FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7918, 346 aa 1>>>pF1KB7918 346 - 346 aa - 346 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6087+/-0.000327; mu= 8.8253+/- 0.021 mean_var=186.0424+/-37.662, 0's: 0 Z-trim(121.4): 89 B-trim: 0 in 0/56 Lambda= 0.094030 statistics sampled from 37904 (38046) to 37904 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.446), width: 16 Scan time: 9.360 The best scores are: opt bits E(85289) NP_003358 (OMIM: 600390) upstream stimulatory fact ( 346) 2271 319.7 5.8e-87 XP_005259254 (OMIM: 600390) PREDICTED: upstream st ( 351) 2093 295.6 1.1e-79 XP_011525563 (OMIM: 600390) PREDICTED: upstream st ( 244) 1598 228.3 1.4e-59 XP_011525562 (OMIM: 600390) PREDICTED: upstream st ( 258) 1596 228.0 1.7e-59 NP_997174 (OMIM: 600390) upstream stimulatory fact ( 279) 1332 192.2 1.1e-48 XP_016882688 (OMIM: 600390) PREDICTED: upstream st ( 284) 1154 168.1 2.1e-41 NP_001308079 (OMIM: 600390) upstream stimulatory f ( 215) 937 138.6 1.2e-32 NP_996888 (OMIM: 191523,602491) upstream stimulato ( 251) 756 114.1 3.4e-25 NP_009053 (OMIM: 191523,602491) upstream stimulato ( 310) 756 114.1 4e-25 NP_001263302 (OMIM: 191523,602491) upstream stimul ( 310) 756 114.1 4e-25 >>NP_003358 (OMIM: 600390) upstream stimulatory factor 2 (346 aa) initn: 2271 init1: 2271 opt: 2271 Z-score: 1682.2 bits: 319.7 E(85289): 5.8e-87 Smith-Waterman score: 2271; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET 250 260 270 280 290 300 310 320 330 340 pF1KB7 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ :::::::::::::::::::::::::::::::::::::::::::::: NP_003 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ 310 320 330 340 >>XP_005259254 (OMIM: 600390) PREDICTED: upstream stimul (351 aa) initn: 2121 init1: 2093 opt: 2093 Z-score: 1551.6 bits: 295.6 E(85289): 1.1e-79 Smith-Waterman score: 2093; 99.7% identity (100.0% similar) in 318 aa overlap (1-318:1-318) 10 20 30 40 50 60 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET 250 260 270 280 290 300 310 320 330 340 pF1KB7 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ :::::::::::::::::. XP_005 FKEAERLQMDNELLRQQVGAGPGAGQGPGAPDARRWPSAPLTSVVSARSRS 310 320 330 340 350 >>XP_011525563 (OMIM: 600390) PREDICTED: upstream stimul (244 aa) initn: 1598 init1: 1598 opt: 1598 Z-score: 1190.7 bits: 228.3 E(85289): 1.4e-59 Smith-Waterman score: 1598; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243) 10 20 30 40 50 60 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET ::: XP_011 NEVP >>XP_011525562 (OMIM: 600390) PREDICTED: upstream stimul (258 aa) initn: 1593 init1: 1593 opt: 1596 Z-score: 1189.0 bits: 228.0 E(85289): 1.7e-59 Smith-Waterman score: 1596; 95.7% identity (96.5% similar) in 255 aa overlap (1-255:1-255) 10 20 30 40 50 60 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET :: : .:. XP_011 NEGLWSRWGLHCSWVSLG 250 >>NP_997174 (OMIM: 600390) upstream stimulatory factor 2 (279 aa) initn: 1332 init1: 1332 opt: 1332 Z-score: 995.0 bits: 192.2 E(85289): 1.1e-48 Smith-Waterman score: 1688; 80.6% identity (80.6% similar) in 346 aa overlap (1-346:1-279) 10 20 30 40 50 60 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD :::::::::::::::: NP_997 DHNIQYQFRTETNGGQ-------------------------------------------- 70 130 140 150 160 170 180 pF1KB7 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA ::::::::::::::::::::::::::::::::::::: NP_997 -----------------------AVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA 80 90 100 110 190 200 210 220 230 240 pF1KB7 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB7 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET 180 190 200 210 220 230 310 320 330 340 pF1KB7 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ :::::::::::::::::::::::::::::::::::::::::::::: NP_997 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ 240 250 260 270 >>XP_016882688 (OMIM: 600390) PREDICTED: upstream stimul (284 aa) initn: 1650 init1: 1154 opt: 1154 Z-score: 864.4 bits: 168.1 E(85289): 2.1e-41 Smith-Waterman score: 1510; 78.6% identity (78.9% similar) in 318 aa overlap (1-318:1-251) 10 20 30 40 50 60 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD :::::::::::::::: XP_016 DHNIQYQFRTETNGGQ-------------------------------------------- 70 130 140 150 160 170 180 pF1KB7 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA ::::::::::::::::::::::::::::::::::::: XP_016 -----------------------AVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA 80 90 100 110 190 200 210 220 230 240 pF1KB7 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB7 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET 180 190 200 210 220 230 310 320 330 340 pF1KB7 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ :::::::::::::::::. XP_016 FKEAERLQMDNELLRQQVGAGPGAGQGPGAPDARRWPSAPLTSVVSARSRS 240 250 260 270 280 >>NP_001308079 (OMIM: 600390) upstream stimulatory facto (215 aa) initn: 928 init1: 928 opt: 937 Z-score: 706.8 bits: 138.6 E(85289): 1.2e-32 Smith-Waterman score: 1149; 62.1% identity (62.1% similar) in 346 aa overlap (1-346:1-215) 10 20 30 40 50 60 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVD :::::::::::::::: NP_001 DHNIQYQFRTETNGGQ-------------------------------------------- 70 130 140 150 160 170 180 pF1KB7 GAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA NP_001 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KB7 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH ::::::::::::::::::::::::::::::::: NP_001 ---------------------------TGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH 80 90 100 250 260 270 280 290 300 pF1KB7 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQET 110 120 130 140 150 160 310 320 330 340 pF1KB7 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ :::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ 170 180 190 200 210 >>NP_996888 (OMIM: 191523,602491) upstream stimulatory f (251 aa) initn: 918 init1: 749 opt: 756 Z-score: 573.3 bits: 114.1 E(85289): 3.4e-25 Smith-Waterman score: 846; 51.3% identity (73.6% similar) in 277 aa overlap (79-340:2-245) 50 60 70 80 90 100 pF1KB7 VAITSVQQAAFGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFA :::.::..:::::: . .::.: NP_996 MYRVIQVSEGQLDGQTEGTGAIS-------- 10 20 110 120 130 140 150 160 pF1KB7 GGQQAVTQVGVDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFA : ::. :. ::::. :.. . .:....:.... NP_996 -GY----------------PATQSMTQ--------AVIQGAFTSDDAVDTEGTAAETHYT 30 40 50 170 180 190 200 210 pF1KB7 YFPASSVGD--------TTA--VSVQTTD----QSLQAG-GQFYVMMTPQDVLQTGTQRT :::...::: .:: :..: .. :. : :::.:::.::.::: :.::. NP_996 YFPSTAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRS 60 70 80 90 100 110 220 230 240 250 260 270 pF1KB7 IAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTG ::::::::::: .. :: :::.::::::::::::::::::::::::::::::. ...:.: NP_996 IAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSG 120 130 140 150 160 170 280 290 300 310 320 330 pF1KB7 ASKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQ :::::::::::::.::::.:.:..: .. ..::.::..::::.:.:::.: ::::::. NP_996 QSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLR 180 190 200 210 220 230 340 pF1KB7 QHNLEMVGEGTRQ .:.::.: NP_996 HHGLEVVIKNDSN 240 250 >>NP_009053 (OMIM: 191523,602491) upstream stimulatory f (310 aa) initn: 1000 init1: 749 opt: 756 Z-score: 572.1 bits: 114.1 E(85289): 4e-25 Smith-Waterman score: 1005; 51.8% identity (74.4% similar) in 336 aa overlap (22-340:4-304) 10 20 30 40 50 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEG-VELQEGGDGPGAEEQTAVAITSVQQAA- ..: :.::: :..:::. . : :. :.:::.:.:.:: NP_009 MKGQQKTAETEEGTVQIQEGAVATG-EDPTSVAIASIQSAAT 10 20 30 40 60 70 80 90 100 110 pF1KB7 FGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVG : : :..: :::: ::::: :::.::..:::::: . .::.: : NP_009 FPDPNVKYVFRTE-NGGQVMYRVIQVSEGQLDGQTEGTGAIS-----------------G 50 60 70 80 120 130 140 150 160 170 pF1KB7 VDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGD- ::. :. ::::. :.. . .:....:....:::...::: NP_009 Y--------PATQSMTQ--------AVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDG 90 100 110 120 180 190 200 210 220 pF1KB7 -------TTA--VSVQTTD----QSLQAG-GQFYVMMTPQDVLQTGTQRTIAPRTHPYSP .:: :..: .. :. : :::.:::.::.::: :.::.:::::::::: NP_009 AGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSP 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB7 KIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKA : .. :: :::.::::::::::::::::::::::::::::::. ...:.: ::::::::: NP_009 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA 190 200 210 220 230 240 290 300 310 320 330 340 pF1KB7 CDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEG ::::.::::.:.:..: .. ..::.::..::::.:.:::.: ::::::..:.::.: NP_009 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKN 250 260 270 280 290 300 pF1KB7 TRQ NP_009 DSN 310 >>NP_001263302 (OMIM: 191523,602491) upstream stimulator (310 aa) initn: 1000 init1: 749 opt: 756 Z-score: 572.1 bits: 114.1 E(85289): 4e-25 Smith-Waterman score: 1005; 51.8% identity (74.4% similar) in 336 aa overlap (22-340:4-304) 10 20 30 40 50 pF1KB7 MDMLDPGLDPAASATAAAAASHDKGPEAEEG-VELQEGGDGPGAEEQTAVAITSVQQAA- ..: :.::: :..:::. . : :. :.:::.:.:.:: NP_001 MKGQQKTAETEEGTVQIQEGAVATG-EDPTSVAIASIQSAAT 10 20 30 40 60 70 80 90 100 110 pF1KB7 FGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVG : : :..: :::: ::::: :::.::..:::::: . .::.: : NP_001 FPDPNVKYVFRTE-NGGQVMYRVIQVSEGQLDGQTEGTGAIS-----------------G 50 60 70 80 120 130 140 150 160 170 pF1KB7 VDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGD- ::. :. ::::. :.. . .:....:....:::...::: NP_001 Y--------PATQSMTQ--------AVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDG 90 100 110 120 180 190 200 210 220 pF1KB7 -------TTA--VSVQTTD----QSLQAG-GQFYVMMTPQDVLQTGTQRTIAPRTHPYSP .:: :..: .. :. : :::.:::.::.::: :.::.:::::::::: NP_001 AGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSP 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB7 KIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKA : .. :: :::.::::::::::::::::::::::::::::::. ...:.: ::::::::: NP_001 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA 190 200 210 220 230 240 290 300 310 320 330 340 pF1KB7 CDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEG ::::.::::.:.:..: .. ..::.::..::::.:.:::.: ::::::..:.::.: NP_001 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKN 250 260 270 280 290 300 pF1KB7 TRQ NP_001 DSN 310 346 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:56:04 2016 done: Sat Nov 5 01:56:06 2016 Total Scan time: 9.360 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]