Result of FASTA (omim) for
pF1KB7868
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7868, 634 aa
1>>>pF1KB7868 634 - 634 aa - 634 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7151+/-0.000368; mu= 2.3742+/- 0.023
mean_var=514.7222+/-127.915, 0's: 0 Z-trim(124.6): 642 B-trim: 2684 in 1/53
Lambda= 0.056531
statistics sampled from 45067 (46599) to 45067 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.546), width: 16
Scan time: 12.150
The best scores are: opt bits E(85289)
NP_001138810 (OMIM: 611439) zinc finger and BTB do ( 634) 4348 369.6 1.8e-101
NP_005444 (OMIM: 611439) zinc finger and BTB domai ( 634) 4348 369.6 1.8e-101
NP_001092740 (OMIM: 611692) zinc finger and BTB do ( 500) 450 51.6 8.1e-06
XP_011517001 (OMIM: 611692) PREDICTED: zinc finger ( 504) 450 51.6 8.2e-06
XP_005252046 (OMIM: 611692) PREDICTED: zinc finger ( 514) 450 51.6 8.3e-06
XP_005260859 (OMIM: 613842) PREDICTED: GDNF-induci ( 545) 347 43.2 0.0029
XP_016883508 (OMIM: 613842) PREDICTED: GDNF-induci ( 545) 347 43.2 0.0029
XP_005259778 (OMIM: 610672) PREDICTED: nucleus acc ( 527) 344 43.0 0.0034
NP_443108 (OMIM: 610672) nucleus accumbens-associa ( 527) 344 43.0 0.0034
XP_011514140 (OMIM: 613914) PREDICTED: zinc finger ( 632) 338 42.6 0.0052
NP_689770 (OMIM: 613914) zinc finger protein 746 i ( 644) 338 42.6 0.0053
NP_001156946 (OMIM: 613914) zinc finger protein 74 ( 645) 338 42.6 0.0053
XP_005250014 (OMIM: 613914) PREDICTED: zinc finger ( 647) 338 42.6 0.0053
XP_005250013 (OMIM: 613914) PREDICTED: zinc finger ( 659) 338 42.6 0.0053
XP_005250012 (OMIM: 613914) PREDICTED: zinc finger ( 660) 338 42.6 0.0053
>>NP_001138810 (OMIM: 611439) zinc finger and BTB domain (634 aa)
initn: 4348 init1: 4348 opt: 4348 Z-score: 1942.5 bits: 369.6 E(85289): 1.8e-101
Smith-Waterman score: 4348; 99.8% identity (100.0% similar) in 634 aa overlap (1-634:1-634)
10 20 30 40 50 60
pF1KB7 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KRGGNCPAPAPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG
550 560 570 580 590 600
610 620 630
pF1KB7 DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
::::::::::::::::::::::::::::::::::
NP_001 DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
610 620 630
>>NP_005444 (OMIM: 611439) zinc finger and BTB domain-co (634 aa)
initn: 4348 init1: 4348 opt: 4348 Z-score: 1942.5 bits: 369.6 E(85289): 1.8e-101
Smith-Waterman score: 4348; 99.8% identity (100.0% similar) in 634 aa overlap (1-634:1-634)
10 20 30 40 50 60
pF1KB7 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KRGGNCPAPAPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG
550 560 570 580 590 600
610 620 630
pF1KB7 DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
::::::::::::::::::::::::::::::::::
NP_005 DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
610 620 630
>>NP_001092740 (OMIM: 611692) zinc finger and BTB domain (500 aa)
initn: 628 init1: 411 opt: 450 Z-score: 225.4 bits: 51.6 E(85289): 8.1e-06
Smith-Waterman score: 551; 26.8% identity (52.5% similar) in 541 aa overlap (26-559:1-446)
10 20 30 40 50 60
pF1KB7 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
. ... .. . :: .:..: .::. ::::.:::.
NP_001 MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDII
10 20 30
70 80 90 100 110 120
pF1KB7 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
...::. ::::.::::::::::.:. :. :...:. . .:..:: .:. ::::.:.
NP_001 VHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
:.:.:::..: ::: ..::::..:. : . :... . :::: . : . .:.
NP_001 LKDVVSFLTAASFLQMQCVIDKCTQILE----SIHSKISVGDVDSVTVGAEENPESRNGV
100 110 120 130 140 150
190 200 210 220 230
pF1KB7 VAPATMGSARSHASSRASENQSPSSSN--YFSPRESTDFSSSSQEAFAASAVGSGERRGG
. ... . :....:..:. . : . : :: : ..: ..
NP_001 KDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEE------GHSDRGSS
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 GPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWV
: : . : .: ::.. ... . . : ::.
NP_001 GSVSEYEIQIEGDHEQGDLLVRESQITE-------VKVKMEKSDRPS-------------
210 220 230 240
300 310 320 330 340 350
pF1KB7 YVKRGGNCPAPAPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGG-GPEATLS
: . : : . : . . :.. : ::. : .
NP_001 -------CSDSSSL--GDDGYHTEMVDGEQVVA--------------VNVGSYGSVLQHA
250 260 270 280
360 370 380 390 400 410
pF1KB7 ISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDS--GGPTPSSYAPS-HPPR
: .. :.: . .: :: ...: .. . :: . .. : : :
NP_001 YSYSQAASQPTNVSEA----------FGSLSNSSPSRSMLSCFRGGRARQKRALSVH---
290 300 310 320
420 430 440 450 460 470
pF1KB7 PLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVP
: :.:: :: ..:.:.: . :: .. .. : :
NP_001 --LHSDLQG---LV-----QGSDSEAMMNNPGYESSPRERSARGH------------WYP
330 340 350 360
480 490 500 510 520 530
pF1KB7 GGTGSGDGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMK
:. ..: .:::.:..:. :::. .:... :: : :.::. : .: :..
NP_001 Y-------NERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIR
370 380 390 400 410 420
540 550 560 570 580 590
pF1KB7 THTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESP
:: ::..: .:.: : .. .. .:
NP_001 GHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDAS
430 440 450 460 470 480
>>XP_011517001 (OMIM: 611692) PREDICTED: zinc finger and (504 aa)
initn: 628 init1: 411 opt: 450 Z-score: 225.4 bits: 51.6 E(85289): 8.2e-06
Smith-Waterman score: 551; 26.8% identity (52.5% similar) in 541 aa overlap (26-559:5-450)
10 20 30 40 50 60
pF1KB7 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
. ... .. . :: .:..: .::. ::::.:::.
XP_011 MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDII
10 20 30
70 80 90 100 110 120
pF1KB7 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
...::. ::::.::::::::::.:. :. :...:. . .:..:: .:. ::::.:.
XP_011 VHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
:.:.:::..: ::: ..::::..:. : . :... . :::: . : . .:.
XP_011 LKDVVSFLTAASFLQMQCVIDKCTQILE----SIHSKISVGDVDSVTVGAEENPESRNGV
100 110 120 130 140 150
190 200 210 220 230
pF1KB7 VAPATMGSARSHASSRASENQSPSSSN--YFSPRESTDFSSSSQEAFAASAVGSGERRGG
. ... . :....:..:. . : . : :: : ..: ..
XP_011 KDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEE------GHSDRGSS
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 GPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWV
: : . : .: ::.. ... . . : ::.
XP_011 GSVSEYEIQIEGDHEQGDLLVRESQITE-------VKVKMEKSDRPS-------------
210 220 230 240
300 310 320 330 340 350
pF1KB7 YVKRGGNCPAPAPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGG-GPEATLS
: . : : . : . . :.. : ::. : .
XP_011 -------CSDSSSL--GDDGYHTEMVDGEQVVA--------------VNVGSYGSVLQHA
250 260 270 280
360 370 380 390 400 410
pF1KB7 ISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDS--GGPTPSSYAPS-HPPR
: .. :.: . .: :: ...: .. . :: . .. : : :
XP_011 YSYSQAASQPTNVSEA----------FGSLSNSSPSRSMLSCFRGGRARQKRALSVH---
290 300 310 320 330
420 430 440 450 460 470
pF1KB7 PLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVP
: :.:: :: ..:.:.: . :: .. .. : :
XP_011 --LHSDLQG---LV-----QGSDSEAMMNNPGYESSPRERSARGH------------WYP
340 350 360 370
480 490 500 510 520 530
pF1KB7 GGTGSGDGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMK
:. ..: .:::.:..:. :::. .:... :: : :.::. : .: :..
XP_011 Y-------NERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIR
380 390 400 410 420
540 550 560 570 580 590
pF1KB7 THTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESP
:: ::..: .:.: : .. .. .:
XP_011 GHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDAS
430 440 450 460 470 480
>>XP_005252046 (OMIM: 611692) PREDICTED: zinc finger and (514 aa)
initn: 628 init1: 411 opt: 450 Z-score: 225.3 bits: 51.6 E(85289): 8.3e-06
Smith-Waterman score: 551; 26.8% identity (52.5% similar) in 541 aa overlap (26-559:15-460)
10 20 30 40 50 60
pF1KB7 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
. ... .. . :: .:..: .::. ::::.:::.
XP_005 MEECKSRVRFMSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDII
10 20 30 40
70 80 90 100 110 120
pF1KB7 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
...::. ::::.::::::::::.:. :. :...:. . .:..:: .:. ::::.:.
XP_005 VHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
:.:.:::..: ::: ..::::..:. : . :... . :::: . : . .:.
XP_005 LKDVVSFLTAASFLQMQCVIDKCTQILE----SIHSKISVGDVDSVTVGAEENPESRNGV
110 120 130 140 150 160
190 200 210 220 230
pF1KB7 VAPATMGSARSHASSRASENQSPSSSN--YFSPRESTDFSSSSQEAFAASAVGSGERRGG
. ... . :....:..:. . : . : :: : ..: ..
XP_005 KDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEE------GHSDRGSS
170 180 190 200 210
240 250 260 270 280 290
pF1KB7 GPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWV
: : . : .: ::.. ... . . : ::.
XP_005 GSVSEYEIQIEGDHEQGDLLVRESQITE-------VKVKMEKSDRPS-------------
220 230 240 250
300 310 320 330 340 350
pF1KB7 YVKRGGNCPAPAPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGG-GPEATLS
: . : : . : . . :.. : ::. : .
XP_005 -------CSDSSSL--GDDGYHTEMVDGEQVVA--------------VNVGSYGSVLQHA
260 270 280 290
360 370 380 390 400 410
pF1KB7 ISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDS--GGPTPSSYAPS-HPPR
: .. :.: . .: :: ...: .. . :: . .. : : :
XP_005 YSYSQAASQPTNVSEA----------FGSLSNSSPSRSMLSCFRGGRARQKRALSVH---
300 310 320 330 340
420 430 440 450 460 470
pF1KB7 PLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVP
: :.:: :: ..:.:.: . :: .. .. : :
XP_005 --LHSDLQG---LV-----QGSDSEAMMNNPGYESSPRERSARGH------------WYP
350 360 370 380
480 490 500 510 520 530
pF1KB7 GGTGSGDGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMK
:. ..: .:::.:..:. :::. .:... :: : :.::. : .: :..
XP_005 Y-------NERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIR
390 400 410 420 430
540 550 560 570 580 590
pF1KB7 THTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESP
:: ::..: .:.: : .. .. .:
XP_005 GHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDAS
440 450 460 470 480 490
>>XP_005260859 (OMIM: 613842) PREDICTED: GDNF-inducible (545 aa)
initn: 744 init1: 216 opt: 347 Z-score: 179.6 bits: 43.2 E(85289): 0.0029
Smith-Waterman score: 347; 24.2% identity (50.7% similar) in 558 aa overlap (43-566:17-545)
20 30 40 50 60
pF1KB7 LPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRV--QG--REF
::. ... :: :.::::.. : :: ..:
XP_005 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDF
10 20 30 40
70 80 90 100 110 120
pF1KB7 RAHRAVLAASSPYFHDQVL----LKGM-TSISLPSVMDPGAFETVLASAYTGRLSMAAAD
::.:::::.: .:.. : . : :.. : :. . : . : .::.....
XP_005 MAHKAVLAATSKFFKEVFLNEKSVDGTRTNVYLNEVQ-VADFASFLEFVYTAKVQVEEDR
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 IVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAP
. .: :. :. . . : .: .. :. . . . .. . : ::: ..::
XP_005 VQRMLEVAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEVE----VSSGSQVSAAP
110 120 130 140 150 160
190 200 210 220 230
pF1KB7 ATMGSARSHASSRASENQSPS----SSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGG
: .:. :... :: : .: . : :. .::. . . . . ...
XP_005 APRASV-------ATDGPHPSGLTDSLDYPGERASNGMSSDLPPKKSKDKLDK-KKEVVK
170 180 190 200 210
240 250 260 270 280 290
pF1KB7 PVFPAPVVGSGGATSGKLLLEADE------LCDDGGDGRGAVVPGAGLRRPT-YTPPSIM
: .: .:: .. :...: . : .. ..: : . : : .: .
XP_005 PPYPKIRRASGRLAGRKVFVEIPKKKYTRRLREQQKTAEGDV---GDYRCPQDQSPDRVG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB7 PQKHWVYVKRGGNCPAPAPL--VPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGG
. . : ..: : : : : . . :::::::. ::.: :. .. . .
XP_005 TEMEQVSKNEG--CQAGAELEELSKKAGPEEEEEEEE-----EDEEGEKKKSNFKCSIC-
280 290 300 310 320
360 370 380 390 400
pF1KB7 GPEATL-SISDVRTLSEPPDKGEEQVNFCESSND-FGPYEG-GGPVAGLDDSGGPTPSSY
.: : : .. .. . : : :.. .. :. . . . .: :
XP_005 -EKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCEL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KB7 APSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAE---HGAVTVGGTSVGSL
.. : :.. . . : ... :. .... : . .: :
XP_005 CGKKFKRK---KDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDRPYGCT
390 400 410 420 430
470 480 490 500 510
pF1KB7 GVPGSVGGVPGGTGSG----DGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCN
:. . :.. . :.: :.: .:: :... : : : . ::: : .:.
XP_005 EC-GARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCG
440 450 460 470 480 490
520 530 540 550 560 570
pF1KB7 KKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH-RGHCERRHRLGGVGAVPGP
:.: :..: .: . ::: ::..: :: . : :.:...: . : . :
XP_005 KSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTDTR
500 510 520 530 540
580 590 600 610 620 630
pF1KB7 GTPTGPSLPSKRESPGVGGGSGDEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
>>XP_016883508 (OMIM: 613842) PREDICTED: GDNF-inducible (545 aa)
initn: 744 init1: 216 opt: 347 Z-score: 179.6 bits: 43.2 E(85289): 0.0029
Smith-Waterman score: 347; 24.2% identity (50.7% similar) in 558 aa overlap (43-566:17-545)
20 30 40 50 60
pF1KB7 LPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRV--QG--REF
::. ... :: :.::::.. : :: ..:
XP_016 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDF
10 20 30 40
70 80 90 100 110 120
pF1KB7 RAHRAVLAASSPYFHDQVL----LKGM-TSISLPSVMDPGAFETVLASAYTGRLSMAAAD
::.:::::.: .:.. : . : :.. : :. . : . : .::.....
XP_016 MAHKAVLAATSKFFKEVFLNEKSVDGTRTNVYLNEVQ-VADFASFLEFVYTAKVQVEEDR
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 IVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAP
. .: :. :. . . : .: .. :. . . . .. . : ::: ..::
XP_016 VQRMLEVAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEVE----VSSGSQVSAAP
110 120 130 140 150 160
190 200 210 220 230
pF1KB7 ATMGSARSHASSRASENQSPS----SSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGG
: .:. :... :: : .: . : :. .::. . . . . ...
XP_016 APRASV-------ATDGPHPSGLTDSLDYPGERASNGMSSDLPPKKSKDKLDK-KKEVVK
170 180 190 200 210
240 250 260 270 280 290
pF1KB7 PVFPAPVVGSGGATSGKLLLEADE------LCDDGGDGRGAVVPGAGLRRPT-YTPPSIM
: .: .:: .. :...: . : .. ..: : . : : .: .
XP_016 PPYPKIRRASGRLAGRKVFVEIPKKKYTRRLREQQKTAEGDV---GDYRCPQDQSPDRVG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB7 PQKHWVYVKRGGNCPAPAPL--VPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGG
. . : ..: : : : : . . :::::::. ::.: :. .. . .
XP_016 TEMEQVSKNEG--CQAGAELEELSKKAGPEEEEEEEE-----EDEEGEKKKSNFKCSIC-
280 290 300 310 320
360 370 380 390 400
pF1KB7 GPEATL-SISDVRTLSEPPDKGEEQVNFCESSND-FGPYEG-GGPVAGLDDSGGPTPSSY
.: : : .. .. . : : :.. .. :. . . . .: :
XP_016 -EKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCEL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KB7 APSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAE---HGAVTVGGTSVGSL
.. : :.. . . : ... :. .... : . .: :
XP_016 CGKKFKRK---KDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDRPYGCT
390 400 410 420 430
470 480 490 500 510
pF1KB7 GVPGSVGGVPGGTGSG----DGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCN
:. . :.. . :.: :.: .:: :... : : : . ::: : .:.
XP_016 EC-GARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCG
440 450 460 470 480 490
520 530 540 550 560 570
pF1KB7 KKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH-RGHCERRHRLGGVGAVPGP
:.: :..: .: . ::: ::..: :: . : :.:...: . : . :
XP_016 KSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTDTR
500 510 520 530 540
580 590 600 610 620 630
pF1KB7 GTPTGPSLPSKRESPGVGGGSGDEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
>>XP_005259778 (OMIM: 610672) PREDICTED: nucleus accumbe (527 aa)
initn: 380 init1: 300 opt: 344 Z-score: 178.5 bits: 43.0 E(85289): 0.0034
Smith-Waterman score: 344; 34.4% identity (63.6% similar) in 209 aa overlap (29-236:2-202)
10 20 30 40 50 60
pF1KB7 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
: .... .:. ...:: ::.::::: ::::
XP_005 MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVS
10 20 30
70 80 90 100 110 120
pF1KB7 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
. :.:. :.:::::::::: ::.: . . . ::....: .:. .:. :::::::
XP_005 VVVKGHAFKAHRAVLAASSSYFRDLFNNSRSAVVELPAAVQPQSFQQILSFCYTGRLSMN
40 50 60 70 80 90
130 140 150 160 170
pF1KB7 AADIVNFLTVGSVLQMWHIVDKCTEL-LREGRASATTTITTAAATSVTVPGAGVPSGSGG
..: .. ... ::. .:..: ::. :. . : . : . . : . : . ::
XP_005 VGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHAEEAPSSEPQSPVAQTSGW
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 TVAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGG
:: :. ::.. .:. :.: : . ..:...: :.. :.: :.
XP_005 ---PAC--STPLPLVSRVKTEQQESDSVQCMPVAKRLWDSGQKE---AGGGGNGSRKMAK
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 PVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVY
XP_005 FSTPDLAANRPHQPPPPQQAPVVAAAQPAVAAGAGQPAGGVAAAGGVVSGPSTSERTSPG
210 220 230 240 250 260
>>NP_443108 (OMIM: 610672) nucleus accumbens-associated (527 aa)
initn: 380 init1: 300 opt: 344 Z-score: 178.5 bits: 43.0 E(85289): 0.0034
Smith-Waterman score: 344; 34.4% identity (63.6% similar) in 209 aa overlap (29-236:2-202)
10 20 30 40 50 60
pF1KB7 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
: .... .:. ...:: ::.::::: ::::
NP_443 MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVS
10 20 30
70 80 90 100 110 120
pF1KB7 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
. :.:. :.:::::::::: ::.: . . . ::....: .:. .:. :::::::
NP_443 VVVKGHAFKAHRAVLAASSSYFRDLFNNSRSAVVELPAAVQPQSFQQILSFCYTGRLSMN
40 50 60 70 80 90
130 140 150 160 170
pF1KB7 AADIVNFLTVGSVLQMWHIVDKCTEL-LREGRASATTTITTAAATSVTVPGAGVPSGSGG
..: .. ... ::. .:..: ::. :. . : . : . . : . : . ::
NP_443 VGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHAEEAPSSEPQSPVAQTSGW
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 TVAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGG
:: :. ::.. .:. :.: : . ..:...: :.. :.: :.
NP_443 ---PAC--STPLPLVSRVKTEQQESDSVQCMPVAKRLWDSGQKE---AGGGGNGSRKMAK
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 PVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVY
NP_443 FSTPDLAANRPHQPPPPQQAPVVAAAQPAVAAGAGQPAGGVAAAGGVVSGPSTSERTSPG
210 220 230 240 250 260
>>XP_011514140 (OMIM: 613914) PREDICTED: zinc finger pro (632 aa)
initn: 402 init1: 270 opt: 338 Z-score: 175.0 bits: 42.6 E(85289): 0.0052
Smith-Waterman score: 371; 27.4% identity (49.4% similar) in 340 aa overlap (277-597:301-606)
250 260 270 280 290 300
pF1KB7 VGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNC
:: . : . : : .. .. ..:..
XP_011 IVIKTEVQEEEVVATPVHPTDLEAHGTLFGPGQATR---FFPS---PAQEGAWESQGSSF
280 290 300 310 320
310 320 330 340 350
pF1KB7 PAPAPLV----PQDPDLEEEEEEEDLVLTCEDDEDEELGG-------SSRVPVG----GG
:. :.. : :. . : .. : .:: . ::: :
XP_011 PSQDPVLGLREPARPERDMGELSPAVAQEETPPGDWLFGGVRWGWNFRCKPPVGLNPRTG
330 340 350 360 370 380
360 370 380 390 400 410
pF1KB7 PEATLSISDVRTLSEPPDKGEEQVNFCESSNDFG-PYEGGGPVAGLDDSGGPTPSSYAPS
::. : :. ::.:: .. .. :. : . : . :. . : . :.
XP_011 PEG-LPYSS-------PDNGEAILDPSQAPRPFNEPCKYPGRTKGFGHKPG---LKKHPA
390 400 410 420 430
420 430 440 450 460
pF1KB7 HPP--RPLLPLDMQGNQILVFPSSSSSSSSQAP-GQPPGNQAEHGAVTVGGTSVGSLGVP
:: ::. . : :. . : :: :. ::. :: . ::
XP_011 APPGGRPFTCATCGKSFQLQVSLSAHQRSCGAPDGSGPGT---------GGGGSGS----
440 450 460 470 480
470 480 490 500 510 520
pF1KB7 GSVGGVPGGTGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHH
:. :: :: .. ::. . .::. :.. . :: .: . ::: : :.:.: . .
XP_011 GGGGGGSGGGSARDGSALRCGECGRCFTRPAHLIRHRMLHTGERPFPCTECEKRFTERSK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB7 LTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLP
: .:..::::..:. : ::.:.:. .: . .: .: : :. . : :: :. :
XP_011 LIDHYRTHTGVRPFTCTVCGKSFIRKDHLRKH----QRNHAAGAKTPARGQPLPTPPAPP
550 560 570 580 590
590 600 610 620 630
pF1KB7 SKRESPGVGGGSGDEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
. .::. :
XP_011 DPFKSPASKGPLASTDLVTDWTCGLSVLGPTDGGDM
600 610 620 630
634 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:12:21 2016 done: Fri Nov 4 21:12:23 2016
Total Scan time: 12.150 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]