FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7934, 215 aa 1>>>pF1KB7934 215 - 215 aa - 215 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8158+/-0.000386; mu= -0.3684+/- 0.024 mean_var=308.6717+/-62.263, 0's: 0 Z-trim(122.6): 74 B-trim: 286 in 1/57 Lambda= 0.073001 statistics sampled from 40865 (40966) to 40865 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.48), width: 16 Scan time: 6.720 The best scores are: opt bits E(85289) NP_001300822 (OMIM: 163905) high mobility group pr ( 215) 1459 166.1 3.9e-41 NP_002119 (OMIM: 163905) high mobility group prote ( 215) 1459 166.1 3.9e-41 NP_001300821 (OMIM: 163905) high mobility group pr ( 215) 1459 166.1 3.9e-41 NP_002120 (OMIM: 163906) high mobility group prote ( 209) 1182 136.9 2.3e-32 NP_001124160 (OMIM: 163906) high mobility group pr ( 209) 1182 136.9 2.3e-32 NP_001124161 (OMIM: 163906) high mobility group pr ( 209) 1182 136.9 2.3e-32 NP_003104 (OMIM: 604585) nuclear autoantigen Sp-10 ( 879) 1048 123.5 1e-27 NP_005333 (OMIM: 300193,300915) high mobility grou ( 200) 1021 119.9 2.9e-27 NP_001288157 (OMIM: 300193,300915) high mobility g ( 200) 1021 119.9 2.9e-27 NP_001288158 (OMIM: 300193,300915) high mobility g ( 200) 1021 119.9 2.9e-27 NP_001288160 (OMIM: 300193,300915) high mobility g ( 220) 1021 120.0 3.1e-27 NP_003137 (OMIM: 604328) FACT complex subunit SSRP ( 709) 294 44.0 0.00073 XP_016873669 (OMIM: 604328) PREDICTED: FACT comple ( 843) 294 44.1 0.00082 NP_001092266 (OMIM: 611163) TOX high mobility grou ( 464) 258 40.0 0.0077 NP_116272 (OMIM: 611163) TOX high mobility group b ( 464) 258 40.0 0.0077 NP_001092267 (OMIM: 611163) TOX high mobility grou ( 506) 258 40.1 0.0081 XP_006723947 (OMIM: 611163) PREDICTED: TOX high mo ( 515) 258 40.1 0.0082 XP_011521304 (OMIM: 611416) PREDICTED: TOX high mo ( 553) 256 39.9 0.01 >>NP_001300822 (OMIM: 163905) high mobility group protei (215 aa) initn: 1459 init1: 1459 opt: 1459 Z-score: 859.4 bits: 166.1 E(85289): 3.9e-41 Smith-Waterman score: 1459; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK 130 140 150 160 170 180 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE ::::::::::::::::::::::::::::::::::: NP_001 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 190 200 210 >>NP_002119 (OMIM: 163905) high mobility group protein B (215 aa) initn: 1459 init1: 1459 opt: 1459 Z-score: 859.4 bits: 166.1 E(85289): 3.9e-41 Smith-Waterman score: 1459; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK 130 140 150 160 170 180 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE ::::::::::::::::::::::::::::::::::: NP_002 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 190 200 210 >>NP_001300821 (OMIM: 163905) high mobility group protei (215 aa) initn: 1459 init1: 1459 opt: 1459 Z-score: 859.4 bits: 166.1 E(85289): 3.9e-41 Smith-Waterman score: 1459; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK 130 140 150 160 170 180 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE ::::::::::::::::::::::::::::::::::: NP_001 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 190 200 210 >>NP_002120 (OMIM: 163906) high mobility group protein B (209 aa) initn: 1182 init1: 1182 opt: 1182 Z-score: 701.9 bits: 136.9 E(85289): 2.3e-32 Smith-Waterman score: 1182; 81.3% identity (94.3% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF ::::::.::::::::::::::::::::::::::.::::.::::::::::::::::::.:: NP_002 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL :::::.:::::.::::.:.::::. : : :::::::::::::::::::.:::::.::::: NP_002 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK ::::.::::::::.. .: ::::::.::::::::::::::::::::: .:.::: . NP_002 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE ::::.: :..::.::.:.:.:.::::::: NP_002 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_001124160 (OMIM: 163906) high mobility group protei (209 aa) initn: 1182 init1: 1182 opt: 1182 Z-score: 701.9 bits: 136.9 E(85289): 2.3e-32 Smith-Waterman score: 1182; 81.3% identity (94.3% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF ::::::.::::::::::::::::::::::::::.::::.::::::::::::::::::.:: NP_001 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL :::::.:::::.::::.:.::::. : : :::::::::::::::::::.:::::.::::: NP_001 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK ::::.::::::::.. .: ::::::.::::::::::::::::::::: .:.::: . NP_001 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE ::::.: :..::.::.:.:.:.::::::: NP_001 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_001124161 (OMIM: 163906) high mobility group protei (209 aa) initn: 1182 init1: 1182 opt: 1182 Z-score: 701.9 bits: 136.9 E(85289): 2.3e-32 Smith-Waterman score: 1182; 81.3% identity (94.3% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF ::::::.::::::::::::::::::::::::::.::::.::::::::::::::::::.:: NP_001 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL :::::.:::::.::::.:.::::. : : :::::::::::::::::::.:::::.::::: NP_001 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK ::::.::::::::.. .: ::::::.::::::::::::::::::::: .:.::: . NP_001 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE ::::.: :..::.::.:.:.:.::::::: NP_001 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_003104 (OMIM: 604585) nuclear autoantigen Sp-100 is (879 aa) initn: 1273 init1: 1037 opt: 1048 Z-score: 618.4 bits: 123.5 E(85289): 1e-27 Smith-Waterman score: 1048; 81.3% identity (89.9% similar) in 198 aa overlap (7-204:682-878) 10 20 30 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASV .: : : .:. : ::::::.::::: NP_003 SKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPC-EEHKKKNPDASV 660 670 680 690 700 710 40 50 60 70 80 90 pF1KB7 NFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPK .:::: ::::: :::. ::::::::::::::::.:::::::::::::: ::::::::::: NP_003 KFSEFLKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKGEKKKKFKDPNAPK 720 730 740 750 760 770 100 110 120 130 140 150 pF1KB7 RPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYE ::: :::::::::::::::::::::: ::.:::. ::::::: ::: ::::::::::::. NP_003 RPPLAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYK 780 790 800 810 820 830 160 170 180 190 200 210 pF1KB7 KDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE ::::::::::::..::: ::::::::::::::::::::..::.:::.. NP_003 KDIAAYRAKGKPNSAKKRVVKAEKSKKKKEEEEDEEDEQEEENEEDDDK 840 850 860 870 >>NP_005333 (OMIM: 300193,300915) high mobility group pr (200 aa) initn: 1247 init1: 536 opt: 1021 Z-score: 610.5 bits: 119.9 E(85289): 2.9e-27 Smith-Waterman score: 1021; 74.3% identity (88.8% similar) in 206 aa overlap (1-206:1-200) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF :.:::::::.::::.:::::::::::::::.:.. :::.::::::::::::::.:::.:: NP_005 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL ..::::::.::.:::: : : :: ::: ::::::::::.:::::::.:::::. .::. NP_005 DEMAKADKVRYDREMKDYGPAKGGKKKK--DPNAPKRPPSGFFLFCSEFRPKIKSTNPGI 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK ::::::::::::::: ..:::: ::::::::::::.: :..::: :.:: : .:. . NP_005 SIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAK-GPAKVAR 120 130 140 150 160 170 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE :: ::::::.::.:::::.:::: NP_005 ---KKVEEEDEEEEEEEEEEEEEEDE 180 190 200 >>NP_001288157 (OMIM: 300193,300915) high mobility group (200 aa) initn: 1247 init1: 536 opt: 1021 Z-score: 610.5 bits: 119.9 E(85289): 2.9e-27 Smith-Waterman score: 1021; 74.3% identity (88.8% similar) in 206 aa overlap (1-206:1-200) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF :.:::::::.::::.:::::::::::::::.:.. :::.::::::::::::::.:::.:: NP_001 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL ..::::::.::.:::: : : :: ::: ::::::::::.:::::::.:::::. .::. NP_001 DEMAKADKVRYDREMKDYGPAKGGKKKK--DPNAPKRPPSGFFLFCSEFRPKIKSTNPGI 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK ::::::::::::::: ..:::: ::::::::::::.: :..::: :.:: : .:. . NP_001 SIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAK-GPAKVAR 120 130 140 150 160 170 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE :: ::::::.::.:::::.:::: NP_001 ---KKVEEEDEEEEEEEEEEEEEEDE 180 190 200 >>NP_001288158 (OMIM: 300193,300915) high mobility group (200 aa) initn: 1247 init1: 536 opt: 1021 Z-score: 610.5 bits: 119.9 E(85289): 2.9e-27 Smith-Waterman score: 1021; 74.3% identity (88.8% similar) in 206 aa overlap (1-206:1-200) 10 20 30 40 50 60 pF1KB7 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF :.:::::::.::::.:::::::::::::::.:.. :::.::::::::::::::.:::.:: NP_001 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL ..::::::.::.:::: : : :: ::: ::::::::::.:::::::.:::::. .::. NP_001 DEMAKADKVRYDREMKDYGPAKGGKKKK--DPNAPKRPPSGFFLFCSEFRPKIKSTNPGI 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK ::::::::::::::: ..:::: ::::::::::::.: :..::: :.:: : .:. . NP_001 SIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAK-GPAKVAR 120 130 140 150 160 170 190 200 210 pF1KB7 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE :: ::::::.::.:::::.:::: NP_001 ---KKVEEEDEEEEEEEEEEEEEEDE 180 190 200 215 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:12:24 2016 done: Sat Nov 5 10:12:25 2016 Total Scan time: 6.720 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]