FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7860, 599 aa 1>>>pF1KB7860 599 - 599 aa - 599 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5273+/-0.000657; mu= 10.2469+/- 0.040 mean_var=314.1875+/-67.161, 0's: 0 Z-trim(114.2): 2010 B-trim: 96 in 1/50 Lambda= 0.072357 statistics sampled from 21642 (23964) to 21642 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.281), width: 16 Scan time: 9.280 The best scores are: opt bits E(85289) NP_001287752 (OMIM: 614161,614170) PR domain zinc ( 599) 4203 453.8 7.7e-127 NP_001287753 (OMIM: 614161,614170) PR domain zinc ( 501) 3355 365.1 3.1e-100 NP_061169 (OMIM: 614161,614170) PR domain zinc fin ( 630) 2798 307.1 1.1e-82 XP_011529865 (OMIM: 614161,614170) PREDICTED: PR d ( 610) 2140 238.4 5.2e-62 XP_016863157 (OMIM: 614161,614170) PREDICTED: PR d ( 615) 2089 233.1 2.1e-60 XP_011529864 (OMIM: 614161,614170) PREDICTED: PR d ( 641) 2089 233.1 2.2e-60 XP_011529872 (OMIM: 614161,614170) PREDICTED: PR d ( 403) 2083 232.2 2.6e-60 XP_016863160 (OMIM: 614161,614170) PREDICTED: PR d ( 316) 2070 230.7 5.8e-60 XP_016863159 (OMIM: 614161,614170) PREDICTED: PR d ( 532) 1950 218.5 4.6e-56 XP_016863158 (OMIM: 614161,614170) PREDICTED: PR d ( 532) 1950 218.5 4.6e-56 XP_011529866 (OMIM: 614161,614170) PREDICTED: PR d ( 606) 1905 213.9 1.3e-54 XP_011529867 (OMIM: 614161,614170) PREDICTED: PR d ( 589) 1704 192.9 2.6e-48 XP_011529868 (OMIM: 614161,614170) PREDICTED: PR d ( 589) 1704 192.9 2.6e-48 XP_005262765 (OMIM: 614161,614170) PREDICTED: PR d ( 346) 1623 184.1 6.8e-46 XP_011529870 (OMIM: 614161,614170) PREDICTED: PR d ( 543) 1623 184.4 8.7e-46 XP_011529871 (OMIM: 614161,614170) PREDICTED: PR d ( 543) 1623 184.4 8.7e-46 XP_011529869 (OMIM: 614161,614170) PREDICTED: PR d ( 543) 1623 184.4 8.7e-46 XP_006722943 (OMIM: 603971) PREDICTED: zinc finger (1092) 1135 133.9 2.7e-30 XP_011526568 (OMIM: 603971) PREDICTED: zinc finger (1092) 1135 133.9 2.7e-30 XP_016882725 (OMIM: 603971) PREDICTED: zinc finger (1118) 1135 133.9 2.8e-30 XP_011526567 (OMIM: 603971) PREDICTED: zinc finger (1150) 1135 133.9 2.8e-30 XP_016882724 (OMIM: 603971) PREDICTED: zinc finger (1150) 1135 133.9 2.8e-30 NP_001287880 (OMIM: 603971) zinc finger protein 91 (1159) 1135 133.9 2.8e-30 NP_003421 (OMIM: 603971) zinc finger protein 91 is (1191) 1135 134.0 2.9e-30 NP_112495 (OMIM: 603975) zinc finger protein 93 [H ( 620) 1117 131.6 7.4e-30 XP_016882746 (OMIM: 603977) PREDICTED: zinc finger (1168) 1111 131.4 1.6e-29 NP_009084 (OMIM: 603977) zinc finger protein 208 i (1280) 1111 131.5 1.7e-29 XP_016882723 (OMIM: 603899) PREDICTED: zinc finger ( 518) 1082 127.9 8.5e-29 NP_001243102 (OMIM: 603899) zinc finger protein 85 ( 531) 1082 127.9 8.6e-29 XP_011526566 (OMIM: 603899) PREDICTED: zinc finger ( 536) 1082 127.9 8.6e-29 NP_003420 (OMIM: 603899) zinc finger protein 85 is ( 595) 1082 128.0 9.1e-29 NP_001243100 (OMIM: 603899) zinc finger protein 85 ( 625) 1082 128.0 9.4e-29 XP_011526565 (OMIM: 603899) PREDICTED: zinc finger ( 640) 1082 128.0 9.5e-29 NP_001252517 (OMIM: 604752) zinc finger protein 26 ( 711) 1080 127.9 1.2e-28 NP_003405 (OMIM: 604752) zinc finger protein 267 i ( 743) 1080 127.9 1.2e-28 XP_016878355 (OMIM: 604752) PREDICTED: zinc finger ( 487) 1074 127.0 1.5e-28 XP_005259469 (OMIM: 604749) PREDICTED: zinc finger ( 734) 1077 127.6 1.5e-28 NP_004225 (OMIM: 604749) zinc finger protein 235 [ ( 738) 1077 127.6 1.5e-28 XP_016878354 (OMIM: 604752) PREDICTED: zinc finger ( 711) 1074 127.2 1.8e-28 NP_001291423 (OMIM: 194527) zinc finger protein 23 ( 585) 1066 126.3 2.9e-28 NP_001291422 (OMIM: 194527) zinc finger protein 23 ( 585) 1066 126.3 2.9e-28 NP_666016 (OMIM: 194527) zinc finger protein 23 is ( 643) 1066 126.3 3e-28 NP_001291421 (OMIM: 194527) zinc finger protein 23 ( 643) 1066 126.3 3e-28 NP_001309068 (OMIM: 600398) zinc finger protein 16 ( 782) 1066 126.5 3.4e-28 NP_001309066 (OMIM: 600398) zinc finger protein 16 ( 782) 1066 126.5 3.4e-28 NP_001309067 (OMIM: 600398) zinc finger protein 16 ( 782) 1066 126.5 3.4e-28 NP_001152765 (OMIM: 603984) zinc finger protein 73 ( 536) 1063 125.9 3.4e-28 NP_001309061 (OMIM: 600398) zinc finger protein 16 ( 818) 1066 126.5 3.5e-28 NP_001309063 (OMIM: 600398) zinc finger protein 16 ( 818) 1066 126.5 3.5e-28 NP_942596 (OMIM: 600398) zinc finger protein 160 i ( 818) 1066 126.5 3.5e-28 >>NP_001287752 (OMIM: 614161,614170) PR domain zinc fing (599 aa) initn: 4203 init1: 4203 opt: 4203 Z-score: 2398.1 bits: 453.8 E(85289): 7.7e-127 Smith-Waterman score: 4203; 100.0% identity (100.0% similar) in 599 aa overlap (1-599:1-599) 10 20 30 40 50 60 pF1KB7 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHFEQHQETCRGDARFVCKADSCGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHFEQHQETCRGDARFVCKADSCGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RLKSKDALKRHQENVHTGDPKKKLICSVCNKKCSSASSLQEHRKIHEIFDCQECMKKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLKSKDALKRHQENVHTGDPKKKLICSVCNKKCSSASSLQEHRKIHEIFDCQECMKKFIS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 ANQLKRHMITHSEKRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANQLKRHMITHSEKRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KNHKKTHSEERPFQCEECKALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNHKKTHSEERPFQCEECKALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 TGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEK 490 500 510 520 530 540 550 560 570 580 590 pF1KB7 PFQCDVCDLAFSLKKMLIRHKMTHNPNRPLAECQFCHKKFTRNDYLKVHMDNIHGVADS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFQCDVCDLAFSLKKMLIRHKMTHNPNRPLAECQFCHKKFTRNDYLKVHMDNIHGVADS 550 560 570 580 590 >>NP_001287753 (OMIM: 614161,614170) PR domain zinc fing (501 aa) initn: 3355 init1: 3355 opt: 3355 Z-score: 1920.5 bits: 365.1 E(85289): 3.1e-100 Smith-Waterman score: 3355; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483) 10 20 30 40 50 60 pF1KB7 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHFEQHQETCRGDARFVCKADSCGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHFEQHQETCRGDARFVCKADSCGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RLKSKDALKRHQENVHTGDPKKKLICSVCNKKCSSASSLQEHRKIHEIFDCQECMKKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLKSKDALKRHQENVHTGDPKKKLICSVCNKKCSSASSLQEHRKIHEIFDCQECMKKFIS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 ANQLKRHMITHSEKRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANQLKRHMITHSEKRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KNHKKTHSEERPFQCEECKALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNHKKTHSEERPFQCEECKALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 TGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEK ::: NP_001 TGEAVQVLRVQQGLQPEARPG 490 500 >>NP_061169 (OMIM: 614161,614170) PR domain zinc finger (630 aa) initn: 2739 init1: 2739 opt: 2798 Z-score: 1605.3 bits: 307.1 E(85289): 1.1e-82 Smith-Waterman score: 4131; 95.1% identity (95.1% similar) in 630 aa overlap (1-599:1-630) 10 20 30 40 50 60 pF1KB7 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED 130 140 150 160 170 180 190 200 210 pF1KB7 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRH----------------------- ::::::::::::::::::::::::::::::::::::: NP_061 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHVLQCTAKSSLKESSRSFQCSVCN 190 200 210 220 230 240 220 230 240 250 260 pF1KB7 --------FEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SSFSSASSFEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSEKRPYNCEICNKSFKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSEKRPYNCEICNKSFKRL 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB7 DQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQ 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 RHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 RHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHK 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB7 KTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 KTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHT 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB7 REKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 REKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRP 550 560 570 580 590 600 570 580 590 pF1KB7 LAECQFCHKKFTRNDYLKVHMDNIHGVADS :::::::::::::::::::::::::::::: NP_061 LAECQFCHKKFTRNDYLKVHMDNIHGVADS 610 620 630 >>XP_011529865 (OMIM: 614161,614170) PREDICTED: PR domai (610 aa) initn: 4196 init1: 2140 opt: 2140 Z-score: 1234.2 bits: 238.4 E(85289): 5.2e-62 Smith-Waterman score: 4171; 98.2% identity (98.2% similar) in 610 aa overlap (1-599:1-610) 10 20 30 40 50 60 pF1KB7 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHFEQHQETCRGDARFVCKADSCGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHFEQHQETCRGDARFVCKADSCGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RLKSKDALKRHQENVHTGDPKKKLICSVCNKKCSSASSLQEHRKIHEIFDCQECMKKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLKSKDALKRHQENVHTGDPKKKLICSVCNKKCSSASSLQEHRKIHEIFDCQECMKKFIS 250 260 270 280 290 300 310 320 330 340 pF1KB7 ANQLKRHMITHS-----------EKRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYKCKL :::::::::::: ::::::::::::::::::::::::::::::::::::: XP_011 ANQLKRHMITHSDMRLSPLIFLIEKRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYKCKL 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB7 CGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQRHLLIHNSERTFKCHHCDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQRHLLIHNSERTFKCHHCDAT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB7 FKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKFAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKFAS 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB7 SGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYKCSECSKAFSQKRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYKCSECSKAFSQKRGL 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB7 DEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRPLAECQFCHKKFTRNDYLKVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRPLAECQFCHKKFTRNDYLKVH 550 560 570 580 590 600 590 pF1KB7 MDNIHGVADS :::::::::: XP_011 MDNIHGVADS 610 >>XP_016863157 (OMIM: 614161,614170) PREDICTED: PR domai (615 aa) initn: 3984 init1: 2070 opt: 2089 Z-score: 1205.4 bits: 233.1 E(85289): 2.1e-60 Smith-Waterman score: 3898; 92.7% identity (93.0% similar) in 613 aa overlap (29-599:3-615) 10 20 30 40 50 60 pF1KB7 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV . .::::::::::::::::::::::::::::: XP_016 MLIFQGEKFGPFAGEKRMPEDLDENMDYRLMWEV 10 20 30 70 80 90 100 110 120 pF1KB7 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED 100 110 120 130 140 150 190 200 210 pF1KB7 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRH----------------------- ::::::::::::::::::::::::::::::::::::: XP_016 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHVLQCTAKSSLKESSRSFQCSVCN 160 170 180 190 200 210 220 230 240 250 260 pF1KB7 --------FEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFSSASSFEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC 220 230 240 250 260 270 270 280 290 300 310 pF1KB7 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHS-----------EKRPYN ::::::::::::::::::::::::::::::::::::::::::: :::::: XP_016 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSDMRLSPLIFLIEKRPYN 280 290 300 310 320 330 320 330 340 350 360 370 pF1KB7 CEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEEC 340 350 360 370 380 390 380 390 400 410 420 430 pF1KB7 KALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKA 400 410 420 430 440 450 440 450 460 470 480 490 pF1KB7 FVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKN 460 470 480 490 500 510 500 510 520 530 540 550 pF1KB7 DGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLI 520 530 540 550 560 570 560 570 580 590 pF1KB7 RHKMTHNPNRPLAECQFCHKKFTRNDYLKVHMDNIHGVADS ::::::::::::::::::::::::::::::::::::::::: XP_016 RHKMTHNPNRPLAECQFCHKKFTRNDYLKVHMDNIHGVADS 580 590 600 610 >>XP_011529864 (OMIM: 614161,614170) PREDICTED: PR domai (641 aa) initn: 4185 init1: 2070 opt: 2089 Z-score: 1205.2 bits: 233.1 E(85289): 2.2e-60 Smith-Waterman score: 4026; 93.3% identity (93.3% similar) in 631 aa overlap (11-599:11-641) 10 20 30 40 50 60 pF1KB7 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED 130 140 150 160 170 180 190 200 210 pF1KB7 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRH----------------------- ::::::::::::::::::::::::::::::::::::: XP_011 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHVLQCTAKSSLKESSRSFQCSVCN 190 200 210 220 230 240 220 230 240 250 260 pF1KB7 --------FEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSFSSASSFEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC 250 260 270 280 290 300 270 280 290 300 310 pF1KB7 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHS-----------EKRPYN ::::::::::::::::::::::::::::::::::::::::::: :::::: XP_011 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSDMRLSPLIFLIEKRPYN 310 320 330 340 350 360 320 330 340 350 360 370 pF1KB7 CEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEEC 370 380 390 400 410 420 380 390 400 410 420 430 pF1KB7 KALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKA 430 440 450 460 470 480 440 450 460 470 480 490 pF1KB7 FVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKN 490 500 510 520 530 540 500 510 520 530 540 550 pF1KB7 DGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLI 550 560 570 580 590 600 560 570 580 590 pF1KB7 RHKMTHNPNRPLAECQFCHKKFTRNDYLKVHMDNIHGVADS ::::::::::::::::::::::::::::::::::::::::: XP_011 RHKMTHNPNRPLAECQFCHKKFTRNDYLKVHMDNIHGVADS 610 620 630 640 >>XP_011529872 (OMIM: 614161,614170) PREDICTED: PR domai (403 aa) initn: 2440 init1: 2070 opt: 2083 Z-score: 1203.8 bits: 232.2 E(85289): 2.6e-60 Smith-Waterman score: 2415; 96.9% identity (96.9% similar) in 352 aa overlap (259-599:52-403) 230 240 250 260 270 280 pF1KB7 ARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVCNKKCSSASSLQEHRKIHEI :::::::::::::::::::::::::::::: XP_011 HCTRNPQRRKNLSARTVGRNSQLSRLCKDRDPKKKLICSVCNKKCSSASSLQEHRKIHEI 30 40 50 60 70 80 290 300 310 320 330 pF1KB7 FDCQECMKKFISANQLKRHMITHS-----------EKRPYNCEICNKSFKRLDQVGAHKV :::::::::::::::::::::::: ::::::::::::::::::::::::: XP_011 FDCQECMKKFISANQLKRHMITHSDMRLSPLIFLIEKRPYNCEICNKSFKRLDQVGAHKV 90 100 110 120 130 140 340 350 360 370 380 390 pF1KB7 IHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQRHLLIHNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQRHLLIHNS 150 160 170 180 190 200 400 410 420 430 440 450 pF1KB7 ERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKE 210 220 230 240 250 260 460 470 480 490 500 510 pF1KB7 KICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYKCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYKCS 270 280 290 300 310 320 520 530 540 550 560 570 pF1KB7 ECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRPLAECQFCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRPLAECQFCH 330 340 350 360 370 380 580 590 pF1KB7 KKFTRNDYLKVHMDNIHGVADS :::::::::::::::::::::: XP_011 KKFTRNDYLKVHMDNIHGVADS 390 400 >>XP_016863160 (OMIM: 614161,614170) PREDICTED: PR domai (316 aa) initn: 2179 init1: 2070 opt: 2070 Z-score: 1197.5 bits: 230.7 E(85289): 5.8e-60 Smith-Waterman score: 2154; 96.5% identity (96.5% similar) in 316 aa overlap (295-599:1-316) 270 280 290 300 310 pF1KB7 ICSVCNKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHS-----------E :::::::::::::::::: : XP_016 MKKFISANQLKRHMITHSDMRLSPLIFLIE 10 20 30 320 330 340 350 360 370 pF1KB7 KRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPF 40 50 60 70 80 90 380 390 400 410 420 430 pF1KB7 QCEECKALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCEECKALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCE 100 110 120 130 140 150 440 450 460 470 480 490 pF1KB7 LCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEK 160 170 180 190 200 210 500 510 520 530 540 550 pF1KB7 GFSKNDGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFSKNDGLKMHIRTHTREKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSL 220 230 240 250 260 270 560 570 580 590 pF1KB7 KKMLIRHKMTHNPNRPLAECQFCHKKFTRNDYLKVHMDNIHGVADS :::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKMLIRHKMTHNPNRPLAECQFCHKKFTRNDYLKVHMDNIHGVADS 280 290 300 310 >>XP_016863159 (OMIM: 614161,614170) PREDICTED: PR domai (532 aa) initn: 2143 init1: 1891 opt: 1950 Z-score: 1127.6 bits: 218.5 E(85289): 4.6e-56 Smith-Waterman score: 3283; 94.0% identity (94.0% similar) in 514 aa overlap (1-483:1-514) 10 20 30 40 50 60 pF1KB7 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED 130 140 150 160 170 180 190 200 210 pF1KB7 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRH----------------------- ::::::::::::::::::::::::::::::::::::: XP_016 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHVLQCTAKSSLKESSRSFQCSVCN 190 200 210 220 230 240 220 230 240 250 260 pF1KB7 --------FEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFSSASSFEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSEKRPYNCEICNKSFKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSEKRPYNCEICNKSFKRL 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB7 DQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQ 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 RHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHK 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB7 KTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHT :::::::::::::::::::::::::::::::::: XP_016 KTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGEAVQVLRVQQGLQPEARPG 490 500 510 520 530 510 520 530 540 550 560 pF1KB7 REKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRP >>XP_016863158 (OMIM: 614161,614170) PREDICTED: PR domai (532 aa) initn: 2143 init1: 1891 opt: 1950 Z-score: 1127.6 bits: 218.5 E(85289): 4.6e-56 Smith-Waterman score: 3283; 94.0% identity (94.0% similar) in 514 aa overlap (1-483:1-514) 10 20 30 40 50 60 pF1KB7 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGMYVPDRFSLKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQEQKNLAAIQEGENIFYLAVEDIETDTELL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESSFTSED 130 140 150 160 170 180 190 200 210 pF1KB7 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRH----------------------- ::::::::::::::::::::::::::::::::::::: XP_016 ILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHVLQCTAKSSLKESSRSFQCSVCN 190 200 210 220 230 240 220 230 240 250 260 pF1KB7 --------FEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFSSASSFEQHQETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVC 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSEKRPYNCEICNKSFKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKKCSSASSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSEKRPYNCEICNKSFKRL 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB7 DQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQVGAHKVIHSEDKPYKCKLCGKGFAHRNVYKNHKKTHSEERPFQCEECKALFRTPFSLQ 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 RHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHK 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB7 KTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHT :::::::::::::::::::::::::::::::::: XP_016 KTHTGEKEKICPYCGQKFASSGTLRVHIRSHTGEAVQVLRVQQGLQPEARPG 490 500 510 520 530 510 520 530 540 550 560 pF1KB7 REKPYKCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRP 599 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:11:07 2016 done: Fri Nov 4 21:11:09 2016 Total Scan time: 9.280 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]