FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7867, 560 aa 1>>>pF1KB7867 560 - 560 aa - 560 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.7482+/-0.000359; mu= -1.0494+/- 0.022 mean_var=256.3563+/-52.859, 0's: 0 Z-trim(122.6): 30 B-trim: 632 in 2/55 Lambda= 0.080104 statistics sampled from 40960 (40994) to 40960 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.481), width: 16 Scan time: 12.090 The best scores are: opt bits E(85289) NP_003646 (OMIM: 603079) E3 SUMO-protein ligase CB ( 560) 3871 460.5 6.4e-129 XP_011523701 (OMIM: 603079) PREDICTED: E3 SUMO-pro ( 494) 3419 408.2 3.1e-113 NP_783640 (OMIM: 608457) chromobox protein homolog ( 251) 447 64.5 4.5e-10 XP_005261470 (OMIM: 608457) PREDICTED: chromobox p ( 158) 433 62.8 9.5e-10 XP_016884168 (OMIM: 608457) PREDICTED: chromobox p ( 250) 437 63.4 9.9e-10 NP_005180 (OMIM: 602770,613080) chromobox protein ( 532) 442 64.2 1.2e-09 XP_011523684 (OMIM: 602770,613080) PREDICTED: chro ( 586) 442 64.2 1.3e-09 XP_006724240 (OMIM: 608457) PREDICTED: chromobox p ( 192) 427 62.1 1.8e-09 XP_011528327 (OMIM: 608457) PREDICTED: chromobox p ( 165) 407 59.8 7.9e-09 XP_006724241 (OMIM: 608457) PREDICTED: chromobox p ( 166) 407 59.8 7.9e-09 XP_006724238 (OMIM: 608457) PREDICTED: chromobox p ( 258) 406 59.8 1.2e-08 XP_006724237 (OMIM: 608457) PREDICTED: chromobox p ( 259) 406 59.8 1.2e-08 XP_006724239 (OMIM: 608457) PREDICTED: chromobox p ( 200) 401 59.2 1.5e-08 NP_116036 (OMIM: 602770,613080) chromobox protein ( 211) 385 57.3 5.6e-08 >>NP_003646 (OMIM: 603079) E3 SUMO-protein ligase CBX4 [ (560 aa) initn: 3871 init1: 3871 opt: 3871 Z-score: 2435.5 bits: 460.5 E(85289): 6.4e-129 Smith-Waterman score: 3871; 100.0% identity (100.0% similar) in 560 aa overlap (1-560:1-560) 10 20 30 40 50 60 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAPKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAPKEA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 VTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAAD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 ERHPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVSDPQPQDAGSRKLSPTKEAFGEQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ERHPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVSDPQPQDAGSRKLSPTKEAFGEQPL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHHAVGLNLSHVRKRCLSETHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHHAVGLNLSHVRKRCLSETHGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 REPCKKRLTARSISTPTCLGGSPAAERPADLPPAAALPQPEVILLDSDLDEPIDLRCVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 REPCKKRLTARSISTPTCLGGSPAAERPADLPPAAALPQPEVILLDSDLDEPIDLRCVKT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 RSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPAEAQDEPAESLSEFKPFFGNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPAEAQDEPAESLSEFKPFFGNI 490 500 510 520 530 540 550 560 pF1KB7 IITDVTANCLTVTFKEYVTV :::::::::::::::::::: NP_003 IITDVTANCLTVTFKEYVTV 550 560 >>XP_011523701 (OMIM: 603079) PREDICTED: E3 SUMO-protein (494 aa) initn: 3419 init1: 3419 opt: 3419 Z-score: 2154.0 bits: 408.2 E(85289): 3.1e-113 Smith-Waterman score: 3419; 100.0% identity (100.0% similar) in 494 aa overlap (67-560:1-494) 40 50 60 70 80 90 pF1KB7 PKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGL :::::::::::::::::::::::::::::: XP_011 MGYRKRGPKPKPLVVQVPTFARRSNVLTGL 10 20 30 100 110 120 130 140 150 pF1KB7 QDSSTDNRAKLDLGAQGKGQGHQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDSSTDNRAKLDLGAQGKGQGHQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB7 KKHHPYQPDPKMYDLQYQGGHKEAPSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKHHPYQPDPKMYDLQYQGGHKEAPSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB7 AAGAPGKGSEKGPPNGMMPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGAPGKGSEKGPPNGMMPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQA 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB7 VKIKSGEVAEGEARSPSHKKRAADERHPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKIKSGEVAEGEARSPSHKKRAADERHPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVS 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB7 DPQPQDAGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPQPQDAGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHH 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB7 HHHHAVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAERPADLPPAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHHHAVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAERPADLPPAAA 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB7 LPQPEVILLDSDLDEPIDLRCVKTRSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPQPEVILLDSDLDEPIDLRCVKTRSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAE 400 410 420 430 440 450 520 530 540 550 560 pF1KB7 KPPAEAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV :::::::::::::::::::::::::::::::::::::::::::: XP_011 KPPAEAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV 460 470 480 490 >>NP_783640 (OMIM: 608457) chromobox protein homolog 7 [ (251 aa) initn: 505 init1: 426 opt: 447 Z-score: 301.9 bits: 64.5 E(85289): 4.5e-10 Smith-Waterman score: 447; 39.0% identity (63.8% similar) in 213 aa overlap (1-206:1-207) 10 20 30 40 50 60 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR ::: :.::.:::::::.:::.:::.:::::::.:: :::.::::::.::::::..:.... NP_783 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ERQEQLMGYRKRGPKPKPLVVQ--VPTFARRSNVLTGLQDSSTDNRAKLDLGA-QGKGQG :.... :::::::::: :..: : :. : . . : :. .: .. NP_783 EERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 HQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGH :: .: : :: .... : .:. :: : :. . .. . . NP_783 GAPELVDKG--PLVPTLPFPLRKP----RKAHKYLRLSRKKFPPRGPNLESHSHRRELFL 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 KEAPSPTCPDLGAK----SHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGM .: :.: . ... ..::.. :.. :.: NP_783 QEPPAPDVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 MPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPS NP_783 REAQAAEGFFRDRSGKF 240 250 >>XP_005261470 (OMIM: 608457) PREDICTED: chromobox prote (158 aa) initn: 507 init1: 433 opt: 433 Z-score: 296.0 bits: 62.8 E(85289): 9.5e-10 Smith-Waterman score: 433; 69.0% identity (92.9% similar) in 84 aa overlap (1-84:1-84) 10 20 30 40 50 60 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR ::: :.::.:::::::.:::.:::.:::::::.:: :::.::::::.::::::..:.... XP_005 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY :.... :::::::::: :..: : XP_005 EERDRASGYRKRGPKPKRLLLQEPPAPDVLQAAGEWEPAAQPPEEEADADLAEGPPPWTP 70 80 90 100 110 120 >>XP_016884168 (OMIM: 608457) PREDICTED: chromobox prote (250 aa) initn: 508 init1: 426 opt: 437 Z-score: 295.7 bits: 63.4 E(85289): 9.9e-10 Smith-Waterman score: 437; 41.9% identity (64.5% similar) in 186 aa overlap (1-183:1-180) 10 20 30 40 50 60 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR ::: :.::.:::::::.:::.:::.:::::::.:: :::.::::::.::::::..:.... XP_016 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 ERQEQLMGYRKRGPKPKPLVVQ--VPTFARRSNVLTGLQDSSTDNRAKLDLGA-QGKGQG :.... :::::::::: :..: : :. : . . : :. .: .. XP_016 EERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 HQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGH :: .: : :: .... : .:. :: : :. . .. . . XP_016 GAPELVDKG--PLVPTLPFPLRKP----RKAHKYLRLSRKKFPPRGPNLESHSHRRELFL 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 KEAPSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAP .: :.: XP_016 QEPPAPDVLQAAGEWEPAAQPPEEEDADLAEGPPPWTPALPSSEVTVTDITANSITVTFR 180 190 200 210 220 230 >>NP_005180 (OMIM: 602770,613080) chromobox protein homo (532 aa) initn: 474 init1: 329 opt: 442 Z-score: 294.2 bits: 64.2 E(85289): 1.2e-09 Smith-Waterman score: 486; 27.4% identity (55.2% similar) in 576 aa overlap (2-556:3-519) 10 20 30 40 50 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQN :: .:::.:::.: : .::.:::..:::::::::: :.:.:::::::::::::.:::. NP_005 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 RERQEQLMGYRKRGPKPK--PL-VVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQ .:....... :::: .:. : .. . . .:::.. :.. . .. . ....... NP_005 KEHEKEVQN-RKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSS 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 GHQYELNSKKHHQYQPHSKERAGKPPPPGKS----GKYYYQLNSKKHHPYQP-DPKMYDL . . : .: . :...: .: : :. .: . .:.. .: :.. NP_005 SDE-EDDSDLDAKRGPRGRET--HPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAT 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 QYQGGHKEAPSPTCPDLGAKSH--PPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGP . . .. . . :::: . :: : :: :.:.: : : : : : . NP_005 RRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAG----LAALK--AHAKEACGGPSAMAT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 PNGMMPAPKEAVTGNGIGG---KMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAE :... : ... : :: . .::. :. . .. . ::.. : : . NP_005 PENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATN-KCGLGLD 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 GEARSPSHKKRAADERHPPADRTFKK-AAGAEEKKVE---APPKRREEEVSGVSDPQPQD ..:. ... ::... : ..:: :.:: .::. . .. : :: NP_005 LKVRT----QKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB7 AGSRKLSPTKEAFGEQPLQLTTKPD--LLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHH : ...:: ... : .. . : ::: . . :. .: : . NP_005 APTQELS--LQVLDLQSVK-NGMPGVGLLARHATATKGVPATNPAPG------------K 350 360 370 380 390 410 420 430 440 450 460 pF1KB7 AVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAERPADLPPAAALPQP ..: .: . . .. : .:..:... :: ::..: : ..: :. NP_005 GTGSGLIGASGATMPTDTSKSE----KLASRAVAPPT-----PASKR--DCVKGSATPSG 400 410 420 430 470 480 490 500 510 pF1KB7 EVILLDSDLDEPIDLRCVKTRSE--AGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKP . . : . : . : : ::: :: . :.. :.: .:...: NP_005 Q-----ESRTAPGEARKAATLPEMSAGEESSSSDSDPDS-----------ASPPSTGQNP 440 450 460 470 480 520 530 540 550 560 pF1KB7 PAEAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV . .: ... . . .. ....:::::: .::: :: NP_005 SVSVQ--TSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY 490 500 510 520 530 >>XP_011523684 (OMIM: 602770,613080) PREDICTED: chromobo (586 aa) initn: 474 init1: 329 opt: 442 Z-score: 293.6 bits: 64.2 E(85289): 1.3e-09 Smith-Waterman score: 486; 27.4% identity (55.2% similar) in 576 aa overlap (2-556:3-519) 10 20 30 40 50 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQN :: .:::.:::.: : .::.:::..:::::::::: :.:.:::::::::::::.:::. XP_011 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 RERQEQLMGYRKRGPKPK--PL-VVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQ .:....... :::: .:. : .. . . .:::.. :.. . .. . ....... XP_011 KEHEKEVQN-RKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSS 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 GHQYELNSKKHHQYQPHSKERAGKPPPPGKS----GKYYYQLNSKKHHPYQP-DPKMYDL . . : .: . :...: .: : :. .: . .:.. .: :.. XP_011 SDE-EDDSDLDAKRGPRGRET--HPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAT 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 QYQGGHKEAPSPTCPDLGAKSH--PPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGP . . .. . . :::: . :: : :: :.:.: : : : : : . XP_011 RRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAG----LAALK--AHAKEACGGPSAMAT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 PNGMMPAPKEAVTGNGIGG---KMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAE :... : ... : :: . .::. :. . .. . ::.. : : . XP_011 PENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATN-KCGLGLD 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 GEARSPSHKKRAADERHPPADRTFKK-AAGAEEKKVE---APPKRREEEVSGVSDPQPQD ..:. ... ::... : ..:: :.:: .::. . .. : :: XP_011 LKVRT----QKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB7 AGSRKLSPTKEAFGEQPLQLTTKPD--LLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHH : ...:: ... : .. . : ::: . . :. .: : . XP_011 APTQELS--LQVLDLQSVK-NGMPGVGLLARHATATKGVPATNPAPG------------K 350 360 370 380 390 410 420 430 440 450 460 pF1KB7 AVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAERPADLPPAAALPQP ..: .: . . .. : .:..:... :: ::..: : ..: :. XP_011 GTGSGLIGASGATMPTDTSKSE----KLASRAVAPPT-----PASKR--DCVKGSATPSG 400 410 420 430 470 480 490 500 510 pF1KB7 EVILLDSDLDEPIDLRCVKTRSE--AGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKP . . : . : . : : ::: :: . :.. :.: .:...: XP_011 Q-----ESRTAPGEARKAATLPEMSAGEESSSSDSDPDS-----------ASPPSTGQNP 440 450 460 470 480 520 530 540 550 560 pF1KB7 PAEAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV . .: ... . . .. ....:::::: .::: :: XP_011 SVSVQ--TSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRPLCSPLLPQET 490 500 510 520 530 540 XP_011 RWHLWLQVTVLNRAGFFMAALLLSLNCSSLACVTESQLWSLSCRG 550 560 570 580 >>XP_006724240 (OMIM: 608457) PREDICTED: chromobox prote (192 aa) initn: 505 init1: 426 opt: 427 Z-score: 291.0 bits: 62.1 E(85289): 1.8e-09 Smith-Waterman score: 427; 66.3% identity (91.0% similar) in 89 aa overlap (1-89:1-88) 10 20 30 40 50 60 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR ::: :.::.:::::::.:::.:::.:::::::.:: :::.::::::.::::::..:.... XP_006 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY :.... :::::::::: :..: : :.. XP_006 EERDRASGYRKRGPKPKRLLLQ-PRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPP 70 80 90 100 110 >>XP_011528327 (OMIM: 608457) PREDICTED: chromobox prote (165 aa) initn: 495 init1: 333 opt: 407 Z-score: 279.5 bits: 59.8 E(85289): 7.9e-09 Smith-Waterman score: 407; 63.0% identity (84.8% similar) in 92 aa overlap (1-84:1-92) 10 20 30 40 50 60 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR ::: :.::.:::::::.:::.:::.:::::::.:: :::.::::::.::::::..:.... XP_011 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 --------ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQ :.... :::::::::: :..: : XP_011 YGVLGTAGEERDRASGYRKRGPKPKRLLLQEPPAPDVLQAAGEWEPAAQPPEEEDADLAE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 GKGQGHQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQ XP_011 GPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF 130 140 150 160 >>XP_006724241 (OMIM: 608457) PREDICTED: chromobox prote (166 aa) initn: 466 init1: 333 opt: 407 Z-score: 279.4 bits: 59.8 E(85289): 7.9e-09 Smith-Waterman score: 407; 63.0% identity (84.8% similar) in 92 aa overlap (1-84:1-92) 10 20 30 40 50 60 pF1KB7 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR ::: :.::.:::::::.:::.:::.:::::::.:: :::.::::::.::::::..:.... XP_006 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 --------ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQ :.... :::::::::: :..: : XP_006 YGVLGTAGEERDRASGYRKRGPKPKRLLLQEPPAPDVLQAAGEWEPAAQPPEEEADADLA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 GKGQGHQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQ XP_006 EGPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF 130 140 150 160 560 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:11:50 2016 done: Fri Nov 4 21:11:52 2016 Total Scan time: 12.090 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]