FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7888, 651 aa 1>>>pF1KB7888 651 - 651 aa - 651 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6638+/-0.000383; mu= 18.6786+/- 0.024 mean_var=88.1020+/-17.947, 0's: 0 Z-trim(113.9): 27 B-trim: 259 in 1/53 Lambda= 0.136641 statistics sampled from 23485 (23492) to 23485 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.275), width: 16 Scan time: 11.210 The best scores are: opt bits E(85289) NP_004259 (OMIM: 603810,613668) mediator of RNA po ( 651) 4307 859.5 0 XP_011541370 (OMIM: 603810,613668) PREDICTED: medi ( 652) 3469 694.3 3.5e-199 >>NP_004259 (OMIM: 603810,613668) mediator of RNA polyme (651 aa) initn: 4307 init1: 4307 opt: 4307 Z-score: 4589.7 bits: 859.5 E(85289): 0 Smith-Waterman score: 4307; 100.0% identity (100.0% similar) in 651 aa overlap (1-651:1-651) 10 20 30 40 50 60 pF1KB7 MSGVRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSGVRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 CPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 VLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 LQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 SQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQMSQHQVHAVQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQMSQHQVHAVQQL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 AKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQ 550 560 570 580 590 600 610 620 630 640 650 pF1KB7 CKDLPKSDVLQDNKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CKDLPKSDVLQDNKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL 610 620 630 640 650 >>XP_011541370 (OMIM: 603810,613668) PREDICTED: mediator (652 aa) initn: 3469 init1: 3469 opt: 3469 Z-score: 3696.9 bits: 694.3 E(85289): 3.5e-199 Smith-Waterman score: 3469; 100.0% identity (100.0% similar) in 528 aa overlap (1-528:1-528) 10 20 30 40 50 60 pF1KB7 MSGVRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSGVRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 CPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 VLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 LQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 SQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQMSQHQVHAVQQL :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQFVMDLKVAARLW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 AKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQ XP_011 FSFLVTNVKTFQKVMFYKITNGVIFVGHSKKFSGIKWKVEILFIKWSCLCLHLALVYYDF 550 560 570 580 590 600 651 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:17:17 2016 done: Fri Nov 4 21:17:18 2016 Total Scan time: 11.210 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]