FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7935, 371 aa 1>>>pF1KB7935 371 - 371 aa - 371 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7431+/-0.00081; mu= 11.3041+/- 0.049 mean_var=124.2848+/-24.646, 0's: 0 Z-trim(112.0): 73 B-trim: 0 in 0/50 Lambda= 0.115044 statistics sampled from 12770 (12844) to 12770 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.395), width: 16 Scan time: 3.160 The best scores are: opt bits E(32554) CCDS1419.1 ELF3 gene_id:1999|Hs108|chr1 ( 371) 2547 433.5 1.4e-121 CCDS55753.1 EHF gene_id:26298|Hs108|chr11 ( 277) 584 107.6 1.4e-23 CCDS7894.1 EHF gene_id:26298|Hs108|chr11 ( 300) 581 107.1 2.1e-23 CCDS55752.1 EHF gene_id:26298|Hs108|chr11 ( 322) 581 107.1 2.2e-23 CCDS58129.1 ELF5 gene_id:2001|Hs108|chr11 ( 160) 465 87.7 7.9e-18 CCDS73273.1 ELF5 gene_id:2001|Hs108|chr11 ( 187) 465 87.7 9e-18 CCDS7893.1 ELF5 gene_id:2001|Hs108|chr11 ( 255) 465 87.8 1.1e-17 CCDS7892.1 ELF5 gene_id:2001|Hs108|chr11 ( 265) 465 87.8 1.2e-17 >>CCDS1419.1 ELF3 gene_id:1999|Hs108|chr1 (371 aa) initn: 2547 init1: 2547 opt: 2547 Z-score: 2296.0 bits: 433.5 E(32554): 1.4e-121 Smith-Waterman score: 2547; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371) 10 20 30 40 50 60 pF1KB7 MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSG 310 320 330 340 350 360 370 pF1KB7 WKEEEVLQSRN ::::::::::: CCDS14 WKEEEVLQSRN 370 >>CCDS55753.1 EHF gene_id:26298|Hs108|chr11 (277 aa) initn: 720 init1: 581 opt: 584 Z-score: 536.9 bits: 107.6 E(32554): 1.4e-23 Smith-Waterman score: 644; 39.6% identity (59.7% similar) in 313 aa overlap (53-365:36-276) 30 40 50 60 70 80 pF1KB7 DSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWLGEQPQFWSKTQVLDWISYQVEK : ..: .::.:.: :: .:... .. CCDS55 GGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDT 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB7 NKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQLHAQLRDLTSSSSDELSWIIEL :. ::. : :.. :..: ::. .:.:. . : :. :...:. .:.: CCDS55 NQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQ--------HLKW---- 70 80 90 100 110 150 160 170 180 190 200 pF1KB7 LEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYHPGSCGAGAPSPGSSDVSTAGTG .:: .: .. .. . . ... : .: CCDS55 -----------------------------NGQCSSDLFQSTHNVIVKTE-QTEPSIMNTW 120 130 140 210 220 230 240 250 260 pF1KB7 ASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDPKHGKRKRGRPRKLSKEYWDCLE ... . . :: : .: : : :. :: : : : CCDS55 KDENYLYDTNYGSTVAESP-DMK----------KEQDP---------PAK-------C-- 150 160 170 270 280 290 300 310 320 pF1KB7 GKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNS . .:: ::::::::::::::..:. : ::.:::.: ::::.::.:::::::::.::.:: CCDS55 -HTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNS 180 190 200 210 220 230 330 340 350 360 370 pF1KB7 NMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVLQSRN .::::::::::::::::::::::::::::::::::. ::.:.: CCDS55 SMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN 240 250 260 270 >>CCDS7894.1 EHF gene_id:26298|Hs108|chr11 (300 aa) initn: 720 init1: 581 opt: 581 Z-score: 533.8 bits: 107.1 E(32554): 2.1e-23 Smith-Waterman score: 671; 40.2% identity (61.1% similar) in 316 aa overlap (53-365:36-299) 30 40 50 60 70 80 pF1KB7 DSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWLGEQPQFWSKTQVLDWISYQVEK : ..: .::.:.: :: .:... .. CCDS78 GGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDT 10 20 30 40 50 60 90 100 110 120 130 pF1KB7 NKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQLHAQLRDLT---SSSSDELSWI :. ::. : :.. :..: ::. .:.:. . : :. :...:. : . ::: .. CCDS78 NQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQST 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB7 IELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYHPGSCGAGAPSPGSSDVSTA ... : : .:. ... .. . . . :. . :. : CCDS78 HNVIVKT-----EQTEPS-----------IMNTWKDENYLYDTNYGSTVDLLDSKTFCRA 130 140 150 160 200 210 220 230 240 250 pF1KB7 GTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDPKHGKRKRGRPRKLSKEYWD . . .:: : .: : : :. :: : : CCDS78 QISMTTTSHLP------VAESP-DMK----------KEQDP---------PAK------- 170 180 190 260 270 280 290 300 310 pF1KB7 CLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKK : . .:: ::::::::::::::..:. : ::.:::.: ::::.::.:::::::::.:: CCDS78 C---HTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKK 200 210 220 230 240 250 320 330 340 350 360 370 pF1KB7 KNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVLQSRN .::.::::::::::::::::::::::::::::::::::. ::.:.: CCDS78 NNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN 260 270 280 290 300 >>CCDS55752.1 EHF gene_id:26298|Hs108|chr11 (322 aa) initn: 720 init1: 581 opt: 581 Z-score: 533.3 bits: 107.1 E(32554): 2.2e-23 Smith-Waterman score: 671; 40.2% identity (61.1% similar) in 316 aa overlap (53-365:58-321) 30 40 50 60 70 80 pF1KB7 DSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWLGEQPQFWSKTQVLDWISYQVEK : ..: .::.:.: :: .:... .. CCDS55 GGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDT 30 40 50 60 70 80 90 100 110 120 130 pF1KB7 NKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQLHAQLRDLT---SSSSDELSWI :. ::. : :.. :..: ::. .:.:. . : :. :...:. : . ::: .. CCDS55 NQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQST 90 100 110 120 130 140 140 150 160 170 180 190 pF1KB7 IELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYHPGSCGAGAPSPGSSDVSTA ... : : .:. ... .. . . . :. . :. : CCDS55 HNVIVKT-----EQTEPS-----------IMNTWKDENYLYDTNYGSTVDLLDSKTFCRA 150 160 170 180 190 200 210 220 230 240 250 pF1KB7 GTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDPKHGKRKRGRPRKLSKEYWD . . .:: : .: : : :. :: : : CCDS55 QISMTTTSHLP------VAESP-DMK----------KEQDP---------PAK------- 200 210 260 270 280 290 300 310 pF1KB7 CLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKK : . .:: ::::::::::::::..:. : ::.:::.: ::::.::.:::::::::.:: CCDS55 C---HTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKK 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB7 KNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVLQSRN .::.::::::::::::::::::::::::::::::::::. ::.:.: CCDS55 NNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN 280 290 300 310 320 >>CCDS58129.1 ELF5 gene_id:2001|Hs108|chr11 (160 aa) initn: 459 init1: 368 opt: 465 Z-score: 433.5 bits: 87.7 E(32554): 7.9e-18 Smith-Waterman score: 465; 58.3% identity (87.0% similar) in 108 aa overlap (259-366:56-160) 230 240 250 260 270 280 pF1KB7 SDGFRDCKKGDPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPEL :: ..:. . ...:::::.::.:. :: CCDS58 LFSNEEYYPAFEHQTDADSNCLKTSGIKSQDC--HSHSRTSLQSSHLWEFVRDLLLSPEE 30 40 50 60 70 80 290 300 310 320 330 340 pF1KB7 NEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGR : :...::.:..:.:. ..:::.:..:::.:::. :::::::::.::::: :::::: : CCDS58 NCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD-R 90 100 110 120 130 140 350 360 370 pF1KB7 RLVYKFGKNSSGWKEEEVLQSRN :::::::::. ::.:... CCDS58 RLVYKFGKNAHGWQEDKL 150 160 >>CCDS73273.1 ELF5 gene_id:2001|Hs108|chr11 (187 aa) initn: 459 init1: 368 opt: 465 Z-score: 432.6 bits: 87.7 E(32554): 9e-18 Smith-Waterman score: 465; 58.3% identity (87.0% similar) in 108 aa overlap (259-366:83-187) 230 240 250 260 270 280 pF1KB7 SDGFRDCKKGDPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPEL :: ..:. . ...:::::.::.:. :: CCDS73 SFFNDAEESKATIKDYADSNCLKTSGIKSQDC--HSHSRTSLQSSHLWEFVRDLLLSPEE 60 70 80 90 100 110 290 300 310 320 330 340 pF1KB7 NEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGR : :...::.:..:.:. ..:::.:..:::.:::. :::::::::.::::: :::::: : CCDS73 NCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD-R 120 130 140 150 160 350 360 370 pF1KB7 RLVYKFGKNSSGWKEEEVLQSRN :::::::::. ::.:... CCDS73 RLVYKFGKNAHGWQEDKL 170 180 >>CCDS7893.1 ELF5 gene_id:2001|Hs108|chr11 (255 aa) initn: 481 init1: 368 opt: 465 Z-score: 430.7 bits: 87.8 E(32554): 1.1e-17 Smith-Waterman score: 465; 58.3% identity (87.0% similar) in 108 aa overlap (259-366:151-255) 230 240 250 260 270 280 pF1KB7 SDGFRDCKKGDPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPEL :: ..:. . ...:::::.::.:. :: CCDS78 SFFNDAEESKATIKDYADSNCLKTSGIKSQDC--HSHSRTSLQSSHLWEFVRDLLLSPEE 130 140 150 160 170 290 300 310 320 330 340 pF1KB7 NEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGR : :...::.:..:.:. ..:::.:..:::.:::. :::::::::.::::: :::::: : CCDS78 NCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD-R 180 190 200 210 220 230 350 360 370 pF1KB7 RLVYKFGKNSSGWKEEEVLQSRN :::::::::. ::.:... CCDS78 RLVYKFGKNAHGWQEDKL 240 250 >>CCDS7892.1 ELF5 gene_id:2001|Hs108|chr11 (265 aa) initn: 481 init1: 368 opt: 465 Z-score: 430.5 bits: 87.8 E(32554): 1.2e-17 Smith-Waterman score: 465; 58.3% identity (87.0% similar) in 108 aa overlap (259-366:161-265) 230 240 250 260 270 280 pF1KB7 SDGFRDCKKGDPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPEL :: ..:. . ...:::::.::.:. :: CCDS78 SFFNDAEESKATIKDYADSNCLKTSGIKSQDC--HSHSRTSLQSSHLWEFVRDLLLSPEE 140 150 160 170 180 290 300 310 320 330 340 pF1KB7 NEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGR : :...::.:..:.:. ..:::.:..:::.:::. :::::::::.::::: :::::: : CCDS78 NCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD-R 190 200 210 220 230 240 350 360 370 pF1KB7 RLVYKFGKNSSGWKEEEVLQSRN :::::::::. ::.:... CCDS78 RLVYKFGKNAHGWQEDKL 250 260 371 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:40:14 2016 done: Sat Nov 5 14:40:14 2016 Total Scan time: 3.160 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]