FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7940, 240 aa 1>>>pF1KB7940 240 - 240 aa - 240 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5177+/-0.000794; mu= 10.3754+/- 0.048 mean_var=120.8391+/-23.727, 0's: 0 Z-trim(111.6): 48 B-trim: 187 in 2/51 Lambda= 0.116673 statistics sampled from 12486 (12532) to 12486 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.385), width: 16 Scan time: 1.800 The best scores are: opt bits E(32554) CCDS33425.1 ING5 gene_id:84289|Hs108|chr2 ( 240) 1656 289.0 1.9e-78 CCDS82586.1 ING5 gene_id:84289|Hs108|chr2 ( 226) 1541 269.6 1.2e-72 CCDS44814.1 ING4 gene_id:51147|Hs108|chr12 ( 246) 1165 206.4 1.4e-53 CCDS44815.1 ING4 gene_id:51147|Hs108|chr12 ( 245) 1162 205.9 2e-53 CCDS82585.1 ING5 gene_id:84289|Hs108|chr2 ( 254) 982 175.6 2.8e-44 CCDS44816.1 ING4 gene_id:51147|Hs108|chr12 ( 179) 711 129.8 1.1e-30 CCDS44813.1 ING4 gene_id:51147|Hs108|chr12 ( 249) 711 130.0 1.5e-30 CCDS8555.1 ING4 gene_id:51147|Hs108|chr12 ( 248) 694 127.1 1.1e-29 CCDS3833.1 ING2 gene_id:3622|Hs108|chr4 ( 280) 579 107.8 7.9e-24 CCDS44812.1 ING4 gene_id:51147|Hs108|chr12 ( 225) 567 105.7 2.7e-23 CCDS9516.1 ING1 gene_id:3621|Hs108|chr13 ( 279) 421 81.2 8e-16 CCDS9517.1 ING1 gene_id:3621|Hs108|chr13 ( 422) 423 81.7 8.6e-16 CCDS9515.1 ING1 gene_id:3621|Hs108|chr13 ( 235) 418 80.6 9.9e-16 CCDS9518.1 ING1 gene_id:3621|Hs108|chr13 ( 210) 416 80.2 1.1e-15 CCDS5778.1 ING3 gene_id:54556|Hs108|chr7 ( 418) 372 73.1 3.3e-13 >>CCDS33425.1 ING5 gene_id:84289|Hs108|chr2 (240 aa) initn: 1656 init1: 1656 opt: 1656 Z-score: 1522.0 bits: 289.0 E(32554): 1.9e-78 Smith-Waterman score: 1656; 100.0% identity (100.0% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK 190 200 210 220 230 240 >>CCDS82586.1 ING5 gene_id:84289|Hs108|chr2 (226 aa) initn: 1541 init1: 1541 opt: 1541 Z-score: 1417.7 bits: 269.6 E(32554): 1.2e-72 Smith-Waterman score: 1541; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK :::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGK 190 200 210 220 >>CCDS44814.1 ING4 gene_id:51147|Hs108|chr12 (246 aa) initn: 1106 init1: 607 opt: 1165 Z-score: 1075.2 bits: 206.4 E(32554): 1.4e-53 Smith-Waterman score: 1165; 69.9% identity (88.8% similar) in 249 aa overlap (1-239:1-246) 10 20 30 40 50 60 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ ::..:::::::::::::: ::::::::::.::::::: ::::: ::.::.:....:: .. CCDS44 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD .. :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:.:: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPK--KKKHK---GGSEF---TDTILS ..::.. :.:: ::::...:.:.. ..:.:..:: .:: : . :. . :. : CCDS44 YDSSSS---KEGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP ::::::::::::::::::::::::::::::::::::: ::::::::: :::::.:::::: CCDS44 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 180 190 200 210 220 230 240 pF1KB7 RCVQEKRKKK :: ::..:: CCDS44 RCSQERKKK 240 >>CCDS44815.1 ING4 gene_id:51147|Hs108|chr12 (245 aa) initn: 1085 init1: 586 opt: 1162 Z-score: 1072.5 bits: 205.9 E(32554): 2e-53 Smith-Waterman score: 1162; 69.9% identity (88.4% similar) in 249 aa overlap (1-239:1-245) 10 20 30 40 50 60 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ ::..:::::::::::::: ::::::::::.::::::: ::::: ::.::.:....:: .. CCDS44 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD .. :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:.:: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPK--KKKHK---GGSEF---TDTILS ..::.. ::: ::::...:.:.. ..:.:..:: .:: : . :. . :. : CCDS44 YDSSSS----KGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP ::::::::::::::::::::::::::::::::::::: ::::::::: :::::.:::::: CCDS44 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 180 190 200 210 220 230 240 pF1KB7 RCVQEKRKKK :: ::..:: CCDS44 RCSQERKKK 240 >>CCDS82585.1 ING5 gene_id:84289|Hs108|chr2 (254 aa) initn: 1016 init1: 971 opt: 982 Z-score: 908.5 bits: 175.6 E(32554): 2.8e-44 Smith-Waterman score: 982; 89.0% identity (93.6% similar) in 173 aa overlap (11-183:13-181) 10 20 30 40 50 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSP : .::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MGARVTPRDSGGLIGIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 DQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 DFESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLD :::::::::::::::::::::::::::::::::::::::::::. ...::. :. . CCDS82 DFESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGG---NSVLSL-PAPSCS 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 MPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRK : : CCDS82 EPEGPVPTVPFLRESGTPPGLFLTQCCFSRWQCCSCPIARRRDRLVRPALKLGSDVQGAK 180 190 200 210 220 230 >>CCDS44816.1 ING4 gene_id:51147|Hs108|chr12 (179 aa) initn: 599 init1: 580 opt: 711 Z-score: 664.0 bits: 129.8 E(32554): 1.1e-30 Smith-Waterman score: 711; 67.1% identity (92.5% similar) in 161 aa overlap (1-159:1-161) 10 20 30 40 50 60 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ ::..:::::::::::::: ::::::::::.::::::: ::::: ::.::.:....:: .. CCDS44 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD .. :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:.:: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLD ..::...: :::: ::::...:.:.. ..:.:..:: ..: CCDS44 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSILPVWG 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 MPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRK >>CCDS44813.1 ING4 gene_id:51147|Hs108|chr12 (249 aa) initn: 1098 init1: 580 opt: 711 Z-score: 662.1 bits: 130.0 E(32554): 1.5e-30 Smith-Waterman score: 1194; 70.7% identity (89.6% similar) in 249 aa overlap (1-239:1-249) 10 20 30 40 50 60 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ ::..:::::::::::::: ::::::::::.::::::: ::::: ::.::.:....:: .. CCDS44 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD .. :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:.:: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPK--KKKHK---GGSEF---TDTILS ..::...: :::: ::::...:.:.. ..:.:..:: .:: : . :. . :. : CCDS44 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP ::::::::::::::::::::::::::::::::::::: ::::::::: :::::.:::::: CCDS44 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 190 200 210 220 230 240 240 pF1KB7 RCVQEKRKKK :: ::..:: CCDS44 RCSQERKKK >>CCDS8555.1 ING4 gene_id:51147|Hs108|chr12 (248 aa) initn: 1138 init1: 639 opt: 694 Z-score: 646.6 bits: 127.1 E(32554): 1.1e-29 Smith-Waterman score: 1177; 70.3% identity (89.6% similar) in 249 aa overlap (1-239:1-248) 10 20 30 40 50 60 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ ::..:::::::::::::: ::::::::::.::::::: ::::: ::.::.:....:: .. CCDS85 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD .. :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:.:: CCDS85 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPK--KKKHK---GGSEF---TDTILS ..::...: ::.: ::::...:.:.. ..:.:..:: .:: : . :. . :. : CCDS85 YDSSSSKG-KKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP ::::::::::::::::::::::::::::::::::::: ::::::::: :::::.:::::: CCDS85 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 180 190 200 210 220 230 240 pF1KB7 RCVQEKRKKK :: ::..:: CCDS85 RCSQERKKK 240 >>CCDS3833.1 ING2 gene_id:3622|Hs108|chr4 (280 aa) initn: 499 init1: 368 opt: 579 Z-score: 541.3 bits: 107.8 E(32554): 7.9e-24 Smith-Waterman score: 579; 37.8% identity (69.7% similar) in 241 aa overlap (6-238:27-264) 10 20 30 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKK :.. ::. .:.:: ..::: ...::::.. .. CCDS38 MLGQQQQQLYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDNKYQETL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 AEIDILAAEYISTVKTLSPDQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRR ::: . .: . :. .:...: .: : . .: .:.:.:.. : :.:... :. CCDS38 KEIDDVYEKY-KKEDDLNQKKRLQQL--LQRALINSQELGDEKIQIVTQMLELVENRARQ 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 LD------ADLARFE-ADLKDKMEGSDFESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDT .. : :. : :. : ::..:. : :. : .. .... . : . ... CCDS38 MELHSQCFQDPAESERASDKAKMDSSQPERSSRRPRRQRTSESRDLCHMANGIEDCDDQP 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 PKKKKHKGGSEFTDT-ILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEW ::.:: :.... . . . .. ... .::::::::::.:::::::::::: .::::: CCDS38 PKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEW 180 190 200 210 220 230 220 230 240 pF1KB7 FHFACVDLTTKPKGKWFCPRCVQEKRKKK :::.::.:: ::::::.::.: ...: CCDS38 FHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR 240 250 260 270 280 >>CCDS44812.1 ING4 gene_id:51147|Hs108|chr12 (225 aa) initn: 889 init1: 513 opt: 567 Z-score: 531.7 bits: 105.7 E(32554): 2.7e-23 Smith-Waterman score: 992; 61.4% identity (80.7% similar) in 249 aa overlap (1-239:1-225) 10 20 30 40 50 60 pF1KB7 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ ::..::::::::.. ::::: ::.::.:....:: .. CCDS44 MAAGMYLEHYLDNL------------------------KAEIDKLATEYMSSARSLSSEE 10 20 30 70 80 90 100 110 pF1KB7 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD .. :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:.:: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB7 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPK--KKKHK---GGSEF---TDTILS ..::...: :::: ::::...:.:.. ..:.:..:: .:: : . :. . :. : CCDS44 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP ::::::::::::::::::::::::::::::::::::: ::::::::: :::::.:::::: CCDS44 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 160 170 180 190 200 210 240 pF1KB7 RCVQEKRKKK :: ::..:: CCDS44 RCSQERKKK 220 240 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:41:53 2016 done: Sat Nov 5 14:41:53 2016 Total Scan time: 1.800 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]