FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7895, 588 aa 1>>>pF1KB7895 588 - 588 aa - 588 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5555+/-0.000402; mu= 17.9818+/- 0.025 mean_var=72.4565+/-14.267, 0's: 0 Z-trim(111.6): 24 B-trim: 31 in 1/52 Lambda= 0.150673 statistics sampled from 20272 (20289) to 20272 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.238), width: 16 Scan time: 10.310 The best scores are: opt bits E(85289) NP_005671 (OMIM: 604904) TATA box-binding protein- ( 588) 3987 876.4 0 XP_011508712 (OMIM: 604904) PREDICTED: TATA box-bi ( 588) 3949 868.1 0 XP_011508713 (OMIM: 604904) PREDICTED: TATA box-bi ( 380) 2557 565.4 1.2e-160 NP_001305906 (OMIM: 604904) TATA box-binding prote ( 333) 2234 495.2 1.4e-139 NP_001305905 (OMIM: 604904) TATA box-binding prote ( 333) 2234 495.2 1.4e-139 >>NP_005671 (OMIM: 604904) TATA box-binding protein-asso (588 aa) initn: 3987 init1: 3987 opt: 3987 Z-score: 4682.4 bits: 876.4 E(85289): 0 Smith-Waterman score: 3987; 99.7% identity (100.0% similar) in 588 aa overlap (1-588:1-588) 10 20 30 40 50 60 pF1KB7 MDLEEAEEFKERCTQCAAVSWGLTDEGKYYCTSCHNVTERYQEVTNTDLIPNTQIKALNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDLEEAEEFKERCTQCAAVSWGLTDEGKYYCTSCHNVTERYQEVTNTDLIPNTQIKALNR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GLKKKNNTEKGWDWYVCEGFQYILYQQAEALKNLGVGPELKNDVLHNFWKRYLQKSKQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GLKKKNNTEKGWDWYVCEGFQYILYQQAEALKNLGVGPELKNDVLHNFWKRYLQKSKQAY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CKNPVYTTGRKPTVLEDNLSHSDWASEPELLSDVSCPPFLESGAESQSDIHTRKPFPVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CKNPVYTTGRKPTVLEDNLSHSDWASEPELLSDVSCPPFLESGAESQSDIHTRKPFPVSK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ASQSETSVCSGSLDGVEYSQRKEKGIVKMTMPQTLAFCYLSLLWQREAITLSDLLRFVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ASQSETSVCSGSLDGVEYSQRKEKGIVKMTMPQTLAFCYLSLLWQREAITLSDLLRFVEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 DHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTIEVGTFLDLPRFPDITEDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTIEVGTFLDLPRFPDITEDC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 YLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPIAKMAKAVKYDVQAVA ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: NP_005 YLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPIAKMAKTVKYDVQAVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 IIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQIMKKAFDEKKQKWEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQIMKKAFDEKKQKWEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 ARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVDSTATAGKKSPSSFQFNWT :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: NP_005 ARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVESTATAGKKSPSSFQFNWT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 EEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCTHVTTYEESNYSLSYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCTHVTTYEESNYSLSYQ 490 500 510 520 530 540 550 560 570 580 pF1KB7 FILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKVRRH :::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKVRRH 550 560 570 580 >>XP_011508712 (OMIM: 604904) PREDICTED: TATA box-bindin (588 aa) initn: 3949 init1: 3949 opt: 3949 Z-score: 4637.7 bits: 868.1 E(85289): 0 Smith-Waterman score: 3949; 99.5% identity (100.0% similar) in 582 aa overlap (7-588:7-588) 10 20 30 40 50 60 pF1KB7 MDLEEAEEFKERCTQCAAVSWGLTDEGKYYCTSCHNVTERYQEVTNTDLIPNTQIKALNR :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHALMEEFKERCTQCAAVSWGLTDEGKYYCTSCHNVTERYQEVTNTDLIPNTQIKALNR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GLKKKNNTEKGWDWYVCEGFQYILYQQAEALKNLGVGPELKNDVLHNFWKRYLQKSKQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLKKKNNTEKGWDWYVCEGFQYILYQQAEALKNLGVGPELKNDVLHNFWKRYLQKSKQAY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CKNPVYTTGRKPTVLEDNLSHSDWASEPELLSDVSCPPFLESGAESQSDIHTRKPFPVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKNPVYTTGRKPTVLEDNLSHSDWASEPELLSDVSCPPFLESGAESQSDIHTRKPFPVSK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ASQSETSVCSGSLDGVEYSQRKEKGIVKMTMPQTLAFCYLSLLWQREAITLSDLLRFVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASQSETSVCSGSLDGVEYSQRKEKGIVKMTMPQTLAFCYLSLLWQREAITLSDLLRFVEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 DHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTIEVGTFLDLPRFPDITEDC :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: XP_011 DHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTVEVGTFLDLPRFPDITEDC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 YLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPIAKMAKAVKYDVQAVA ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_011 YLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPIAKMAKTVKYDVQAVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 IIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQIMKKAFDEKKQKWEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQIMKKAFDEKKQKWEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 ARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVDSTATAGKKSPSSFQFNWT :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: XP_011 ARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVESTATAGKKSPSSFQFNWT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 EEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCTHVTTYEESNYSLSYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCTHVTTYEESNYSLSYQ 490 500 510 520 530 540 550 560 570 580 pF1KB7 FILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKVRRH :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKVRRH 550 560 570 580 >>XP_011508713 (OMIM: 604904) PREDICTED: TATA box-bindin (380 aa) initn: 2557 init1: 2557 opt: 2557 Z-score: 3005.2 bits: 565.4 E(85289): 1.2e-160 Smith-Waterman score: 2557; 99.2% identity (100.0% similar) in 380 aa overlap (209-588:1-380) 180 190 200 210 220 230 pF1KB7 SKASQSETSVCSGSLDGVEYSQRKEKGIVKMTMPQTLAFCYLSLLWQREAITLSDLLRFV :::::::::::::::::::::::::::::: XP_011 MTMPQTLAFCYLSLLWQREAITLSDLLRFV 10 20 30 240 250 260 270 280 290 pF1KB7 EEDHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTIEVGTFLDLPRFPDITE :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_011 EEDHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTVEVGTFLDLPRFPDITE 40 50 60 70 80 90 300 310 320 330 340 350 pF1KB7 DCYLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPIAKMAKAVKYDVQA ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: XP_011 DCYLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPIAKMAKTVKYDVQA 100 110 120 130 140 150 360 370 380 390 400 410 pF1KB7 VAIIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQIMKKAFDEKKQKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAIIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQIMKKAFDEKKQKW 160 170 180 190 200 210 420 430 440 450 460 470 pF1KB7 EEARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVDSTATAGKKSPSSFQFN :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_011 EEARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVESTATAGKKSPSSFQFN 220 230 240 250 260 270 480 490 500 510 520 530 pF1KB7 WTEEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCTHVTTYEESNYSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTEEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCTHVTTYEESNYSLS 280 290 300 310 320 330 540 550 560 570 580 pF1KB7 YQFILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKVRRH :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQFILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKVRRH 340 350 360 370 380 >>NP_001305906 (OMIM: 604904) TATA box-binding protein-a (333 aa) initn: 2234 init1: 2234 opt: 2234 Z-score: 2626.7 bits: 495.2 E(85289): 1.4e-139 Smith-Waterman score: 2234; 99.4% identity (100.0% similar) in 333 aa overlap (256-588:1-333) 230 240 250 260 270 280 pF1KB7 REAITLSDLLRFVEEDHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTIEVG :::::::::::::::::::::::::::::: NP_001 MKLYGRDRGIFGIESWPDYEDIYKKTIEVG 10 20 30 290 300 310 320 330 340 pF1KB7 TFLDLPRFPDITEDCYLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFLDLPRFPDITEDCYLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPI 40 50 60 70 80 90 350 360 370 380 390 400 pF1KB7 AKMAKAVKYDVQAVAIIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQ :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKMAKTVKYDVQAVAIIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQ 100 110 120 130 140 150 410 420 430 440 450 460 pF1KB7 IMKKAFDEKKQKWEEARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVDSTA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: NP_001 IMKKAFDEKKQKWEEARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVESTA 160 170 180 190 200 210 470 480 490 500 510 520 pF1KB7 TAGKKSPSSFQFNWTEEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAGKKSPSSFQFNWTEEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCT 220 230 240 250 260 270 530 540 550 560 570 580 pF1KB7 HVTTYEESNYSLSYQFILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVTTYEESNYSLSYQFILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKV 280 290 300 310 320 330 pF1KB7 RRH ::: NP_001 RRH >>NP_001305905 (OMIM: 604904) TATA box-binding protein-a (333 aa) initn: 2234 init1: 2234 opt: 2234 Z-score: 2626.7 bits: 495.2 E(85289): 1.4e-139 Smith-Waterman score: 2234; 99.4% identity (100.0% similar) in 333 aa overlap (256-588:1-333) 230 240 250 260 270 280 pF1KB7 REAITLSDLLRFVEEDHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTIEVG :::::::::::::::::::::::::::::: NP_001 MKLYGRDRGIFGIESWPDYEDIYKKTIEVG 10 20 30 290 300 310 320 330 340 pF1KB7 TFLDLPRFPDITEDCYLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFLDLPRFPDITEDCYLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPI 40 50 60 70 80 90 350 360 370 380 390 400 pF1KB7 AKMAKAVKYDVQAVAIIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQ :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKMAKTVKYDVQAVAIIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQ 100 110 120 130 140 150 410 420 430 440 450 460 pF1KB7 IMKKAFDEKKQKWEEARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVDSTA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: NP_001 IMKKAFDEKKQKWEEARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVESTA 160 170 180 190 200 210 470 480 490 500 510 520 pF1KB7 TAGKKSPSSFQFNWTEEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAGKKSPSSFQFNWTEEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCT 220 230 240 250 260 270 530 540 550 560 570 580 pF1KB7 HVTTYEESNYSLSYQFILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVTTYEESNYSLSYQFILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKV 280 290 300 310 320 330 pF1KB7 RRH ::: NP_001 RRH 588 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:24:34 2016 done: Sat Nov 5 16:24:36 2016 Total Scan time: 10.310 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]