FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7929, 352 aa 1>>>pF1KB7929 352 - 352 aa - 352 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5695+/-0.00036; mu= 16.3582+/- 0.023 mean_var=92.5742+/-18.446, 0's: 0 Z-trim(115.9): 120 B-trim: 211 in 1/55 Lambda= 0.133300 statistics sampled from 26539 (26674) to 26539 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.313), width: 16 Scan time: 8.270 The best scores are: opt bits E(85289) NP_775847 (OMIM: 601332) homeobox protein Mohawk [ ( 352) 2341 460.2 3.1e-129 XP_016871595 (OMIM: 601332) PREDICTED: homeobox pr ( 352) 2341 460.2 3.1e-129 XP_016871594 (OMIM: 601332) PREDICTED: homeobox pr ( 352) 2341 460.2 3.1e-129 NP_001229631 (OMIM: 601332) homeobox protein Mohaw ( 352) 2341 460.2 3.1e-129 XP_016871597 (OMIM: 601332) PREDICTED: homeobox pr ( 291) 1949 384.7 1.3e-106 XP_016871596 (OMIM: 601332) PREDICTED: homeobox pr ( 295) 1874 370.3 2.9e-102 NP_005844 (OMIM: 606195,611174) iroquois-class hom ( 483) 285 64.9 4.1e-10 NP_001239126 (OMIM: 606195,611174) iroquois-class ( 482) 282 64.4 6.2e-10 XP_011512281 (OMIM: 606198) PREDICTED: iroquois-cl ( 471) 278 63.6 1e-09 NP_001127694 (OMIM: 606198) iroquois-class homeodo ( 471) 278 63.6 1e-09 NP_150366 (OMIM: 606198) iroquois-class homeodomai ( 471) 278 63.6 1e-09 XP_011521111 (OMIM: 606195,611174) PREDICTED: iroq ( 413) 277 63.3 1.1e-09 XP_005256194 (OMIM: 606196) PREDICTED: iroquois-cl ( 445) 272 62.4 2.2e-09 NP_077311 (OMIM: 606196) iroquois-class homeodomai ( 446) 272 62.4 2.2e-09 NP_057442 (OMIM: 606199) iroquois-class homeodomai ( 519) 266 61.3 5.5e-09 NP_001265563 (OMIM: 606199) iroquois-class homeodo ( 519) 266 61.3 5.5e-09 NP_001265561 (OMIM: 606199) iroquois-class homeodo ( 519) 266 61.3 5.5e-09 NP_077312 (OMIM: 612985) iroquois-class homeodomai ( 501) 264 60.9 7e-09 XP_005256196 (OMIM: 612985) PREDICTED: iroquois-cl ( 529) 264 60.9 7.3e-09 NP_001265564 (OMIM: 606199) iroquois-class homeodo ( 545) 260 60.2 1.3e-08 NP_001265562 (OMIM: 606199) iroquois-class homeodo ( 545) 260 60.2 1.3e-08 XP_016865334 (OMIM: 606197) PREDICTED: iroquois-cl ( 449) 256 59.3 1.9e-08 NP_077313 (OMIM: 606197) iroquois-class homeodomai ( 480) 256 59.3 2e-08 NP_001273187 (OMIM: 602100) homeobox protein PKNOX ( 319) 207 49.8 9.9e-06 NP_001307623 (OMIM: 602100) homeobox protein PKNOX ( 435) 207 49.9 1.3e-05 NP_004562 (OMIM: 602100) homeobox protein PKNOX1 i ( 436) 207 49.9 1.3e-05 NP_775301 (OMIM: 142946,602630) homeobox protein T ( 252) 193 47.0 5.4e-05 NP_001265615 (OMIM: 142946,602630) homeobox protei ( 252) 193 47.0 5.4e-05 XP_011524037 (OMIM: 142946,602630) PREDICTED: home ( 252) 193 47.0 5.4e-05 NP_775302 (OMIM: 142946,602630) homeobox protein T ( 252) 193 47.0 5.4e-05 NP_775303 (OMIM: 142946,602630) homeobox protein T ( 252) 193 47.0 5.4e-05 XP_016881448 (OMIM: 142946,602630) PREDICTED: home ( 252) 193 47.0 5.4e-05 NP_777480 (OMIM: 142946,602630) homeobox protein T ( 252) 193 47.0 5.4e-05 NP_003235 (OMIM: 142946,602630) homeobox protein T ( 272) 193 47.0 5.7e-05 XP_016881447 (OMIM: 142946,602630) PREDICTED: home ( 272) 193 47.0 5.7e-05 NP_001265613 (OMIM: 142946,602630) homeobox protei ( 272) 193 47.0 5.7e-05 NP_775300 (OMIM: 142946,602630) homeobox protein T ( 272) 193 47.0 5.7e-05 NP_001265611 (OMIM: 142946,602630) homeobox protei ( 275) 193 47.0 5.8e-05 NP_775299 (OMIM: 142946,602630) homeobox protein T ( 286) 193 47.0 5.9e-05 NP_733796 (OMIM: 142946,602630) homeobox protein T ( 401) 193 47.2 7.6e-05 NP_620410 (OMIM: 300411) homeobox protein TGIF2LX ( 241) 187 45.8 0.00012 XP_011541249 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 184 45.4 0.00022 XP_016873600 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 184 45.4 0.00022 XP_006718957 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 184 45.4 0.00022 NP_001186442 (OMIM: 607294) homeobox protein TGIF2 ( 237) 181 44.7 0.00026 NP_001186444 (OMIM: 607294) homeobox protein TGIF2 ( 237) 181 44.7 0.00026 NP_068581 (OMIM: 607294) homeobox protein TGIF2 [H ( 237) 181 44.7 0.00026 NP_001186443 (OMIM: 607294) homeobox protein TGIF2 ( 237) 181 44.7 0.00026 XP_005271700 (OMIM: 613066) PREDICTED: homeobox pr ( 443) 184 45.5 0.00027 XP_016873599 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 184 45.5 0.00029 >>NP_775847 (OMIM: 601332) homeobox protein Mohawk [Homo (352 aa) initn: 2341 init1: 2341 opt: 2341 Z-score: 2441.2 bits: 460.2 E(85289): 3.1e-129 Smith-Waterman score: 2341; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB7 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF 310 320 330 340 350 >>XP_016871595 (OMIM: 601332) PREDICTED: homeobox protei (352 aa) initn: 2341 init1: 2341 opt: 2341 Z-score: 2441.2 bits: 460.2 E(85289): 3.1e-129 Smith-Waterman score: 2341; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB7 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF 310 320 330 340 350 >>XP_016871594 (OMIM: 601332) PREDICTED: homeobox protei (352 aa) initn: 2341 init1: 2341 opt: 2341 Z-score: 2441.2 bits: 460.2 E(85289): 3.1e-129 Smith-Waterman score: 2341; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB7 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF 310 320 330 340 350 >>NP_001229631 (OMIM: 601332) homeobox protein Mohawk [H (352 aa) initn: 2341 init1: 2341 opt: 2341 Z-score: 2441.2 bits: 460.2 E(85289): 3.1e-129 Smith-Waterman score: 2341; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB7 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF 310 320 330 340 350 >>XP_016871597 (OMIM: 601332) PREDICTED: homeobox protei (291 aa) initn: 1949 init1: 1949 opt: 1949 Z-score: 2034.9 bits: 384.7 E(85289): 1.3e-106 Smith-Waterman score: 1949; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291) 10 20 30 40 50 60 pF1KB7 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGESAANRKGPSK ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLENGSNKGES 250 260 270 280 290 310 320 330 340 350 pF1KB7 DDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF >>XP_016871596 (OMIM: 601332) PREDICTED: homeobox protei (295 aa) initn: 1873 init1: 1873 opt: 1874 Z-score: 1956.9 bits: 370.3 E(85289): 2.9e-102 Smith-Waterman score: 1874; 98.6% identity (99.0% similar) in 287 aa overlap (1-286:1-285) 10 20 30 40 50 60 pF1KB7 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTT 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTDTLEN-GSNKGESAANRKGPS ::::::::::::::::::::::::::::::::::::::: .:: :: XP_016 MMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRT--VENLGSLSEDSWDFLK 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 KDDTYWKEINAAMALTNLAQGKDKLQGTTSCIIQKSSHIAEVKTVKVPLVQQF >>NP_005844 (OMIM: 606195,611174) iroquois-class homeodo (483 aa) initn: 268 init1: 244 opt: 285 Z-score: 302.5 bits: 64.9 E(85289): 4.1e-10 Smith-Waterman score: 285; 29.7% identity (56.6% similar) in 219 aa overlap (6-216:45-256) 10 20 30 pF1KB7 MNTIVFNKLSGAVLFE---DGGASERERGGRPYSG :. .:.. : : :. . :. : .. NP_005 LALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAA 20 30 40 50 60 70 40 50 60 70 80 pF1KB7 VLDSPHARPEVGIP-DGPP-LKDNLGLRHRRT--GARQNGGKVRHKRQALQDMARPLKQW . . . :: : : : . .:: . . :. : . ....: .: . :: : NP_005 AAAAFSSY--VGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPA-YRKNATRDATATLKAW 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB7 LYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNK : .:: :::::: :::.::. ..:::.:::.:::::::::: .. ..:. : . .. NP_005 LNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK---KENKMTWTPRNRSEDE 140 150 160 170 180 150 160 170 180 190 200 pF1KB7 YVQGNAERLSVSSDDSCSEDGENPPRTHMNEGGYNTPVHHPVIKSENSVIKAGVRPESRA . : . . . :. . . .. :. . :: . . . .. :: . :. NP_005 EEEENIDLEKNDEDEPQKPEDKGDPEGP-EAGGAEQKAASGCERLQGPPTPAGKETEGSL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 SE-DYVAPPKYKSSLLNRYLNDSLRHVMATNTTMMGKTRQRNHSGSFSSNEFEEELVSPS :. :. :: NP_005 SDSDFKEPPSEGRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAPGPHPAAGEV 250 260 270 280 290 300 >>NP_001239126 (OMIM: 606195,611174) iroquois-class home (482 aa) initn: 268 init1: 244 opt: 282 Z-score: 299.4 bits: 64.4 E(85289): 6.2e-10 Smith-Waterman score: 282; 29.7% identity (56.6% similar) in 219 aa overlap (6-216:45-255) 10 20 30 pF1KB7 MNTIVFNKLSGAVLFE---DGGASERERGGRPYSG :. .:.. : : :. . :. : .. NP_001 LALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAA 20 30 40 50 60 70 40 50 60 70 80 pF1KB7 VLDSPHARPEVGIP-DGPP-LKDNLGLRHRRT--GARQNGGKVRHKRQALQDMARPLKQW . . . :: : : : . .:: . . :. : . ....: .: . :: : NP_001 AAAAFSSY--VGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPA-YRKNATRDATATLKAW 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB7 LYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNK : .:: :::::: :::.::. ..:::.:::.:::::::::: .. ..:. : . .. NP_001 LNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK---KENKMTWTPRNRSEDE 140 150 160 170 180 150 160 170 180 190 200 pF1KB7 YVQGNAERLSVSSDDSCSEDGENPPRTHMNEGGYNTPVHHPVIKSENSVIKAGVRPESRA . : . . . :. . . .. :. :.: . . . .. :: . :. NP_001 EEEENIDLEKNDEDEPQKPEDKGDPEGP--EAGAEQKAASGCERLQGPPTPAGKETEGSL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 SE-DYVAPPKYKSSLLNRYLNDSLRHVMATNTTMMGKTRQRNHSGSFSSNEFEEELVSPS :. :. :: NP_001 SDSDFKEPPSEGRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAPGPHPAAGEV 250 260 270 280 290 300 >>XP_011512281 (OMIM: 606198) PREDICTED: iroquois-class (471 aa) initn: 273 init1: 244 opt: 278 Z-score: 295.4 bits: 63.6 E(85289): 1e-09 Smith-Waterman score: 278; 44.0% identity (69.7% similar) in 109 aa overlap (73-180:117-219) 50 60 70 80 90 100 pF1KB7 VGIPDGPPLKDNLGLRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTE ....: .: . :: :: .:: :::::: : XP_011 YDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGE 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB7 KILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYV-QGNAERLSVSS ::.::. ..:::.:::.:::::::::: .. ..:: : : .. .:.: : :. XP_011 KIMLAIITKMTLTQVSTWFANARRRLK---KENKMTWAPRNKSEDEDEDEGDATR---SK 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB7 DDSCSEDGENPPRTHMNEGGYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSS :.: .. :. . .:: XP_011 DESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKY 210 220 230 240 250 260 >>NP_001127694 (OMIM: 606198) iroquois-class homeodomain (471 aa) initn: 273 init1: 244 opt: 278 Z-score: 295.4 bits: 63.6 E(85289): 1e-09 Smith-Waterman score: 278; 44.0% identity (69.7% similar) in 109 aa overlap (73-180:117-219) 50 60 70 80 90 100 pF1KB7 VGIPDGPPLKDNLGLRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTE ....: .: . :: :: .:: :::::: : NP_001 YDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGE 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB7 KILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYV-QGNAERLSVSS ::.::. ..:::.:::.:::::::::: .. ..:: : : .. .:.: : :. NP_001 KIMLAIITKMTLTQVSTWFANARRRLK---KENKMTWAPRNKSEDEDEDEGDATR---SK 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB7 DDSCSEDGENPPRTHMNEGGYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSS :.: .. :. . .:: NP_001 DESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKY 210 220 230 240 250 260 352 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:39:39 2016 done: Sat Nov 5 14:39:40 2016 Total Scan time: 8.270 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]