FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7948, 375 aa 1>>>pF1KB7948 375 - 375 aa - 375 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0026+/-0.000939; mu= 11.3335+/- 0.057 mean_var=187.1416+/-39.646, 0's: 0 Z-trim(112.0): 163 B-trim: 0 in 0/52 Lambda= 0.093754 statistics sampled from 12623 (12815) to 12623 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.394), width: 16 Scan time: 2.890 The best scores are: opt bits E(32554) CCDS7613.1 TIAL1 gene_id:7073|Hs108|chr10 ( 375) 2624 367.1 1.5e-101 CCDS31295.1 TIAL1 gene_id:7073|Hs108|chr10 ( 392) 2341 328.8 5e-90 CCDS1900.1 TIA1 gene_id:7072|Hs108|chr2 ( 375) 2041 288.2 8e-78 CCDS1901.1 TIA1 gene_id:7072|Hs108|chr2 ( 386) 1516 217.2 1.9e-56 CCDS9311.1 PABPC3 gene_id:5042|Hs108|chr13 ( 631) 441 72.0 1.6e-12 >>CCDS7613.1 TIAL1 gene_id:7073|Hs108|chr10 (375 aa) initn: 2624 init1: 2624 opt: 2624 Z-score: 1936.8 bits: 367.1 E(32554): 1.5e-101 Smith-Waterman score: 2624; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375) 10 20 30 40 50 60 pF1KB7 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 GKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 KSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 KSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 GYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 GNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIP 310 320 330 340 350 360 370 pF1KB7 PPNQAGYGMASYQTQ ::::::::::::::: CCDS76 PPNQAGYGMASYQTQ 370 >>CCDS31295.1 TIAL1 gene_id:7073|Hs108|chr10 (392 aa) initn: 2341 init1: 2341 opt: 2341 Z-score: 1729.7 bits: 328.8 E(32554): 5e-90 Smith-Waterman score: 2580; 95.7% identity (95.7% similar) in 392 aa overlap (1-375:1-392) 10 20 30 40 pF1KB7 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITE----------------- ::::::::::::::::::::::::::::::::::::::::::: CCDS31 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGD 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 LSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWL 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 GGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQ 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 TFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTK 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 NFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 NFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG 310 320 330 340 350 360 350 360 370 pF1KB7 GFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ :::::::::::::::::::::::::::::::: CCDS31 GFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ 370 380 390 >>CCDS1900.1 TIA1 gene_id:7072|Hs108|chr2 (375 aa) initn: 1977 init1: 1690 opt: 2041 Z-score: 1510.6 bits: 288.2 E(32554): 8e-78 Smith-Waterman score: 2041; 79.5% identity (90.0% similar) in 380 aa overlap (2-375:1-375) 10 20 30 40 50 60 pF1KB7 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD :::. .:.:::::::::::::.:::::::::::::.:::: . ..:::::::::.::: CCDS19 MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRH 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPF :::::::::::::.::::::::::::::::::::::::::::::::::::::::.::::: CCDS19 AAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 GKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAP :.:::::::::::::::::::::::.:: :::::: .::::::::::::::::::::::: CCDS19 GRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 KSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK ::: :.::::: ...:::::::.::::::::..::::.::::::::::::::::::::.: CCDS19 KSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK 180 190 200 210 220 230 250 260 270 280 290 pF1KB7 GYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQ---VDYSQ-WGQW :::::::..::::::::::::::::::::::::::::. :: . :: . : : .::: CCDS19 GYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQW 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 SQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG-GFGAQPPQGQAP .: ::: :: :::: :::::: ::.::: ::::::. :: :: ::: ..:.:::::: CCDS19 GQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWMGPNYGVQPPQGQNG 300 310 320 330 340 350 360 370 pF1KB7 PPVIPPPNQ-AGYGMASYQTQ . ::: .:: .:.:.:: CCDS19 SML---PNQPSGYRVAGYETQ 360 370 >>CCDS1901.1 TIA1 gene_id:7072|Hs108|chr2 (386 aa) initn: 1450 init1: 1163 opt: 1516 Z-score: 1126.7 bits: 217.2 E(32554): 1.9e-56 Smith-Waterman score: 2004; 77.0% identity (87.5% similar) in 391 aa overlap (2-375:1-386) 10 20 30 40 50 60 pF1KB7 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD :::. .:.:::::::::::::.:::::::::::::.:::: . ..:::::::::.::: CCDS19 MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRH 10 20 30 40 50 70 80 90 100 pF1KB7 AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTS-----------NHFHVFVGDLSPEIT :::::::::::::.:::::::::::::::::::: .:::::::::::::: CCDS19 AAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEIT 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 TEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR :::::.::::::.:::::::::::::::::::::::.:: :::::: .:::::::::::: CCDS19 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 TNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFG :::::::::::::: :.::::: ...:::::::.::::::::..::::.::::::::::: CCDS19 TNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 QIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQ-- :::::::::.::::::::..::::::::::::::::::::::::::::. :: . :: CCDS19 QIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQN 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 -VDYSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG-G . : : .:::.: ::: :: :::: :::::: ::.::: ::::::. :: :: ::: . CCDS19 QIGYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWMGPN 300 310 320 330 340 350 350 360 370 pF1KB7 FGAQPPQGQAPPPVIPPPNQ-AGYGMASYQTQ .:.:::::: . ::: .:: .:.:.:: CCDS19 YGVQPPQGQNGSML---PNQPSGYRVAGYETQ 360 370 380 >>CCDS9311.1 PABPC3 gene_id:5042|Hs108|chr13 (631 aa) initn: 357 init1: 148 opt: 441 Z-score: 338.4 bits: 72.0 E(32554): 1.6e-12 Smith-Waterman score: 441; 27.0% identity (60.1% similar) in 363 aa overlap (11-361:101-450) 10 20 30 40 pF1KB7 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKM ..: ::...... . . : .: ::.. CCDS93 TMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNV 80 90 100 110 120 130 50 60 70 80 90 pF1KB7 ITEHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDT---SNHF . ..... : ::.: :. : :. ::: . :..: :. . . .. . ...: CCDS93 VCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEF 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB7 -HVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIV .:.. ... .. : .:. :. :: ...:. : .:::::.::::: . ::..:. CCDS93 PNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVD 200 210 220 230 240 160 170 180 190 200 210 pF1KB7 HMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGL .:.:. :.:.:: .. : .: . ..:. . : . .: ... . : .: .. .:. CCDS93 EMNGKELNGKQIYVGRAQKK--VERQTELKRTFEQMKQDRITRYQVVN--LYVKNLDDGI 250 260 270 280 290 300 220 230 240 250 260 270 pF1KB7 TDQLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKC :. .:..::::: : .:. : ::..:: ::. : :..:.. .:: . . . CCDS93 DDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYV 310 320 330 340 350 360 280 290 300 310 320 pF1KB7 YWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQY----GQYMANGWQVPPYGVYGQPWNQ .... . . . .: : . ..: . :.: : .:. :. ...: : .: CCDS93 ALAQRKEE-RQAYLTNEYMQ--RMASVRAVPNQRAPPSGYFMTAVPQTQNHAAYYPP-SQ 370 380 390 400 410 420 330 340 350 360 370 pF1KB7 QGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ . :: : . ::.: : : .: : CCDS93 IA---RLRPSPRWTAQ-GARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQRVA 430 440 450 460 470 CCDS93 NTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQGQ 480 490 500 510 520 530 375 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:14:35 2016 done: Sat Nov 5 10:14:35 2016 Total Scan time: 2.890 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]