FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7855, 551 aa 1>>>pF1KB7855 551 - 551 aa - 551 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.3855+/-0.000461; mu= -19.1978+/- 0.029 mean_var=463.4397+/-96.791, 0's: 0 Z-trim(122.9): 38 B-trim: 1815 in 1/57 Lambda= 0.059577 statistics sampled from 41810 (41848) to 41810 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.491), width: 16 Scan time: 10.830 The best scores are: opt bits E(85289) NP_068810 (OMIM: 164014) transcription factor p65 ( 551) 3783 339.6 1.5e-92 NP_001138610 (OMIM: 164014) transcription factor p ( 548) 3747 336.5 1.3e-91 NP_001230914 (OMIM: 164014) transcription factor p ( 448) 2853 259.6 1.5e-68 NP_001230913 (OMIM: 164014) transcription factor p ( 482) 2435 223.7 1e-57 XP_011543509 (OMIM: 164014) PREDICTED: transcripti ( 445) 1770 166.5 1.5e-40 XP_011543508 (OMIM: 164014) PREDICTED: transcripti ( 480) 1742 164.1 8.7e-40 NP_001278675 (OMIM: 164910) proto-oncogene c-Rel i ( 587) 1327 128.5 5.6e-29 XP_016860116 (OMIM: 164910) PREDICTED: proto-oncog ( 564) 1325 128.4 6.1e-29 NP_002899 (OMIM: 164910) proto-oncogene c-Rel isof ( 619) 1311 127.2 1.5e-28 XP_005259184 (OMIM: 604758) PREDICTED: transcripti ( 576) 1142 112.6 3.4e-24 NP_006500 (OMIM: 604758) transcription factor RelB ( 579) 1142 112.6 3.4e-24 XP_011531312 (OMIM: 164910) PREDICTED: proto-oncog ( 489) 851 87.6 1e-16 XP_005259185 (OMIM: 604758) PREDICTED: transcripti ( 507) 779 81.4 7.5e-15 XP_011538132 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 505 58.0 1.3e-07 XP_011538133 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 505 58.0 1.3e-07 NP_001309864 (OMIM: 164012,615577) nuclear factor ( 858) 397 48.7 8.7e-05 NP_001248332 (OMIM: 164012,615577) nuclear factor ( 899) 397 48.7 9.1e-05 NP_001275653 (OMIM: 164012,615577) nuclear factor ( 899) 397 48.7 9.1e-05 NP_002493 (OMIM: 164012,615577) nuclear factor NF- ( 899) 397 48.7 9.1e-05 NP_001309863 (OMIM: 164012,615577) nuclear factor ( 900) 397 48.7 9.1e-05 NP_001070962 (OMIM: 164012,615577) nuclear factor ( 900) 397 48.7 9.1e-05 XP_016871767 (OMIM: 164012,615577) PREDICTED: nucl (1081) 397 48.8 0.00011 XP_011530310 (OMIM: 164011,616576) PREDICTED: nucl ( 916) 358 45.4 0.00094 NP_003989 (OMIM: 164011,616576) nuclear factor NF- ( 969) 358 45.4 0.00098 NP_001158884 (OMIM: 164011,616576) nuclear factor ( 968) 357 45.3 0.001 NP_001306155 (OMIM: 164011,616576) nuclear factor ( 968) 357 45.3 0.001 XP_011530308 (OMIM: 164011,616576) PREDICTED: nucl ( 976) 357 45.3 0.0011 >>NP_068810 (OMIM: 164014) transcription factor p65 isof (551 aa) initn: 3783 init1: 3783 opt: 3783 Z-score: 1782.5 bits: 339.6 E(85289): 1.5e-92 Smith-Waterman score: 3783; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM 490 500 510 520 530 540 550 pF1KB7 DFSALLSQISS ::::::::::: NP_068 DFSALLSQISS 550 >>NP_001138610 (OMIM: 164014) transcription factor p65 i (548 aa) initn: 3749 init1: 2762 opt: 3747 Z-score: 1765.8 bits: 336.5 E(85289): 1.3e-91 Smith-Waterman score: 3747; 99.5% identity (99.5% similar) in 551 aa overlap (1-551:1-548) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS :::::::::::::::::::::: ::::::::::::::::::::::::::::::::::: NP_001 VKKRDLEQAISQRIQTNNNPFQ---EEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM 480 490 500 510 520 530 550 pF1KB7 DFSALLSQISS ::::::::::: NP_001 DFSALLSQISS 540 >>NP_001230914 (OMIM: 164014) transcription factor p65 i (448 aa) initn: 2987 init1: 2817 opt: 2853 Z-score: 1351.8 bits: 259.6 E(85289): 1.5e-68 Smith-Waterman score: 2885; 81.3% identity (81.3% similar) in 551 aa overlap (1-551:1-448) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA ::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQ--------------- 370 380 390 400 430 440 450 460 470 480 pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ NP_001 ------------------------------------------------------------ 490 500 510 520 530 540 pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM :::::::::::::::::::::::::::::::: NP_001 ----------------------------RPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM 410 420 430 550 pF1KB7 DFSALLSQISS ::::::::::: NP_001 DFSALLSQISS 440 >>NP_001230913 (OMIM: 164014) transcription factor p65 i (482 aa) initn: 2503 init1: 2422 opt: 2435 Z-score: 1157.2 bits: 223.7 E(85289): 1e-57 Smith-Waterman score: 3170; 87.5% identity (87.5% similar) in 551 aa overlap (1-551:1-482) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY :::::::::::::::::::::::::::::::::::::::::::: NP_001 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKP---------------- 310 320 330 340 370 380 390 400 410 420 pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA ::::::: NP_001 -----------------------------------------------------APGPPQA 350 430 440 450 460 470 480 pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ 360 370 380 390 400 410 490 500 510 520 530 540 pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM 420 430 440 450 460 470 550 pF1KB7 DFSALLSQISS ::::::::::: NP_001 DFSALLSQISS 480 >>XP_011543509 (OMIM: 164014) PREDICTED: transcription f (445 aa) initn: 1741 init1: 1741 opt: 1770 Z-score: 848.8 bits: 166.5 E(85289): 1.5e-40 Smith-Waterman score: 2823; 80.6% identity (80.8% similar) in 551 aa overlap (1-551:1-445) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS ::::::. XP_011 HPIFDNH----------------------------------------------------- 250 260 270 280 290 300 pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE ::::::: XP_011 -----------------------------------------------------DRHRIEE 190 310 320 330 340 350 360 pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY 200 210 220 230 240 250 370 380 390 400 410 420 pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA 260 270 280 290 300 310 430 440 450 460 470 480 pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ 320 330 340 350 360 370 490 500 510 520 530 540 pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM 380 390 400 410 420 430 550 pF1KB7 DFSALLSQISS ::::::::::: XP_011 DFSALLSQISS 440 >>XP_011543508 (OMIM: 164014) PREDICTED: transcription f (480 aa) initn: 1742 init1: 1742 opt: 1742 Z-score: 835.3 bits: 164.1 E(85289): 8.7e-40 Smith-Waterman score: 3142; 87.1% identity (87.1% similar) in 551 aa overlap (1-551:1-480) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS ::::::::::::::::::::::::::::::::::::::::: XP_011 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQK------------------- 190 200 210 220 250 260 270 280 290 300 pF1KB7 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE :::::::: XP_011 ----------------------------------------------------DDRHRIEE 310 320 330 340 350 360 pF1KB7 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB7 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB7 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB7 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM 410 420 430 440 450 460 550 pF1KB7 DFSALLSQISS ::::::::::: XP_011 DFSALLSQISS 470 480 >>NP_001278675 (OMIM: 164910) proto-oncogene c-Rel isofo (587 aa) initn: 1095 init1: 613 opt: 1327 Z-score: 641.2 bits: 128.5 E(85289): 5.6e-29 Smith-Waterman score: 1327; 46.9% identity (70.9% similar) in 461 aa overlap (16-465:5-461) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT : .::.::::::.:::::::::::::::::::::.:::...:.:. NP_001 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS 10 20 30 40 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.: NP_001 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC 50 60 70 80 90 100 130 140 150 160 170 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP :::.....:: ::... :::.:: :.: .: :::.::::::: . : : :: NP_001 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR ::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::. NP_001 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH : ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : . NP_001 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 RIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQP---YPFTS . :...: :... . . . : ::: .: . :. . . . NP_001 GNKAKKQKTTLLFQKLCQ-DHVNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMPT 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 SLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQ-APAPVPV ..:. . .:. :. .:. ...:: : . .. :.: . .. :.. . .: NP_001 GVSSQAESYYPSPGPISSGLSHHASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPS 350 360 370 380 390 400 420 430 440 450 460 pF1KB7 LAPGPPQAVAPPAPKPTQAGEGTL---SEALLQLQFDDEDLGALLGNSTDPAVFTDLASV . : : . :. . .:... . .. .. .. .. . : : : :: .... NP_001 NSQGIPPFLRIPVGNDLNASNACIYNNADDIVGMEASSMPSADLYGIS-DPNMLSNCSVN 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB7 DNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLS NP_001 MMTTSSDSMGETDNPRLLSMNLENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVS 470 480 490 500 510 520 >>XP_016860116 (OMIM: 164910) PREDICTED: proto-oncogene (564 aa) initn: 1231 init1: 613 opt: 1325 Z-score: 640.6 bits: 128.4 E(85289): 6.1e-29 Smith-Waterman score: 1325; 52.7% identity (74.4% similar) in 387 aa overlap (16-395:5-389) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT : .::.::::::.:::::::::::::::::::::.:::...:.:. XP_016 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS 10 20 30 40 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.: XP_016 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC 50 60 70 80 90 100 130 140 150 160 170 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP :::.....:: ::... :::.:: :.: .: :::.::::::: . : : :: XP_016 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR ::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::. XP_016 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH : ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : . XP_016 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 RIEEKRKRTYETFKSIMK-KSP--FSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTS . :...: :... . . : :: . : : .. ..: : : . . XP_016 GNKAKKQKTTLLFQKLCQDHEPNLFSHDAVVREMPTGVSSQAESYYPSPGPISSGLSHHA 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 SLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVL :.. . . . ... :. . .... :. ..::. : XP_016 SMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVGNDLNASNACI 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB7 APGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSE XP_016 YNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNPRLLSMNLENP 410 420 430 440 450 460 >>NP_002899 (OMIM: 164910) proto-oncogene c-Rel isoform (619 aa) initn: 1095 init1: 613 opt: 1311 Z-score: 633.5 bits: 127.2 E(85289): 1.5e-28 Smith-Waterman score: 1314; 50.0% identity (70.9% similar) in 426 aa overlap (16-427:5-421) 10 20 30 40 50 60 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT : .::.::::::.:::::::::::::::::::::.:::...:.:. NP_002 MASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPS 10 20 30 40 70 80 90 100 110 120 pF1KB7 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC :.: .: : : :::.::::. :..::::.:::::::::.::::. .: ::::::.: NP_002 IQIMNYYGKGKVRITLVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRC 50 60 70 80 90 100 130 140 150 160 170 pF1KB7 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDY---DLNAVRLCFQVTVRDPSGR-PLRLP :::.....:: ::... :::.:: :.: .: :::.::::::: . : : :: NP_002 VKKKEVKEAIITRIKAGINPFNVP-EKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALP 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 PVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEAR ::.:.::.::::::::::.:::::.: :: ::::::::::::::.:::: :. :::. NP_002 PVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAK 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 GSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRH : ::::::::::::::.:::: .. :: :.::::::::.:.:: :.:.:::: : . NP_002 GIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTY 230 240 250 260 270 280 300 310 320 330 340 pF1KB7 RIEEKRKRTYETFKSIMKKSPFSG--PTDPR--------PPPRRIAVPSRSSASVPKPAP . :...: :... . .: .: :: . . ... :. : NP_002 GNKAKKQKTTLLFQKLCQDHVETGFRHVDQDGLELLTSGDPPTLASQSAGITVNFPE-RP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB7 QPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQA .: . : . . :.. .:. ... : : :: . :.:. .:. . NP_002 RPGLLGSIGEGRYFKKEPNL------FSHDAVVREMPTGVSSQAESYYPSPGPISSGLSH 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB7 PAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDL : . : . ..:: :.:. NP_002 HASMAPLPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIPVGNDLNASNA 410 420 430 440 450 460 >>XP_005259184 (OMIM: 604758) PREDICTED: transcription f (576 aa) initn: 1080 init1: 736 opt: 1142 Z-score: 555.4 bits: 112.6 E(85289): 3.4e-24 Smith-Waterman score: 1142; 42.4% identity (68.4% similar) in 446 aa overlap (7-436:111-549) 10 20 30 pF1KB7 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRY :. :: :. . :.. : :::::::::::: XP_005 SRGAASLSTVTLGPVAPPATPPPWGCPLGRLVSPA-PGPGPQPHLVITEQPKQRGMRFRY 90 100 110 120 130 40 50 60 70 80 90 pF1KB7 KCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRIS--LVTKDPPHRPHPHELVGKD .::::::::: :: ::...:: :.:.. : :... :: :: ::: ::: ::::: XP_005 ECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKD 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB7 CRDGFYEAELCPDRCI-HSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYD : ::. ...: : :::.:::::::.:...: :: ..:: . .:... ... . : XP_005 CTDGICRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVD 200 210 220 230 240 250 160 170 180 190 200 210 pF1KB7 LNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIF .:.::.:::.. :: .:. :. ::::.:..:... ::.::.:::.:..:: : ::.:.. XP_005 MNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELY 260 270 280 290 300 310 220 230 240 250 260 270 pF1KB7 LLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLR ::::::::::: : :. .::.:..:::::::::.::::.:::: : . :: :.. :. XP_005 LLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQ 320 330 340 350 360 370 280 290 300 310 320 pF1KB7 RPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPR----PPPR : .: :::. : ::: : . ...:::: . . ...: : . : : XP_005 RLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGMPDVLGELNSSDPHGIESKRRKKKPAIL 380 390 400 410 420 430 330 340 350 360 370 380 pF1KB7 RIAVPSRSSASVPKPA---PQPYPFTSSLSTINYDEFPTMVFPSGQ--ISQASALAPAPP .:...:. :. :.: :....: .: . :.: .... : :. : XP_005 DHFLPNHGSGPFLPPSALLPDPDFFSGTVS------LPGLEPPGGPDLLDDGFAYDPTAP 440 450 460 470 480 490 390 400 410 420 430 440 pF1KB7 QVLPQAPAPAPAPAMVSALAQAPAPVPVLA--PGP-PQAV-APPAPKPTQAGEGTLSEAL .. . ::: .::.. . . :.. ::: : .. . :: : ..: ..: XP_005 TLFTMLDLLPPAPPHASAVVCSGGAGAVVGETPGPEPLTLDSYQAPGPGDGGTASLVGSN 500 510 520 530 540 550 450 460 470 480 490 500 pF1KB7 LQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAI XP_005 MFPNHYREAAFGGGLLSPGPEAT 560 570 551 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:09:01 2016 done: Fri Nov 4 21:09:02 2016 Total Scan time: 10.830 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]