FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7890, 652 aa 1>>>pF1KB7890 652 - 652 aa - 652 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1034+/-0.000987; mu= 12.7616+/- 0.060 mean_var=162.5744+/-31.682, 0's: 0 Z-trim(109.6): 64 B-trim: 0 in 0/55 Lambda= 0.100588 statistics sampled from 10938 (10999) to 10938 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.338), width: 16 Scan time: 3.860 The best scores are: opt bits E(32554) CCDS54007.1 BRD7 gene_id:29117|Hs108|chr16 ( 652) 4325 640.2 2.6e-183 CCDS10742.1 BRD7 gene_id:29117|Hs108|chr16 ( 651) 4306 637.4 1.8e-182 CCDS34127.2 BRD9 gene_id:65980|Hs108|chr5 ( 597) 875 139.5 1.3e-32 CCDS34128.2 BRD9 gene_id:65980|Hs108|chr5 ( 544) 427 74.5 4.5e-13 >>CCDS54007.1 BRD7 gene_id:29117|Hs108|chr16 (652 aa) initn: 4325 init1: 4325 opt: 4325 Z-score: 3404.4 bits: 640.2 E(32554): 2.6e-183 Smith-Waterman score: 4325; 100.0% identity (100.0% similar) in 652 aa overlap (1-652:1-652) 10 20 30 40 50 60 pF1KB7 MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 MLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLGLLHPVDPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLGLLHPVDPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 VGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFAN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 ISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGHSRTLQEME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGHSRTLQEME 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MSLPEDEGHTRTLDTAKEMEQITEVEPPGRLDSSTQDRLIALKAVTNFGVPVEVFDSEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MSLPEDEGHTRTLDTAKEMEQITEVEPPGRLDSSTQDRLIALKAVTNFGVPVEVFDSEEA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 EIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMHLAEQVTNNLKELAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMHLAEQVTNNLKELAQQ 550 560 570 580 590 600 610 620 630 640 650 pF1KB7 VTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVAECGPGGS :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVAECGPGGS 610 620 630 640 650 >>CCDS10742.1 BRD7 gene_id:29117|Hs108|chr16 (651 aa) initn: 3336 init1: 3336 opt: 4306 Z-score: 3389.5 bits: 637.4 E(32554): 1.8e-182 Smith-Waterman score: 4306; 99.8% identity (99.8% similar) in 652 aa overlap (1-652:1-651) 10 20 30 40 50 60 pF1KB7 MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 MLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLGLLHPVDPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLGLLHPVDPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 VGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFAN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 ISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGHSRTLQEME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGHSRTLQEME 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MSLPEDEGHTRTLDTAKEMEQITEVEPPGRLDSSTQDRLIALKAVTNFGVPVEVFDSEEA :::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: CCDS10 MSLPEDEGHTRTLDTAKEME-ITEVEPPGRLDSSTQDRLIALKAVTNFGVPVEVFDSEEA 490 500 510 520 530 550 560 570 580 590 600 pF1KB7 EIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMHLAEQVTNNLKELAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMHLAEQVTNNLKELAQQ 540 550 560 570 580 590 610 620 630 640 650 pF1KB7 VTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVAECGPGGS :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVAECGPGGS 600 610 620 630 640 650 >>CCDS34127.2 BRD9 gene_id:65980|Hs108|chr5 (597 aa) initn: 1033 init1: 715 opt: 875 Z-score: 699.1 bits: 139.5 E(32554): 1.3e-32 Smith-Waterman score: 1171; 36.0% identity (68.0% similar) in 600 aa overlap (1-585:1-562) 10 20 30 40 50 pF1KB7 MGKKHKKHKSD-KHLYEEY----VEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDH :::::::::.. . ::.: .::::::::::::.:::::: .:::::: ..:..:: CCDS34 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELS--GSGHDSSYYDDRSDH 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 DK--HKDRKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKD-LQCHAPVR .. ::..:.::.::.::. ... :..:. .: :.::.:.. ..:.: : .. :. CCDS34 ERERHKEKKKKKKKKSEKEKHLDDEERRKRK-EEKKRKREREHCDTEGEADDFDPGKKVE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 LDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMII .. ::..:. . .. : :.::.:. :....:::::::: .::.::::: ::::::::: CCDS34 VEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 KHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKIL ::::::.:::.:: :.:.:. :.: .::::: ::: ::.:.:.::: :::.::.:.:.. CCDS34 KHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 SQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSK :.. .: . : .. . ..:.. . .. : .. . :. .. CCDS34 SKQ--AALLGNEDTAVEEPVPEVVPVQVETAK---------KSKKPSREVISCMFEPEGN 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 ENKKKDKDMLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLG . : :. :. ... . :. ...: : ... . .:. ::. . CCDS34 ACSLTD---------STAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYS 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 LLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAP ... ..: . : :: :. ...: : .:: :::...::::: .:. . .. . CCDS34 VVNTAEPDADEEETHPVDLSSLSSKLLPGFTTL-GFKDERRNKVT---FLS-SATTALSM 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB7 HYDSTFANISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGH . .:.:.....:. .:.::.::... . .:..::. .: ..:.::: .: : : CCDS34 QNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDH 400 410 420 430 440 450 480 490 500 510 520 pF1KB7 SRTLQEMEMSL-----PEDEGHT-RTL-DTAKEMEQITEVEPPGRLDSSTQDRLIALKAV :::: .... : ::... :: :... . .. .. : : . .. . CCDS34 SRTLFQLKQRRNVPMKPPDEAKVGDTLGDSSSSVLEFMSMK-------SYPDVSVDISML 460 470 480 490 500 530 540 550 560 570 580 pF1KB7 TNFGVPVEVFDSEEAEIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMH ...: . .: ..... .:::::.::..:.::: :: ..:: :. : . : :..: CCDS34 SSLGKVKKELDPDDSHL---NLDETTKLLQDLHEAQAERGGSRPSSNLSSLSNASERDQH 510 520 530 540 550 560 590 600 610 620 630 640 pF1KB7 LAEQVTNNLKELAQQVTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVA CCDS34 HLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT 570 580 590 >>CCDS34128.2 BRD9 gene_id:65980|Hs108|chr5 (544 aa) initn: 717 init1: 422 opt: 427 Z-score: 348.2 bits: 74.5 E(32554): 4.5e-13 Smith-Waterman score: 723; 29.0% identity (61.0% similar) in 534 aa overlap (59-585:13-509) 30 40 50 60 70 80 pF1KB7 VGGNEVTELSTGSSGHDSSLFEDKNDHDKHKDRKRKKRKKGEKQIPGEEKGRKRRRVKED : :::..:.. ... . . .: ... CCDS34 MMTGQTMSERGTKKRKRRRRRSPRRRSIWTMRKEGSERKRRS 10 20 30 40 90 100 110 120 130 140 pF1KB7 KKKRDRDRVENEAEKDLQCHAPVRLDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQ ..: .. : : : . : . .: ... .... : .. CCDS34 GSERGSTVTRRERLTTLILGRRWRWSRPQIGQSERAGHSQPKMRAHLFSNSWNTSSASF- 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB7 RKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAM .:: .::.::::: :::::::::::::::.:::.:: :.:.:. :.: .::::: ::: CCDS34 -RDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAM 110 120 130 140 150 160 210 220 230 240 250 260 pF1KB7 IYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGED ::.:.:.::: :::.::.:.:..:.. .: . : .. . ..:.. CCDS34 TYNRPDTVYYKLAKKILHAGFKMMSKQ--AALLGNEDTAVEEPVPEVVPVQVETAK---- 170 180 190 200 210 270 280 290 300 310 320 pF1KB7 GGCWQREREDSGDAEAHAFKSPSKENKKKDKDMLEDKFKSNNLEREQEQLDRIVKESGGK . .. : .. . :. .. . : :. :. ... . :. . CCDS34 -----KSKKPSREVISCMFEPEGNACSLTD---------STAEEHVLALVEHAADEARDR 220 230 240 250 260 330 340 350 360 370 380 pF1KB7 LTRRLVNSQCEFERRKPDGTTTLGLLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNTLQGF ..: : ... . .:. ::. .... ..: . : :: :. ...: : .:: :: CCDS34 INRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLSSKLLPGFTTL-GF 270 280 290 300 310 390 400 410 420 430 440 pF1KB7 KEDKRNKVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDSDLPSDFSIHEF :...::::: .:. . .. . . .:.:.....:. .:.::.::... . .:..:: CCDS34 KDERRNKVT---FLS-SATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEF 320 330 340 350 360 370 450 460 470 480 490 500 pF1KB7 LATCQDYPYVMADSLLDVLTKGGHSRTLQEMEMSL-----PEDEGHT-RTL-DTAKEMEQ . .: ..:.::: .: : ::::: .... : ::... :: :... . . CCDS34 VKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLGDSSSSVLE 380 390 400 410 420 430 510 520 530 540 550 560 pF1KB7 ITEVEPPGRLDSSTQDRLIALKAVTNFGVPVEVFDSEEAEIFQKKLDETTRLLRELQEAQ . .. : : . .. ....: . .: ..... .:::::.::..:.::: CCDS34 FMSMK-------SYPDVSVDISMLSSLGKVKKELDPDDSHL---NLDETTKLLQDLHEAQ 440 450 460 470 480 570 580 590 600 610 620 pF1KB7 NERLSTRPPPNMICLLGPSYREMHLAEQVTNNLKELAQQVTPGDIVSTYGVRKAMGISIP :: ..:: :. : . : :..: CCDS34 AERGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT 490 500 510 520 530 540 652 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:00:29 2016 done: Sat Nov 5 10:00:29 2016 Total Scan time: 3.860 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]