FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7951, 255 aa 1>>>pF1KB7951 255 - 255 aa - 255 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3666+/-0.000282; mu= 6.7272+/- 0.018 mean_var=150.1393+/-30.868, 0's: 0 Z-trim(122.4): 274 B-trim: 36 in 1/56 Lambda= 0.104671 statistics sampled from 40072 (40410) to 40072 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.474), width: 16 Scan time: 8.160 The best scores are: opt bits E(85289) NP_835221 (OMIM: 600029) homeobox protein DLX-1 is ( 255) 1712 269.2 4.9e-72 NP_005213 (OMIM: 600030) homeobox protein DLX-6 [H ( 293) 769 126.9 4e-29 NP_001033582 (OMIM: 600029) homeobox protein DLX-1 ( 129) 733 121.2 9.3e-28 NP_612138 (OMIM: 601911,616788) homeobox protein D ( 240) 534 91.3 1.7e-18 NP_001925 (OMIM: 601911,616788) homeobox protein D ( 168) 481 83.2 3.3e-16 XP_016879780 (OMIM: 601911,616788) PREDICTED: home ( 168) 481 83.2 3.3e-16 NP_005212 (OMIM: 220600,600028) homeobox protein D ( 289) 476 82.6 8.3e-16 NP_004396 (OMIM: 126255) homeobox protein DLX-2 [H ( 328) 471 81.9 1.6e-15 NP_005211 (OMIM: 104510,190320,600525) homeobox pr ( 287) 466 81.1 2.4e-15 XP_005250242 (OMIM: 220600,600028) PREDICTED: home ( 161) 430 75.5 6.6e-14 XP_016867292 (OMIM: 220600,600028) PREDICTED: home ( 161) 430 75.5 6.6e-14 NP_067545 (OMIM: 603260) homeobox protein BarH-lik ( 254) 281 53.2 5.5e-07 NP_064447 (OMIM: 605212) barH-like 2 homeobox prot ( 387) 283 53.6 6.2e-07 NP_002440 (OMIM: 123101,168500,168550,604757) home ( 267) 276 52.4 9.7e-07 NP_003649 (OMIM: 604823) homeobox protein BarH-lik ( 279) 274 52.1 1.2e-06 NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 273 52.0 1.5e-06 XP_011541345 (OMIM: 604823) PREDICTED: homeobox pr ( 233) 270 51.5 1.6e-06 NP_001129743 (OMIM: 217095,611770) homeobox protei ( 301) 270 51.5 2e-06 NP_064448 (OMIM: 605211) barH-like 1 homeobox prot ( 327) 255 49.3 1e-05 NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 ( 367) 251 48.7 1.7e-05 XP_016868632 (OMIM: 610772) PREDICTED: homeobox pr ( 265) 247 48.0 2e-05 NP_001091639 (OMIM: 611074) brain-specific homeobo ( 233) 245 47.7 2.2e-05 NP_005184 (OMIM: 300025) homeobox protein CDX-4 [H ( 284) 246 47.9 2.3e-05 NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 ( 354) 247 48.1 2.5e-05 NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 245 47.8 2.8e-05 NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 245 47.8 2.9e-05 NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 245 47.8 3.1e-05 NP_001182446 (OMIM: 186770) T-cell leukemia homeob ( 257) 242 47.3 3.3e-05 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 245 47.9 3.4e-05 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 244 47.7 4.1e-05 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 244 47.7 4.1e-05 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 244 47.7 4.1e-05 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 244 47.7 4.1e-05 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 244 47.7 4.1e-05 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 244 47.7 4.1e-05 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 244 47.7 4.1e-05 NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 ( 273) 240 47.0 4.3e-05 NP_001158727 (OMIM: 142994,176450) motor neuron an ( 189) 237 46.4 4.4e-05 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 240 47.0 4.7e-05 NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 ( 239) 238 46.6 4.7e-05 NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 ( 364) 240 47.1 5.3e-05 NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 239 47.0 6.5e-05 NP_004378 (OMIM: 108900,187500,217095,225250,60058 ( 324) 237 46.6 6.7e-05 NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 235 46.2 7.2e-05 XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 235 46.2 7.2e-05 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 234 46.1 8.6e-05 NP_796374 (OMIM: 605955) homeobox protein Nkx-6.2 ( 277) 233 45.9 9e-05 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 234 46.2 9.9e-05 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 234 46.2 9.9e-05 NP_001092304 (OMIM: 603354) homeobox protein GBX-1 ( 363) 234 46.2 0.0001 >>NP_835221 (OMIM: 600029) homeobox protein DLX-1 isofor (255 aa) initn: 1712 init1: 1712 opt: 1712 Z-score: 1414.2 bits: 269.2 E(85289): 4.9e-72 Smith-Waterman score: 1712; 100.0% identity (100.0% similar) in 255 aa overlap (1-255:1-255) 10 20 30 40 50 60 pF1KB7 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_835 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_835 SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_835 FNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGSYIPSYTSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_835 SKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGSYIPSYTSW 190 200 210 220 230 240 250 pF1KB7 YPSAHQEAMQQPQLM ::::::::::::::: NP_835 YPSAHQEAMQQPQLM 250 >>NP_005213 (OMIM: 600030) homeobox protein DLX-6 [Homo (293 aa) initn: 816 init1: 550 opt: 769 Z-score: 643.8 bits: 126.9 E(85289): 4e-29 Smith-Waterman score: 824; 56.4% identity (75.7% similar) in 243 aa overlap (25-255:55-293) 10 20 30 40 50 pF1KB7 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPD : .:: ::. :. .:: .::::::. . NP_005 GQQQQQQQQQQQQQQQQQQQPPPPPPPPPQPHSQQSSPA-MAGAHYPLHCLHSAAAAAAA 30 40 50 60 70 80 60 70 80 90 100 pF1KB7 GAYSSASSFSRPLGYPYV----NSVS--SHASSPYISS------VQSYPGSASLAQSRLE :.. . : ::. :: . : :. ::.: .::: .:.. ::.: . NP_005 GSHHHHHHQHHHHGSPYASGGGNSYNHRSLAAYPYMSHSQHSPYLQSYHNSSAAAQTRGD 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB7 DPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELA : .:..:.::.:.::.:::::::::::::::::::::::::.::::::::::::::::: NP_005 D--TDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELA 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB7 ASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSS ::::::::::::::::::::::::.:::. :.. : .. ::: :: .:: :. :.: NP_005 ASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRSPALPPVWDV-SAS 210 220 230 240 250 260 230 240 250 pF1KB7 GKGSGGNAGSYIPSYTSWYPSAHQEAMQQPQLM .:: . .::.:.:. :: : ::..::.::.: NP_005 AKGVSMPPNSYMPGYSHWYSSPHQDTMQRPQMM 270 280 290 >>NP_001033582 (OMIM: 600029) homeobox protein DLX-1 iso (129 aa) initn: 770 init1: 725 opt: 733 Z-score: 619.3 bits: 121.2 E(85289): 9.3e-28 Smith-Waterman score: 733; 86.7% identity (92.2% similar) in 128 aa overlap (1-125:1-128) 10 20 30 40 50 60 pF1KB7 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGAD---SEKSTVVEGG ::::::::::::::::::::::::::::::::::::::::::::: : .. : :. NP_001 SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGQDLVPKQAIQVQEAD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 EVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQ :. ..:.: NP_001 EAGWGGSGG >>NP_612138 (OMIM: 601911,616788) homeobox protein DLX-4 (240 aa) initn: 479 init1: 404 opt: 534 Z-score: 453.2 bits: 91.3 E(85289): 1.7e-18 Smith-Waterman score: 547; 43.9% identity (63.0% similar) in 262 aa overlap (3-255:1-240) 10 20 30 40 50 60 pF1KB7 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA ::..: : . ..:::: :. ..: : . : . : : : : : NP_612 MTSLPCPLPGRDASKAVF-----PD--LAPVPSVAAAYPL------GLS-PTTAASPN 10 20 30 40 70 80 90 100 110 pF1KB7 SSFSRPLG----YPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPG---ADSEKSTV :.::: : :::.. .. : :.: : : : : : ::::: . NP_612 LSYSRPYGHLLSYPYTEPANPGDS--YLSCQQPAALSQPLCGPA-EHPQELEADSEKPRL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 V-EGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQV : .: : .. .::.::::::::::::: ::.:::.::::::::::.:::.:::::::: NP_612 SPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQV 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 KIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWN-PNSSSGKGSGGNAG ::::::::::.:::.::.... ::. . ..: :::.: :. :.... :: NP_612 KIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSG---- 170 180 190 200 210 240 250 pF1KB7 SYIPSYTSWYPSAHQEAMQQPQLM : :. .:: .... .::.: NP_612 -YGNSFGAWYQHHSSDVLASPQMM 220 230 240 >>NP_001925 (OMIM: 601911,616788) homeobox protein DLX-4 (168 aa) initn: 454 init1: 404 opt: 481 Z-score: 412.1 bits: 83.2 E(85289): 3.3e-16 Smith-Waterman score: 481; 53.6% identity (76.2% similar) in 151 aa overlap (107-255:23-168) 80 90 100 110 120 130 pF1KB7 SHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVV-EGGEVRFNGKGKKIRKPRTIY :::: . : .: : .. .::.::::::: NP_001 MKLSVLPPRSLLAPYTVLCCPPDSEKPRLSPEPSERRPQAPAKKLRKPRTIY 10 20 30 40 50 140 150 160 170 180 190 pF1KB7 SSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALE :::::: ::.:::.::::::::::.:::.::::::::::::::::::.:::.::.... : NP_001 SSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQE 60 70 80 90 100 110 200 210 220 230 240 250 pF1KB7 GSALANGRALSAGSPPVPPGWN-PNSSSGKGSGGNAGSYIPSYTSWYPSAHQEAMQQPQL :. . ..: :::.: :. :.... :: : :. .:: .... .::. NP_001 GDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSG-----YGNSFGAWYQHHSSDVLASPQM 120 130 140 150 160 pF1KB7 M : NP_001 M >>XP_016879780 (OMIM: 601911,616788) PREDICTED: homeobox (168 aa) initn: 454 init1: 404 opt: 481 Z-score: 412.1 bits: 83.2 E(85289): 3.3e-16 Smith-Waterman score: 481; 53.6% identity (76.2% similar) in 151 aa overlap (107-255:23-168) 80 90 100 110 120 130 pF1KB7 SHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVV-EGGEVRFNGKGKKIRKPRTIY :::: . : .: : .. .::.::::::: XP_016 MKLSVLPPRSLLAPYTVLCCPPDSEKPRLSPEPSERRPQAPAKKLRKPRTIY 10 20 30 40 50 140 150 160 170 180 190 pF1KB7 SSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALE :::::: ::.:::.::::::::::.:::.::::::::::::::::::.:::.::.... : XP_016 SSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQE 60 70 80 90 100 110 200 210 220 230 240 250 pF1KB7 GSALANGRALSAGSPPVPPGWN-PNSSSGKGSGGNAGSYIPSYTSWYPSAHQEAMQQPQL :. . ..: :::.: :. :.... :: : :. .:: .... .::. XP_016 GDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSG-----YGNSFGAWYQHHSSDVLASPQM 120 130 140 150 160 pF1KB7 M : XP_016 M >>NP_005212 (OMIM: 220600,600028) homeobox protein DLX-5 (289 aa) initn: 430 init1: 389 opt: 476 Z-score: 404.7 bits: 82.6 E(85289): 8.3e-16 Smith-Waterman score: 501; 44.0% identity (63.1% similar) in 252 aa overlap (5-244:36-263) 10 20 30 pF1KB7 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSP :.::: : ... : :. ::. NP_005 DRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPES--SATDSDYYSPTGGAPHGYCSPTS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 MSHGHYSMHCLHSAGHSQPDGAYSSASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSA :.:. :. . : :. .::.: :: ....:. : :: ..: : NP_005 ASYGK----ALNPYQY-QYHGVNGSAGS------YP----AKAYADYSYASSYHQYGG-- 70 80 90 100 100 110 120 130 140 150 pF1KB7 SLAQSRLEDPGADSEKSTVVEGGEVRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYL : .:. :.: .. : :::. ::: ::.:::::::::.:: ::.::::.:::: NP_005 --AYNRV--PSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYL 110 120 130 140 150 160 160 170 180 190 200 210 pF1KB7 ALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVP :::::::::::::::::::::::::::::.::.::.: : : ... .. .:: : NP_005 ALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSP-SSSDPMACNSPQSP 170 180 190 200 210 220 220 230 240 250 pF1KB7 PGWNPNSSSGKGSG-----------GNAGSYIPSYTSWYPSAHQEAMQQPQLM :.:..:: . : . :.::. . .::: :: NP_005 AVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPL 230 240 250 260 270 280 NP_005 ALASGTLY >>NP_004396 (OMIM: 126255) homeobox protein DLX-2 [Homo (328 aa) initn: 426 init1: 394 opt: 471 Z-score: 399.9 bits: 81.9 E(85289): 1.6e-15 Smith-Waterman score: 471; 44.4% identity (63.8% similar) in 232 aa overlap (29-248:51-275) 10 20 30 40 50 pF1KB7 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPS-PMS---HGHYSMHCLHSAGHSQPD : ::. :.: . : . : :: . NP_004 STYHQHQQPPSGGGAGPGGNSSSSSSLHKPQESPTLPVSTATDSSYYTNQQHPAGGGGGG 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB7 GA-YSSASSFSRPLGYPYVNSVSSHASSPY-ISSVQSYPGSASLAQSRLEDPGADSEKST :. :. .:.. . .:.: :.: : .. . .: . : . : .:. . .. NP_004 GSPYAHMGSYQYQASG--LNNVPYSAKSSYDLGYTAAYTSYAPYGTS--SSPANNEPEKE 90 100 110 120 130 120 130 140 150 160 170 pF1KB7 VVEGGEVRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQ .: :.:. ::: ::.:::::::::.:: ::.::::.:::::::::::::::::::::: NP_004 DLEP-EIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQ 140 150 160 170 180 190 180 190 200 210 220 pF1KB7 VKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPV--PPGWN---PNSSSGKGS :::::::.::::::. :.: : :.. : :::: : .:. :. .: :. NP_004 VKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPPCA-SPPVSAPASWDFGVPQRMAGGGG 200 210 220 230 240 250 230 240 250 pF1KB7 GGNAGSYIPSYTSWYPSAHQEAMQQPQLM :..:: : : ::. : NP_004 PGSGGSGAGSSGS-SPSSAASAFLGNYPWYHQTSGSASHLQATAPLLHPTQTPQPHHHHH 260 270 280 290 300 310 >>NP_005211 (OMIM: 104510,190320,600525) homeobox protei (287 aa) initn: 457 init1: 388 opt: 466 Z-score: 396.6 bits: 81.1 E(85289): 2.4e-15 Smith-Waterman score: 477; 41.0% identity (60.5% similar) in 266 aa overlap (24-254:3-262) 10 20 30 40 50 pF1KB7 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQP------- : ....: : .. :. : :......: NP_005 MSGSFDRKLS-SILTDISSSLSC-HAGSKDSPTLPESSV 10 20 30 60 70 80 90 pF1KB7 -DGAYSSASSFSRPLGYPY---VNSVSSH--------ASSPYISSVQSYPGSASLAQ--S : .: :: . . : :: :: . : :.. : . : .:: : . NP_005 TDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGA 40 50 60 70 80 90 100 110 120 130 140 150 pF1KB7 RLEDPGADSEKSTVVEG--GEVRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALP :.: .. .: : .:::. ::: ::.::::::::: :: ::.::::..:::::: NP_005 YREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALP 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB7 ERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGW :::::::.::::::::::::::.:::::::.:.: . :: : :. ... .::: : : NP_005 ERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSP-NNSDSMACNSPPSPALW 160 170 180 190 200 210 220 230 240 250 pF1KB7 NPNSSSGKGSGGNA------GSYIPSY-----TSWYPSAHQEAMQQPQLM . .: : . . . : ::: .::: : . .. :.: NP_005 DTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWY---HAQNLSGPHLQQQPPQPATLH 220 230 240 250 260 270 NP_005 HASPGPPPNPGAVY 280 >>XP_005250242 (OMIM: 220600,600028) PREDICTED: homeobox (161 aa) initn: 453 init1: 389 opt: 430 Z-score: 370.7 bits: 75.5 E(85289): 6.6e-14 Smith-Waterman score: 447; 58.2% identity (74.6% similar) in 134 aa overlap (122-244:3-135) 100 110 120 130 140 150 pF1KB7 GSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQ ::: ::.:::::::::.:: ::.::::.:: XP_005 MVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQ 10 20 30 160 170 180 190 200 210 pF1KB7 YLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPP :::::::::::::::::::::::::::::::.::.::.: : : ... .. .:: XP_005 YLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSP-SSSDPMACNSPQ 40 50 60 70 80 90 220 230 240 250 pF1KB7 VPPGWNPNSSSGKGSG-----------GNAGSYIPSYTSWYPSAHQEAMQQPQLM : :.:..:: . : . :.::. . .::: :: XP_005 SPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQH 100 110 120 130 140 150 XP_005 PLALASGTLY 160 255 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:15:13 2016 done: Sat Nov 5 10:15:15 2016 Total Scan time: 8.160 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]