FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7905, 124 aa 1>>>pF1KB7905 124 - 124 aa - 124 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9232+/-0.000286; mu= 13.0415+/- 0.018 mean_var=62.4071+/-11.836, 0's: 0 Z-trim(118.5): 17 B-trim: 73 in 1/50 Lambda= 0.162352 statistics sampled from 31486 (31503) to 31486 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.369), width: 16 Scan time: 4.500 The best scores are: opt bits E(85289) NP_005636 (OMIM: 600774) transcription initiation ( 124) 816 198.7 2e-51 XP_016866861 (OMIM: 602947) PREDICTED: transcripti ( 317) 163 46.0 4.7e-05 NP_003590 (OMIM: 602947) transcription initiation ( 317) 163 46.0 4.7e-05 XP_016866860 (OMIM: 602947) PREDICTED: transcripti ( 317) 163 46.0 4.7e-05 XP_011513254 (OMIM: 602947) PREDICTED: transcripti ( 319) 163 46.0 4.7e-05 XP_011513252 (OMIM: 602947) PREDICTED: transcripti ( 319) 163 46.0 4.7e-05 XP_011513256 (OMIM: 602947) PREDICTED: transcripti ( 319) 163 46.0 4.7e-05 XP_011513255 (OMIM: 602947) PREDICTED: transcripti ( 319) 163 46.0 4.7e-05 XP_011513253 (OMIM: 602947) PREDICTED: transcripti ( 319) 163 46.0 4.7e-05 XP_016866862 (OMIM: 602947) PREDICTED: transcripti ( 296) 130 38.3 0.0095 >>NP_005636 (OMIM: 600774) transcription initiation fact (124 aa) initn: 816 init1: 816 opt: 816 Z-score: 1044.2 bits: 198.7 E(85289): 2e-51 Smith-Waterman score: 816; 100.0% identity (100.0% similar) in 124 aa overlap (1-124:1-124) 10 20 30 40 50 60 pF1KB7 MADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VIEFITEMTHKAMSIGRQGRVQVEDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VIEFITEMTHKAMSIGRQGRVQVEDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFDEA 70 80 90 100 110 120 pF1KB7 NYGS :::: NP_005 NYGS >>XP_016866861 (OMIM: 602947) PREDICTED: transcription i (317 aa) initn: 162 init1: 95 opt: 163 Z-score: 211.7 bits: 46.0 E(85289): 4.7e-05 Smith-Waterman score: 163; 31.9% identity (67.0% similar) in 91 aa overlap (32-119:26-116) 10 20 30 40 50 60 pF1KB7 ADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLV :. ::. :::..:: . : :.. ..::.: XP_016 MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVV 10 20 30 40 50 70 80 90 100 110 pF1KB7 IEFITEMTHKAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFD . .. ..: .. : .:: . ::..::.::: .:. :. . . . .. :..: XP_016 HTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGID 60 70 80 90 100 110 120 pF1KB7 EANYGS : XP_016 EDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTR 120 130 140 150 160 170 >>NP_003590 (OMIM: 602947) transcription initiation prot (317 aa) initn: 162 init1: 95 opt: 163 Z-score: 211.7 bits: 46.0 E(85289): 4.7e-05 Smith-Waterman score: 163; 31.9% identity (67.0% similar) in 91 aa overlap (32-119:26-116) 10 20 30 40 50 60 pF1KB7 ADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLV :. ::. :::..:: . : :.. ..::.: NP_003 MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVV 10 20 30 40 50 70 80 90 100 110 pF1KB7 IEFITEMTHKAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFD . .. ..: .. : .:: . ::..::.::: .:. :. . . . .. :..: NP_003 HTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGID 60 70 80 90 100 110 120 pF1KB7 EANYGS : NP_003 EDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTR 120 130 140 150 160 170 >>XP_016866860 (OMIM: 602947) PREDICTED: transcription i (317 aa) initn: 162 init1: 95 opt: 163 Z-score: 211.7 bits: 46.0 E(85289): 4.7e-05 Smith-Waterman score: 163; 31.9% identity (67.0% similar) in 91 aa overlap (32-119:26-116) 10 20 30 40 50 60 pF1KB7 ADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLV :. ::. :::..:: . : :.. ..::.: XP_016 MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVV 10 20 30 40 50 70 80 90 100 110 pF1KB7 IEFITEMTHKAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFD . .. ..: .. : .:: . ::..::.::: .:. :. . . . .. :..: XP_016 HTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGID 60 70 80 90 100 110 120 pF1KB7 EANYGS : XP_016 EDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTR 120 130 140 150 160 170 >>XP_011513254 (OMIM: 602947) PREDICTED: transcription i (319 aa) initn: 162 init1: 95 opt: 163 Z-score: 211.7 bits: 46.0 E(85289): 4.7e-05 Smith-Waterman score: 163; 31.9% identity (67.0% similar) in 91 aa overlap (32-119:26-116) 10 20 30 40 50 60 pF1KB7 ADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLV :. ::. :::..:: . : :.. ..::.: XP_011 MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVV 10 20 30 40 50 70 80 90 100 110 pF1KB7 IEFITEMTHKAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFD . .. ..: .. : .:: . ::..::.::: .:. :. . . . .. :..: XP_011 HTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGID 60 70 80 90 100 110 120 pF1KB7 EANYGS : XP_011 EDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTR 120 130 140 150 160 170 >>XP_011513252 (OMIM: 602947) PREDICTED: transcription i (319 aa) initn: 162 init1: 95 opt: 163 Z-score: 211.7 bits: 46.0 E(85289): 4.7e-05 Smith-Waterman score: 163; 31.9% identity (67.0% similar) in 91 aa overlap (32-119:26-116) 10 20 30 40 50 60 pF1KB7 ADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLV :. ::. :::..:: . : :.. ..::.: XP_011 MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVV 10 20 30 40 50 70 80 90 100 110 pF1KB7 IEFITEMTHKAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFD . .. ..: .. : .:: . ::..::.::: .:. :. . . . .. :..: XP_011 HTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGID 60 70 80 90 100 110 120 pF1KB7 EANYGS : XP_011 EDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTR 120 130 140 150 160 170 >>XP_011513256 (OMIM: 602947) PREDICTED: transcription i (319 aa) initn: 162 init1: 95 opt: 163 Z-score: 211.7 bits: 46.0 E(85289): 4.7e-05 Smith-Waterman score: 163; 31.9% identity (67.0% similar) in 91 aa overlap (32-119:26-116) 10 20 30 40 50 60 pF1KB7 ADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLV :. ::. :::..:: . : :.. ..::.: XP_011 MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVV 10 20 30 40 50 70 80 90 100 110 pF1KB7 IEFITEMTHKAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFD . .. ..: .. : .:: . ::..::.::: .:. :. . . . .. :..: XP_011 HTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGID 60 70 80 90 100 110 120 pF1KB7 EANYGS : XP_011 EDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTR 120 130 140 150 160 170 >>XP_011513255 (OMIM: 602947) PREDICTED: transcription i (319 aa) initn: 162 init1: 95 opt: 163 Z-score: 211.7 bits: 46.0 E(85289): 4.7e-05 Smith-Waterman score: 163; 31.9% identity (67.0% similar) in 91 aa overlap (32-119:26-116) 10 20 30 40 50 60 pF1KB7 ADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLV :. ::. :::..:: . : :.. ..::.: XP_011 MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVV 10 20 30 40 50 70 80 90 100 110 pF1KB7 IEFITEMTHKAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFD . .. ..: .. : .:: . ::..::.::: .:. :. . . . .. :..: XP_011 HTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGID 60 70 80 90 100 110 120 pF1KB7 EANYGS : XP_011 EDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTR 120 130 140 150 160 170 >>XP_011513253 (OMIM: 602947) PREDICTED: transcription i (319 aa) initn: 162 init1: 95 opt: 163 Z-score: 211.7 bits: 46.0 E(85289): 4.7e-05 Smith-Waterman score: 163; 31.9% identity (67.0% similar) in 91 aa overlap (32-119:26-116) 10 20 30 40 50 60 pF1KB7 ADEEEDPTFEEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLV :. ::. :::..:: . : :.. ..::.: XP_011 MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVV 10 20 30 40 50 70 80 90 100 110 pF1KB7 IEFITEMTHKAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFD . .. ..: .. : .:: . ::..::.::: .:. :. . . . .. :..: XP_011 HTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGID 60 70 80 90 100 110 120 pF1KB7 EANYGS : XP_011 EDDLLEDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTR 120 130 140 150 160 170 >>XP_016866862 (OMIM: 602947) PREDICTED: transcription i (296 aa) initn: 115 init1: 81 opt: 130 Z-score: 170.4 bits: 38.3 E(85289): 0.0095 Smith-Waterman score: 130; 29.3% identity (65.9% similar) in 82 aa overlap (41-119:14-95) 20 30 40 50 60 70 pF1KB7 EEENEEIGGGAEGGQGKRKRLFSKELRCMMYGFGDDQNPYTESVDILEDLVIEFITEMTH :..:: . : :.. ..::.: . .. . XP_016 MVVFGTTFFNFDRYSLGDARRPLHETAVLVEDVVHTQLINLLQ 10 20 30 40 80 90 100 110 120 pF1KB7 KAMSIG--RQGRVQV-EDIVFLIRKDPRKFARVKDLLTMNEELKRARKAFDEANYGS .: .. : .:: . ::..::.::: .:. :. . . . .. :..:: XP_016 QAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGIDEDDLLEDKL 50 60 70 80 90 100 XP_016 SGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTRIMDSAQYAE 110 120 130 140 150 160 124 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:47:57 2016 done: Sat Nov 5 19:47:57 2016 Total Scan time: 4.500 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]