FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7823, 536 aa 1>>>pF1KB7823 536 - 536 aa - 536 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.9917+/-0.000348; mu= 8.3318+/- 0.022 mean_var=197.7500+/-39.500, 0's: 0 Z-trim(120.4): 9 B-trim: 0 in 0/58 Lambda= 0.091204 statistics sampled from 35633 (35645) to 35633 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.418), width: 16 Scan time: 9.430 The best scores are: opt bits E(85289) NP_036377 (OMIM: 603055) SNW domain-containing pro ( 536) 3585 484.2 4.2e-136 NP_001305773 (OMIM: 603055) SNW domain-containing ( 571) 3129 424.3 5e-118 XP_005267470 (OMIM: 603055) PREDICTED: SNW domain- ( 430) 2270 311.1 4.3e-84 >>NP_036377 (OMIM: 603055) SNW domain-containing protein (536 aa) initn: 3585 init1: 3585 opt: 3585 Z-score: 2564.5 bits: 484.2 E(85289): 4.2e-136 Smith-Waterman score: 3585; 100.0% identity (100.0% similar) in 536 aa overlap (1-536:1-536) 10 20 30 40 50 60 pF1KB7 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 GFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSG 430 440 450 460 470 480 490 500 510 520 530 pF1KB7 SDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE 490 500 510 520 530 >>NP_001305773 (OMIM: 603055) SNW domain-containing prot (571 aa) initn: 3129 init1: 3129 opt: 3129 Z-score: 2239.9 bits: 424.3 E(85289): 5e-118 Smith-Waterman score: 3129; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB7 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 GFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSG ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRCQAIQLNFS 430 440 450 460 470 480 490 500 510 520 530 pF1KB7 SDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE NP_001 VYTGESKVVHSFFSFSLDLFPTRSFLVQTVDREAEKDQCSLRKILLVWTSFWKKPNSMVA 490 500 510 520 530 540 >>XP_005267470 (OMIM: 603055) PREDICTED: SNW domain-cont (430 aa) initn: 2270 init1: 2270 opt: 2270 Z-score: 1630.7 bits: 311.1 E(85289): 4.3e-84 Smith-Waterman score: 2270; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB7 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKARE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRR :::::::::::::::::::::::::::::::::::::::::::: XP_005 AVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKGRNFREMKIGISVKLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS XP_005 LSVFLILGLPMKFSMTKGSSTNPRVWTVDLQVEKMKFIMFMIKPGEVVKIWPRVFIGPVK 370 380 390 400 410 420 536 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:28:29 2016 done: Fri Nov 4 22:28:30 2016 Total Scan time: 9.430 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]