FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7917, 370 aa 1>>>pF1KB7917 370 - 370 aa - 370 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1968+/-0.000742; mu= 16.5764+/- 0.044 mean_var=60.9780+/-12.500, 0's: 0 Z-trim(108.3): 53 B-trim: 428 in 1/50 Lambda= 0.164243 statistics sampled from 10055 (10111) to 10055 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.311), width: 16 Scan time: 2.780 The best scores are: opt bits E(32554) CCDS13424.1 UBE2V1 gene_id:387522|Hs108|chr20 ( 370) 2600 624.5 4.7e-179 CCDS13428.1 TMEM189 gene_id:387521|Hs108|chr20 ( 270) 1664 402.6 2.1e-112 CCDS54473.1 TMEM189 gene_id:387521|Hs108|chr20 ( 267) 1629 394.3 6.5e-110 CCDS33483.1 UBE2V1 gene_id:7335|Hs108|chr20 ( 147) 957 234.9 3.3e-62 CCDS13426.1 UBE2V1 gene_id:7335|Hs108|chr20 ( 170) 956 234.7 4.5e-62 CCDS43738.1 UBE2V2 gene_id:7336|Hs108|chr8 ( 145) 892 219.5 1.4e-57 CCDS74740.1 UBE2V1 gene_id:7335|Hs108|chr20 ( 105) 716 177.8 3.9e-45 CCDS13427.1 UBE2V1 gene_id:7335|Hs108|chr20 ( 103) 614 153.6 7.2e-38 CCDS58775.1 UBE2V1 gene_id:7335|Hs108|chr20 ( 105) 350 91.0 5e-19 >>CCDS13424.1 UBE2V1 gene_id:387522|Hs108|chr20 (370 aa) initn: 2600 init1: 2600 opt: 2600 Z-score: 3328.1 bits: 624.5 E(32554): 4.7e-179 Smith-Waterman score: 2600; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370) 10 20 30 40 50 60 pF1KB7 MAGAENWPGQQLELDEDEASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MAGAENWPGQQLELDEDEASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPIVGKAFIRPFREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPIVGKAFIRPFREH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 HIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGVKVPRNFRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGVKVPRNFRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 APPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 APPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLP 310 320 330 340 350 360 370 pF1KB7 QPPEGQCYSN :::::::::: CCDS13 QPPEGQCYSN 370 >>CCDS13428.1 TMEM189 gene_id:387521|Hs108|chr20 (270 aa) initn: 1653 init1: 1653 opt: 1664 Z-score: 2131.5 bits: 402.6 E(32554): 2.1e-112 Smith-Waterman score: 1664; 93.3% identity (95.7% similar) in 255 aa overlap (1-250:1-255) 10 20 30 40 50 60 pF1KB7 MAGAENWPGQQLELDEDEASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MAGAENWPGQQLELDEDEASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPIVGKAFIRPFREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPIVGKAFIRPFREH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 HIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGT 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 FTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTG-VKVPRN-- ::::::::::::::::::::::::::::::::::::::::::::::::::: .. : . CCDS13 FTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGWLNYPLEKI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB7 --FRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECG .: ::.: .: : CCDS13 GFWRRLEDLIQGLTGEKPRADDMKWAQKIK 250 260 270 >>CCDS54473.1 TMEM189 gene_id:387521|Hs108|chr20 (267 aa) initn: 1620 init1: 877 opt: 1629 Z-score: 2086.8 bits: 394.3 E(32554): 6.5e-110 Smith-Waterman score: 1629; 92.2% identity (94.5% similar) in 255 aa overlap (1-250:1-252) 10 20 30 40 50 60 pF1KB7 MAGAENWPGQQLELDEDEASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MAGAENWPGQQLELDEDEASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPIVGKAFIRPFREH :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: CCDS54 LVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPI---AFIRPFREH 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 HIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGT 120 130 140 150 160 170 190 200 210 220 230 pF1KB7 FTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTG-VKVPRN-- ::::::::::::::::::::::::::::::::::::::::::::::::::: .. : . CCDS54 FTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGWLNYPLEKI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 --FRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECG .: ::.: .: : CCDS54 GFWRRLEDLIQGLTGEKPRADDMKWAQKIK 240 250 260 >>CCDS33483.1 UBE2V1 gene_id:7335|Hs108|chr20 (147 aa) initn: 957 init1: 957 opt: 957 Z-score: 1230.2 bits: 234.9 E(32554): 3.3e-62 Smith-Waterman score: 957; 99.3% identity (100.0% similar) in 141 aa overlap (230-370:7-147) 200 210 220 230 240 250 pF1KB7 TLLQDWHVILPRKHHRIHHVSPHETYFCITTGVKVPRNFRLLEELEEGQKGVGDGTVSWG .::::::::::::::::::::::::::::: CCDS33 MAATTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWG 10 20 30 260 270 280 290 300 310 pF1KB7 LEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSS 40 50 60 70 80 90 320 330 340 350 360 370 pF1KB7 NGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 NGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN 100 110 120 130 140 >>CCDS13426.1 UBE2V1 gene_id:7335|Hs108|chr20 (170 aa) initn: 955 init1: 955 opt: 956 Z-score: 1228.0 bits: 234.7 E(32554): 4.5e-62 Smith-Waterman score: 956; 96.6% identity (97.3% similar) in 146 aa overlap (225-370:27-170) 200 210 220 230 240 250 pF1KB7 LPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGVKVPRNFRLLEELEEGQKGVGDG . : :::::::::::::::::::::::: CCDS13 MPGEVQASYLKSQSKLSDEGRLEPRKFHC--KGVKVPRNFRLLEELEEGQKGVGDG 10 20 30 40 50 260 270 280 290 300 310 pF1KB7 TVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMN 60 70 80 90 100 110 320 330 340 350 360 370 pF1KB7 GVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN 120 130 140 150 160 170 >>CCDS43738.1 UBE2V2 gene_id:7336|Hs108|chr8 (145 aa) initn: 906 init1: 886 opt: 892 Z-score: 1147.1 bits: 219.5 E(32554): 1.4e-57 Smith-Waterman score: 892; 90.2% identity (96.5% similar) in 143 aa overlap (228-370:3-145) 200 210 220 230 240 250 pF1KB7 WVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGVKVPRNFRLLEELEEGQKGVGDGTVS ..:::::::::::::::::::::::::::: CCDS43 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVS 10 20 30 260 270 280 290 300 310 pF1KB7 WGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVN :::::::::::::::::::::::: :::::::::.::::::::::: :::::::::::.: CCDS43 WGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGIN 40 50 60 70 80 90 320 330 340 350 360 370 pF1KB7 SSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN .:.:.:: :.: ::::::::::::::::::::::::::::::::::::: :.: CCDS43 NSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN 100 110 120 130 140 >>CCDS74740.1 UBE2V1 gene_id:7335|Hs108|chr20 (105 aa) initn: 716 init1: 716 opt: 716 Z-score: 923.8 bits: 177.8 E(32554): 3.9e-45 Smith-Waterman score: 716; 100.0% identity (100.0% similar) in 105 aa overlap (266-370:1-105) 240 250 260 270 280 290 pF1KB7 RNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECG :::::::::::::::::::::::::::::: CCDS74 MTLTRWTGMIIGPPRTIYENRIYSLKIECG 10 20 30 300 310 320 330 340 350 pF1KB7 PKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKE 40 50 60 70 80 90 360 370 pF1KB7 NMKLPQPPEGQCYSN ::::::::::::::: CCDS74 NMKLPQPPEGQCYSN 100 >>CCDS13427.1 UBE2V1 gene_id:7335|Hs108|chr20 (103 aa) initn: 610 init1: 610 opt: 614 Z-score: 793.3 bits: 153.6 E(32554): 7.2e-38 Smith-Waterman score: 614; 87.9% identity (92.5% similar) in 107 aa overlap (264-370:3-103) 240 250 260 270 280 290 pF1KB7 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIE ::..: .:. .::::::::::::: CCDS13 MKEDLNLENFTA------KTIYENRIYSLKIE 10 20 300 310 320 330 340 350 pF1KB7 CGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 CGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMS 30 40 50 60 70 80 360 370 pF1KB7 KENMKLPQPPEGQCYSN ::::::::::::::::: CCDS13 KENMKLPQPPEGQCYSN 90 100 >>CCDS58775.1 UBE2V1 gene_id:7335|Hs108|chr20 (105 aa) initn: 659 init1: 350 opt: 350 Z-score: 455.1 bits: 91.0 E(32554): 5e-19 Smith-Waterman score: 579; 69.5% identity (70.2% similar) in 141 aa overlap (230-370:7-105) 200 210 220 230 240 250 pF1KB7 TLLQDWHVILPRKHHRIHHVSPHETYFCITTGVKVPRNFRLLEELEEGQKGVGDGTVSWG .::::::::::::::::::::::::::::: CCDS58 MAATTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWG 10 20 30 260 270 280 290 300 310 pF1KB7 LEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSS ::::::::::::::::::::: CCDS58 LEDDEDMTLTRWTGMIIGPPR--------------------------------------- 40 50 320 330 340 350 360 370 pF1KB7 NGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN :::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ---VDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN 60 70 80 90 100 370 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:48:41 2016 done: Sat Nov 5 19:48:41 2016 Total Scan time: 2.780 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]