FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7835, 540 aa 1>>>pF1KB7835 540 - 540 aa - 540 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.6103+/-0.000428; mu= -2.1975+/- 0.027 mean_var=193.1965+/-40.109, 0's: 0 Z-trim(117.0): 45 B-trim: 1184 in 1/52 Lambda= 0.092273 statistics sampled from 28581 (28626) to 28581 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.336), width: 16 Scan time: 10.740 The best scores are: opt bits E(85289) XP_011536701 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 540) 3666 500.8 4.3e-141 NP_001186231 (OMIM: 604909) CCR4-NOT transcription ( 540) 3666 500.8 4.3e-141 NP_001186232 (OMIM: 604909) CCR4-NOT transcription ( 540) 3666 500.8 4.3e-141 NP_055330 (OMIM: 604909) CCR4-NOT transcription co ( 540) 3666 500.8 4.3e-141 XP_006719493 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 531) 3568 487.8 3.6e-137 XP_016874837 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 531) 3568 487.8 3.6e-137 XP_006719492 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 531) 3568 487.8 3.6e-137 XP_016874838 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 531) 3568 487.8 3.6e-137 XP_016874839 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 520) 3538 483.8 5.6e-136 XP_016874841 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 520) 3538 483.8 5.6e-136 XP_011536702 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 520) 3538 483.8 5.6e-136 XP_016874840 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 520) 3538 483.8 5.6e-136 XP_006719495 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 479) 2417 334.5 4.3e-91 XP_016874843 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 394) 2218 308.0 3.4e-83 XP_016874842 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 394) 2218 308.0 3.4e-83 XP_006719496 (OMIM: 604909) PREDICTED: CCR4-NOT tr ( 403) 2218 308.0 3.5e-83 >>XP_011536701 (OMIM: 604909) PREDICTED: CCR4-NOT transc (540 aa) initn: 3666 init1: 3666 opt: 3666 Z-score: 2654.1 bits: 500.8 E(85289): 4.3e-141 Smith-Waterman score: 3666; 100.0% identity (100.0% similar) in 540 aa overlap (1-540:1-540) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 490 500 510 520 530 540 >>NP_001186231 (OMIM: 604909) CCR4-NOT transcription com (540 aa) initn: 3666 init1: 3666 opt: 3666 Z-score: 2654.1 bits: 500.8 E(85289): 4.3e-141 Smith-Waterman score: 3666; 100.0% identity (100.0% similar) in 540 aa overlap (1-540:1-540) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 490 500 510 520 530 540 >>NP_001186232 (OMIM: 604909) CCR4-NOT transcription com (540 aa) initn: 3666 init1: 3666 opt: 3666 Z-score: 2654.1 bits: 500.8 E(85289): 4.3e-141 Smith-Waterman score: 3666; 100.0% identity (100.0% similar) in 540 aa overlap (1-540:1-540) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 490 500 510 520 530 540 >>NP_055330 (OMIM: 604909) CCR4-NOT transcription comple (540 aa) initn: 3666 init1: 3666 opt: 3666 Z-score: 2654.1 bits: 500.8 E(85289): 4.3e-141 Smith-Waterman score: 3666; 100.0% identity (100.0% similar) in 540 aa overlap (1-540:1-540) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 490 500 510 520 530 540 >>XP_006719493 (OMIM: 604909) PREDICTED: CCR4-NOT transc (531 aa) initn: 3567 init1: 3567 opt: 3568 Z-score: 2583.7 bits: 487.8 E(85289): 3.6e-137 Smith-Waterman score: 3568; 99.4% identity (99.6% similar) in 529 aa overlap (12-540:3-531) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :. ::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLKEVAQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 480 490 500 510 520 530 >>XP_016874837 (OMIM: 604909) PREDICTED: CCR4-NOT transc (531 aa) initn: 3567 init1: 3567 opt: 3568 Z-score: 2583.7 bits: 487.8 E(85289): 3.6e-137 Smith-Waterman score: 3568; 99.4% identity (99.6% similar) in 529 aa overlap (12-540:3-531) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :. ::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLKEVAQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 480 490 500 510 520 530 >>XP_006719492 (OMIM: 604909) PREDICTED: CCR4-NOT transc (531 aa) initn: 3567 init1: 3567 opt: 3568 Z-score: 2583.7 bits: 487.8 E(85289): 3.6e-137 Smith-Waterman score: 3568; 99.4% identity (99.6% similar) in 529 aa overlap (12-540:3-531) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :. ::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLKEVAQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 480 490 500 510 520 530 >>XP_016874838 (OMIM: 604909) PREDICTED: CCR4-NOT transc (531 aa) initn: 3567 init1: 3567 opt: 3568 Z-score: 2583.7 bits: 487.8 E(85289): 3.6e-137 Smith-Waterman score: 3568; 99.4% identity (99.6% similar) in 529 aa overlap (12-540:3-531) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :. ::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLKEVAQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 480 490 500 510 520 530 >>XP_016874839 (OMIM: 604909) PREDICTED: CCR4-NOT transc (520 aa) initn: 3538 init1: 3538 opt: 3538 Z-score: 2562.3 bits: 483.8 E(85289): 5.6e-136 Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 520 aa overlap (21-540:1-520) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :::::::::::::::::::::::::::::::::::::::: XP_016 MFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 470 480 490 500 510 520 >>XP_016874841 (OMIM: 604909) PREDICTED: CCR4-NOT transc (520 aa) initn: 3538 init1: 3538 opt: 3538 Z-score: 2562.3 bits: 483.8 E(85289): 5.6e-136 Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 520 aa overlap (21-540:1-520) 10 20 30 40 50 60 pF1KB7 MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA :::::::::::::::::::::::::::::::::::::::: XP_016 MFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLA 10 20 30 40 70 80 90 100 110 120 pF1KB7 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRRE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKS 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGL 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSE 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB7 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWIT 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB7 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF 470 480 490 500 510 520 540 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:32:59 2016 done: Fri Nov 4 22:33:00 2016 Total Scan time: 10.740 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]