::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_011 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQVNNISINKINGLLKVAL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB7 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB7 EALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCL ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQA 550 560 570 580 590 pF1KB7 EMAQQLYSA >>XP_011529148 (OMIM: 300608) PREDICTED: dachshund homol (609 aa) initn: 3076 init1: 3076 opt: 3131 Z-score: 2101.5 bits: 398.9 E(85289): 2.6e-110 Smith-Waterman score: 3899; 98.4% identity (98.4% similar) in 609 aa overlap (1-599:1-609) 10 20 30 40 50 60 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 370 380 390 400 410 420 430 440 450 460 470 pF1KB7 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQ----------GLLKVAL ::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_011 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQVNNISINKINGLLKVAL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB7 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB7 EALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCL 550 560 570 580 590 600 pF1KB7 EMAQQLYSA ::::::::: XP_011 EMAQQLYSA >>NP_001132987 (OMIM: 300608) dachshund homolog 2 isofor (432 aa) initn: 2810 init1: 2810 opt: 2810 Z-score: 1889.9 bits: 359.3 E(85289): 1.6e-98 Smith-Waterman score: 2810; 100.0% identity (100.0% similar) in 432 aa overlap (168-599:1-432) 140 150 160 170 180 190 pF1KB7 QPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPPKRSLGVLQENARLL :::::::::::::::::::::::::::::: NP_001 MTRKQAVNSSRPGRPPKRSLGVLQENARLL 10 20 30 200 210 220 230 240 250 pF1KB7 THAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNT 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB7 GGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLNPLQQNHLLTNRLDLPFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLNPLQQNHLLTNRLDLPFM 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB7 MMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTSVIKERIPESPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTSVIKERIPESPSP 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB7 APSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQA 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB7 LPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREI 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB7 RENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGL 340 350 360 370 380 390 560 570 580 590 pF1KB7 RMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA :::::::::::::::::::::::::::::::::::::::::: NP_001 RMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA 400 410 420 430 >>XP_016884744 (OMIM: 300608) PREDICTED: dachshund homol (586 aa) initn: 2761 init1: 2761 opt: 2761 Z-score: 1855.3 bits: 353.3 E(85289): 1.3e-96 Smith-Waterman score: 3810; 97.8% identity (97.8% similar) in 599 aa overlap (1-599:1-586) 10 20 30 40 50 60 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG :::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNA-------------SSRPG 130 140 150 160 190 200 210 220 230 240 pF1KB7 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB7 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB7 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 470 480 490 500 510 520 550 560 570 580 590 pF1KB7 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA 530 540 550 560 570 580 >>NP_001132986 (OMIM: 300608) dachshund homolog 2 isofor (571 aa) initn: 2649 init1: 2649 opt: 2649 Z-score: 1780.8 bits: 339.5 E(85289): 1.9e-92 Smith-Waterman score: 3698; 97.8% identity (97.8% similar) in 583 aa overlap (1-583:1-570) 10 20 30 40 50 60 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG :::::::::::::::::::::::::::::::::::::::::: ::::: NP_001 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNA-------------SSRPG 130 140 150 160 190 200 210 220 230 240 pF1KB7 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB7 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB7 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 470 480 490 500 510 520 550 560 570 580 590 pF1KB7 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA ::::::::::::::::::::::::::::::::::::::::::: NP_001 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQA 530 540 550 560 570 >>XP_016884745 (OMIM: 300608) PREDICTED: dachshund homol (571 aa) initn: 2649 init1: 2649 opt: 2649 Z-score: 1780.8 bits: 339.5 E(85289): 1.9e-92 Smith-Waterman score: 3698; 97.8% identity (97.8% similar) in 583 aa overlap (1-583:1-570) 10 20 30 40 50 60 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG :::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNA-------------SSRPG 130 140 150 160 190 200 210 220 230 240 pF1KB7 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB7 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB7 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 470 480 490 500 510 520 550 560 570 580 590 pF1KB7 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA ::::::::::::::::::::::::::::::::::::::::::: XP_016 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQA 530 540 550 560 570 >>XP_016884743 (OMIM: 300608) PREDICTED: dachshund homol (596 aa) initn: 2110 init1: 1908 opt: 1963 Z-score: 1323.6 bits: 254.9 E(85289): 5.5e-67 Smith-Waterman score: 3780; 96.2% identity (96.2% similar) in 609 aa overlap (1-599:1-596) 10 20 30 40 50 60 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG :::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNA-------------SSRPG 130 140 150 160 190 200 210 220 230 240 pF1KB7 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 350 360 370 380 390 400 430 440 450 460 470 pF1KB7 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQ----------GLLKVAL ::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_016 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQVNNISINKINGLLKVAL 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB7 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ 470 480 490 500 510 520 540 550 560 570 580 590 pF1KB7 EALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCL 530 540 550 560 570 580 pF1KB7 EMAQQLYSA ::::::::: XP_016 EMAQQLYSA 590 >>XP_011533242 (OMIM: 603803) PREDICTED: dachshund homol (614 aa) initn: 1400 init1: 593 opt: 1367 Z-score: 926.3 bits: 181.5 E(85289): 7.4e-45 Smith-Waterman score: 1501; 55.0% identity (74.8% similar) in 453 aa overlap (4-445:148-554) 10 20 30 pF1KB7 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPR :.: :..::... : . ..:.:::: XP_011 GGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPS 120 130 140 150 160 170 40 50 60 70 80 90 pF1KB7 EPPRLTPNMINSFVVNNHSNSAGGGGRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQ : . ::. .:::.:::..: ::::: ..: ::::::: XP_011 -PVENTPQ-----------------------NNECKMVDLRGAKVASFTVEGCELICLPQ 180 190 200 210 100 110 120 130 140 150 pF1KB7 VFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFE .::::::::::::::::::::::.:.::::.:::::::::::::::::::::::.::::: XP_011 AFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFE 220 230 240 250 260 270 160 170 180 190 200 210 pF1KB7 TLFTDCTNARRKRQMTRKQAVNSSRPGRPPKRSLGVLQ-ENARLLTHAVPGLLSPGLITP ::..::::: ::::::::::. .: . ::.... :.::::.:::.: : XP_011 TLYNDCTNA-------------SSRPGRPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPP 280 290 300 310 320 220 230 240 250 260 pF1KB7 TGITAAA----------MAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSES ::.:::: .:::::..:.:: ::.. .....:.:..:: :.::..:.:.. XP_011 TGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSDG 330 340 350 360 370 380 270 280 290 300 310 320 pF1KB7 SWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHP ::::. . : . ::: .:.: . : .. . :: :::.::: : :.::::::::: XP_011 SWDKETLPSS-PSQGPQASITHPRMPGARSLPLSHPLNHLQQSHLLPNGLELPFMMMPHP 390 400 410 420 430 330 340 350 360 370 380 pF1KB7 LLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLE :.:::::::::.:::.:::::.::::::::::..:: ::. :::::::.:.::::::::: XP_011 LIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLE 440 450 460 470 480 490 390 400 410 420 430 440 pF1KB7 ENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGF :..::::. ::: ::::::::.. . .: ::. .. :. :. : . : . XP_011 EGRRPGSHPSSHRSSSVSSSPARTESSSDR-------IPVHQNGLSMNQMLMGLS-PNVL 500 510 520 530 540 550 450 460 470 480 490 500 pF1KB7 PGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE ::: XP_011 PGPKEGDLAGHDMGHESKRMHIEKVHIILTRIQLDFTKNTGLNMHKRLQCGMCADSSVSS 560 570 580 590 600 610 599 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:50:44 2016 done: Sat Nov 5 09:50:46 2016 Total Scan time: 11.890 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]