FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7893, 588 aa 1>>>pF1KB7893 588 - 588 aa - 588 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7779+/-0.000944; mu= 7.9064+/- 0.057 mean_var=148.4518+/-29.899, 0's: 0 Z-trim(110.3): 87 B-trim: 101 in 2/49 Lambda= 0.105264 statistics sampled from 11434 (11521) to 11434 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.354), width: 16 Scan time: 3.810 The best scores are: opt bits E(32554) CCDS8428.1 TRIM29 gene_id:23650|Hs108|chr11 ( 588) 3944 611.0 1.4e-174 CCDS81637.1 TRIM29 gene_id:23650|Hs108|chr11 ( 327) 2136 336.2 3.8e-92 CCDS11171.1 TRIM16 gene_id:10626|Hs108|chr17 ( 564) 502 88.2 3e-17 CCDS11591.1 TRIM25 gene_id:7706|Hs108|chr17 ( 630) 422 76.1 1.5e-13 CCDS32737.1 TRIM47 gene_id:91107|Hs108|chr17 ( 638) 405 73.5 9e-13 >>CCDS8428.1 TRIM29 gene_id:23650|Hs108|chr11 (588 aa) initn: 3944 init1: 3944 opt: 3944 Z-score: 3247.9 bits: 611.0 E(32554): 1.4e-174 Smith-Waterman score: 3944; 100.0% identity (100.0% similar) in 588 aa overlap (1-588:1-588) 10 20 30 40 50 60 pF1KB7 MEAADASRSNGSSPEARDARSPSGPSGSLENGTKADGKDAKTTNGHGGEAAEGKSLGSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 MEAADASRSNGSSPEARDARSPSGPSGSLENGTKADGKDAKTTNGHGGEAAEGKSLGSAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KPGEGRSALFAGNEWRRPIIQFVESGDDKNSNYFSMDSMEGKRSPYAGLQLGAAKKPPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 KPGEGRSALFAGNEWRRPIIQFVESGDDKNSNYFSMDSMEGKRSPYAGLQLGAAKKPPVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FAEKGELRKSIFSESRKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 FAEKGELRKSIFSESRKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 QKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 TCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 SFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 SFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHED 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 KQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 KQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 MRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 MRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 VRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 VRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSSSFS 490 500 510 520 530 540 550 560 570 580 pF1KB7 LKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP :::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 LKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP 550 560 570 580 >>CCDS81637.1 TRIM29 gene_id:23650|Hs108|chr11 (327 aa) initn: 2136 init1: 2136 opt: 2136 Z-score: 1767.8 bits: 336.2 E(32554): 3.8e-92 Smith-Waterman score: 2136; 100.0% identity (100.0% similar) in 321 aa overlap (268-588:7-327) 240 250 260 270 280 290 pF1KB7 TDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKD :::::::::::::::::::::::::::::: CCDS81 MVPGISETELSLQKEQLQLKIIEIEDEAEKWQKEKD 10 20 30 300 310 320 330 340 350 pF1KB7 RIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVL 40 50 60 70 80 90 360 370 380 390 400 410 pF1KB7 HEDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 HEDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLL 100 110 120 130 140 150 420 430 440 450 460 470 pF1KB7 NVCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 NVCMRHVEKMCKADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTP 160 170 180 190 200 210 480 490 500 510 520 530 pF1KB7 KGGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KGGVRTSYQPSSPGRFTKETTQKNFNNLYGTKGNYTSRVWEYSSSIQNSDNDLPVVQGSS 220 230 240 250 260 270 540 550 560 570 580 pF1KB7 SFSLKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 SFSLKGYPSLMRSQSPKAQPQTWKSGKQTMLSHYRPFYVNKGNGIGSNEAP 280 290 300 310 320 >>CCDS11171.1 TRIM16 gene_id:10626|Hs108|chr17 (564 aa) initn: 520 init1: 247 opt: 502 Z-score: 423.2 bits: 88.2 E(32554): 3e-17 Smith-Waterman score: 502; 33.3% identity (66.7% similar) in 240 aa overlap (169-406:73-309) 140 150 160 170 180 190 pF1KB7 TVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNKQ--KAVKSCLVCQASFCE .::::: :. . . :::::::.:....:: CCDS11 EDVGSSEKLGRETEEQDSDSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCE 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB7 LHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKNHS ::.:: . ...: : ::..: . : ::.: . . :: :: ::: : :::..:. CCDS11 EHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCC-QEHSGHT 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB7 TVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNFRD :... :. .::.::. . .:. :. :. . : .. . ... ::. :..: . CCDS11 IVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGE 170 180 190 200 210 220 320 330 340 350 360 370 pF1KB7 LVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISDSVLF :. ..: . .: ::..:: :..:.. : :. :. ....:: :.. .::..: : CCDS11 LLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQF 230 240 250 260 270 280 380 390 400 410 420 430 pF1KB7 LQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKADLSRNF :.:. . .. .. .:. .: :. . : CCDS11 LEEYCKFKNTEDI--TFPSVYVGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEE 290 300 310 320 330 >>CCDS11591.1 TRIM25 gene_id:7706|Hs108|chr17 (630 aa) initn: 296 init1: 296 opt: 422 Z-score: 356.8 bits: 76.1 E(32554): 1.5e-13 Smith-Waterman score: 422; 28.8% identity (62.9% similar) in 267 aa overlap (166-426:100-357) 140 150 160 170 180 190 pF1KB7 RKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCIGNKQKAVKSCLVCQASFC : . .: :: :. :. :::.::::.:::: CCDS11 CNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCL--KEAAVKTCLVCMASFC 70 80 90 100 110 120 200 210 220 230 240 250 pF1KB7 ELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKNH . ::.::... ::.:: : :.::. ::: :.. :.:: . :::..:. :::. CCDS11 QEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV-EHKTC 130 140 150 160 170 180 260 270 280 290 300 310 pF1KB7 STVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKS--FTTNEKA-ILEQ : ... .:.:. :. : ...: . .:. .. . ..: .. .:.:.:. :.: CCDS11 SPASLSQASADLEATL---RHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQ 190 200 210 220 230 240 320 330 340 350 360 370 pF1KB7 NFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISD .. .. :. .. ....:. . .. .:.. : .. . .. :. :: . : CCDS11 EYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRD 250 260 270 280 290 300 380 390 400 410 420 pF1KB7 SVLFLQEFGALMSNYSLP---PPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCK ::.. . : . . : : . : :.. :. :: ..:..: . :. .... CCDS11 EFEFLEKASKLRGISTKPVYIPEVELNHKLIK--GIHQSTIDLKNEL-KQCIGRLQEPTP 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB7 ADLSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGGVRTSYQPSS CCDS11 SSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGL 370 380 390 400 410 420 >>CCDS32737.1 TRIM47 gene_id:91107|Hs108|chr17 (638 aa) initn: 355 init1: 294 opt: 405 Z-score: 342.8 bits: 73.5 E(32554): 9e-13 Smith-Waterman score: 405; 28.9% identity (56.4% similar) in 266 aa overlap (166-427:122-384) 140 150 160 170 180 190 pF1KB7 RKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCI-GNKQKAVKSCLVCQASF .: : : ::.: : :. ::: : ::: CCDS32 APALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLASF 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB7 CELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKN : :: :: .. :.: :.:. :.: .: :: : . .: .:.....:.: : :::.. CCDS32 CPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLRPLERYCRAERVCLCEACAAQEHRG 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB7 HSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNF : : .:. .: .:.: : .. .. :. . .. ::: .. :. . . : CCDS32 HELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLF 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB7 RDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISDSV : . :. . .: . .:. : . . . . .:. . : . .:. :. .::: CCDS32 ADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADSV 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB7 LFLQEFGAL---MSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKAD ::::. :: . . : : : .. . . :.. .: : .:. . :.. CCDS32 SFLQELLALRLALEDGCGPGPGPPRELSFTKSS--QAVRAVRDMLAVACVNQWEQLRGPG 340 350 360 370 380 440 450 460 470 480 490 pF1KB7 LSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGGVRTSYQPSSPG CCDS32 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG 390 400 410 420 430 440 588 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:18:36 2016 done: Fri Nov 4 21:18:36 2016 Total Scan time: 3.810 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]