FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7947, 254 aa 1>>>pF1KB7947 254 - 254 aa - 254 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1351+/-0.000692; mu= 7.8930+/- 0.042 mean_var=148.3149+/-30.714, 0's: 0 Z-trim(115.2): 182 B-trim: 902 in 1/50 Lambda= 0.105313 statistics sampled from 15524 (15728) to 15524 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.483), width: 16 Scan time: 2.460 The best scores are: opt bits E(32554) CCDS11466.1 MEOX1 gene_id:4222|Hs108|chr17 ( 254) 1767 279.1 2e-75 CCDS11467.1 MEOX1 gene_id:4222|Hs108|chr17 ( 184) 1115 179.9 1e-45 CCDS42343.1 MEOX1 gene_id:4222|Hs108|chr17 ( 139) 919 150.1 7.7e-37 CCDS34605.1 MEOX2 gene_id:4223|Hs108|chr7 ( 304) 525 90.5 1.4e-18 >>CCDS11466.1 MEOX1 gene_id:4222|Hs108|chr17 (254 aa) initn: 1767 init1: 1767 opt: 1767 Z-score: 1467.7 bits: 279.1 E(32554): 2e-75 Smith-Waterman score: 1767; 100.0% identity (100.0% similar) in 254 aa overlap (1-254:1-254) 10 20 30 40 50 60 pF1KB7 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 EQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ 190 200 210 220 230 240 250 pF1KB7 DPEDGDSTASPSSE :::::::::::::: CCDS11 DPEDGDSTASPSSE 250 >>CCDS11467.1 MEOX1 gene_id:4222|Hs108|chr17 (184 aa) initn: 1107 init1: 1107 opt: 1115 Z-score: 934.2 bits: 179.9 E(32554): 1e-45 Smith-Waterman score: 1115; 91.0% identity (94.4% similar) in 177 aa overlap (1-177:1-176) 10 20 30 40 50 60 pF1KB7 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTK :::::::::::::::::::::::::::::::::::: .: .:. .: . :.: CCDS11 LGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESS-GQSVVPEPKDEVEACEGRSAHLP 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 EQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ CCDS11 QWAGP 180 >>CCDS42343.1 MEOX1 gene_id:4222|Hs108|chr17 (139 aa) initn: 919 init1: 919 opt: 919 Z-score: 774.9 bits: 150.1 E(32554): 7.7e-37 Smith-Waterman score: 919; 100.0% identity (100.0% similar) in 139 aa overlap (116-254:1-139) 90 100 110 120 130 140 pF1KB7 PAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTANETE :::::::::::::::::::::::::::::: CCDS42 MGTSSLGLVDTTGGPGDDYGVLGSTANETE 10 20 30 150 160 170 180 190 200 pF1KB7 KKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIA 40 50 60 70 80 90 210 220 230 240 250 pF1KB7 VNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGDSTASPSSE ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGDSTASPSSE 100 110 120 130 >>CCDS34605.1 MEOX2 gene_id:4223|Hs108|chr7 (304 aa) initn: 629 init1: 487 opt: 525 Z-score: 446.8 bits: 90.5 E(32554): 1.4e-18 Smith-Waterman score: 624; 47.5% identity (64.3% similar) in 255 aa overlap (17-233:4-249) 10 20 30 40 50 60 pF1KB7 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP :..::::.::. :.:: . . ...: . : .. :: CCDS34 MEHPLFGCLRSPHAT---AQGLHPFSQSSLALHGRSDHMS-----YP 10 20 30 70 80 90 pF1KB7 DFSASCLAATPHSLPQEEHIFTEQHPAFPQ-------------------SPNWHFPV--- ..:.: . . :.:: .:. :: . . :::.: CCDS34 ELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHHQQQQHQALQTNWHLPQMSS 40 50 60 70 80 90 100 110 120 130 140 pF1KB7 --SDARR----RPNSG--PAGGSKE----MGTSSLGLVDTTGG---PGDDYGVLGSTANE : ::. .:.:: : ::. ..:::: ::. ::: :: . . : CCDS34 PPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACAPGD-YGRQALSPAE 100 110 120 130 140 150 150 160 170 180 190 200 pF1KB7 TEKKSSRRRK-ESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRY .::.:. .:: .:::.::. : : .:: :::::::::::.::::::::::::::::::: CCDS34 AEKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRY 160 170 180 190 200 210 210 220 230 240 250 pF1KB7 EIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGDSTASPSSE ::::::::.:::::::::::::::::::::: CCDS34 EIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAA 220 230 240 250 260 270 CCDS34 TLQQTGDSIANEDSHDSDHSSEHAHL 280 290 300 254 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:43:09 2016 done: Sat Nov 5 14:43:09 2016 Total Scan time: 2.460 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]