FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7834, 581 aa
1>>>pF1KB7834 581 - 581 aa - 581 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0505+/-0.000431; mu= 0.0440+/- 0.027
mean_var=156.5758+/-33.353, 0's: 0 Z-trim(116.9): 136 B-trim: 1538 in 2/52
Lambda= 0.102497
statistics sampled from 28356 (28499) to 28356 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.334), width: 16
Scan time: 9.070
The best scores are: opt bits E(85289)
NP_001186084 (OMIM: 609880) histone acetyltransfer ( 581) 3913 590.9 3.9e-168
NP_001186087 (OMIM: 609880) histone acetyltransfer ( 442) 2655 404.8 3e-112
NP_001186086 (OMIM: 609880) histone acetyltransfer ( 501) 2639 402.5 1.7e-111
NP_008998 (OMIM: 609880) histone acetyltransferase ( 611) 2519 384.7 4.6e-106
NP_001186085 (OMIM: 609880) histone acetyltransfer ( 472) 2441 373.2 1.1e-102
XP_011522537 (OMIM: 609880) PREDICTED: histone ace ( 328) 2228 341.7 2.3e-93
NP_001292807 (OMIM: 601408,616268) histone acetylt ( 815) 1210 191.2 1.1e-47
NP_006757 (OMIM: 601408,616268) histone acetyltran (2004) 1210 191.3 2.6e-47
XP_016869353 (OMIM: 601408,616268) PREDICTED: hist (2004) 1210 191.3 2.6e-47
XP_016869352 (OMIM: 601408,616268) PREDICTED: hist (2004) 1210 191.3 2.6e-47
NP_001243397 (OMIM: 603736,605880,606170) histone (1890) 1208 191.0 3e-47
XP_016871494 (OMIM: 603736,605880,606170) PREDICTE (1890) 1208 191.0 3e-47
NP_001243398 (OMIM: 603736,605880,606170) histone (1781) 1203 190.3 4.7e-47
XP_016871497 (OMIM: 603736,605880,606170) PREDICTE (1781) 1203 190.3 4.7e-47
XP_016871496 (OMIM: 603736,605880,606170) PREDICTE (1781) 1203 190.3 4.7e-47
XP_016871495 (OMIM: 603736,605880,606170) PREDICTE (1781) 1203 190.3 4.7e-47
XP_016871492 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47
XP_016871491 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47
XP_016871489 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47
XP_005269721 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47
XP_016871490 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47
NP_036462 (OMIM: 603736,605880,606170) histone ace (2073) 1203 190.3 5.4e-47
NP_115564 (OMIM: 609912) histone acetyltransferase ( 458) 1164 184.4 7.2e-46
XP_011542961 (OMIM: 601408,616268) PREDICTED: hist (2041) 1171 185.5 1.4e-45
XP_011542958 (OMIM: 601408,616268) PREDICTED: hist (2048) 1171 185.5 1.4e-45
XP_011542960 (OMIM: 601408,616268) PREDICTED: hist (2048) 1171 185.5 1.4e-45
XP_011542959 (OMIM: 601408,616268) PREDICTED: hist (2048) 1171 185.5 1.4e-45
XP_011544273 (OMIM: 609912) PREDICTED: histone ace ( 300) 1151 182.4 1.9e-45
XP_011544272 (OMIM: 609912) PREDICTED: histone ace ( 300) 1151 182.4 1.9e-45
NP_892003 (OMIM: 609912) histone acetyltransferase ( 467) 1096 174.3 7.9e-43
NP_874368 (OMIM: 601409) histone acetyltransferase ( 461) 1060 169.0 3.1e-41
NP_001193762 (OMIM: 601409) histone acetyltransfer ( 494) 1060 169.0 3.3e-41
NP_006379 (OMIM: 601409) histone acetyltransferase ( 513) 1060 169.0 3.4e-41
XP_006718484 (OMIM: 601409) PREDICTED: histone ace ( 522) 1060 169.0 3.5e-41
NP_874369 (OMIM: 601409) histone acetyltransferase ( 546) 1060 169.0 3.6e-41
XP_016871498 (OMIM: 603736,605880,606170) PREDICTE (1727) 473 82.3 1.4e-14
XP_016871493 (OMIM: 603736,605880,606170) PREDICTE (2019) 473 82.3 1.6e-14
>>NP_001186084 (OMIM: 609880) histone acetyltransferase (581 aa)
initn: 3913 init1: 3913 opt: 3913 Z-score: 3139.6 bits: 590.9 E(85289): 3.9e-168
Smith-Waterman score: 3913; 100.0% identity (100.0% similar) in 581 aa overlap (1-581:1-581)
10 20 30 40 50 60
pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG
490 500 510 520 530 540
550 560 570 580
pF1KB7 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
:::::::::::::::::::::::::::::::::::::::::
NP_001 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
550 560 570 580
>>NP_001186087 (OMIM: 609880) histone acetyltransferase (442 aa)
initn: 2639 init1: 2639 opt: 2655 Z-score: 2136.2 bits: 404.8 E(85289): 3e-112
Smith-Waterman score: 2685; 76.1% identity (76.1% similar) in 581 aa overlap (1-581:1-442)
10 20 30 40 50 60
pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQ------
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD
NP_001 ------------------------------------------------------------
130 140 150 160 170 180
pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN
NP_001 ------------------------------------------------------------
190 200 210 220 230 240
pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------GHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK
60 70 80 90 100
250 260 270 280 290 300
pF1KB7 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI
110 120 130 140 150 160
310 320 330 340 350 360
pF1KB7 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW
170 180 190 200 210 220
370 380 390 400 410 420
pF1KB7 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD
230 240 250 260 270 280
430 440 450 460 470 480
pF1KB7 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP
290 300 310 320 330 340
490 500 510 520 530 540
pF1KB7 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG
350 360 370 380 390 400
550 560 570 580
pF1KB7 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
:::::::::::::::::::::::::::::::::::::::::
NP_001 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
410 420 430 440
>>NP_001186086 (OMIM: 609880) histone acetyltransferase (501 aa)
initn: 3345 init1: 2635 opt: 2639 Z-score: 2122.6 bits: 402.5 E(85289): 1.7e-111
Smith-Waterman score: 3189; 86.2% identity (86.2% similar) in 581 aa overlap (1-581:1-501)
10 20 30 40 50 60
pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDR-------
70 80 90 100 110
130 140 150 160 170 180
pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN
NP_001 ------------------------------------------------------------
190 200 210 220 230 240
pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------GHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK
120 130 140 150 160
250 260 270 280 290 300
pF1KB7 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB7 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB7 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD
290 300 310 320 330 340
430 440 450 460 470 480
pF1KB7 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP
350 360 370 380 390 400
490 500 510 520 530 540
pF1KB7 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG
410 420 430 440 450 460
550 560 570 580
pF1KB7 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
:::::::::::::::::::::::::::::::::::::::::
NP_001 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
470 480 490 500
>>NP_008998 (OMIM: 609880) histone acetyltransferase KAT (611 aa)
initn: 2435 init1: 2435 opt: 2519 Z-score: 2025.2 bits: 384.7 E(85289): 4.6e-106
Smith-Waterman score: 3843; 95.1% identity (95.1% similar) in 611 aa overlap (1-581:1-611)
10 20 30 40 50 60
pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN
130 140 150 160 170 180
190 200 210 220
pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECK-------------------
:::::::::::::::::::::::::::::::::::::::::
NP_008 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQ
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 -----------APTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 DDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB7 RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB7 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB7 YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB7 IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP
550 560 570 580 590 600
580
pF1KB7 SCLKWTPPKGT
:::::::::::
NP_008 SCLKWTPPKGT
610
>>NP_001186085 (OMIM: 609880) histone acetyltransferase (472 aa)
initn: 2759 init1: 2435 opt: 2441 Z-score: 1964.7 bits: 373.2 E(85289): 1.1e-102
Smith-Waterman score: 2615; 72.3% identity (72.3% similar) in 611 aa overlap (1-581:1-472)
10 20 30 40 50 60
pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQ------
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD
NP_001 ------------------------------------------------------------
130 140 150 160 170 180
pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN
NP_001 ------------------------------------------------------------
190 200 210 220
pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECK-------------------
::::::::::::::::::::::::::::
NP_001 -------------GHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQ
60 70 80 90 100
230 240 250 260 270
pF1KB7 -----------APTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB7 LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA
170 180 190 200 210 220
340 350 360 370 380 390
pF1KB7 RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN
230 240 250 260 270 280
400 410 420 430 440 450
pF1KB7 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ
290 300 310 320 330 340
460 470 480 490 500 510
pF1KB7 YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS
350 360 370 380 390 400
520 530 540 550 560 570
pF1KB7 IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP
410 420 430 440 450 460
580
pF1KB7 SCLKWTPPKGT
:::::::::::
NP_001 SCLKWTPPKGT
470
>>XP_011522537 (OMIM: 609880) PREDICTED: histone acetylt (328 aa)
initn: 2228 init1: 2228 opt: 2228 Z-score: 1797.2 bits: 341.7 E(85289): 2.3e-93
Smith-Waterman score: 2228; 100.0% identity (100.0% similar) in 328 aa overlap (254-581:1-328)
230 240 250 260 270 280
pF1KB7 TERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRA
::::::::::::::::::::::::::::::
XP_011 MEHRQTYGNTREPLLENLTSEYDLDLFRRA
10 20 30
290 300 310 320 330 340
pF1KB7 QARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLK
40 50 60 70 80 90
350 360 370 380 390 400
pF1KB7 YMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKT
100 110 120 130 140 150
410 420 430 440 450 460
pF1KB7 LYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDF
160 170 180 190 200 210
470 480 490 500 510 520
pF1KB7 SYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPV
220 230 240 250 260 270
530 540 550 560 570 580
pF1KB7 DIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
280 290 300 310 320
>>NP_001292807 (OMIM: 601408,616268) histone acetyltrans (815 aa)
initn: 1182 init1: 1127 opt: 1210 Z-score: 977.0 bits: 191.2 E(85289): 1.1e-47
Smith-Waterman score: 1210; 50.7% identity (74.7% similar) in 375 aa overlap (206-577:410-778)
180 190 200 210 220 230
pF1KB7 HESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVA
:.: . . : : :: : . :.:.
NP_001 EEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEV-VDYSEQY-
380 390 400 410 420 430
240 250 260 270 280 290
pF1KB7 ELRKKRNSGLS-KEQKEKYMEHRQTYGNTREPLL--ENLTSEYDLDLFRRAQARASEDLE
..::. : : .. .. . ...: :. ... .: :..::: : .: :.
NP_001 RIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQEQA---LQ
440 450 460 470 480 490
300 310 320 330 340 350
pF1KB7 KLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILR
:. . : ..: ::.::. ::: ::::.::.:: .::.::::::::::.:::.
NP_001 KVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQ
500 510 520 530 540 550
360 370 380 390 400 410
pF1KB7 RHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFL
.:: :: : :::..:::::..::::::::. . :::::::::::::::::::::::::::
NP_001 QHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFL
560 570 580 590 600 610
420 430 440 450 460 470
pF1KB7 FYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEE
:::.:. : ::::.:::::::. .::::::. .:::.:.:::..:::::::::: :
NP_001 FYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREG
620 630 640 650 660 670
480 490 500 510 520 530
pF1KB7 KVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQAL
..::::.:::::: .:: .::: :.:. :.. . :.::::..:. :.. : ::.:::. :
NP_001 QAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHL
680 690 700 710 720 730
540 550 560 570 580
pF1KB7 QMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
.:: . . . ....:. ::.. .:: . . .:: ::.:::
NP_001 RMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEE
740 750 760 770 780 790
NP_001 AEEGENEEPQCQERELEISVRA
800 810
>>NP_006757 (OMIM: 601408,616268) histone acetyltransfer (2004 aa)
initn: 1182 init1: 1127 opt: 1210 Z-score: 970.5 bits: 191.3 E(85289): 2.6e-47
Smith-Waterman score: 1210; 50.7% identity (74.7% similar) in 375 aa overlap (206-577:410-778)
180 190 200 210 220 230
pF1KB7 HESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVA
:.: . . : : :: : . :.:.
NP_006 EEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEV-VDYSEQY-
380 390 400 410 420 430
240 250 260 270 280 290
pF1KB7 ELRKKRNSGLS-KEQKEKYMEHRQTYGNTREPLL--ENLTSEYDLDLFRRAQARASEDLE
..::. : : .. .. . ...: :. ... .: :..::: : .: :.
NP_006 RIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQEQA---LQ
440 450 460 470 480 490
300 310 320 330 340 350
pF1KB7 KLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILR
:. . : ..: ::.::. ::: ::::.::.:: .::.::::::::::.:::.
NP_006 KVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQ
500 510 520 530 540 550
360 370 380 390 400 410
pF1KB7 RHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFL
.:: :: : :::..:::::..::::::::. . :::::::::::::::::::::::::::
NP_006 QHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFL
560 570 580 590 600 610
420 430 440 450 460 470
pF1KB7 FYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEE
:::.:. : ::::.:::::::. .::::::. .:::.:.:::..:::::::::: :
NP_006 FYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREG
620 630 640 650 660 670
480 490 500 510 520 530
pF1KB7 KVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQAL
..::::.:::::: .:: .::: :.:. :.. . :.::::..:. :.. : ::.:::. :
NP_006 QAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHL
680 690 700 710 720 730
540 550 560 570 580
pF1KB7 QMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
.:: . . . ....:. ::.. .:: . . .:: ::.:::
NP_006 RMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEE
740 750 760 770 780 790
NP_006 AEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPH
800 810 820 830 840 850
>>XP_016869353 (OMIM: 601408,616268) PREDICTED: histone (2004 aa)
initn: 1182 init1: 1127 opt: 1210 Z-score: 970.5 bits: 191.3 E(85289): 2.6e-47
Smith-Waterman score: 1210; 50.7% identity (74.7% similar) in 375 aa overlap (206-577:410-778)
180 190 200 210 220 230
pF1KB7 HESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVA
:.: . . : : :: : . :.:.
XP_016 EEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEV-VDYSEQY-
380 390 400 410 420 430
240 250 260 270 280 290
pF1KB7 ELRKKRNSGLS-KEQKEKYMEHRQTYGNTREPLL--ENLTSEYDLDLFRRAQARASEDLE
..::. : : .. .. . ...: :. ... .: :..::: : .: :.
XP_016 RIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQEQA---LQ
440 450 460 470 480 490
300 310 320 330 340 350
pF1KB7 KLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILR
:. . : ..: ::.::. ::: ::::.::.:: .::.::::::::::.:::.
XP_016 KVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQ
500 510 520 530 540 550
360 370 380 390 400 410
pF1KB7 RHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFL
.:: :: : :::..:::::..::::::::. . :::::::::::::::::::::::::::
XP_016 QHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFL
560 570 580 590 600 610
420 430 440 450 460 470
pF1KB7 FYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEE
:::.:. : ::::.:::::::. .::::::. .:::.:.:::..:::::::::: :
XP_016 FYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREG
620 630 640 650 660 670
480 490 500 510 520 530
pF1KB7 KVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQAL
..::::.:::::: .:: .::: :.:. :.. . :.::::..:. :.. : ::.:::. :
XP_016 QAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHL
680 690 700 710 720 730
540 550 560 570 580
pF1KB7 QMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
.:: . . . ....:. ::.. .:: . . .:: ::.:::
XP_016 RMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEE
740 750 760 770 780 790
XP_016 AEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPH
800 810 820 830 840 850
>>XP_016869352 (OMIM: 601408,616268) PREDICTED: histone (2004 aa)
initn: 1182 init1: 1127 opt: 1210 Z-score: 970.5 bits: 191.3 E(85289): 2.6e-47
Smith-Waterman score: 1210; 50.7% identity (74.7% similar) in 375 aa overlap (206-577:410-778)
180 190 200 210 220 230
pF1KB7 HESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVA
:.: . . : : :: : . :.:.
XP_016 EEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEV-VDYSEQY-
380 390 400 410 420 430
240 250 260 270 280 290
pF1KB7 ELRKKRNSGLS-KEQKEKYMEHRQTYGNTREPLL--ENLTSEYDLDLFRRAQARASEDLE
..::. : : .. .. . ...: :. ... .: :..::: : .: :.
XP_016 RIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQEQA---LQ
440 450 460 470 480 490
300 310 320 330 340 350
pF1KB7 KLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILR
:. . : ..: ::.::. ::: ::::.::.:: .::.::::::::::.:::.
XP_016 KVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQ
500 510 520 530 540 550
360 370 380 390 400 410
pF1KB7 RHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFL
.:: :: : :::..:::::..::::::::. . :::::::::::::::::::::::::::
XP_016 QHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFL
560 570 580 590 600 610
420 430 440 450 460 470
pF1KB7 FYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEE
:::.:. : ::::.:::::::. .::::::. .:::.:.:::..:::::::::: :
XP_016 FYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREG
620 630 640 650 660 670
480 490 500 510 520 530
pF1KB7 KVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQAL
..::::.:::::: .:: .::: :.:. :.. . :.::::..:. :.. : ::.:::. :
XP_016 QAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHL
680 690 700 710 720 730
540 550 560 570 580
pF1KB7 QMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
.:: . . . ....:. ::.. .:: . . .:: ::.:::
XP_016 RMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEE
740 750 760 770 780 790
XP_016 AEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPH
800 810 820 830 840 850
581 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:24:22 2016 done: Fri Nov 4 23:24:23 2016
Total Scan time: 9.070 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]