FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7851, 548 aa 1>>>pF1KB7851 548 - 548 aa - 548 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.3532+/-0.000895; mu= -6.1561+/- 0.054 mean_var=386.1243+/-78.725, 0's: 0 Z-trim(118.3): 91 B-trim: 204 in 1/53 Lambda= 0.065270 statistics sampled from 19126 (19218) to 19126 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.834), E-opt: 0.2 (0.59), width: 16 Scan time: 4.180 The best scores are: opt bits E(32554) CCDS12600.1 ERF gene_id:2077|Hs108|chr19 ( 548) 3864 377.5 2.3e-104 CCDS77308.1 ERF gene_id:2077|Hs108|chr19 ( 473) 3320 326.2 5.4e-89 CCDS44250.1 ETV3 gene_id:2117|Hs108|chr1 ( 512) 962 104.2 4e-22 CCDS1164.1 ETV3 gene_id:2117|Hs108|chr1 ( 143) 718 80.7 1.3e-15 CCDS30893.1 ETV3L gene_id:440695|Hs108|chr1 ( 361) 704 79.8 6.3e-15 >>CCDS12600.1 ERF gene_id:2077|Hs108|chr19 (548 aa) initn: 3864 init1: 3864 opt: 3864 Z-score: 1987.2 bits: 377.5 E(32554): 2.3e-104 Smith-Waterman score: 3864; 100.0% identity (100.0% similar) in 548 aa overlap (1-548:1-548) 10 20 30 40 50 60 pF1KB7 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARLPHDPGVFRVYPRPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARLPHDPGVFRVYPRPRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 SHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 PSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGLAEGAGALAPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGLAEGAGALAPPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 PPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGASQCMPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGASQCMPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 KLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 KLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQ 490 500 510 520 530 540 pF1KB7 LSLEHRDS :::::::: CCDS12 LSLEHRDS >>CCDS77308.1 ERF gene_id:2077|Hs108|chr19 (473 aa) initn: 3320 init1: 3320 opt: 3320 Z-score: 1711.2 bits: 326.2 E(32554): 5.4e-89 Smith-Waterman score: 3320; 100.0% identity (100.0% similar) in 473 aa overlap (76-548:1-473) 50 60 70 80 90 100 pF1KB7 IAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYK :::::::::::::::::::::::::::::: CCDS77 MNYDKLSRALRYYYNKRILHKTKGKRFTYK 10 20 30 110 120 130 140 150 160 pF1KB7 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FNFNKLVLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPAC 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB7 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB7 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSP 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB7 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRP 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB7 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGS 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB7 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPK 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB7 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PEPGEAPGASQCMPLKLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPL 400 410 420 430 440 450 530 540 pF1KB7 TPRRVSSDLQHATAQLSLEHRDS ::::::::::::::::::::::: CCDS77 TPRRVSSDLQHATAQLSLEHRDS 460 470 >>CCDS44250.1 ETV3 gene_id:2117|Hs108|chr1 (512 aa) initn: 1060 init1: 480 opt: 962 Z-score: 510.8 bits: 104.2 E(32554): 4e-22 Smith-Waterman score: 1324; 45.6% identity (63.0% similar) in 551 aa overlap (2-502:10-504) 10 20 30 40 50 pF1KB7 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQ-GD : . :. ::::::: :::::::::::::::::::.:::.. ::::: :. CCDS44 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 YGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: CCDS44 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 VLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSS :. :::::.. ..:.:::::::::...:.:.::: .. :::.: . : :.:: CCDS44 VMPNYPFINIR-SSGVVPQSAPPVPTASSRFHFPP---LDTHSPTNDVQ-PGRFSASS-- 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGP-PDLGAFRGPPLARLPHDPG ..: .. .: . ::::. . : : : : . .:. : ... . : CCDS44 ----LTASGQESSNGTDRKTELSELEDGSAADWR-RGVDPVSSRNAIGGGGIGHQKRKPD 180 190 200 210 220 240 250 260 270 280 pF1KB7 V-FRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPS . . .. :: :.: ::: :::. : :..: .:::: .::: ..:.::: :::. : CCDS44 IMLPLFARPGMYPDPHSPFAVSPIPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSS 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 GGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCP : :::.::.::.::.... ::.:::::::.: .::::.:: : .: CCDS44 -----------SCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVP----PLQC- 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 LPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGL : :: :. :..::::::.::..: :.. .: . . ... CCDS44 --QMHPEE--------------STQFSIKLQPPPVGRKNRERVESSEESAPVTTPTMASI 340 350 360 370 410 420 430 440 450 pF1KB7 AEGAGALAPPPPPPQIKVEPISEGESEEV-----EVTDISDED---------EEDGEVFK ::.::::: :: . : . : . ..:. :: : .: CCDS44 ------------PPRIKVEPASEKDPESLRQSAREKEEHTQEEGTVPSRTIEEEKGTIFA 380 390 400 410 420 460 470 480 490 pF1KB7 TPRAPPAPP---------KP---------EPGEAPGASQ-----CMPLKLRFKRRWSEDC : ::: : .: .::. :.: . :: :::.::::..: CCDS44 RPAAPPIWPSVPISTPSGEPLEVTEDSEDRPGKEPSAPEKKEDALMPPKLRLKRRWNDDP 430 440 450 460 470 480 500 510 520 530 540 pF1KB7 R----------LEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQLS . : .:.:: : CCDS44 EARELSKSGKFLWNGSGPQGLATAAADA 490 500 510 >>CCDS1164.1 ETV3 gene_id:2117|Hs108|chr1 (143 aa) initn: 719 init1: 475 opt: 718 Z-score: 394.0 bits: 80.7 E(32554): 1.3e-15 Smith-Waterman score: 718; 82.4% identity (90.4% similar) in 125 aa overlap (2-125:10-134) 10 20 30 40 50 pF1KB7 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQ-GD : . :. ::::::: :::::::::::::::::::.:::.. ::::: :. CCDS11 MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 YGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: CCDS11 YGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 VLVNYPFIDVGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSS :. :::::.. .: CCDS11 VMPNYPFINIRSSGKIQTLLVGN 130 140 >>CCDS30893.1 ETV3L gene_id:440695|Hs108|chr1 (361 aa) initn: 548 init1: 460 opt: 704 Z-score: 381.5 bits: 79.8 E(32554): 6.3e-15 Smith-Waterman score: 835; 51.4% identity (63.0% similar) in 319 aa overlap (7-294:19-326) 10 20 30 40 pF1KB7 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAW .:.:::::::: :::::::::::::::::::.:::.. :::: CCDS30 MHCSCLAEGIPANPGNWISGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAW 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 Q-GDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFN : :.::::::::::::::::: :::::::::::::::::::::::::::::::::::::: CCDS30 QQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFN 70 80 90 100 110 120 110 120 130 140 150 pF1KB7 FNKLVLVNYPFIDV------GLAGGAVPQSAPP-VPSGGS----H-FRFPPSTPSEVLSP :.::..::::. .: : :: : :: : . : . : .. : :. CCDS30 FSKLIVVNYPLWEVRAPPSPHLLLGAPALCRPALVPVGVQSELLHSMLFAHQAMVEQLTG 130 140 150 160 170 180 160 170 180 190 200 pF1KB7 TEDPRSPPACSS----SSSSLF---SAVVARRLGR----GSVSDCSDGTSELEEPLGEDP . ::.:: :. ::::.. :: ::: :::. :.. . :: : CCDS30 QQTPRGPPETSGDKKGSSSSVYRLGSAPGPCRLGLCCHLGSVQGELPGVASFTPPL---P 190 200 210 220 230 210 220 230 240 250 pF1KB7 RARPPGPPDLGAFRGPPLARLPHD---PGVFR---VYPRPRGGPEPLSPFPVSPL-AGPG :: : . . :: : :: . ::.:. . : ::. : :: :: :: : CCDS30 ---PPLPSNWTCLSGPFLPPLPSEQQLPGAFKPDILLPGPRSLPGAWH-FPGLPLLAGLG 240 250 260 270 280 290 260 270 280 290 300 310 pF1KB7 SLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAH . .: : . : : :.: : .:: : CCDS30 QGAGERLW-LLSLRPEGLEVKPAPM---MEAKGGLDPREVFCPETRRLKTGEESLTSPNL 300 310 320 330 340 320 330 340 350 360 370 pF1KB7 TQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKF CCDS30 ENLKAVWPLDPP 350 360 548 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:38:24 2016 done: Fri Nov 4 22:38:24 2016 Total Scan time: 4.180 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]