FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7844, 587 aa 1>>>pF1KB7844 587 - 587 aa - 587 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2846+/-0.00042; mu= 4.5277+/- 0.026 mean_var=152.2282+/-30.630, 0's: 0 Z-trim(115.6): 55 B-trim: 0 in 0/55 Lambda= 0.103951 statistics sampled from 26192 (26247) to 26192 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.308), width: 16 Scan time: 10.850 The best scores are: opt bits E(85289) NP_001278675 (OMIM: 164910) proto-oncogene c-Rel i ( 587) 4001 612.4 1.4e-174 XP_011531312 (OMIM: 164910) PREDICTED: proto-oncog ( 489) 3290 505.7 1.4e-142 NP_002899 (OMIM: 164910) proto-oncogene c-Rel isof ( 619) 2178 339.0 2.8e-92 XP_016860116 (OMIM: 164910) PREDICTED: proto-oncog ( 564) 2167 337.3 8.2e-92 NP_068810 (OMIM: 164014) transcription factor p65 ( 551) 1327 211.3 6.7e-54 NP_001230914 (OMIM: 164014) transcription factor p ( 448) 1320 210.2 1.2e-53 NP_001138610 (OMIM: 164014) transcription factor p ( 548) 1305 208.0 6.6e-53 NP_001230913 (OMIM: 164014) transcription factor p ( 482) 1300 207.2 9.9e-53 XP_005259184 (OMIM: 604758) PREDICTED: transcripti ( 576) 975 158.5 5.4e-38 NP_006500 (OMIM: 604758) transcription factor RelB ( 579) 975 158.5 5.4e-38 XP_011543508 (OMIM: 164014) PREDICTED: transcripti ( 480) 959 156.1 2.4e-37 XP_011543509 (OMIM: 164014) PREDICTED: transcripti ( 445) 741 123.4 1.6e-27 XP_005259185 (OMIM: 604758) PREDICTED: transcripti ( 507) 712 119.1 3.6e-26 XP_011538132 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 523 90.8 1.7e-17 XP_011538133 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 523 90.8 1.7e-17 NP_001248332 (OMIM: 164012,615577) nuclear factor ( 899) 523 90.8 2e-17 NP_002493 (OMIM: 164012,615577) nuclear factor NF- ( 899) 523 90.8 2e-17 NP_001275653 (OMIM: 164012,615577) nuclear factor ( 899) 523 90.8 2e-17 NP_001309863 (OMIM: 164012,615577) nuclear factor ( 900) 523 90.8 2e-17 NP_001070962 (OMIM: 164012,615577) nuclear factor ( 900) 523 90.8 2e-17 XP_016871767 (OMIM: 164012,615577) PREDICTED: nucl (1081) 523 90.9 2.4e-17 NP_001309864 (OMIM: 164012,615577) nuclear factor ( 858) 507 88.4 1e-16 NP_001306155 (OMIM: 164011,616576) nuclear factor ( 968) 362 66.7 4e-10 NP_001158884 (OMIM: 164011,616576) nuclear factor ( 968) 362 66.7 4e-10 XP_011530308 (OMIM: 164011,616576) PREDICTED: nucl ( 976) 362 66.7 4e-10 XP_011530310 (OMIM: 164011,616576) PREDICTED: nucl ( 916) 360 66.4 4.7e-10 NP_003989 (OMIM: 164011,616576) nuclear factor NF- ( 969) 360 66.4 4.9e-10 >>NP_001278675 (OMIM: 164910) proto-oncogene c-Rel isofo (587 aa) initn: 4001 init1: 4001 opt: 4001 Z-score: 3255.5 bits: 612.4 E(85289): 1.4e-174 Smith-Waterman score: 4001; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587) 10 20 30 40 50 60 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 AIVFKTPPYCKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIVFKTPPYCKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 QKLCQDHVNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPTGVSSQAESYYPSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKLCQDHVNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPTGVSSQAESYYPSPG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 PISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 NDLNASNACIYNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDLNASNACIYNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 RLLSMNLENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVSQSDAFEGSDFSCADN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLLSMNLENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVSQSDAFEGSDFSCADN 490 500 510 520 530 540 550 560 570 580 pF1KB7 SMINESGPSNSTNPNSHGFVQDSQYSGIGSMQNEQLSDSFPYEFFQV ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMINESGPSNSTNPNSHGFVQDSQYSGIGSMQNEQLSDSFPYEFFQV 550 560 570 580 >>XP_011531312 (OMIM: 164910) PREDICTED: proto-oncogene (489 aa) initn: 3290 init1: 3290 opt: 3290 Z-score: 2680.5 bits: 505.7 E(85289): 1.4e-142 Smith-Waterman score: 3290; 99.8% identity (99.8% similar) in 488 aa overlap (100-587:2-489) 70 80 90 100 110 120 pF1KB7 DPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAIITRIKAGINP : :::::::::::::::::::::::::::: XP_011 MLCFQNLGIRCVKKKEVKEAIITRIKAGINP 10 20 30 130 140 150 160 170 180 pF1KB7 FNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRAPNTAELRIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRAPNTAELRIC 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB7 RVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQVAIVFKTPPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQVAIVFKTPPY 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB7 CKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLFQKLCQDHVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLFQKLCQDHVN 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB7 FPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPTGVSSQAESYYPSPGPISSGLSHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPTGVSSQAESYYPSPGPISSGLSHH 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB7 ASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVGNDLNASNAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVGNDLNASNAC 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB7 IYNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNPRLLSMNLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNPRLLSMNLEN 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB7 PSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVSQSDAFEGSDFSCADNSMINESGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVSQSDAFEGSDFSCADNSMINESGPS 400 410 420 430 440 450 550 560 570 580 pF1KB7 NSTNPNSHGFVQDSQYSGIGSMQNEQLSDSFPYEFFQV :::::::::::::::::::::::::::::::::::::: XP_011 NSTNPNSHGFVQDSQYSGIGSMQNEQLSDSFPYEFFQV 460 470 480 >>NP_002899 (OMIM: 164910) proto-oncogene c-Rel isoform (619 aa) initn: 2120 init1: 2120 opt: 2178 Z-score: 1777.6 bits: 339.0 E(85289): 2.8e-92 Smith-Waterman score: 3927; 94.8% identity (94.8% similar) in 619 aa overlap (1-587:1-619) 10 20 30 40 50 60 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 AIVFKTPPYCKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AIVFKTPPYCKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLF 250 260 270 280 290 300 310 320 pF1KB7 QKLCQDHV--------------------------------NFPERPRPGLLGSIGEGRYF :::::::: :::::::::::::::::::: NP_002 QKLCQDHVETGFRHVDQDGLELLTSGDPPTLASQSAGITVNFPERPRPGLLGSIGEGRYF 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB7 KKEPNLFSHDAVVREMPTGVSSQAESYYPSPGPISSGLSHHASMAPLPSSSWSSVAHPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KKEPNLFSHDAVVREMPTGVSSQAESYYPSPGPISSGLSHHASMAPLPSSSWSSVAHPTP 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 RSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVGNDLNASNACIYNNADDIVGMEASSMPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVGNDLNASNACIYNNADDIVGMEASSMPSA 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB7 DLYGISDPNMLSNCSVNMMTTSSDSMGETDNPRLLSMNLENPSCNSVLDPRDLRQLHQMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DLYGISDPNMLSNCSVNMMTTSSDSMGETDNPRLLSMNLENPSCNSVLDPRDLRQLHQMS 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB7 SSSMSAGANSNTTVFVSQSDAFEGSDFSCADNSMINESGPSNSTNPNSHGFVQDSQYSGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SSSMSAGANSNTTVFVSQSDAFEGSDFSCADNSMINESGPSNSTNPNSHGFVQDSQYSGI 550 560 570 580 590 600 570 580 pF1KB7 GSMQNEQLSDSFPYEFFQV ::::::::::::::::::: NP_002 GSMQNEQLSDSFPYEFFQV 610 >>XP_016860116 (OMIM: 164910) PREDICTED: proto-oncogene (564 aa) initn: 3824 init1: 2115 opt: 2167 Z-score: 1769.3 bits: 337.3 E(85289): 8.2e-92 Smith-Waterman score: 3782; 96.1% identity (96.1% similar) in 587 aa overlap (1-587:1-564) 10 20 30 40 50 60 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 AIVFKTPPYCKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIVFKTPPYCKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 QKLCQDHVNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPTGVSSQAESYYPSPG ::::::: :::::::::::::::::::::::::::::: XP_016 QKLCQDH-----------------------EPNLFSHDAVVREMPTGVSSQAESYYPSPG 310 320 330 370 380 390 400 410 420 pF1KB7 PISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB7 NDLNASNACIYNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDLNASNACIYNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNP 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB7 RLLSMNLENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVSQSDAFEGSDFSCADN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLSMNLENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVSQSDAFEGSDFSCADN 460 470 480 490 500 510 550 560 570 580 pF1KB7 SMINESGPSNSTNPNSHGFVQDSQYSGIGSMQNEQLSDSFPYEFFQV ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMINESGPSNSTNPNSHGFVQDSQYSGIGSMQNEQLSDSFPYEFFQV 520 530 540 550 560 >>NP_068810 (OMIM: 164014) transcription factor p65 isof (551 aa) initn: 1095 init1: 613 opt: 1327 Z-score: 1088.7 bits: 211.3 E(85289): 6.7e-54 Smith-Waterman score: 1327; 46.9% identity (70.7% similar) in 461 aa overlap (5-461:16-465) 10 20 30 40 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS : .::.::::::.:::::::::::::::::::::.:::...:.:. NP_068 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC :.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.: NP_068 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP :::.....:: ::... :::.:: :.: .: :::.::::::: . : : :: NP_068 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK ::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::. NP_068 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY : ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : . NP_068 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 GNKAKKQKTTLLFQKLCQDH-VNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPT . :...: :... . . : ::: .: . :. . . . NP_068 RIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQP---YPFTS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 GVSSQAESYYPSPGPISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPS ..:. . .:. :. .:. ...:: : . .. :.: . .. :.. . .: NP_068 SLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQ-APAPVPV 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB7 NSQGIPPFLRIPVGNDLNASNACIYNNADDIVGMEASSMPSADLYGIS-DPNMLSNCSVN . : : . :. . .:... . .. .. .. .. . : : : :: .... NP_068 LAPGPPQAVAPPAPKPTQAGEGTL---SEALLQLQFDDEDLGALLGNSTDPAVFTDLASV 420 430 440 450 460 470 480 490 500 510 520 pF1KB7 MMTTSSDSMGETDNPRLLSMNLENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVS NP_068 DNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLS 470 480 490 500 510 520 >>NP_001230914 (OMIM: 164014) transcription factor p65 i (448 aa) initn: 1095 init1: 613 opt: 1320 Z-score: 1084.4 bits: 210.2 E(85289): 1.2e-53 Smith-Waterman score: 1320; 50.6% identity (72.4% similar) in 413 aa overlap (5-412:16-421) 10 20 30 40 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS : .::.::::::.:::::::::::::::::::::.:::...:.:. NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC :.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.: NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP :::.....:: ::... :::.:: :.: .: :::.::::::: . : : :: NP_001 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK ::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::. NP_001 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY : ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : . NP_001 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 GNKAKKQKTTLLFQKLCQDH-VNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPT . :...: :... . . : ::: .: . :. . . . NP_001 RIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQP---YPFTS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 GVSSQAESYYPSPGPISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPS ..:. . .:. :. .:. ...:: : . .. :.: . .. :.. :. NP_001 SLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQRPPDPAPA 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB7 --NSQGIPPFLRIPVGNDLNASNACIYNNADDIVGMEASSMPSADLYGISDPNMLSNCSV .. :.: NP_001 PLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS 420 430 440 >>NP_001138610 (OMIM: 164014) transcription factor p65 i (548 aa) initn: 1083 init1: 601 opt: 1305 Z-score: 1070.9 bits: 208.0 E(85289): 6.6e-53 Smith-Waterman score: 1310; 46.5% identity (70.4% similar) in 460 aa overlap (5-461:16-462) 10 20 30 40 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS : .::.::::::.:::::::::::::::::::::.:::...:.:. NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC :.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.: NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 VKKKEVKEAIITRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPP :::.....:: ::... :::. :.: .: :::.::::::: . : : ::: NP_001 VKKRDLEQAISQRIQTNNNPFQ--EEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLPP 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 VVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKG :.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::.: NP_001 VLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 IFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYG ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : . NP_001 SFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHR 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 NKAKKQKTTLLFQKLCQDH-VNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPTG . :...: :... . . : ::: .: . :. . . .. NP_001 IEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQP---YPFTSS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 VSSQAESYYPSPGPISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSN .:. . .:. :. .:. ...:: : . .. :.: . .. :.. . .: NP_001 LSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQ-APAPVPVL 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB7 SQGIPPFLRIPVGNDLNASNACIYNNADDIVGMEASSMPSADLYGIS-DPNMLSNCSVNM . : : . :. . .:... . .. .. .. .. . : : : :: .... NP_001 APGPPQAVAPPAPKPTQAGEGTL---SEALLQLQFDDEDLGALLGNSTDPAVFTDLASVD 420 430 440 450 460 470 480 490 500 510 520 pF1KB7 MTTSSDSMGETDNPRLLSMNLENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVSQ NP_001 NSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSG 470 480 490 500 510 520 >>NP_001230913 (OMIM: 164014) transcription factor p65 i (482 aa) initn: 1230 init1: 613 opt: 1300 Z-score: 1067.7 bits: 207.2 E(85289): 9.9e-53 Smith-Waterman score: 1300; 61.6% identity (80.3% similar) in 315 aa overlap (5-316:16-326) 10 20 30 40 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS : .::.::::::.:::::::::::::::::::::.:::...:.:. NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC :.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.: NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP :::.....:: ::... :::.:: :.: .: :::.::::::: . : : :: NP_001 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK ::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::. NP_001 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY : ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : . NP_001 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 GNKAKKQKTTLLFQKLCQDH-VNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPT . :...: :... . . : ::: NP_001 RIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPGPPQAVAPPA 300 310 320 330 340 350 >>XP_005259184 (OMIM: 604758) PREDICTED: transcription f (576 aa) initn: 557 init1: 457 opt: 975 Z-score: 803.1 bits: 158.5 E(85289): 5.4e-38 Smith-Waterman score: 975; 50.3% identity (76.4% similar) in 292 aa overlap (8-295:122-410) 10 20 30 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPG :.. : :::.::::::::.::::::::: : XP_005 LGPVAPPATPPPWGCPLGRLVSPAPGPGPQPHLVITEQPKQRGMRFRYECEGRSAGSILG 100 110 120 130 140 150 40 50 60 70 80 90 pF1KB7 EHSTDNNRTYPSIQIMNYYGKGKVRIT--LVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQ : ::. ..: :.:.. . : .:..: :: :. :.. :::.:::::: :: .... XP_005 ESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGICRVRLRP 160 170 180 190 200 210 100 110 120 130 140 150 pF1KB7 ERRPLF-FQNLGIRCVKKKEVKEAIITRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQV . : :.::::.::.:::.. :: .:. ::.:.:. .:.. .. :.::::.:::. XP_005 HVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAG--SLKNHQEVDMNVVRICFQA 220 230 240 250 260 160 170 180 190 200 210 pF1KB7 FLPDEHGNLTTALPPVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKD :..:.. . ::.:.:.::... ::.::::::.::. : ::.:..::::::::. XP_005 SYRDQQGQMRR-MDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKE 270 280 290 300 310 320 220 230 240 250 260 270 pF1KB7 DIEVRFVLNDWEAKGIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSE :: : : .::... :::::::::.::::::::: :.:::::.. :.: .: :: XP_005 DISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSE 330 340 350 360 370 380 280 290 300 310 320 330 pF1KB7 SMDFRYLPDEKDTYGNKAKKQKTTLLFQKLCQDHVNFPERPRPGLLGSIGEGRYFKKEPN . : ::: ..:.:: :... XP_005 PLPFTYLPRDHDSYGVDKKRKRGMPDVLGELNSSDPHGIESKRRKKKPAILDHFLPNHGS 390 400 410 420 430 440 >>NP_006500 (OMIM: 604758) transcription factor RelB [Ho (579 aa) initn: 557 init1: 457 opt: 975 Z-score: 803.0 bits: 158.5 E(85289): 5.4e-38 Smith-Waterman score: 975; 50.3% identity (76.4% similar) in 292 aa overlap (8-295:125-413) 10 20 30 pF1KB7 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPG :.. : :::.::::::::.::::::::: : NP_006 LGPVAPPATPPPWGCPLGRLVSPAPGPGPQPHLVITEQPKQRGMRFRYECEGRSAGSILG 100 110 120 130 140 150 40 50 60 70 80 90 pF1KB7 EHSTDNNRTYPSIQIMNYYGKGKVRIT--LVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQ : ::. ..: :.:.. . : .:..: :: :. :.. :::.:::::: :: .... NP_006 ESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGICRVRLRP 160 170 180 190 200 210 100 110 120 130 140 150 pF1KB7 ERRPLF-FQNLGIRCVKKKEVKEAIITRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQV . : :.::::.::.:::.. :: .:. ::.:.:. .:.. .. :.::::.:::. NP_006 HVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAG--SLKNHQEVDMNVVRICFQA 220 230 240 250 260 270 160 170 180 190 200 210 pF1KB7 FLPDEHGNLTTALPPVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKD :..:.. . ::.:.:.::... ::.::::::.::. : ::.:..::::::::. NP_006 SYRDQQGQMRR-MDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKE 280 290 300 310 320 330 220 230 240 250 260 270 pF1KB7 DIEVRFVLNDWEAKGIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSE :: : : .::... :::::::::.::::::::: :.:::::.. :.: .: :: NP_006 DISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSE 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB7 SMDFRYLPDEKDTYGNKAKKQKTTLLFQKLCQDHVNFPERPRPGLLGSIGEGRYFKKEPN . : ::: ..:.:: :... NP_006 PLPFTYLPRDHDSYGVDKKRKRGMPDVLGELNSSDPHGIESKRRKKKPAILDHFLPNHGS 400 410 420 430 440 450 587 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:36:23 2016 done: Fri Nov 4 22:36:25 2016 Total Scan time: 10.850 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]