FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7911, 147 aa 1>>>pF1KB7911 147 - 147 aa - 147 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2011+/-0.000398; mu= -5.2236+/- 0.025 mean_var=242.7538+/-48.740, 0's: 0 Z-trim(120.7): 8 B-trim: 786 in 2/52 Lambda= 0.082317 statistics sampled from 36219 (36227) to 36219 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.425), width: 16 Scan time: 4.690 The best scores are: opt bits E(85289) NP_001265184 (OMIM: 607267) DNA polymerase epsilon ( 147) 924 121.4 5.4e-28 NP_059139 (OMIM: 607267) DNA polymerase epsilon su ( 147) 924 121.4 5.4e-28 NP_006157 (OMIM: 189904) nuclear transcription fac ( 207) 233 39.4 0.0035 XP_005268966 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 233 39.4 0.0035 XP_005268965 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 233 39.4 0.0035 XP_005268967 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 233 39.4 0.0035 >>NP_001265184 (OMIM: 607267) DNA polymerase epsilon sub (147 aa) initn: 924 init1: 924 opt: 924 Z-score: 623.6 bits: 121.4 E(85289): 5.4e-28 Smith-Waterman score: 924; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB7 MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD 70 80 90 100 110 120 130 140 pF1KB7 KSRDEDNDEDEERLEEEEQNEEEEVDN ::::::::::::::::::::::::::: NP_001 KSRDEDNDEDEERLEEEEQNEEEEVDN 130 140 >>NP_059139 (OMIM: 607267) DNA polymerase epsilon subuni (147 aa) initn: 924 init1: 924 opt: 924 Z-score: 623.6 bits: 121.4 E(85289): 5.4e-28 Smith-Waterman score: 924; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB7 MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_059 MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_059 RKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQD 70 80 90 100 110 120 130 140 pF1KB7 KSRDEDNDEDEERLEEEEQNEEEEVDN ::::::::::::::::::::::::::: NP_059 KSRDEDNDEDEERLEEEEQNEEEEVDN 130 140 >>NP_006157 (OMIM: 189904) nuclear transcription factor (207 aa) initn: 217 init1: 217 opt: 233 Z-score: 178.1 bits: 39.4 E(85289): 0.0035 Smith-Waterman score: 233; 38.1% identity (71.1% similar) in 97 aa overlap (4-100:53-149) 10 20 30 pF1KB7 MAERPEDLNLPNAVITRIIKEALPDGVNISKEA : .:. :: : ..::.:.:.:. .:.:.: NP_006 GGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 RSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYR . ... .: :. . :: :.. . ::::.:. :.: :: . :. .: ::: :. .: NP_006 KECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFR 90 100 110 120 130 140 100 110 120 130 140 pF1KB7 REQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN . .::.: NP_006 EAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ 150 160 170 180 190 200 >>XP_005268966 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa) initn: 217 init1: 217 opt: 233 Z-score: 178.1 bits: 39.4 E(85289): 0.0035 Smith-Waterman score: 233; 38.1% identity (71.1% similar) in 97 aa overlap (4-100:54-150) 10 20 30 pF1KB7 MAERPEDLNLPNAVITRIIKEALPDGVNISKEA : .:. :: : ..::.:.:.:. .:.:.: XP_005 GGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 RSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYR . ... .: :. . :: :.. . ::::.:. :.: :: . :. .: ::: :. .: XP_005 KECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFR 90 100 110 120 130 140 100 110 120 130 140 pF1KB7 REQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN . .::.: XP_005 EAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ 150 160 170 180 190 200 >>XP_005268965 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa) initn: 217 init1: 217 opt: 233 Z-score: 178.1 bits: 39.4 E(85289): 0.0035 Smith-Waterman score: 233; 38.1% identity (71.1% similar) in 97 aa overlap (4-100:54-150) 10 20 30 pF1KB7 MAERPEDLNLPNAVITRIIKEALPDGVNISKEA : .:. :: : ..::.:.:.:. .:.:.: XP_005 GGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 RSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYR . ... .: :. . :: :.. . ::::.:. :.: :: . :. .: ::: :. .: XP_005 KECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFR 90 100 110 120 130 140 100 110 120 130 140 pF1KB7 REQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN . .::.: XP_005 EAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ 150 160 170 180 190 200 >>XP_005268967 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa) initn: 217 init1: 217 opt: 233 Z-score: 178.1 bits: 39.4 E(85289): 0.0035 Smith-Waterman score: 233; 38.1% identity (71.1% similar) in 97 aa overlap (4-100:54-150) 10 20 30 pF1KB7 MAERPEDLNLPNAVITRIIKEALPDGVNISKEA : .:. :: : ..::.:.:.:. .:.:.: XP_005 GGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 RSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYR . ... .: :. . :: :.. . ::::.:. :.: :: . :. .: ::: :. .: XP_005 KECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFR 90 100 110 120 130 140 100 110 120 130 140 pF1KB7 REQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN . .::.: XP_005 EAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ 150 160 170 180 190 200 147 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:35:23 2016 done: Sat Nov 5 14:35:24 2016 Total Scan time: 4.690 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]