FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7838, 614 aa 1>>>pF1KB7838 614 - 614 aa - 614 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.0357+/-0.000388; mu= -4.6851+/- 0.024 mean_var=309.0121+/-64.874, 0's: 0 Z-trim(123.9): 404 B-trim: 2164 in 2/56 Lambda= 0.072960 statistics sampled from 44158 (44582) to 44158 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.523), width: 16 Scan time: 12.010 The best scores are: opt bits E(85289) NP_068370 (OMIM: 602408) nuclear receptor subfamil ( 614) 4164 451.6 3.6e-126 NP_005117 (OMIM: 602304) nuclear receptor subfamil ( 579) 1722 194.6 8.1e-49 NP_001138897 (OMIM: 602304) nuclear receptor subfa ( 504) 1699 192.1 3.9e-48 XP_006713514 (OMIM: 602304) PREDICTED: nuclear rec ( 448) 1134 132.6 2.8e-30 XP_011532146 (OMIM: 125853,601487,601665,604367,60 ( 250) 468 62.3 2.2e-09 NP_001317544 (OMIM: 125853,601487,601665,604367,60 ( 250) 468 62.3 2.2e-09 XP_011532145 (OMIM: 125853,601487,601665,604367,60 ( 278) 468 62.4 2.4e-09 XP_011532144 (OMIM: 125853,601487,601665,604367,60 ( 445) 468 62.5 3.6e-09 XP_011532143 (OMIM: 125853,601487,601665,604367,60 ( 477) 468 62.5 3.8e-09 NP_005028 (OMIM: 125853,601487,601665,604367,60933 ( 477) 468 62.5 3.8e-09 NP_619725 (OMIM: 125853,601487,601665,604367,60933 ( 477) 468 62.5 3.8e-09 NP_619726 (OMIM: 125853,601487,601665,604367,60933 ( 477) 468 62.5 3.8e-09 NP_056953 (OMIM: 125853,601487,601665,604367,60933 ( 505) 468 62.5 4e-09 NP_599023 (OMIM: 600825) nuclear receptor ROR-alph ( 523) 462 61.9 6.3e-09 NP_803184 (OMIM: 600409) peroxisome proliferator-a ( 361) 449 60.4 1.2e-08 XP_016866464 (OMIM: 600409) PREDICTED: peroxisome ( 365) 449 60.4 1.2e-08 XP_016866461 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 XP_016866460 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 NP_001165289 (OMIM: 600409) peroxisome proliferato ( 441) 449 60.5 1.4e-08 XP_006715183 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 XP_011513012 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 XP_011513011 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 XP_016866462 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 NP_006229 (OMIM: 600409) peroxisome proliferator-a ( 441) 449 60.5 1.4e-08 XP_011513009 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 XP_016866463 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 XP_005249250 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 XP_006715186 (OMIM: 600409) PREDICTED: peroxisome ( 441) 449 60.5 1.4e-08 XP_006724333 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 XP_011528545 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 XP_005261713 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 XP_011528544 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 XP_011528542 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 XP_011528541 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 XP_011528543 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 XP_006724332 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 XP_005261712 (OMIM: 170998) PREDICTED: peroxisome ( 468) 446 60.2 1.9e-08 NP_005027 (OMIM: 170998) peroxisome proliferator-a ( 468) 446 60.2 1.9e-08 NP_001001928 (OMIM: 170998) peroxisome proliferato ( 468) 446 60.2 1.9e-08 NP_002934 (OMIM: 600825) nuclear receptor ROR-alph ( 548) 446 60.2 2.1e-08 XP_011520176 (OMIM: 600825) PREDICTED: nuclear rec ( 525) 442 59.8 2.7e-08 NP_001165290 (OMIM: 600409) peroxisome proliferato ( 402) 438 59.3 2.9e-08 XP_016877955 (OMIM: 600825) PREDICTED: nuclear rec ( 460) 438 59.4 3.3e-08 XP_011520177 (OMIM: 600825) PREDICTED: nuclear rec ( 504) 439 59.5 3.3e-08 XP_011520179 (OMIM: 600825) PREDICTED: nuclear rec ( 467) 438 59.4 3.3e-08 NP_599024 (OMIM: 600825) nuclear receptor ROR-alph ( 468) 438 59.4 3.3e-08 XP_005254641 (OMIM: 600825) PREDICTED: nuclear rec ( 477) 438 59.4 3.4e-08 NP_599022 (OMIM: 600825) nuclear receptor ROR-alph ( 556) 438 59.4 3.8e-08 NP_001001523 (OMIM: 602943,616622) nuclear recepto ( 497) 434 59.0 4.7e-08 NP_005051 (OMIM: 602943,616622) nuclear receptor R ( 518) 434 59.0 4.8e-08 >>NP_068370 (OMIM: 602408) nuclear receptor subfamily 1 (614 aa) initn: 4164 init1: 4164 opt: 4164 Z-score: 2386.2 bits: 451.6 E(85289): 3.6e-126 Smith-Waterman score: 4164; 100.0% identity (100.0% similar) in 614 aa overlap (1-614:1-614) 10 20 30 40 50 60 pF1KB7 MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 TQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 NITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 NRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 NRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 PTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 TYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 TYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 APSSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 APSSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 NMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 NMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 TAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 TAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNN 550 560 570 580 590 600 610 pF1KB7 MHSEKLLSFRVDAQ :::::::::::::: NP_068 MHSEKLLSFRVDAQ 610 >>NP_005117 (OMIM: 602304) nuclear receptor subfamily 1 (579 aa) initn: 1836 init1: 910 opt: 1722 Z-score: 997.4 bits: 194.6 E(85289): 8.1e-49 Smith-Waterman score: 1783; 51.3% identity (72.5% similar) in 614 aa overlap (9-611:4-577) 10 20 30 40 50 60 pF1KB7 MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL :.::::.::.::.:. .:: : .:..:..:::: ... :. : : ... NP_005 MEVNAGGVIAYISSSSSA---SSPASCHSEGSENSFQSSSSSVPSS-PNSSNSDT 10 20 30 40 50 70 80 90 100 110 pF1KB7 TQDPARS-FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKST . .: . ...: :..: : ..:.::. :: .:: NP_005 NGNPKNGDLANIEGILKNDRIDCSMKTSKSSA--------PGM-------------TKSH 60 70 80 90 120 130 140 150 160 170 pF1KB7 SNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVR :..::..:::::::::::::::::::::::::::::::::::::::::.:::::::::.: NP_005 SGVTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMR 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 INRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-LANNQLSSQCPLE .::::::::::::::::::::::::::::::::::::: ::::::. . :.:.:.. . NP_005 MNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQND 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB7 TSPTQHP-TPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSP-SPEPTVEDVISQVARAH : .: : : . : : :. :. :: : . . :.::..:.::: NP_005 TLVEHHEQTALPAQEQLRPKP---------QLEQENIKSSSPPSSDFAKEEVIGMVTRAH 220 230 240 250 260 300 310 320 330 340 350 pF1KB7 REIFTYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLA-AQRHNEAL .. : : ... .: ... ... : . ... : . ... . .:.: : NP_005 KDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDHCGNGLSSHFPCSESQQH---L 270 280 290 300 310 360 370 380 390 400 pF1KB7 NGLRQAPS--SYPPTWPPGPAHHSCHQ-SNSNGHRLC---PTHVYAAPEGKAPANSPRQG :: .. . :: :. : . ::. .:.: : .. :.: :: . NP_005 NGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPIDGFSQNENK---NSYLCN 320 330 340 350 360 370 410 420 430 440 450 460 pF1KB7 NSKNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQV .. . :.:::. :. .. .::::.:::::::::.:::::::.::::::::::::: NP_005 TGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQV 380 390 400 410 420 430 470 480 490 500 510 520 pF1KB7 TLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNS .::::::::::::::::::..:..:: ::: ::...: .:: ::::..::.::::::. NP_005 NLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNA 440 450 460 470 480 490 530 540 550 560 570 580 pF1KB7 LALTEEELGLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLL : :..::..::::::::::::::.:: ::: :::::.::::.:..::.: :.: ::::: NP_005 LQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLL 500 510 520 530 540 550 590 600 610 pF1KB7 LKLPDLRTLNNMHSEKLLSFRVDAQ :::::::.:::::::.::.:.: NP_005 LKLPDLRSLNNMHSEELLAFKVHP 560 570 >>NP_001138897 (OMIM: 602304) nuclear receptor subfamily (504 aa) initn: 1710 init1: 910 opt: 1699 Z-score: 985.2 bits: 192.1 E(85289): 3.9e-48 Smith-Waterman score: 1699; 55.3% identity (75.2% similar) in 517 aa overlap (107-611:1-502) 80 90 100 110 120 130 pF1KB7 DDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSP--SKSTSNITKLNGMVLLCKV :. :. .: .:: :..::..:::::::: NP_001 MKTSKSSAPGMTKSHSGVTKFSGMVLLCKV 10 20 30 140 150 160 170 180 190 pF1KB7 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCL :::::::::::::::::::::::::::::::::.:::::::::.:.:::::::::::::: NP_001 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB7 SVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-LANNQLSSQCPLETSPTQHP-TPGPMGP ::::::::::::::::::::::: ::::::. . :.:.:.. .: .: : : NP_001 SVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQE 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB7 SPPPAPVPSPLVGFSQFPQQLTPPRSP-SPEPTVEDVISQVARAHREIFTYAHDKLGSSP . : : :. :. :: : . . :.::..:.:::.. : : ... .: NP_001 QLRPKP---------QLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSA 160 170 180 190 200 320 330 340 350 360 pF1KB7 GNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLA-AQRHNEALNGLRQAPS--SYPPT ... ... : . ... : . ... . .:.: ::: .. . :: NP_001 ESMQPQRGERIPKNMEQYNLNHDHCGNGLSSHFPCSESQQH---LNGQFKGRNIMHYPNG 210 220 230 240 250 370 380 390 400 410 420 pF1KB7 WPPGPAHHSCHQ-SNSNGHRLC---PTHVYAAPEGKAPANSPRQGNSKNVLLACPMNMYP :. : . ::. .:.: : .. :.: :: ... . :.:::. : NP_001 HAICIANGHCMNFSNAYTQRVCDRVPIDGFSQNENK---NSYLCNTGGRMHLVCPMSKSP 260 270 280 290 300 310 430 440 450 460 470 480 pF1KB7 HGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRF . .. .::::.:::::::::.:::::::.:::::::::::::.:::::::::::::: NP_001 YVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRF 320 330 340 350 360 370 490 500 510 520 530 540 pF1KB7 ASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVV ::::..:..:: ::: ::...: .:: ::::..::.::::::.: :..::..:::::: NP_001 ASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVV 380 390 400 410 420 430 550 560 570 580 590 600 pF1KB7 LVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSE ::::::::.:: ::: :::::.::::.:..::.: :.: ::::::::::::.::::::: NP_001 LVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSE 440 450 460 470 480 490 610 pF1KB7 KLLSFRVDAQ .::.:.: NP_001 ELLAFKVHP 500 >>XP_006713514 (OMIM: 602304) PREDICTED: nuclear recepto (448 aa) initn: 1250 init1: 719 opt: 1134 Z-score: 664.5 bits: 132.6 E(85289): 2.8e-30 Smith-Waterman score: 1197; 45.9% identity (67.4% similar) in 482 aa overlap (9-479:4-445) 10 20 30 40 50 60 pF1KB7 MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL :.::::.::.::.:. .:: : .:..:..:::: ... :. : : ... XP_006 MEVNAGGVIAYISSSSSA---SSPASCHSEGSENSFQSSSSSVPSS-PNSSNSDT 10 20 30 40 50 70 80 90 100 110 pF1KB7 TQDPARS-FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKST . .: . ...: :..: : ..:.::. :: .:: XP_006 NGNPKNGDLANIEGILKNDRIDCSMKTSKSSA--------PGM-------------TKSH 60 70 80 90 120 130 140 150 160 170 pF1KB7 SNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVR :..::..:::::::::::::::::::::::::::::::::::::::::.:::::::::.: XP_006 SGVTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMR 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 INRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-LANNQLSSQCPLE .::::::::::::::::::::::::::::::::::::: ::::::. . :.:.:.. . XP_006 MNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQND 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB7 TSPTQHP-TPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSP-SPEPTVEDVISQVARAH : .: : : . : : :. :. :: : . . :.::..:.::: XP_006 TLVEHHEQTALPAQEQLRPKP---------QLEQENIKSSSPPSSDFAKEEVIGMVTRAH 220 230 240 250 260 300 310 320 330 340 350 pF1KB7 REIFTYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLA-AQRHNEAL .. : : ... .: ... ... : . ... : . ... . .:.: : XP_006 KDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDHCGNGLSSHFPCSESQQH---L 270 280 290 300 310 360 370 380 390 400 pF1KB7 NGLRQAPS--SYPPTWPPGPAHHSCHQ-SNSNGHRLC---PTHVYAAPEGKAPANSPRQG :: .. . :: :. : . ::. .:.: : .. :.: :: . XP_006 NGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPIDGFSQNENK---NSYLCN 320 330 340 350 360 370 410 420 430 440 450 460 pF1KB7 NSKNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQV .. . :.:::. :. .. .::::.:::::::::.:::::::.::::::::::::: XP_006 TGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQV 380 390 400 410 420 430 470 480 490 500 510 520 pF1KB7 TLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNS .::::::::. XP_006 NLLKAGTFEIDLE 440 >>XP_011532146 (OMIM: 125853,601487,601665,604367,609338 (250 aa) initn: 465 init1: 241 opt: 468 Z-score: 289.3 bits: 62.3 E(85289): 2.2e-09 Smith-Waterman score: 468; 50.8% identity (75.0% similar) in 132 aa overlap (98-228:84-205) 70 80 90 100 110 120 pF1KB7 FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPG-SLQVAMEDSSRVSPSKSTSNITKLN ::: : .. . .. . ::.: XP_011 PFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSL------- 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 GMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQ :.. :.:::: ::::::::::::::::::::.:. .. : :: . :: : . .::.:: XP_011 -MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 QCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPT :::.:::.::::..:.::::.:. ::...:::..: .. : XP_011 YCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYI 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 PGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDK XP_011 KSFPLTKAKARAILTGKTTDKSTAQVC 230 240 250 >>NP_001317544 (OMIM: 125853,601487,601665,604367,609338 (250 aa) initn: 465 init1: 241 opt: 468 Z-score: 289.3 bits: 62.3 E(85289): 2.2e-09 Smith-Waterman score: 468; 50.8% identity (75.0% similar) in 132 aa overlap (98-228:84-205) 70 80 90 100 110 120 pF1KB7 FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPG-SLQVAMEDSSRVSPSKSTSNITKLN ::: : .. . .. . ::.: NP_001 PFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSL------- 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 GMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQ :.. :.:::: ::::::::::::::::::::.:. .. : :: . :: : . .::.:: NP_001 -MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 QCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPT :::.:::.::::..:.::::.:. ::...:::..: .. : NP_001 YCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYI 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 PGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDK NP_001 KSFPLTKAKARAILTGKTTDKSTAQVC 230 240 250 >>XP_011532145 (OMIM: 125853,601487,601665,604367,609338 (278 aa) initn: 465 init1: 241 opt: 468 Z-score: 288.6 bits: 62.4 E(85289): 2.4e-09 Smith-Waterman score: 468; 50.8% identity (75.0% similar) in 132 aa overlap (98-228:112-233) 70 80 90 100 110 120 pF1KB7 FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPG-SLQVAMEDSSRVSPSKSTSNITKLN ::: : .. . .. . ::.: XP_011 PFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSL------- 90 100 110 120 130 130 140 150 160 170 180 pF1KB7 GMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQ :.. :.:::: ::::::::::::::::::::.:. .. : :: . :: : . .::.:: XP_011 -MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQ 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB7 QCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPT :::.:::.::::..:.::::.:. ::...:::..: .. : XP_011 YCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYI 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB7 PGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDK XP_011 KSFPLTKAKARAILTGKTTDKSTAQVC 260 270 >>XP_011532144 (OMIM: 125853,601487,601665,604367,609338 (445 aa) initn: 605 init1: 241 opt: 468 Z-score: 285.7 bits: 62.5 E(85289): 3.6e-09 Smith-Waterman score: 468; 50.8% identity (75.0% similar) in 132 aa overlap (98-228:112-233) 70 80 90 100 110 120 pF1KB7 FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPG-SLQVAMEDSSRVSPSKSTSNITKLN ::: : .. . .. . ::.: XP_011 PFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSL------- 90 100 110 120 130 130 140 150 160 170 180 pF1KB7 GMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQ :.. :.:::: ::::::::::::::::::::.:. .. : :: . :: : . .::.:: XP_011 -MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQ 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB7 QCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPT :::.:::.::::..:.::::.:. ::...:::..: .. : XP_011 YCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYI 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB7 PGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDK XP_011 KSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQ 260 270 280 290 300 310 >>XP_011532143 (OMIM: 125853,601487,601665,604367,609338 (477 aa) initn: 806 init1: 241 opt: 468 Z-score: 285.2 bits: 62.5 E(85289): 3.8e-09 Smith-Waterman score: 591; 29.7% identity (52.7% similar) in 512 aa overlap (98-606:84-453) 70 80 90 100 110 120 pF1KB7 FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPG-SLQVAMEDSSRVSPSKSTSNITKLN ::: : .. . .. . ::.: XP_011 PFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSL------- 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 GMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQ :.. :.:::: ::::::::::::::::::::.:. .. : :: . :: : . .::.:: XP_011 -MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 QCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPT :::.:::.::::..:.::::.:. ::...:::..: .. ::. . . ..: XP_011 YCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDID----QLNPESADLRALAKHLY 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 PGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDK . . ..:: :: .. : :.: XP_011 DSYI----------------KSFP--LTKAKA------------------RAILT----- 220 230 310 320 330 340 350 360 pF1KB7 LGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQAPSSYP :. .: . : :.: . XP_011 --------------GKTTDKSPF---------VIYDMNSLMMGED--------------- 240 250 260 370 380 390 400 410 420 pF1KB7 PTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPMNMYPHG .. :. .: : .::.: . .. .: XP_011 --------------------KIKFKHI-----------TPLQEQSKEV----AIRIF-QG 270 280 430 440 450 460 470 480 pF1KB7 RSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFAS . :.:. ::.:..:.:: :::: .:. .::::::: :. :.... .:: XP_011 CQFRSVE------------AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS 290 300 310 320 330 490 500 510 520 530 540 pF1KB7 LFNVKDQTVMFLSRTTYSLQELGAM--GMGDLLSAMFDFSEKLNSLALTEEELGLFTAVV :.: :: ... .. .. . : .. .::.. :.:. :.:.: : . .:..: ::. XP_011 LMN-KDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVI 340 350 360 370 380 390 550 560 570 580 590 600 pF1KB7 LVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSE ..:.:: :. : .:..:..::.::. . :.: .. :.::: :. ::: . . : . XP_011 ILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQ 400 410 420 430 440 450 610 pF1KB7 KLLSFRVDAQ : XP_011 LLQVIKKTETDMSLHPLLQEIYKDLY 460 470 >>NP_005028 (OMIM: 125853,601487,601665,604367,609338) p (477 aa) initn: 806 init1: 241 opt: 468 Z-score: 285.2 bits: 62.5 E(85289): 3.8e-09 Smith-Waterman score: 591; 29.7% identity (52.7% similar) in 512 aa overlap (98-606:84-453) 70 80 90 100 110 120 pF1KB7 FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPG-SLQVAMEDSSRVSPSKSTSNITKLN ::: : .. . .. . ::.: NP_005 PFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSL------- 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 GMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQ :.. :.:::: ::::::::::::::::::::.:. .. : :: . :: : . .::.:: NP_005 -MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 QCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPT :::.:::.::::..:.::::.:. ::...:::..: .. ::. . . ..: NP_005 YCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDID----QLNPESADLRALAKHLY 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 PGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDK . . ..:: :: .. : :.: NP_005 DSYI----------------KSFP--LTKAKA------------------RAILT----- 220 230 310 320 330 340 350 360 pF1KB7 LGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQAPSSYP :. .: . : :.: . NP_005 --------------GKTTDKSPF---------VIYDMNSLMMGED--------------- 240 250 260 370 380 390 400 410 420 pF1KB7 PTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPMNMYPHG .. :. .: : .::.: . .. .: NP_005 --------------------KIKFKHI-----------TPLQEQSKEV----AIRIF-QG 270 280 430 440 450 460 470 480 pF1KB7 RSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFAS . :.:. ::.:..:.:: :::: .:. .::::::: :. :.... .:: NP_005 CQFRSVE------------AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS 290 300 310 320 330 490 500 510 520 530 540 pF1KB7 LFNVKDQTVMFLSRTTYSLQELGAM--GMGDLLSAMFDFSEKLNSLALTEEELGLFTAVV :.: :: ... .. .. . : .. .::.. :.:. :.:.: : . .:..: ::. NP_005 LMN-KDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVI 340 350 360 370 380 390 550 560 570 580 590 600 pF1KB7 LVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSE ..:.:: :. : .:..:..::.::. . :.: .. :.::: :. ::: . . : . NP_005 ILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQ 400 410 420 430 440 450 610 pF1KB7 KLLSFRVDAQ : NP_005 LLQVIKKTETDMSLHPLLQEIYKDLY 460 470 614 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:35:05 2016 done: Fri Nov 4 22:35:07 2016 Total Scan time: 12.010 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]