FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7855, 551 aa
1>>>pF1KB7855 551 - 551 aa - 551 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.3855+/-0.000461; mu= -19.1978+/- 0.029
mean_var=463.4397+/-96.791, 0's: 0 Z-trim(122.9): 38 B-trim: 1815 in 1/57
Lambda= 0.059577
statistics sampled from 41810 (41848) to 41810 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.491), width: 16
Scan time: 10.830
The best scores are: opt bits E(85289)
NP_068810 (OMIM: 164014) transcription factor p65 ( 551) 3783 339.6 1.5e-92
NP_001138610 (OMIM: 164014) transcription factor p ( 548) 3747 336.5 1.3e-91
NP_001230914 (OMIM: 164014) transcription factor p ( 448) 2853 259.6 1.5e-68
NP_001230913 (OMIM: 164014) transcription factor p ( 482) 2435 223.7 1e-57
XP_011543509 (OMIM: 164014) PREDICTED: transcripti ( 445) 1770 166.5 1.5e-40
XP_011543508 (OMIM: 164014) PREDICTED: transcripti ( 480) 1742 164.1 8.7e-40
NP_001278675 (OMIM: 164910) proto-oncogene c-Rel i ( 587) 1327 128.5 5.6e-29
XP_016860116 (OMIM: 164910) PREDICTED: proto-oncog ( 564) 1325 128.4 6.1e-29
NP_002899 (OMIM: 164910) proto-oncogene c-Rel isof ( 619) 1311 127.2 1.5e-28
XP_005259184 (OMIM: 604758) PREDICTED: transcripti ( 576) 1142 112.6 3.4e-24
NP_006500 (OMIM: 604758) transcription factor RelB ( 579) 1142 112.6 3.4e-24
XP_011531312 (OMIM: 164910) PREDICTED: proto-oncog ( 489) 851 87.6 1e-16
XP_005259185 (OMIM: 604758) PREDICTED: transcripti ( 507) 779 81.4 7.5e-15
XP_011538132 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 505 58.0 1.3e-07
XP_011538133 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 505 58.0 1.3e-07
NP_001309864 (OMIM: 164012,615577) nuclear factor ( 858) 397 48.7 8.7e-05
NP_001248332 (OMIM: 164012,615577) nuclear factor ( 899) 397 48.7 9.1e-05
NP_001275653 (OMIM: 164012,615577) nuclear factor ( 899) 397 48.7 9.1e-05
NP_002493 (OMIM: 164012,615577) nuclear factor NF- ( 899) 397 48.7 9.1e-05
NP_001309863 (OMIM: 164012,615577) nuclear factor ( 900) 397 48.7 9.1e-05
NP_001070962 (OMIM: 164012,615577) nuclear factor ( 900) 397 48.7 9.1e-05
XP_016871767 (OMIM: 164012,615577) PREDICTED: nucl (1081) 397 48.8 0.00011
XP_011530310 (OMIM: 164011,616576) PREDICTED: nucl ( 916) 358 45.4 0.00094
NP_003989 (OMIM: 164011,616576) nuclear factor NF- ( 969) 358 45.4 0.00098
NP_001158884 (OMIM: 164011,616576) nuclear factor ( 968) 357 45.3 0.001
NP_001306155 (OMIM: 164011,616576) nuclear factor ( 968) 357 45.3 0.001
XP_011530308 (OMIM: 164011,616576) PREDICTED: nucl ( 976) 357 45.3 0.0011
>>NP_068810 (OMIM: 164014) transcription factor p65 isof (551 aa)
initn: 3783 init1: 3783 opt: 3783 Z-score: 1782.5 bits: 339.6 E(85289): 1.5e-92
Smith-Waterman score: 3783; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
490 500 510 520 530 540
550
pF1KB7 DFSALLSQISS
:::::::::::
NP_068 DFSALLSQISS
550
>>NP_001138610 (OMIM: 164014) transcription factor p65 i (548 aa)
initn: 3749 init1: 2762 opt: 3747 Z-score: 1765.8 bits: 336.5 E(85289): 1.3e-91
Smith-Waterman score: 3747; 99.5% identity (99.5% similar) in 551 aa overlap (1-551:1-548)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
NP_001 VKKRDLEQAISQRIQTNNNPFQ---EEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
130 140 150 160 170
190 200 210 220 230 240
pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
480 490 500 510 520 530
550
pF1KB7 DFSALLSQISS
:::::::::::
NP_001 DFSALLSQISS
540
>>NP_001230914 (OMIM: 164014) transcription factor p65 i (448 aa)
initn: 2987 init1: 2817 opt: 2853 Z-score: 1351.8 bits: 259.6 E(85289): 1.5e-68
Smith-Waterman score: 2885; 81.3% identity (81.3% similar) in 551 aa overlap (1-551:1-448)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQ---------------
370 380 390 400
430 440 450 460 470 480
pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
NP_001 ------------------------------------------------------------
490 500 510 520 530 540
pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
::::::::::::::::::::::::::::::::
NP_001 ----------------------------RPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
410 420 430
550
pF1KB7 DFSALLSQISS
:::::::::::
NP_001 DFSALLSQISS
440
>>NP_001230913 (OMIM: 164014) transcription factor p65 i (482 aa)
initn: 2503 init1: 2422 opt: 2435 Z-score: 1157.2 bits: 223.7 E(85289): 1e-57
Smith-Waterman score: 3170; 87.5% identity (87.5% similar) in 551 aa overlap (1-551:1-482)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKP----------------
310 320 330 340
370 380 390 400 410 420
pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
:::::::
NP_001 -----------------------------------------------------APGPPQA
350
430 440 450 460 470 480
pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
420 430 440 450 460 470
550
pF1KB7 DFSALLSQISS
:::::::::::
NP_001 DFSALLSQISS
480
>>XP_011543509 (OMIM: 164014) PREDICTED: transcription f (445 aa)
initn: 1741 init1: 1741 opt: 1770 Z-score: 848.8 bits: 166.5 E(85289): 1.5e-40
Smith-Waterman score: 2823; 80.6% identity (80.8% similar) in 551 aa overlap (1-551:1-445)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
::::::.
XP_011 HPIFDNH-----------------------------------------------------
250 260 270 280 290 300
pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
:::::::
XP_011 -----------------------------------------------------DRHRIEE
190
310 320 330 340 350 360
pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
200 210 220 230 240 250
370 380 390 400 410 420
pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
260 270 280 290 300 310
430 440 450 460 470 480
pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
320 330 340 350 360 370
490 500 510 520 530 540
pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
380 390 400 410 420 430
550
pF1KB7 DFSALLSQISS
:::::::::::
XP_011 DFSALLSQISS
440
>>XP_011543508 (OMIM: 164014) PREDICTED: transcription f (480 aa)
initn: 1742 init1: 1742 opt: 1742 Z-score: 835.3 bits: 164.1 E(85289): 8.7e-40
Smith-Waterman score: 3142; 87.1% identity (87.1% similar) in 551 aa overlap (1-551:1-480)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
:::::::::::::::::::::::::::::::::::::::::
XP_011 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQK-------------------
190 200 210 220
250 260 270 280 290 300
pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
::::::::
XP_011 ----------------------------------------------------DDRHRIEE
310 320 330 340 350 360
pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
290 300 310 320 330 340
430 440 450 460 470 480
pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
350 360 370 380 390 400
490 500 510 520 530 540
pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
410 420 430 440 450 460
550
pF1KB7 DFSALLSQISS
:::::::::::
XP_011 DFSALLSQISS
470 480
>>NP_001278675 (OMIM: 164910) proto-oncogene c-Rel isofo (587 aa)
initn: 1095 init1: 613 opt: 1327 Z-score: 641.2 bits: 128.5 E(85289): 5.6e-29
Smith-Waterman score: 1327; 46.9% identity (70.9% similar) in 461 aa overlap (16-465:5-461)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
: .::.::::::.:::::::::::::::::::::.:::...:.:.
NP_001 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS
10 20 30 40
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
:.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.:
NP_001 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC
50 60 70 80 90 100
130 140 150 160 170
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP
:::.....:: ::... :::.:: :.: .: :::.::::::: . : : ::
NP_001 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR
::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::.
NP_001 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH
: ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : .
NP_001 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 RIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQP---YPFTS
. :...: :... . . . : ::: .: . :. . . .
NP_001 GNKAKKQKTTLLFQKLCQ-DHVNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPT
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 SLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQ-APAPVPV
..:. . .:. :. .:. ...:: : . .. :.: . .. :.. . .:
NP_001 GVSSQAESYYPSPGPISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPS
350 360 370 380 390 400
420 430 440 450 460
pF1KB7 LAPGPPQAVAPPAPKPTQAGEGTL---SEALLQLQFDDEDLGALLGNSTDPAVFTDLASV
. : : . :. . .:... . .. .. .. .. . : : : :: ....
NP_001 NSQGIPPFLRIPVGNDLNASNACIYNNADDIVGMEASSMPSADLYGIS-DPNMLSNCSVN
410 420 430 440 450 460
470 480 490 500 510 520
pF1KB7 DNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLS
NP_001 MMTTSSDSMGETDNPRLLSMNLENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVS
470 480 490 500 510 520
>>XP_016860116 (OMIM: 164910) PREDICTED: proto-oncogene (564 aa)
initn: 1231 init1: 613 opt: 1325 Z-score: 640.6 bits: 128.4 E(85289): 6.1e-29
Smith-Waterman score: 1325; 52.7% identity (74.4% similar) in 387 aa overlap (16-395:5-389)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
: .::.::::::.:::::::::::::::::::::.:::...:.:.
XP_016 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS
10 20 30 40
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
:.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.:
XP_016 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC
50 60 70 80 90 100
130 140 150 160 170
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP
:::.....:: ::... :::.:: :.: .: :::.::::::: . : : ::
XP_016 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR
::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::.
XP_016 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH
: ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : .
XP_016 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 RIEEKRKRTYETFKSIMK-KSP--FSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTS
. :...: :... . . : :: . : : .. ..: : : . .
XP_016 GNKAKKQKTTLLFQKLCQDHEPNLFSHDAVVREMPTGVSSQAESYYPSPGPISSGLSHHA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 SLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVL
:.. . . . ... :. . .... :. ..::. :
XP_016 SMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVGNDLNASNACI
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB7 APGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSE
XP_016 YNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNPRLLSMNLENP
410 420 430 440 450 460
>>NP_002899 (OMIM: 164910) proto-oncogene c-Rel isoform (619 aa)
initn: 1095 init1: 613 opt: 1311 Z-score: 633.5 bits: 127.2 E(85289): 1.5e-28
Smith-Waterman score: 1314; 50.0% identity (70.9% similar) in 426 aa overlap (16-427:5-421)
10 20 30 40 50 60
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
: .::.::::::.:::::::::::::::::::::.:::...:.:.
NP_002 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS
10 20 30 40
70 80 90 100 110 120
pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
:.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.:
NP_002 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC
50 60 70 80 90 100
130 140 150 160 170
pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP
:::.....:: ::... :::.:: :.: .: :::.::::::: . : : ::
NP_002 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR
::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::.
NP_002 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH
: ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : .
NP_002 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY
230 240 250 260 270 280
300 310 320 330 340
pF1KB7 RIEEKRKRTYETFKSIMKKSPFSG--PTDPR--------PPPRRIAVPSRSSASVPKPAP
. :...: :... . .: .: :: . . ... :. :
NP_002 GNKAKKQKTTLLFQKLCQDHVETGFRHVDQDGLELLTSGDPPTLASQSAGITVNFPE-RP
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB7 QPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQA
.: . : . . :.. .:. ... : : :: . :.:. .:. .
NP_002 RPGLLGSIGEGRYFKKEPNL------FSHDAVVREMPTGVSSQAESYYPSPGPISSGLSH
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB7 PAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDL
: . : . ..:: :.:.
NP_002 HASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVGNDLNASNA
410 420 430 440 450 460
>>XP_005259184 (OMIM: 604758) PREDICTED: transcription f (576 aa)
initn: 1080 init1: 736 opt: 1142 Z-score: 555.4 bits: 112.6 E(85289): 3.4e-24
Smith-Waterman score: 1142; 42.4% identity (68.4% similar) in 446 aa overlap (7-436:111-549)
10 20 30
pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRY
:. :: :. . :.. : ::::::::::::
XP_005 SRGAASLSTVTLGPVAPPATPPPWGCPLGRLVSPA-PGPGPQPHLVITEQPKQRGMRFRY
90 100 110 120 130
40 50 60 70 80 90
pF1KB7 KCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRIS--LVTKDPPHRPHPHELVGKD
.::::::::: :: ::...:: :.:.. : :... :: :: ::: ::: :::::
XP_005 ECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKD
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB7 CRDGFYEAELCPDRCI-HSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYD
: ::. ...: : :::.:::::::.:...: :: ..:: . .:... ... . :
XP_005 CTDGICRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVD
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB7 LNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIF
.:.::.:::.. :: .:. :. ::::.:..:... ::.::.:::.:..:: : ::.:..
XP_005 MNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELY
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB7 LLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLR
::::::::::: : :. .::.:..:::::::::.::::.:::: : . :: :.. :.
XP_005 LLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQ
320 330 340 350 360 370
280 290 300 310 320
pF1KB7 RPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPR----PPPR
: .: :::. : ::: : . ...:::: . . ...: : . : :
XP_005 RLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGMPDVLGELNSSDPHGIESKRRKKKPAIL
380 390 400 410 420 430
330 340 350 360 370 380
pF1KB7 RIAVPSRSSASVPKPA---PQPYPFTSSLSTINYDEFPTMVFPSGQ--ISQASALAPAPP
.:...:. :. :.: :....: .: . :.: .... : :. :
XP_005 DHFLPNHGSGPFLPPSALLPDPDFFSGTVS------LPGLEPPGGPDLLDDGFAYDPTAP
440 450 460 470 480 490
390 400 410 420 430 440
pF1KB7 QVLPQAPAPAPAPAMVSALAQAPAPVPVLA--PGP-PQAV-APPAPKPTQAGEGTLSEAL
.. . ::: .::.. . . :.. ::: : .. . :: : ..: ..:
XP_005 TLFTMLDLLPPAPPHASAVVCSGGAGAVVGETPGPEPLTLDSYQAPGPGDGGTASLVGSN
500 510 520 530 540 550
450 460 470 480 490 500
pF1KB7 LQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAI
XP_005 MFPNHYREAAFGGGLLSPGPEAT
560 570
551 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:09:01 2016 done: Fri Nov 4 21:09:02 2016
Total Scan time: 10.830 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]