FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7928, 200 aa 1>>>pF1KB7928 200 - 200 aa - 200 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7106+/-0.000258; mu= 13.8622+/- 0.016 mean_var=89.1171+/-17.620, 0's: 0 Z-trim(121.8): 17 B-trim: 395 in 2/55 Lambda= 0.135861 statistics sampled from 38892 (38911) to 38892 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.456), width: 16 Scan time: 6.100 The best scores are: opt bits E(85289) XP_005262156 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 1327 268.7 4.4e-72 XP_016884824 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 1327 268.7 4.4e-72 XP_005262160 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 1327 268.7 4.4e-72 XP_005262159 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 1327 268.7 4.4e-72 NP_001305399 (OMIM: 300506) TSC22 domain family pr ( 200) 1327 268.7 4.4e-72 XP_011529186 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 1327 268.7 4.4e-72 NP_932174 (OMIM: 300506) TSC22 domain family prote ( 200) 1327 268.7 4.4e-72 XP_005262157 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 1327 268.7 4.4e-72 NP_001305397 (OMIM: 300506) TSC22 domain family pr ( 200) 1327 268.7 4.4e-72 NP_004080 (OMIM: 300506) TSC22 domain family prote ( 134) 591 124.3 8.6e-29 NP_001015881 (OMIM: 300506) TSC22 domain family pr ( 77) 493 104.9 3.4e-23 NP_006013 (OMIM: 607715) TSC22 domain family prote ( 144) 405 87.9 8.6e-18 NP_904358 (OMIM: 607715) TSC22 domain family prote (1073) 404 88.3 4.7e-17 NP_112197 (OMIM: 611914) TSC22 domain family prote ( 395) 344 76.3 7.5e-14 NP_001289972 (OMIM: 611914) TSC22 domain family pr ( 395) 344 76.3 7.5e-14 NP_001230726 (OMIM: 607715) TSC22 domain family pr ( 86) 311 69.3 2e-12 NP_001230727 (OMIM: 607715) TSC22 domain family pr ( 86) 311 69.3 2e-12 >>XP_005262156 (OMIM: 300506) PREDICTED: TSC22 domain fa (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: XP_005 PEEPAPESPQVPEAPGGSAV 190 200 >>XP_016884824 (OMIM: 300506) PREDICTED: TSC22 domain fa (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: XP_016 PEEPAPESPQVPEAPGGSAV 190 200 >>XP_005262160 (OMIM: 300506) PREDICTED: TSC22 domain fa (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: XP_005 PEEPAPESPQVPEAPGGSAV 190 200 >>XP_005262159 (OMIM: 300506) PREDICTED: TSC22 domain fa (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: XP_005 PEEPAPESPQVPEAPGGSAV 190 200 >>NP_001305399 (OMIM: 300506) TSC22 domain family protei (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: NP_001 PEEPAPESPQVPEAPGGSAV 190 200 >>XP_011529186 (OMIM: 300506) PREDICTED: TSC22 domain fa (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: XP_011 PEEPAPESPQVPEAPGGSAV 190 200 >>NP_932174 (OMIM: 300506) TSC22 domain family protein 3 (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_932 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_932 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_932 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: NP_932 PEEPAPESPQVPEAPGGSAV 190 200 >>XP_005262157 (OMIM: 300506) PREDICTED: TSC22 domain fa (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: XP_005 PEEPAPESPQVPEAPGGSAV 190 200 >>NP_001305397 (OMIM: 300506) TSC22 domain family protei (200 aa) initn: 1327 init1: 1327 opt: 1327 Z-score: 1415.1 bits: 268.7 E(85289): 4.4e-72 Smith-Waterman score: 1327; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB7 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQLQEKLVFENL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLS 130 140 150 160 170 180 190 200 pF1KB7 PEEPAPESPQVPEAPGGSAV :::::::::::::::::::: NP_001 PEEPAPESPQVPEAPGGSAV 190 200 >>NP_004080 (OMIM: 300506) TSC22 domain family protein 3 (134 aa) initn: 591 init1: 591 opt: 591 Z-score: 637.9 bits: 124.3 E(85289): 8.6e-29 Smith-Waterman score: 591; 98.9% identity (100.0% similar) in 95 aa overlap (106-200:40-134) 80 90 100 110 120 130 pF1KB7 PVLRDPCYLINEGICNRNIDQTMLSILLFFHSASGASVVAIDNKIEQAMDLVKNHLMYAV .::::::::::::::::::::::::::::: NP_004 MEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVAIDNKIEQAMDLVKNHLMYAV 10 20 30 40 50 60 140 150 160 170 180 190 pF1KB7 REEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPEEPAPESPQVPEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 REEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPEEPAPESPQVPEAP 70 80 90 100 110 120 200 pF1KB7 GGSAV ::::: NP_004 GGSAV 130 200 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:11:08 2016 done: Sat Nov 5 10:11:09 2016 Total Scan time: 6.100 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]