FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7945, 391 aa 1>>>pF1KB7945 391 - 391 aa - 391 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1236+/-0.000349; mu= 0.2625+/- 0.022 mean_var=226.2407+/-46.467, 0's: 0 Z-trim(120.7): 68 B-trim: 37 in 1/60 Lambda= 0.085269 statistics sampled from 36305 (36374) to 36305 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.426), width: 16 Scan time: 7.840 The best scores are: opt bits E(85289) NP_057953 (OMIM: 167414,615545) paired box protein ( 391) 2631 336.2 8.1e-92 XP_005251538 (OMIM: 167414,615545) PREDICTED: pair ( 390) 2527 323.4 5.7e-88 NP_001267477 (OMIM: 167414,615545) paired box prot ( 362) 2261 290.7 3.8e-78 NP_001267476 (OMIM: 167414,615545) paired box prot ( 357) 2027 261.9 1.7e-69 NP_001267481 (OMIM: 167414,615545) paired box prot ( 328) 2017 260.6 3.8e-69 NP_001267485 (OMIM: 167414,615545) paired box prot ( 283) 1899 246.1 8e-65 NP_000269 (OMIM: 120330,167409,191830,616002) pair ( 394) 1855 240.8 4.4e-63 NP_001291498 (OMIM: 120330,167409,191830,616002) p ( 425) 1855 240.8 4.7e-63 XP_016871777 (OMIM: 120330,167409,191830,616002) P ( 424) 1848 239.9 8.5e-63 XP_011516198 (OMIM: 167414,615545) PREDICTED: pair ( 410) 1752 228.1 3e-59 NP_001267478 (OMIM: 167414,615545) paired box prot ( 324) 1735 225.9 1.1e-58 NP_001267479 (OMIM: 167414,615545) paired box prot ( 295) 1728 225.0 1.8e-58 NP_003980 (OMIM: 120330,167409,191830,616002) pair ( 409) 1728 225.1 2.3e-58 XP_016871775 (OMIM: 120330,167409,191830,616002) P ( 440) 1728 225.2 2.4e-58 XP_011516199 (OMIM: 167414,615545) PREDICTED: pair ( 409) 1648 215.3 2.1e-55 NP_003979 (OMIM: 120330,167409,191830,616002) pair ( 396) 1546 202.7 1.2e-51 XP_016871776 (OMIM: 120330,167409,191830,616002) P ( 427) 1546 202.8 1.3e-51 XP_011510096 (OMIM: 167415,218700) PREDICTED: pair ( 387) 1536 201.5 2.8e-51 XP_011510095 (OMIM: 167415,218700) PREDICTED: pair ( 444) 1524 200.1 8.8e-51 NP_001267483 (OMIM: 167414,615545) paired box prot ( 348) 1310 173.7 6.1e-43 NP_001267480 (OMIM: 167414,615545) paired box prot ( 220) 1285 170.4 3.6e-42 NP_039246 (OMIM: 167415,218700) paired box protein ( 398) 1174 157.0 7.4e-38 XP_016860368 (OMIM: 167415,218700) PREDICTED: pair ( 402) 1169 156.4 1.1e-37 XP_011510094 (OMIM: 167415,218700) PREDICTED: pair ( 455) 1162 155.5 2.3e-37 XP_016860367 (OMIM: 167415,218700) PREDICTED: pair ( 459) 1157 154.9 3.5e-37 NP_003457 (OMIM: 167415,218700) paired box protein ( 450) 1138 152.6 1.7e-36 XP_011510093 (OMIM: 167415,218700) PREDICTED: pair ( 500) 1126 151.1 5.3e-36 XP_011510092 (OMIM: 167415,218700) PREDICTED: pair ( 507) 1126 151.2 5.3e-36 NP_001267484 (OMIM: 167414,615545) paired box prot ( 291) 1109 148.9 1.5e-35 NP_054698 (OMIM: 167415,218700) paired box protein ( 287) 1105 148.4 2.1e-35 NP_039247 (OMIM: 167415,218700) paired box protein ( 321) 1100 147.8 3.4e-35 NP_001267482 (OMIM: 167414,615545) paired box prot ( 319) 1069 144.0 4.8e-34 NP_003978 (OMIM: 120330,167409,191830,616002) pair ( 417) 1020 138.1 3.9e-32 XP_016871774 (OMIM: 120330,167409,191830,616002) P ( 448) 1020 138.1 4.1e-32 NP_003981 (OMIM: 120330,167409,191830,616002) pair ( 432) 1016 137.6 5.6e-32 XP_016871773 (OMIM: 120330,167409,191830,616002) P ( 463) 1016 137.6 5.9e-32 XP_016871778 (OMIM: 120330,167409,191830,616002) P ( 374) 820 113.4 9e-25 XP_016871772 (OMIM: 120330,167409,191830,616002) P ( 483) 820 113.5 1.1e-24 XP_016871771 (OMIM: 120330,167409,191830,616002) P ( 483) 820 113.5 1.1e-24 XP_016871770 (OMIM: 120330,167409,191830,616002) P ( 496) 820 113.5 1.1e-24 NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 755 105.4 2.4e-22 NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 755 105.5 2.5e-22 NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 755 105.5 2.5e-22 NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 755 105.5 2.5e-22 NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 755 105.5 2.5e-22 NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 694 98.0 5.1e-20 NP_006183 (OMIM: 167411,615560) paired box protein ( 534) 692 97.8 6.5e-20 NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 682 96.5 1.2e-19 NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 682 96.5 1.2e-19 NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 682 96.5 1.4e-19 >>NP_057953 (OMIM: 167414,615545) paired box protein Pax (391 aa) initn: 2631 init1: 2631 opt: 2631 Z-score: 1769.4 bits: 336.2 E(85289): 8.1e-92 Smith-Waterman score: 2631; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391) 10 20 30 40 50 60 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF 310 320 330 340 350 360 370 380 390 pF1KB7 PNPGLLGSPYYYSAAARGAAPPAAATAYDRH ::::::::::::::::::::::::::::::: NP_057 PNPGLLGSPYYYSAAARGAAPPAAATAYDRH 370 380 390 >>XP_005251538 (OMIM: 167414,615545) PREDICTED: paired b (390 aa) initn: 2522 init1: 2522 opt: 2527 Z-score: 1700.3 bits: 323.4 E(85289): 5.7e-88 Smith-Waterman score: 2527; 98.7% identity (99.0% similar) in 382 aa overlap (10-391:9-390) 10 20 30 40 50 60 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV : .: :::::::::::::::::::::::::::::::::::::::::::: XP_005 MEIHCKHDPFASMHRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF 300 310 320 330 340 350 370 380 390 pF1KB7 PNPGLLGSPYYYSAAARGAAPPAAATAYDRH ::::::::::::::::::::::::::::::: XP_005 PNPGLLGSPYYYSAAARGAAPPAAATAYDRH 360 370 380 390 >>NP_001267477 (OMIM: 167414,615545) paired box protein (362 aa) initn: 2290 init1: 2261 opt: 2261 Z-score: 1523.9 bits: 290.7 E(85289): 3.8e-78 Smith-Waterman score: 2347; 92.6% identity (92.6% similar) in 391 aa overlap (1-391:1-362) 10 20 30 40 50 60 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF ::::::::::::::::::::::::::::::::::::::: NP_001 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGS--------------------- 310 320 330 370 380 390 pF1KB7 PNPGLLGSPYYYSAAARGAAPPAAATAYDRH ::::::::::::::::::::::: NP_001 --------PYYYSAAARGAAPPAAATAYDRH 340 350 360 >>NP_001267476 (OMIM: 167414,615545) paired box protein (357 aa) initn: 2078 init1: 2018 opt: 2027 Z-score: 1368.4 bits: 261.9 E(85289): 1.7e-69 Smith-Waterman score: 2313; 91.3% identity (91.3% similar) in 391 aa overlap (1-391:1-357) 10 20 30 40 50 60 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF :::: :::::::::::::::::::::: NP_001 IVTG----------------------------------SEFSGSPYSHPQYSSYNDSWRF 310 320 370 380 390 pF1KB7 PNPGLLGSPYYYSAAARGAAPPAAATAYDRH ::::::::::::::::::::::::::::::: NP_001 PNPGLLGSPYYYSAAARGAAPPAAATAYDRH 330 340 350 >>NP_001267481 (OMIM: 167414,615545) paired box protein (328 aa) initn: 2042 init1: 2013 opt: 2017 Z-score: 1362.3 bits: 260.6 E(85289): 3.8e-69 Smith-Waterman score: 2039; 83.9% identity (83.9% similar) in 391 aa overlap (1-391:1-328) 10 20 30 40 50 60 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF :::: NP_001 IVTG-------------------------------------------------------- 370 380 390 pF1KB7 PNPGLLGSPYYYSAAARGAAPPAAATAYDRH :::::::::::::::::::::::: NP_001 -------SPYYYSAAARGAAPPAAATAYDRH 310 320 >>NP_001267485 (OMIM: 167414,615545) paired box protein (283 aa) initn: 1899 init1: 1899 opt: 1899 Z-score: 1284.8 bits: 246.1 E(85289): 8e-65 Smith-Waterman score: 1899; 100.0% identity (100.0% similar) in 283 aa overlap (109-391:1-283) 80 90 100 110 120 130 pF1KB7 KPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRI :::::::::::::::::::::::::::::: NP_001 MFAWEIRDRLLAERVCDNDTVPSVSSINRI 10 20 30 140 150 160 170 180 190 pF1KB7 IRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRK 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB7 RDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKP 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB7 EQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPH 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB7 VPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARG 220 230 240 250 260 270 380 390 pF1KB7 AAPPAAATAYDRH ::::::::::::: NP_001 AAPPAAATAYDRH 280 >>NP_000269 (OMIM: 120330,167409,191830,616002) paired b (394 aa) initn: 1563 init1: 883 opt: 1855 Z-score: 1253.5 bits: 240.8 E(85289): 4.4e-63 Smith-Waterman score: 1855; 70.7% identity (85.2% similar) in 399 aa overlap (1-391:1-394) 10 20 30 40 50 60 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV ::.. . . . ::::::::::::::::::::::::::::::::::::::::::::: NP_000 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_000 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVP--------ASSHSIVSTGSVTQVSSVST : .::::::::::::::::::::::: . :.: : .:.:: . . :::.:. NP_000 EGICDNDTVPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASN 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 DSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQ : .:: :::.::::: : .. .:::::: ..:. :::: : : : :::..:.: :::: NP_000 DPVGS-YSINGILGI--PRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQ 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 QLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSS :::.::::::: : :.: ..: :: :: .::: . .:. :::..:..:.. : ..::. NP_000 QLEALDRVFERPSYPDVFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSASTNPELGSN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 VPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYS : : :.::.:::::.::::::::::::::.::::: . ::.::::::::::.:::::::. NP_000 VSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYT 300 310 320 330 340 350 360 370 380 390 pF1KB7 SYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH .::..::: ::.::.:::::::: ::.:: :::.::::: NP_000 AYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH 360 370 380 390 >>NP_001291498 (OMIM: 120330,167409,191830,616002) paire (425 aa) initn: 1563 init1: 883 opt: 1855 Z-score: 1253.0 bits: 240.8 E(85289): 4.7e-63 Smith-Waterman score: 1855; 70.7% identity (85.2% similar) in 399 aa overlap (1-391:32-425) 10 20 30 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNG ::.. . . . ::::::::::::::: NP_001 EERAGPAVLKLSLRGDTAAAAALLPLLCLPMDMHCKADPFSAMHPGHGGVNQLGGVFVNG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQP ::::::.:::::::::::::::::::::::: .::::::::::::::::::::::: . : NP_001 ATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFH-P 130 140 150 160 170 180 160 170 180 190 200 pF1KB7 VP--------ASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEG .: : .:.:: . . :::.:.: .:: :::.::::: : .. .:::::: NP_001 TPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YSINGILGI--PRSNGEKRKRDED 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 IQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTT ..:. :::: : : : :::..:.: :::::::.::::::: : :.: ..: :: :: . NP_001 VSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGN 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB7 EYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPA ::: . .:. :::..:..:.. : ..::.: : :.::.:::::.::::::::::::::. NP_001 EYS-LPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPT 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB7 GQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPP ::::: . ::.::::::::::.:::::::..::..::: ::.::.:::::::: ::.:: NP_001 GQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPA 360 370 380 390 400 410 390 pF1KB7 AAATAYDRH :::.::::: NP_001 AAAAAYDRH 420 >>XP_016871777 (OMIM: 120330,167409,191830,616002) PREDI (424 aa) initn: 1552 init1: 872 opt: 1848 Z-score: 1248.4 bits: 239.9 E(85289): 8.5e-63 Smith-Waterman score: 1848; 70.7% identity (85.2% similar) in 399 aa overlap (1-391:32-424) 10 20 30 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNG ::.. . : .. :::::::::::::: XP_016 EERAGPAVLKLSLRGDTAAAAALLPLLCLPMDMHCK-ADPFSAMHRHGGVNQLGGVFVNG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQP ::::::.:::::::::::::::::::::::: .::::::::::::::::::::::: . : XP_016 ATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFH-P 130 140 150 160 170 160 170 180 190 200 pF1KB7 VP--------ASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEG .: : .:.:: . . :::.:.: .:: :::.::::: : .. .:::::: XP_016 TPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YSINGILGI--PRSNGEKRKRDED 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 IQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTT ..:. :::: : : : :::..:.: :::::::.::::::: : :.: ..: :: :: . XP_016 VSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGN 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB7 EYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPA ::: . .:. :::..:..:.. : ..::.: : :.::.:::::.::::::::::::::. XP_016 EYS-LPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPT 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB7 GQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPP ::::: . ::.::::::::::.:::::::..::..::: ::.::.:::::::: ::.:: XP_016 GQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPA 360 370 380 390 400 410 390 pF1KB7 AAATAYDRH :::.::::: XP_016 AAAAAYDRH 420 >>XP_011516198 (OMIM: 167414,615545) PREDICTED: paired b (410 aa) initn: 1794 init1: 1728 opt: 1752 Z-score: 1184.8 bits: 228.1 E(85289): 3e-59 Smith-Waterman score: 2583; 95.4% identity (95.4% similar) in 410 aa overlap (1-391:1-410) 10 20 30 40 50 60 pF1KB7 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV 190 200 210 220 230 240 250 260 270 280 pF1KB7 FERQHYSDIFTTTEPIKPEQ-------------------TTEYSAMASLAGGLDDMKANL :::::::::::::::::::: ::::::::::::::::::::: XP_011 FERQHYSDIFTTTEPIKPEQWCPVLMRQYLVQPQAVLFQTTEYSAMASLAGGLDDMKANL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 ASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEF 310 320 330 340 350 360 350 360 370 380 390 pF1KB7 SGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH 370 380 390 400 410 391 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:23:07 2016 done: Sat Nov 5 08:23:08 2016 Total Scan time: 7.840 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]