Result of FASTA (omim) for
pF1KB7939
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7939, 342 aa
1>>>pF1KB7939 342 - 342 aa - 342 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5209+/-0.00034; mu= 11.6383+/- 0.021
mean_var=153.3124+/-34.550, 0's: 0 Z-trim(118.9): 81 B-trim: 1910 in 1/49
Lambda= 0.103582
statistics sampled from 32183 (32266) to 32183 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.378), width: 16
Scan time: 5.450
The best scores are: opt bits E(85289)
XP_011535228 (OMIM: 611299) PREDICTED: G2/M phase- ( 667) 798 131.2 6.2e-30
NP_060239 (OMIM: 611299) G2/M phase-specific E3 ub ( 706) 659 110.5 1.1e-23
XP_011535227 (OMIM: 611299) PREDICTED: G2/M phase- ( 706) 659 110.5 1.1e-23
NP_001295026 (OMIM: 611299) G2/M phase-specific E3 ( 660) 563 96.1 2.3e-19
NP_115711 (OMIM: 300414,301900) PHD finger protein ( 312) 239 47.3 5.2e-05
NP_115834 (OMIM: 300414,301900) PHD finger protein ( 365) 237 47.1 7.1e-05
NP_001015877 (OMIM: 300414,301900) PHD finger prot ( 365) 237 47.1 7.1e-05
>>XP_011535228 (OMIM: 611299) PREDICTED: G2/M phase-spec (667 aa)
initn: 732 init1: 382 opt: 798 Z-score: 658.4 bits: 131.2 E(85289): 6.2e-30
Smith-Waterman score: 798; 41.1% identity (62.4% similar) in 314 aa overlap (22-326:1-308)
10 20 30 40 50
pF1KB7 MKTVKEKKECQRLRKSAKTRRVTQRKP--SSGPVCWLCLREPGDPEKLGEFLQKD--NIS
... :: :.. .: .: .. :.: :: :. :..
XP_011 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLT
10 20 30
60 70 80 90 100 110
pF1KB7 VHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCL
:::.::..:: . :::. ..: .::: :::.::. :::. : ::::.::.:.: .:
XP_011 VHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCK
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB7 RNFHLPCGQERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEE-SCILCCEDLSQQSVENI
:..:.::: .: :. :: :.. ::: :::.: : .. : : .: : . ::
XP_011 RSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNI
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 -QSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRRWCLILC
.::::..: .:: :.: : ... ::.: ::: : .::::::::::. .: . :
XP_011 LRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPENKWEIKRC
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 ATCGSHGTHRDCSSLRSNSKKWECEECSPAAATDYIPENSGDIPCCSSTFHPEEHFC--R
::: ::: :::::: ..::: :: : :::.. .. :. .
XP_011 QCCGSSGTHLACSSLRSWEQNWECLECRG------IIYNSGEFQKAKKHVLPNSNNVGIT
220 230 240 250 260 270
300 310 320 330 340
pF1KB7 DNTLEEN-PGLSWTDWPEPSLLEKPESSRGRRSYSWRSKGVRITNSCKKSK
: :::. : : . : ..:. ::. :
XP_011 DCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKKTKRLYINKANIW
280 290 300 310 320 330
XP_011 NSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENSSLFEGSLSK
340 350 360 370 380 390
>>NP_060239 (OMIM: 611299) G2/M phase-specific E3 ubiqui (706 aa)
initn: 580 init1: 382 opt: 659 Z-score: 545.9 bits: 110.5 E(85289): 1.1e-23
Smith-Waterman score: 716; 36.8% identity (55.5% similar) in 353 aa overlap (22-326:1-347)
10 20 30 40 50
pF1KB7 MKTVKEKKECQRLRKSAKTRRVTQRKP--SSGPVCWLCLREPGDPEKLGEFLQKD--NIS
... :: :.. .: .: .. :.: :: :. :..
NP_060 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLT
10 20 30
60 70 80 90 100 110
pF1KB7 VHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCL
:::.::..:: . :::. ..: .::: :::.::. :::. : ::::.::.:.: .:
NP_060 VHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCK
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB7 RNFHLPCGQERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEE-SCILCCEDLSQQSVENI
:..:.::: .: :. :: :.. ::: :::.: : .. : : .: : . ::
NP_060 RSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNI
100 110 120 130 140 150
180 190 200 210 220
pF1KB7 -QSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIP---------
.::::..: .:: :.: : ... ::.: ::: : .::::::::::
NP_060 LRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELE
160 170 180 190 200 210
230 240 250
pF1KB7 ------------------------------DRRWCLILCATCGSHGTHRDCSSLRSNSKK
: .: . : ::: ::: :::::: ..
NP_060 ENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQN
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB7 WECEECSPAAATDYIPENSGDIPCCSSTFHPEEHFC--RDNTLEEN-PGLSWTDWPEPSL
::: :: : :::.. .. :. . : :::. : : . :
NP_060 WECLECRG------IIYNSGEFQKAKKHVLPNSNNVGITDCLLEESSPKLPRQSPGSQSK
280 290 300 310 320 330
320 330 340
pF1KB7 LEKPESSRGRRSYSWRSKGVRITNSCKKSK
..:. ::. :
NP_060 DLLRQGSKFRRNVSTLLIELGFQIKKKTKRLYINKANIWNSALDAFRNRNFNPSYAIEVA
340 350 360 370 380 390
>>XP_011535227 (OMIM: 611299) PREDICTED: G2/M phase-spec (706 aa)
initn: 580 init1: 382 opt: 659 Z-score: 545.9 bits: 110.5 E(85289): 1.1e-23
Smith-Waterman score: 716; 36.8% identity (55.5% similar) in 353 aa overlap (22-326:1-347)
10 20 30 40 50
pF1KB7 MKTVKEKKECQRLRKSAKTRRVTQRKP--SSGPVCWLCLREPGDPEKLGEFLQKD--NIS
... :: :.. .: .: .. :.: :: :. :..
XP_011 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLT
10 20 30
60 70 80 90 100 110
pF1KB7 VHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCL
:::.::..:: . :::. ..: .::: :::.::. :::. : ::::.::.:.: .:
XP_011 VHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCK
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB7 RNFHLPCGQERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEE-SCILCCEDLSQQSVENI
:..:.::: .: :. :: :.. ::: :::.: : .. : : .: : . ::
XP_011 RSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNI
100 110 120 130 140 150
180 190 200 210 220
pF1KB7 -QSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIP---------
.::::..: .:: :.: : ... ::.: ::: : .::::::::::
XP_011 LRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELE
160 170 180 190 200 210
230 240 250
pF1KB7 ------------------------------DRRWCLILCATCGSHGTHRDCSSLRSNSKK
: .: . : ::: ::: :::::: ..
XP_011 ENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQN
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB7 WECEECSPAAATDYIPENSGDIPCCSSTFHPEEHFC--RDNTLEEN-PGLSWTDWPEPSL
::: :: : :::.. .. :. . : :::. : : . :
XP_011 WECLECRG------IIYNSGEFQKAKKHVLPNSNNVGITDCLLEESSPKLPRQSPGSQSK
280 290 300 310 320 330
320 330 340
pF1KB7 LEKPESSRGRRSYSWRSKGVRITNSCKKSK
..:. ::. :
XP_011 DLLRQGSKFRRNVSTLLIELGFQIKKKTKRLYINKANIWNSALDAFRNRNFNPSYAIEVA
340 350 360 370 380 390
>>NP_001295026 (OMIM: 611299) G2/M phase-specific E3 ubi (660 aa)
initn: 530 init1: 332 opt: 563 Z-score: 468.7 bits: 96.1 E(85289): 2.3e-19
Smith-Waterman score: 620; 37.1% identity (53.7% similar) in 307 aa overlap (64-326:1-301)
40 50 60 70 80 90
pF1KB7 WLCLREPGDPEKLGEFLQKDNISVHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARA
.:: . :::. ..: .::: :::.::. ::
NP_001 MSSGIWQRGKEEEGVYGFLIEDIRKEVNRA
10 20 30
100 110 120 130 140 150
pF1KB7 SRKICFVCKKKGAAINCQKDQCLRNFHLPCGQERGCLSQFFGEYKSFCDKHRPTQNIQHG
:. : ::::.::.:.: .: :..:.::: .: :. :: :.. ::: :::.: : .
NP_001 SKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSN
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB7 HVGEE-SCILCCEDLSQQSVENI-QSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRK
. : : .: : . :: .::::..: .:: :.: : ... ::.: :::
NP_001 NYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSD
100 110 120 130 140 150
220 230
pF1KB7 EFPQEMLRMGIHIP---------------------------------------DRRWCLI
: .:::::::::: : .: .
NP_001 IFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIK
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 LCATCGSHGTHRDCSSLRSNSKKWECEECSPAAATDYIPENSGDIPCCSSTFHPEEHFC-
: ::: ::: :::::: ..::: :: : :::.. .. :. .
NP_001 RCQCCGSSGTHLACSSLRSWEQNWECLECRG------IIYNSGEFQKAKKHVLPNSNNVG
220 230 240 250 260
300 310 320 330 340
pF1KB7 -RDNTLEEN-PGLSWTDWPEPSLLEKPESSRGRRSYSWRSKGVRITNSCKKSK
: :::. : : . : ..:. ::. :
NP_001 ITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKKTKRLYINKAN
270 280 290 300 310 320
NP_001 IWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENSSLFEGSL
330 340 350 360 370 380
>>NP_115711 (OMIM: 300414,301900) PHD finger protein 6 i (312 aa)
initn: 163 init1: 116 opt: 239 Z-score: 211.0 bits: 47.3 E(85289): 5.2e-05
Smith-Waterman score: 239; 32.2% identity (60.3% similar) in 146 aa overlap (22-159:5-146)
10 20 30 40 50
pF1KB7 MKTVKEKKECQRLRKSAKTRRVTQRK-PSSGPVCWLCLREPGDPEKLGEFLQKDN--ISV
: :.: :. : .: . : : :..: ..: ...
NP_115 MSSSVEQKKGPTRQRKCGFC-KSNRDKE-CGQLLISENQKVAA
10 20 30 40
60 70 80 90 100 110
pF1KB7 HYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLR
:. :...:: : . ..:... :: ::..:: :... .: .:. ::.:.:. : :
NP_115 HHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 NFHLPCG-----QERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEESCILCCEDLSQQSV
..: :. : : :: : : .: ::. : . ... :::
NP_115 TYHYHCALHDKAQIREKPSQ--GIYMVYCRKHKKTAHNSEAADLEESFNEHELEPSSPKS
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 ENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRRWCLI
NP_115 KKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVG
160 170 180 190 200 210
>>NP_115834 (OMIM: 300414,301900) PHD finger protein 6 i (365 aa)
initn: 137 init1: 116 opt: 237 Z-score: 208.5 bits: 47.1 E(85289): 7.1e-05
Smith-Waterman score: 237; 32.2% identity (61.0% similar) in 146 aa overlap (22-159:5-145)
10 20 30 40 50
pF1KB7 MKTVKEKKECQRLRKSAKTRRVTQRK-PSSGPVCWLCLREPGDPEKLGEFLQKDN--ISV
: :.: :. : .: . : : :..: ..: ...
NP_115 MSSSVEQKKGPTRQRKCGFC-KSNRDKE-CGQLLISENQKVAA
10 20 30 40
60 70 80 90 100 110
pF1KB7 HYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLR
:. :...:: : . ..:... :: ::..:: :... .: .:. ::.:.:. : :
NP_115 HHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 NFHLPCG-----QERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEESCILCCEDLSQQSV
..: :. : : :: : : .: ::. : . ... . :::
NP_115 TYHYHCALHDKAQIREKPSQ--GIYMVYCRKHKKTAHNSEADL-EESFNEHELEPSSPKS
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 ENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRRWCLI
NP_115 KKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVG
160 170 180 190 200 210
>>NP_001015877 (OMIM: 300414,301900) PHD finger protein (365 aa)
initn: 137 init1: 116 opt: 237 Z-score: 208.5 bits: 47.1 E(85289): 7.1e-05
Smith-Waterman score: 237; 32.2% identity (61.0% similar) in 146 aa overlap (22-159:5-145)
10 20 30 40 50
pF1KB7 MKTVKEKKECQRLRKSAKTRRVTQRK-PSSGPVCWLCLREPGDPEKLGEFLQKDN--ISV
: :.: :. : .: . : : :..: ..: ...
NP_001 MSSSVEQKKGPTRQRKCGFC-KSNRDKE-CGQLLISENQKVAA
10 20 30 40
60 70 80 90 100 110
pF1KB7 HYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLR
:. :...:: : . ..:... :: ::..:: :... .: .:. ::.:.:. : :
NP_001 HHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 NFHLPCG-----QERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEESCILCCEDLSQQSV
..: :. : : :: : : .: ::. : . ... . :::
NP_001 TYHYHCALHDKAQIREKPSQ--GIYMVYCRKHKKTAHNSEADL-EESFNEHELEPSSPKS
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 ENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRRWCLI
NP_001 KKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVG
160 170 180 190 200 210
342 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:41:19 2016 done: Sat Nov 5 14:41:20 2016
Total Scan time: 5.450 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]