FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7950, 394 aa 1>>>pF1KB7950 394 - 394 aa - 394 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6705+/-0.000776; mu= 10.0753+/- 0.047 mean_var=207.0744+/-41.432, 0's: 0 Z-trim(117.0): 21 B-trim: 174 in 1/52 Lambda= 0.089127 statistics sampled from 17720 (17740) to 17720 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.836), E-opt: 0.2 (0.545), width: 16 Scan time: 3.640 The best scores are: opt bits E(32554) CCDS53300.1 MYCL gene_id:4610|Hs108|chr1 ( 394) 2775 368.6 5.6e-102 CCDS30682.1 MYCL gene_id:4610|Hs108|chr1 ( 364) 2549 339.5 3e-93 CCDS44117.2 MYCL gene_id:4610|Hs108|chr1 ( 236) 1460 199.3 3.1e-51 CCDS1687.1 MYCN gene_id:4613|Hs108|chr2 ( 464) 465 71.6 1.6e-12 >>CCDS53300.1 MYCL gene_id:4610|Hs108|chr1 (394 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1944.3 bits: 368.6 E(32554): 5.6e-102 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394) 10 20 30 40 50 60 pF1KB7 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRSTAPSEDIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRSTAPSEDIW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KKFELVPSPPTSPPWGLGPGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYASII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KKFELVPSPPTSPPWGLGPGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYASII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RRDCMWSGFSARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 RRDCMWSGFSARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 QHNYAARFPPESCSQEEASERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSCHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QHNYAARFPPESCSQEEASERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSCHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 KPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYL 310 320 330 340 350 360 370 380 390 pF1KB7 QALVGAEKRMATEKRQLRCRQQQLQKRIAYLTGY :::::::::::::::::::::::::::::::::: CCDS53 QALVGAEKRMATEKRQLRCRQQQLQKRIAYLTGY 370 380 390 >>CCDS30682.1 MYCL gene_id:4610|Hs108|chr1 (364 aa) initn: 2549 init1: 2549 opt: 2549 Z-score: 1787.7 bits: 339.5 E(32554): 3e-93 Smith-Waterman score: 2549; 100.0% identity (100.0% similar) in 364 aa overlap (31-394:1-364) 10 20 30 40 50 60 pF1KB7 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRSTAPSEDIW :::::::::::::::::::::::::::::: CCDS30 MDYDSYQHYFYDYDCGEDFYRSTAPSEDIW 10 20 30 70 80 90 100 110 120 pF1KB7 KKFELVPSPPTSPPWGLGPGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYASII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 KKFELVPSPPTSPPWGLGPGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYASII 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 RRDCMWSGFSARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 RRDCMWSGFSARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 PKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 PKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQ 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 QHNYAARFPPESCSQEEASERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSCHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 QHNYAARFPPESCSQEEASERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSCHP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB7 KPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 KPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYL 280 290 300 310 320 330 370 380 390 pF1KB7 QALVGAEKRMATEKRQLRCRQQQLQKRIAYLTGY :::::::::::::::::::::::::::::::::: CCDS30 QALVGAEKRMATEKRQLRCRQQQLQKRIAYLTGY 340 350 360 >>CCDS44117.2 MYCL gene_id:4610|Hs108|chr1 (236 aa) initn: 1482 init1: 1460 opt: 1460 Z-score: 1033.2 bits: 199.3 E(32554): 3.1e-51 Smith-Waterman score: 1460; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195) 10 20 30 40 50 60 pF1KB7 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRSTAPSEDIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRSTAPSEDIW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KKFELVPSPPTSPPWGLGPGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYASII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KKFELVPSPPTSPPWGLGPGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYASII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RRDCMWSGFSARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RRDCMWSGFSARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQ ::::::::::::::: CCDS44 PKTQACSGSESPSDSGKDLPEPSKRGPPHGWPKLCPCLRSGIGSSQALGPSPPLFG 190 200 210 220 230 >>CCDS1687.1 MYCN gene_id:4613|Hs108|chr2 (464 aa) initn: 695 init1: 314 opt: 465 Z-score: 338.1 bits: 71.6 E(32554): 1.6e-12 Smith-Waterman score: 595; 36.7% identity (53.1% similar) in 441 aa overlap (52-390:42-460) 30 40 50 60 70 80 pF1KB7 AGGWSEGADMDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGA :: :.:::::::::.:.:: :: :.. . CCDS16 MICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHS 20 30 40 50 60 70 90 100 110 120 130 pF1KB7 GDPAPGIGP----PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLER ..: . : : :. . ..: . : : : .: .:::::::::::.::: CCDS16 SEPPSWVTEMLLENELW-GSPAEEDAFGLGGLGGLTPN--PVILQDCMWSGFSAREKLER 80 90 100 110 120 140 150 160 pF1KB7 AVSDRL--------------APGA----P--RGNPPKASA--------------APDCT- :::..: .::: : ::. :.: : .:. CCDS16 AVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVD 130 140 150 160 170 180 170 180 pF1KB7 PSL--------EAGNPAPAAPC-----------------PLGEP---------------- :.. . :.:::: : : : CCDS16 PAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGD 190 200 210 220 230 240 190 200 210 220 pF1KB7 -KTQACSGSESPSDS---------ENEEIDVVTVEKRQSLGIRKPVT---ITVRAD--PL :. . :: .. ::: :.:::::::::::.: . : :: :::: : CCDS16 HKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAAL 250 260 270 280 290 300 230 240 250 260 270 pF1KB7 DPCMKHFH-------ISIHQQQHNYAARFPPESCSQEEASERGPQEEVLERDAAGEKEDE : . . :::: ::::: : .:.: ::... .. :. . . CCDS16 GPGRAQSSELILKRCLPIHQQ-HNYAA--PSPYVESEDAP---PQKKI--KSEASPRPLK 310 320 330 340 350 360 280 290 300 310 320 330 pF1KB7 EDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVP : :: :.: :. .::.:: .:.:::.:::.::::::: ::.:::.:: CCDS16 S----VIPPK-----AKSLSPR--NSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVP 370 380 390 400 340 350 360 370 380 390 pF1KB7 TLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAYLTGY :.. :: :::::.:: ::...: . :... ::..:. ::::: :.: . CCDS16 ELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC 410 420 430 440 450 460 394 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:43:46 2016 done: Sat Nov 5 14:43:46 2016 Total Scan time: 3.640 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]