FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7885, 581 aa 1>>>pF1KB7885 581 - 581 aa - 581 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7067+/-0.000386; mu= 18.6162+/- 0.024 mean_var=101.5038+/-20.238, 0's: 0 Z-trim(114.6): 7 B-trim: 310 in 1/53 Lambda= 0.127301 statistics sampled from 24575 (24578) to 24575 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.288), width: 16 Scan time: 11.060 The best scores are: opt bits E(85289) NP_057297 (OMIM: 604501,616866,617066) activating ( 581) 3922 731.2 2.2e-210 NP_001308853 (OMIM: 604501,616866,617066) activati ( 351) 2365 445.1 1.8e-124 >>NP_057297 (OMIM: 604501,616866,617066) activating sign (581 aa) initn: 3922 init1: 3922 opt: 3922 Z-score: 3898.0 bits: 731.2 E(85289): 2.2e-210 Smith-Waterman score: 3922; 100.0% identity (100.0% similar) in 581 aa overlap (1-581:1-581) 10 20 30 40 50 60 pF1KB7 MAVAGAVSGEPLVHWCTQQLRKTFGLDVSEEIIQYVLSIESAEEIREYVTDLLQGNEGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MAVAGAVSGEPLVHWCTQQLRKTFGLDVSEEIIQYVLSIESAEEIREYVTDLLQGNEGKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PDTTAEVKTPFDLAKAQENSNSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PDTTAEVKTPFDLAKAQENSNSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDCLGQKHKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 INNCLICGRIVCEQEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 INNCLICGRIVCEQEGSGPCLFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 DISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 DISTKDLLPHQELRIKSGLEKAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LERETLQKREEELRELRHASRLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LNQPLTKLDRSSEEPLGVLVNPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 RIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 RIQDQEFQEGFDGGWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 VSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFI 490 500 510 520 530 540 550 560 570 580 pF1KB7 CKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV ::::::::::::::::::::::::::::::::::::::::: NP_057 CKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV 550 560 570 580 >>NP_001308853 (OMIM: 604501,616866,617066) activating s (351 aa) initn: 2365 init1: 2365 opt: 2365 Z-score: 2355.4 bits: 445.1 E(85289): 1.8e-124 Smith-Waterman score: 2365; 100.0% identity (100.0% similar) in 351 aa overlap (231-581:1-351) 210 220 230 240 250 260 pF1KB7 LFCGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENSGKVDISTKDLLPHQELRIKSGLE :::::::::::::::::::::::::::::: NP_001 MSGVENSGKVDISTKDLLPHQELRIKSGLE 10 20 30 270 280 290 300 310 320 pF1KB7 KAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAIKHKDKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKLERETLQKREEELRELRHAS 40 50 60 70 80 90 330 340 350 360 370 380 pF1KB7 RLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSEEPLGVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLSKKVTIDFAGRKILEEENSLAEYHSRLDETIQAIANGTLNQPLTKLDRSSEEPLGVLV 100 110 120 130 140 150 390 400 410 420 430 440 pF1KB7 NPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQLRIQDQEFQEGFDGGWCLSVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPNMYQSPPQWVDHTGAASQKKAFRSSGFGLEFNSFQHQLRIQDQEFQEGFDGGWCLSVH 160 170 180 190 200 210 450 460 470 480 490 500 pF1KB7 QPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQEVSELQATYRLLRGKDVEFPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQEVSELQATYRLLRGKDVEFPN 220 230 240 250 260 270 510 520 530 540 550 560 pF1KB7 DYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYPSGCLLGCVDLIDCLSQKQFKEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIW 280 290 300 310 320 330 570 580 pF1KB7 KLDSKIHQGAKKGLMKQNKAV ::::::::::::::::::::: NP_001 KLDSKIHQGAKKGLMKQNKAV 340 350 581 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:15:55 2016 done: Fri Nov 4 21:15:56 2016 Total Scan time: 11.060 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]