FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7925, 192 aa 1>>>pF1KB7925 192 - 192 aa - 192 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3331+/-0.000274; mu= 0.8384+/- 0.017 mean_var=168.1717+/-33.442, 0's: 0 Z-trim(124.3): 14 B-trim: 0 in 0/56 Lambda= 0.098900 statistics sampled from 45570 (45584) to 45570 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.834), E-opt: 0.2 (0.534), width: 16 Scan time: 7.440 The best scores are: opt bits E(85289) NP_149042 (OMIM: 300878) doublesex- and mab-3-rela ( 192) 1301 196.2 2.8e-50 XP_016885214 (OMIM: 300878) PREDICTED: doublesex- ( 192) 1301 196.2 2.8e-50 XP_005262344 (OMIM: 300878) PREDICTED: doublesex- ( 192) 1301 196.2 2.8e-50 XP_005262345 (OMIM: 300878) PREDICTED: doublesex- ( 192) 1301 196.2 2.8e-50 XP_011525517 (OMIM: 614806) PREDICTED: doublesex- ( 244) 293 52.4 6.7e-07 XP_011525516 (OMIM: 614806) PREDICTED: doublesex- ( 244) 293 52.4 6.7e-07 NP_001035373 (OMIM: 614806) doublesex- and mab-3-r ( 367) 293 52.5 9.4e-07 XP_016882618 (OMIM: 614806) PREDICTED: doublesex- ( 372) 293 52.5 9.5e-07 XP_016882615 (OMIM: 614806) PREDICTED: doublesex- ( 418) 235 44.3 0.00032 XP_016882614 (OMIM: 614806) PREDICTED: doublesex- ( 418) 235 44.3 0.00032 XP_016882616 (OMIM: 614806) PREDICTED: doublesex- ( 418) 235 44.3 0.00032 XP_016882617 (OMIM: 614806) PREDICTED: doublesex- ( 418) 235 44.3 0.00032 XP_016882613 (OMIM: 614806) PREDICTED: doublesex- ( 421) 235 44.3 0.00033 XP_016882612 (OMIM: 614806) PREDICTED: doublesex- ( 423) 235 44.3 0.00033 >>NP_149042 (OMIM: 300878) doublesex- and mab-3-related (192 aa) initn: 1301 init1: 1301 opt: 1301 Z-score: 1023.7 bits: 196.2 E(85289): 2.8e-50 Smith-Waterman score: 1301; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:1-192) 10 20 30 40 50 60 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTPVTLEQQLVSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 CTPVTLEQQLVSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 EWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISL 130 140 150 160 170 180 190 pF1KB7 PIGHLGCISLLS :::::::::::: NP_149 PIGHLGCISLLS 190 >>XP_016885214 (OMIM: 300878) PREDICTED: doublesex- and (192 aa) initn: 1301 init1: 1301 opt: 1301 Z-score: 1023.7 bits: 196.2 E(85289): 2.8e-50 Smith-Waterman score: 1301; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:1-192) 10 20 30 40 50 60 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTPVTLEQQLVSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTPVTLEQQLVSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISL 130 140 150 160 170 180 190 pF1KB7 PIGHLGCISLLS :::::::::::: XP_016 PIGHLGCISLLS 190 >>XP_005262344 (OMIM: 300878) PREDICTED: doublesex- and (192 aa) initn: 1301 init1: 1301 opt: 1301 Z-score: 1023.7 bits: 196.2 E(85289): 2.8e-50 Smith-Waterman score: 1301; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:1-192) 10 20 30 40 50 60 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTPVTLEQQLVSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CTPVTLEQQLVSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISL 130 140 150 160 170 180 190 pF1KB7 PIGHLGCISLLS :::::::::::: XP_005 PIGHLGCISLLS 190 >>XP_005262345 (OMIM: 300878) PREDICTED: doublesex- and (192 aa) initn: 1301 init1: 1301 opt: 1301 Z-score: 1023.7 bits: 196.2 E(85289): 2.8e-50 Smith-Waterman score: 1301; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:1-192) 10 20 30 40 50 60 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPLSLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTPVTLEQQLVSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CTPVTLEQQLVSPSGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWQRKLEAAEALLTLRNSAQAPPDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISL 130 140 150 160 170 180 190 pF1KB7 PIGHLGCISLLS :::::::::::: XP_005 PIGHLGCISLLS 190 >>XP_011525517 (OMIM: 614806) PREDICTED: doublesex- and (244 aa) initn: 492 init1: 242 opt: 293 Z-score: 244.9 bits: 52.4 E(85289): 6.7e-07 Smith-Waterman score: 456; 47.4% identity (64.0% similar) in 175 aa overlap (28-192:73-244) 10 20 30 40 50 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPL .: : . : : . :. : : : XP_011 LSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL--QLPTHG 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB7 SLPCTPVTLEQQLVSP-SGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALV . : . . :..: ::.:. :. : ::::::::.: ::: ::::. .: : . XP_011 PFTTCPGS-HPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLART 110 120 130 140 150 120 130 140 150 160 pF1KB7 SAHSEWQRKLEAAEALLTLRNSAQAP---------PDSISLHQPCNPPAPAGDKGFQPPS :. :::: . ::::::. :..:.::: : ::: .::.:::::: .:::: . XP_011 SGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVG 160 170 180 190 200 210 170 180 190 pF1KB7 PSLRPRPASSISLPIGHLGCISLLS : ::: :: :..: ::.:: ::::: XP_011 PCLRPSPAPSVALHIGRLGSISLLS 220 230 240 >>XP_011525516 (OMIM: 614806) PREDICTED: doublesex- and (244 aa) initn: 492 init1: 242 opt: 293 Z-score: 244.9 bits: 52.4 E(85289): 6.7e-07 Smith-Waterman score: 456; 47.4% identity (64.0% similar) in 175 aa overlap (28-192:73-244) 10 20 30 40 50 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPL .: : . : : . :. : : : XP_011 LSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL--QLPTHG 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB7 SLPCTPVTLEQQLVSP-SGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALV . : . . :..: ::.:. :. : ::::::::.: ::: ::::. .: : . XP_011 PFTTCPGS-HPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLART 110 120 130 140 150 120 130 140 150 160 pF1KB7 SAHSEWQRKLEAAEALLTLRNSAQAP---------PDSISLHQPCNPPAPAGDKGFQPPS :. :::: . ::::::. :..:.::: : ::: .::.:::::: .:::: . XP_011 SGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVG 160 170 180 190 200 210 170 180 190 pF1KB7 PSLRPRPASSISLPIGHLGCISLLS : ::: :: :..: ::.:: ::::: XP_011 PCLRPSPAPSVALHIGRLGSISLLS 220 230 240 >>NP_001035373 (OMIM: 614806) doublesex- and mab-3-relat (367 aa) initn: 551 init1: 242 opt: 293 Z-score: 242.2 bits: 52.5 E(85289): 9.4e-07 Smith-Waterman score: 456; 47.4% identity (64.0% similar) in 175 aa overlap (28-192:196-367) 10 20 30 40 50 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPL .: : . : : . :. : : : NP_001 LSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL--QLPTHG 170 180 190 200 210 220 60 70 80 90 100 110 pF1KB7 SLPCTPVTLEQQLVSP-SGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALV . : . . :..: ::.:. :. : ::::::::.: ::: ::::. .: : . NP_001 PFTTCPGS-HPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLART 230 240 250 260 270 280 120 130 140 150 160 pF1KB7 SAHSEWQRKLEAAEALLTLRNSAQAP---------PDSISLHQPCNPPAPAGDKGFQPPS :. :::: . ::::::. :..:.::: : ::: .::.:::::: .:::: . NP_001 SGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVG 290 300 310 320 330 340 170 180 190 pF1KB7 PSLRPRPASSISLPIGHLGCISLLS : ::: :: :..: ::.:: ::::: NP_001 PCLRPSPAPSVALHIGRLGSISLLS 350 360 >>XP_016882618 (OMIM: 614806) PREDICTED: doublesex- and (372 aa) initn: 551 init1: 242 opt: 293 Z-score: 242.1 bits: 52.5 E(85289): 9.5e-07 Smith-Waterman score: 456; 47.4% identity (64.0% similar) in 175 aa overlap (28-192:201-372) 10 20 30 40 50 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPL .: : . : : . :. : : : XP_016 LSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL--QLPTHG 180 190 200 210 220 60 70 80 90 100 110 pF1KB7 SLPCTPVTLEQQLVSP-SGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALV . : . . :..: ::.:. :. : ::::::::.: ::: ::::. .: : . XP_016 PFTTCPGS-HPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLART 230 240 250 260 270 280 120 130 140 150 160 pF1KB7 SAHSEWQRKLEAAEALLTLRNSAQAP---------PDSISLHQPCNPPAPAGDKGFQPPS :. :::: . ::::::. :..:.::: : ::: .::.:::::: .:::: . XP_016 SGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVG 290 300 310 320 330 340 170 180 190 pF1KB7 PSLRPRPASSISLPIGHLGCISLLS : ::: :: :..: ::.:: ::::: XP_016 PCLRPSPAPSVALHIGRLGSISLLS 350 360 370 >>XP_016882615 (OMIM: 614806) PREDICTED: doublesex- and (418 aa) initn: 546 init1: 223 opt: 235 Z-score: 196.7 bits: 44.3 E(85289): 0.00032 Smith-Waterman score: 351; 37.6% identity (50.9% similar) in 226 aa overlap (28-192:196-418) 10 20 30 40 50 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPL .: : . : : . :. : : : XP_016 LSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL--QLPTHG 170 180 190 200 210 220 60 70 80 90 100 pF1KB7 SLPCTPVTLEQQLVSP-SGDPHRAPALPSICSTLILQPCATLDPLLLQPQV--------P . : . . :..: ::.:. :. : ::::::::.: ::: ::::: : XP_016 PFTTCPGS-HPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQVLGKKWDLGP 230 240 250 260 270 280 110 120 pF1KB7 ------------KVSDQ-------------------------------ALVSAHSEWQRK :... : .:. :::: . XP_016 WEEVEPGEGKSRKLKEAGAEEHLEGGQKRGFPVCLSPFPLQASGASCLARTSGPSEWQLQ 290 300 310 320 330 340 130 140 150 160 170 pF1KB7 LEAAEALLTLRNSAQAP---------PDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPAS ::::::. :..:.::: : ::: .::.:::::: .:::: .: ::: :: XP_016 QEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAP 350 360 370 380 390 400 180 190 pF1KB7 SISLPIGHLGCISLLS :..: ::.:: ::::: XP_016 SVALHIGRLGSISLLS 410 >>XP_016882614 (OMIM: 614806) PREDICTED: doublesex- and (418 aa) initn: 546 init1: 223 opt: 235 Z-score: 196.7 bits: 44.3 E(85289): 0.00032 Smith-Waterman score: 351; 37.6% identity (50.9% similar) in 226 aa overlap (28-192:196-418) 10 20 30 40 50 pF1KB7 MAAPPKAPIRVRNLTIRAGALTGKENNMLQPETHIFTAPEEGSSQGALLLGQAPEPL .: : . : : . :. : : : XP_016 LSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL--QLPTHG 170 180 190 200 210 220 60 70 80 90 100 pF1KB7 SLPCTPVTLEQQLVSP-SGDPHRAPALPSICSTLILQPCATLDPLLLQPQV--------P . : . . :..: ::.:. :. : ::::::::.: ::: ::::: : XP_016 PFTTCPGS-HPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQVLGKKWDLGP 230 240 250 260 270 280 110 120 pF1KB7 ------------KVSDQ-------------------------------ALVSAHSEWQRK :... : .:. :::: . XP_016 WEEVEPGEGKSRKLKEAGAEEHLEGGQKRGFPVCLSPFPLQASGASCLARTSGPSEWQLQ 290 300 310 320 330 340 130 140 150 160 170 pF1KB7 LEAAEALLTLRNSAQAP---------PDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPAS ::::::. :..:.::: : ::: .::.:::::: .:::: .: ::: :: XP_016 QEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAP 350 360 370 380 390 400 180 190 pF1KB7 SISLPIGHLGCISLLS :..: ::.:: ::::: XP_016 SVALHIGRLGSISLLS 410 192 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:10:31 2016 done: Sat Nov 5 10:10:32 2016 Total Scan time: 7.440 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]