FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7834, 581 aa 1>>>pF1KB7834 581 - 581 aa - 581 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0505+/-0.000431; mu= 0.0440+/- 0.027 mean_var=156.5758+/-33.353, 0's: 0 Z-trim(116.9): 136 B-trim: 1538 in 2/52 Lambda= 0.102497 statistics sampled from 28356 (28499) to 28356 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.334), width: 16 Scan time: 9.070 The best scores are: opt bits E(85289) NP_001186084 (OMIM: 609880) histone acetyltransfer ( 581) 3913 590.9 3.9e-168 NP_001186087 (OMIM: 609880) histone acetyltransfer ( 442) 2655 404.8 3e-112 NP_001186086 (OMIM: 609880) histone acetyltransfer ( 501) 2639 402.5 1.7e-111 NP_008998 (OMIM: 609880) histone acetyltransferase ( 611) 2519 384.7 4.6e-106 NP_001186085 (OMIM: 609880) histone acetyltransfer ( 472) 2441 373.2 1.1e-102 XP_011522537 (OMIM: 609880) PREDICTED: histone ace ( 328) 2228 341.7 2.3e-93 NP_001292807 (OMIM: 601408,616268) histone acetylt ( 815) 1210 191.2 1.1e-47 NP_006757 (OMIM: 601408,616268) histone acetyltran (2004) 1210 191.3 2.6e-47 XP_016869353 (OMIM: 601408,616268) PREDICTED: hist (2004) 1210 191.3 2.6e-47 XP_016869352 (OMIM: 601408,616268) PREDICTED: hist (2004) 1210 191.3 2.6e-47 NP_001243397 (OMIM: 603736,605880,606170) histone (1890) 1208 191.0 3e-47 XP_016871494 (OMIM: 603736,605880,606170) PREDICTE (1890) 1208 191.0 3e-47 NP_001243398 (OMIM: 603736,605880,606170) histone (1781) 1203 190.3 4.7e-47 XP_016871497 (OMIM: 603736,605880,606170) PREDICTE (1781) 1203 190.3 4.7e-47 XP_016871496 (OMIM: 603736,605880,606170) PREDICTE (1781) 1203 190.3 4.7e-47 XP_016871495 (OMIM: 603736,605880,606170) PREDICTE (1781) 1203 190.3 4.7e-47 XP_016871492 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47 XP_016871491 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47 XP_016871489 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47 XP_005269721 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47 XP_016871490 (OMIM: 603736,605880,606170) PREDICTE (2073) 1203 190.3 5.4e-47 NP_036462 (OMIM: 603736,605880,606170) histone ace (2073) 1203 190.3 5.4e-47 NP_115564 (OMIM: 609912) histone acetyltransferase ( 458) 1164 184.4 7.2e-46 XP_011542961 (OMIM: 601408,616268) PREDICTED: hist (2041) 1171 185.5 1.4e-45 XP_011542958 (OMIM: 601408,616268) PREDICTED: hist (2048) 1171 185.5 1.4e-45 XP_011542960 (OMIM: 601408,616268) PREDICTED: hist (2048) 1171 185.5 1.4e-45 XP_011542959 (OMIM: 601408,616268) PREDICTED: hist (2048) 1171 185.5 1.4e-45 XP_011544273 (OMIM: 609912) PREDICTED: histone ace ( 300) 1151 182.4 1.9e-45 XP_011544272 (OMIM: 609912) PREDICTED: histone ace ( 300) 1151 182.4 1.9e-45 NP_892003 (OMIM: 609912) histone acetyltransferase ( 467) 1096 174.3 7.9e-43 NP_874368 (OMIM: 601409) histone acetyltransferase ( 461) 1060 169.0 3.1e-41 NP_001193762 (OMIM: 601409) histone acetyltransfer ( 494) 1060 169.0 3.3e-41 NP_006379 (OMIM: 601409) histone acetyltransferase ( 513) 1060 169.0 3.4e-41 XP_006718484 (OMIM: 601409) PREDICTED: histone ace ( 522) 1060 169.0 3.5e-41 NP_874369 (OMIM: 601409) histone acetyltransferase ( 546) 1060 169.0 3.6e-41 XP_016871498 (OMIM: 603736,605880,606170) PREDICTE (1727) 473 82.3 1.4e-14 XP_016871493 (OMIM: 603736,605880,606170) PREDICTE (2019) 473 82.3 1.6e-14 >>NP_001186084 (OMIM: 609880) histone acetyltransferase (581 aa) initn: 3913 init1: 3913 opt: 3913 Z-score: 3139.6 bits: 590.9 E(85289): 3.9e-168 Smith-Waterman score: 3913; 100.0% identity (100.0% similar) in 581 aa overlap (1-581:1-581) 10 20 30 40 50 60 pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG 490 500 510 520 530 540 550 560 570 580 pF1KB7 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT ::::::::::::::::::::::::::::::::::::::::: NP_001 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT 550 560 570 580 >>NP_001186087 (OMIM: 609880) histone acetyltransferase (442 aa) initn: 2639 init1: 2639 opt: 2655 Z-score: 2136.2 bits: 404.8 E(85289): 3e-112 Smith-Waterman score: 2685; 76.1% identity (76.1% similar) in 581 aa overlap (1-581:1-442) 10 20 30 40 50 60 pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQ------ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD NP_001 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN NP_001 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------------GHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK 60 70 80 90 100 250 260 270 280 290 300 pF1KB7 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI 110 120 130 140 150 160 310 320 330 340 350 360 pF1KB7 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW 170 180 190 200 210 220 370 380 390 400 410 420 pF1KB7 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD 230 240 250 260 270 280 430 440 450 460 470 480 pF1KB7 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP 290 300 310 320 330 340 490 500 510 520 530 540 pF1KB7 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG 350 360 370 380 390 400 550 560 570 580 pF1KB7 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT ::::::::::::::::::::::::::::::::::::::::: NP_001 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT 410 420 430 440 >>NP_001186086 (OMIM: 609880) histone acetyltransferase (501 aa) initn: 3345 init1: 2635 opt: 2639 Z-score: 2122.6 bits: 402.5 E(85289): 1.7e-111 Smith-Waterman score: 3189; 86.2% identity (86.2% similar) in 581 aa overlap (1-581:1-501) 10 20 30 40 50 60 pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDR------- 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN NP_001 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------------GHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKK 120 130 140 150 160 250 260 270 280 290 300 pF1KB7 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQI 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB7 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVW 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB7 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEAD 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB7 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERP 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB7 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKG 410 420 430 440 450 460 550 560 570 580 pF1KB7 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT ::::::::::::::::::::::::::::::::::::::::: NP_001 KHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT 470 480 490 500 >>NP_008998 (OMIM: 609880) histone acetyltransferase KAT (611 aa) initn: 2435 init1: 2435 opt: 2519 Z-score: 2025.2 bits: 384.7 E(85289): 4.6e-106 Smith-Waterman score: 3843; 95.1% identity (95.1% similar) in 611 aa overlap (1-581:1-611) 10 20 30 40 50 60 pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN 130 140 150 160 170 180 190 200 210 220 pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECK------------------- ::::::::::::::::::::::::::::::::::::::::: NP_008 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQ 190 200 210 220 230 240 230 240 250 260 270 pF1KB7 -----------APTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN ::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 DDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB7 RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB7 YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB7 IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP 550 560 570 580 590 600 580 pF1KB7 SCLKWTPPKGT ::::::::::: NP_008 SCLKWTPPKGT 610 >>NP_001186085 (OMIM: 609880) histone acetyltransferase (472 aa) initn: 2759 init1: 2435 opt: 2441 Z-score: 1964.7 bits: 373.2 E(85289): 1.1e-102 Smith-Waterman score: 2615; 72.3% identity (72.3% similar) in 611 aa overlap (1-581:1-472) 10 20 30 40 50 60 pF1KB7 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQ------ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD NP_001 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB7 HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN NP_001 ------------------------------------------------------------ 190 200 210 220 pF1KB7 FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECK------------------- :::::::::::::::::::::::::::: NP_001 -------------GHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQ 60 70 80 90 100 230 240 250 260 270 pF1KB7 -----------APTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN 110 120 130 140 150 160 280 290 300 310 320 330 pF1KB7 LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA 170 180 190 200 210 220 340 350 360 370 380 390 pF1KB7 RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN 230 240 250 260 270 280 400 410 420 430 440 450 pF1KB7 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ 290 300 310 320 330 340 460 470 480 490 500 510 pF1KB7 YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS 350 360 370 380 390 400 520 530 540 550 560 570 pF1KB7 IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP 410 420 430 440 450 460 580 pF1KB7 SCLKWTPPKGT ::::::::::: NP_001 SCLKWTPPKGT 470 >>XP_011522537 (OMIM: 609880) PREDICTED: histone acetylt (328 aa) initn: 2228 init1: 2228 opt: 2228 Z-score: 1797.2 bits: 341.7 E(85289): 2.3e-93 Smith-Waterman score: 2228; 100.0% identity (100.0% similar) in 328 aa overlap (254-581:1-328) 230 240 250 260 270 280 pF1KB7 TERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRA :::::::::::::::::::::::::::::: XP_011 MEHRQTYGNTREPLLENLTSEYDLDLFRRA 10 20 30 290 300 310 320 330 340 pF1KB7 QARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLK 40 50 60 70 80 90 350 360 370 380 390 400 pF1KB7 YMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKT 100 110 120 130 140 150 410 420 430 440 450 460 pF1KB7 LYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDF 160 170 180 190 200 210 470 480 490 500 510 520 pF1KB7 SYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPV 220 230 240 250 260 270 530 540 550 560 570 580 pF1KB7 DIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT 280 290 300 310 320 >>NP_001292807 (OMIM: 601408,616268) histone acetyltrans (815 aa) initn: 1182 init1: 1127 opt: 1210 Z-score: 977.0 bits: 191.2 E(85289): 1.1e-47 Smith-Waterman score: 1210; 50.7% identity (74.7% similar) in 375 aa overlap (206-577:410-778) 180 190 200 210 220 230 pF1KB7 HESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVA :.: . . : : :: : . :.:. NP_001 EEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEV-VDYSEQY- 380 390 400 410 420 430 240 250 260 270 280 290 pF1KB7 ELRKKRNSGLS-KEQKEKYMEHRQTYGNTREPLL--ENLTSEYDLDLFRRAQARASEDLE ..::. : : .. .. . ...: :. ... .: :..::: : .: :. NP_001 RIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQEQA---LQ 440 450 460 470 480 490 300 310 320 330 340 350 pF1KB7 KLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILR :. . : ..: ::.::. ::: ::::.::.:: .::.::::::::::.:::. NP_001 KVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQ 500 510 520 530 540 550 360 370 380 390 400 410 pF1KB7 RHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFL .:: :: : :::..:::::..::::::::. . ::::::::::::::::::::::::::: NP_001 QHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFL 560 570 580 590 600 610 420 430 440 450 460 470 pF1KB7 FYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEE :::.:. : ::::.:::::::. .::::::. .:::.:.:::..:::::::::: : NP_001 FYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREG 620 630 640 650 660 670 480 490 500 510 520 530 pF1KB7 KVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQAL ..::::.:::::: .:: .::: :.:. :.. . :.::::..:. :.. : ::.:::. : NP_001 QAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHL 680 690 700 710 720 730 540 550 560 570 580 pF1KB7 QMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT .:: . . . ....:. ::.. .:: . . .:: ::.::: NP_001 RMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEE 740 750 760 770 780 790 NP_001 AEEGENEEPQCQERELEISVRA 800 810 >>NP_006757 (OMIM: 601408,616268) histone acetyltransfer (2004 aa) initn: 1182 init1: 1127 opt: 1210 Z-score: 970.5 bits: 191.3 E(85289): 2.6e-47 Smith-Waterman score: 1210; 50.7% identity (74.7% similar) in 375 aa overlap (206-577:410-778) 180 190 200 210 220 230 pF1KB7 HESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVA :.: . . : : :: : . :.:. NP_006 EEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEV-VDYSEQY- 380 390 400 410 420 430 240 250 260 270 280 290 pF1KB7 ELRKKRNSGLS-KEQKEKYMEHRQTYGNTREPLL--ENLTSEYDLDLFRRAQARASEDLE ..::. : : .. .. . ...: :. ... .: :..::: : .: :. NP_006 RIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQEQA---LQ 440 450 460 470 480 490 300 310 320 330 340 350 pF1KB7 KLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILR :. . : ..: ::.::. ::: ::::.::.:: .::.::::::::::.:::. NP_006 KVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQ 500 510 520 530 540 550 360 370 380 390 400 410 pF1KB7 RHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFL .:: :: : :::..:::::..::::::::. . ::::::::::::::::::::::::::: NP_006 QHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFL 560 570 580 590 600 610 420 430 440 450 460 470 pF1KB7 FYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEE :::.:. : ::::.:::::::. .::::::. .:::.:.:::..:::::::::: : NP_006 FYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREG 620 630 640 650 660 670 480 490 500 510 520 530 pF1KB7 KVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQAL ..::::.:::::: .:: .::: :.:. :.. . :.::::..:. :.. : ::.:::. : NP_006 QAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHL 680 690 700 710 720 730 540 550 560 570 580 pF1KB7 QMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT .:: . . . ....:. ::.. .:: . . .:: ::.::: NP_006 RMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEE 740 750 760 770 780 790 NP_006 AEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPH 800 810 820 830 840 850 >>XP_016869353 (OMIM: 601408,616268) PREDICTED: histone (2004 aa) initn: 1182 init1: 1127 opt: 1210 Z-score: 970.5 bits: 191.3 E(85289): 2.6e-47 Smith-Waterman score: 1210; 50.7% identity (74.7% similar) in 375 aa overlap (206-577:410-778) 180 190 200 210 220 230 pF1KB7 HESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVA :.: . . : : :: : . :.:. XP_016 EEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEV-VDYSEQY- 380 390 400 410 420 430 240 250 260 270 280 290 pF1KB7 ELRKKRNSGLS-KEQKEKYMEHRQTYGNTREPLL--ENLTSEYDLDLFRRAQARASEDLE ..::. : : .. .. . ...: :. ... .: :..::: : .: :. XP_016 RIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQEQA---LQ 440 450 460 470 480 490 300 310 320 330 340 350 pF1KB7 KLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILR :. . : ..: ::.::. ::: ::::.::.:: .::.::::::::::.:::. XP_016 KVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQ 500 510 520 530 540 550 360 370 380 390 400 410 pF1KB7 RHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFL .:: :: : :::..:::::..::::::::. . ::::::::::::::::::::::::::: XP_016 QHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFL 560 570 580 590 600 610 420 430 440 450 460 470 pF1KB7 FYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEE :::.:. : ::::.:::::::. .::::::. .:::.:.:::..:::::::::: : XP_016 FYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREG 620 630 640 650 660 670 480 490 500 510 520 530 pF1KB7 KVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQAL ..::::.:::::: .:: .::: :.:. :.. . :.::::..:. :.. : ::.:::. : XP_016 QAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHL 680 690 700 710 720 730 540 550 560 570 580 pF1KB7 QMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT .:: . . . ....:. ::.. .:: . . .:: ::.::: XP_016 RMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEE 740 750 760 770 780 790 XP_016 AEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPH 800 810 820 830 840 850 >>XP_016869352 (OMIM: 601408,616268) PREDICTED: histone (2004 aa) initn: 1182 init1: 1127 opt: 1210 Z-score: 970.5 bits: 191.3 E(85289): 2.6e-47 Smith-Waterman score: 1210; 50.7% identity (74.7% similar) in 375 aa overlap (206-577:410-778) 180 190 200 210 220 230 pF1KB7 HESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKAPTERQLRYKEKVA :.: . . : : :: : . :.:. XP_016 EEGYLERIDGLDFCRDSNVSLKFNKKTKGLIDGLTKFFTPSPDGRKARGEV-VDYSEQY- 380 390 400 410 420 430 240 250 260 270 280 290 pF1KB7 ELRKKRNSGLS-KEQKEKYMEHRQTYGNTREPLL--ENLTSEYDLDLFRRAQARASEDLE ..::. : : .. .. . ...: :. ... .: :..::: : .: :. XP_016 RIRKRGNRKSSTSDWPTDNQDGWDGKQENEERLFGSQEIMTEKDMELFRDIQEQA---LQ 440 450 460 470 480 490 300 310 320 330 340 350 pF1KB7 KLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILR :. . : ..: ::.::. ::: ::::.::.:: .::.::::::::::.:::. XP_016 KVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQ 500 510 520 530 540 550 360 370 380 390 400 410 pF1KB7 RHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFL .:: :: : :::..:::::..::::::::. . ::::::::::::::::::::::::::: XP_016 QHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFL 560 570 580 590 600 610 420 430 440 450 460 470 pF1KB7 FYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEE :::.:. : ::::.:::::::. .::::::. .:::.:.:::..:::::::::: : XP_016 FYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREG 620 630 640 650 660 670 480 490 500 510 520 530 pF1KB7 KVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQAL ..::::.:::::: .:: .::: :.:. :.. . :.::::..:. :.. : ::.:::. : XP_016 QAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHL 680 690 700 710 720 730 540 550 560 570 580 pF1KB7 QMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT .:: . . . ....:. ::.. .:: . . .:: ::.::: XP_016 RMLDFRSDQFVIIRREKLIQDHMAK-LQLNLRPVDVDPECLRWTPVIVSNSVVSEEEEEE 740 750 760 770 780 790 XP_016 AEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLPH 800 810 820 830 840 850 581 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:24:22 2016 done: Fri Nov 4 23:24:23 2016 Total Scan time: 9.070 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]