FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7953, 256 aa 1>>>pF1KB7953 256 - 256 aa - 256 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4778+/-0.000383; mu= 14.4095+/- 0.024 mean_var=98.5847+/-19.564, 0's: 0 Z-trim(114.1): 182 B-trim: 0 in 0/54 Lambda= 0.129172 statistics sampled from 23497 (23742) to 23497 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.278), width: 16 Scan time: 6.610 The best scores are: opt bits E(85289) NP_038462 (OMIM: 604662) calsenilin isoform 1 [Hom ( 256) 1713 329.6 3.5e-90 NP_001030086 (OMIM: 604662) calsenilin isoform 2 p ( 230) 1303 253.1 3.2e-67 NP_079497 (OMIM: 608182) Kv channel-interacting pr ( 250) 1074 210.5 2.4e-54 NP_001030175 (OMIM: 608182) Kv channel-interacting ( 225) 1070 209.7 3.7e-54 NP_671710 (OMIM: 608182) Kv channel-interacting pr ( 216) 1068 209.3 4.7e-54 NP_671712 (OMIM: 608182) Kv channel-interacting pr ( 229) 1066 208.9 6.3e-54 XP_005248247 (OMIM: 608182) PREDICTED: Kv channel- ( 233) 1066 208.9 6.4e-54 NP_775286 (OMIM: 604661) Kv channel-interacting pr ( 225) 1046 205.2 8.3e-53 NP_775287 (OMIM: 604661) Kv channel-interacting pr ( 220) 1043 204.6 1.2e-52 NP_001030176 (OMIM: 608182) Kv channel-interacting ( 188) 1036 203.3 2.7e-52 NP_671711 (OMIM: 608182) Kv channel-interacting pr ( 188) 1036 203.3 2.7e-52 XP_016864142 (OMIM: 608182) PREDICTED: Kv channel- ( 188) 1036 203.3 2.7e-52 NP_775284 (OMIM: 604661) Kv channel-interacting pr ( 252) 1035 203.2 3.7e-52 XP_016871650 (OMIM: 604661) PREDICTED: Kv channel- ( 230) 1034 203.0 4e-52 NP_775283 (OMIM: 604661) Kv channel-interacting pr ( 270) 1034 203.0 4.4e-52 NP_055406 (OMIM: 604661) Kv channel-interacting pr ( 285) 1034 203.1 4.6e-52 NP_775285 (OMIM: 604661) Kv channel-interacting pr ( 227) 1019 200.2 2.7e-51 XP_016864896 (OMIM: 604660) PREDICTED: Kv channel- ( 225) 1004 197.4 1.9e-50 NP_001030010 (OMIM: 604660) Kv channel-interacting ( 225) 1004 197.4 1.9e-50 NP_055407 (OMIM: 604660) Kv channel-interacting pr ( 216) 1002 197.0 2.4e-50 NP_001030009 (OMIM: 604660) Kv channel-interacting ( 227) 1002 197.0 2.5e-50 XP_011512184 (OMIM: 608182) PREDICTED: Kv channel- ( 257) 990 194.8 1.3e-49 XP_011512187 (OMIM: 608182) PREDICTED: Kv channel- ( 232) 986 194.0 2e-49 XP_011512188 (OMIM: 608182) PREDICTED: Kv channel- ( 223) 984 193.6 2.5e-49 XP_011512186 (OMIM: 608182) PREDICTED: Kv channel- ( 236) 982 193.3 3.3e-49 XP_011512185 (OMIM: 608182) PREDICTED: Kv channel- ( 240) 982 193.3 3.4e-49 NP_001265269 (OMIM: 604660) Kv channel-interacting ( 188) 978 192.5 4.8e-49 XP_011538033 (OMIM: 604661) PREDICTED: Kv channel- ( 230) 963 189.7 3.8e-48 XP_005269787 (OMIM: 604661) PREDICTED: Kv channel- ( 225) 960 189.2 5.5e-48 XP_011512191 (OMIM: 608182) PREDICTED: Kv channel- ( 195) 952 187.6 1.4e-47 XP_011512189 (OMIM: 608182) PREDICTED: Kv channel- ( 195) 952 187.6 1.4e-47 XP_005269786 (OMIM: 604661) PREDICTED: Kv channel- ( 257) 952 187.7 1.7e-47 XP_006717875 (OMIM: 604661) PREDICTED: Kv channel- ( 275) 951 187.6 2e-47 NP_001265268 (OMIM: 604660) Kv channel-interacting ( 241) 677 136.5 4.4e-32 NP_055101 (OMIM: 603315) neuronal calcium sensor 1 ( 190) 578 117.9 1.3e-26 NP_001122298 (OMIM: 603315) neuronal calcium senso ( 172) 541 111.0 1.5e-24 XP_005246218 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 538 110.5 2.3e-24 XP_005246219 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 538 110.5 2.3e-24 XP_016859441 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 538 110.5 2.3e-24 XP_016859440 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 538 110.5 2.3e-24 XP_016859442 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 538 110.5 2.3e-24 NP_002134 (OMIM: 142622,224500) neuron-specific ca ( 193) 538 110.5 2.3e-24 NP_001245287 (OMIM: 600207) hippocalcin-like prote ( 193) 538 110.5 2.3e-24 XP_005246220 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 538 110.5 2.3e-24 XP_011508650 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 538 110.5 2.3e-24 XP_005270849 (OMIM: 142622,224500) PREDICTED: neur ( 193) 538 110.5 2.3e-24 NP_001245288 (OMIM: 600207) hippocalcin-like prote ( 193) 538 110.5 2.3e-24 XP_011508649 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 538 110.5 2.3e-24 NP_602293 (OMIM: 600207) hippocalcin-like protein ( 193) 538 110.5 2.3e-24 NP_002140 (OMIM: 600207) hippocalcin-like protein ( 193) 538 110.5 2.3e-24 >>NP_038462 (OMIM: 604662) calsenilin isoform 1 [Homo sa (256 aa) initn: 1713 init1: 1713 opt: 1713 Z-score: 1740.1 bits: 329.6 E(85289): 3.5e-90 Smith-Waterman score: 1713; 100.0% identity (100.0% similar) in 256 aa overlap (1-256:1-256) 10 20 30 40 50 60 pF1KB7 MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_038 MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_038 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_038 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 YITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_038 YITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQ 190 200 210 220 230 240 250 pF1KB7 KDENIMSSMQLFENVI :::::::::::::::: NP_038 KDENIMSSMQLFENVI 250 >>NP_001030086 (OMIM: 604662) calsenilin isoform 2 precu (230 aa) initn: 1303 init1: 1303 opt: 1303 Z-score: 1327.8 bits: 253.1 E(85289): 3.2e-67 Smith-Waterman score: 1303; 100.0% identity (100.0% similar) in 196 aa overlap (61-256:35-230) 40 50 60 70 80 90 pF1KB7 KWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTK :::::::::::::::::::::::::::::: NP_001 GMELCAMAVVVLLFIAVLKQFGILEPISMEDSSDSELELSTVRHQPEGLDQLQAQTKFTK 10 20 30 40 50 60 100 110 120 130 140 150 pF1KB7 KELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFED 70 80 90 100 110 120 160 170 180 190 200 210 pF1KB7 FVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDA 130 140 150 160 170 180 220 230 240 250 pF1KB7 PAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI :::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI 190 200 210 220 230 >>NP_079497 (OMIM: 608182) Kv channel-interacting protei (250 aa) initn: 1060 init1: 1060 opt: 1074 Z-score: 1096.7 bits: 210.5 E(85289): 2.4e-54 Smith-Waterman score: 1080; 66.9% identity (85.7% similar) in 245 aa overlap (12-256:15-250) 10 20 30 40 50 pF1KB7 MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAP ..: : . .. : :..:: :: . :. : .: ...: NP_079 MNVRRVESISAQLEEASSTGGFLYAQNSTKRSIK---ERLMK--LLPCSAAK----TSSP 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 QGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLI ..: ..:::..::::.::.:. :.::.:::::::: ::::::::::.:.:.:.::: : NP_079 AIQNSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YAQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDIN :.:::::::.::::::::::::.: :::. ::::. ::::::::::.:::.::::::::: NP_079 YSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDIN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 KDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLE ::::::::::: :::.::::::. :::.:.:::: .::: ::.:::.:.::::::.::.: NP_079 KDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIE 180 190 200 210 220 230 240 250 pF1KB7 ACQKDENIMSSMQLFENVI .:::::::: ::::::::: NP_079 SCQKDENIMRSMQLFENVI 240 250 >>NP_001030175 (OMIM: 608182) Kv channel-interacting pro (225 aa) initn: 1068 init1: 1068 opt: 1070 Z-score: 1093.2 bits: 209.7 E(85289): 3.7e-54 Smith-Waterman score: 1070; 71.0% identity (88.8% similar) in 224 aa overlap (34-256:5-225) 10 20 30 40 50 60 pF1KB7 AKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSS-TAPQGSDS : : .:. : .....: :. .:: NP_001 MSGCRKRCKREILK---FAQYLLRLLTGSLHTDS 10 20 30 70 80 90 100 110 120 pF1KB7 SDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFF ..:::..::::.::.:. :.::.:::::::: ::::::::::.:.:.:.::: ::.::: NP_001 VEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFF 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 PQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYI ::::.::::::::::::.: :::. ::::. ::::::::::.:::.:::::::::::::: NP_001 PQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYI 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 TKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKD :::::: :::.::::::. :::.:.:::: .::: ::.:::.:.::::::.::.:.:::: NP_001 TKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKD 160 170 180 190 200 210 250 pF1KB7 ENIMSSMQLFENVI :::: ::::::::: NP_001 ENIMRSMQLFENVI 220 >>NP_671710 (OMIM: 608182) Kv channel-interacting protei (216 aa) initn: 1068 init1: 1068 opt: 1068 Z-score: 1091.4 bits: 209.3 E(85289): 4.7e-54 Smith-Waterman score: 1068; 76.6% identity (93.0% similar) in 201 aa overlap (56-256:16-216) 30 40 50 60 70 80 pF1KB7 KKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQ : . .:: ..:::..::::.::.:. :.:: NP_671 MNVRRVESISAQLEEASSTGDSVEDELEMATVRHRPEALELLEAQ 10 20 30 40 90 100 110 120 130 140 pF1KB7 TKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGA .:::::::: ::::::::::.:.:.:.::: ::.:::::::.::::::::::::.: ::: NP_671 SKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGA 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB7 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPI . ::::. ::::::::::.:::.:::::::::::::::::::: :::.::::::. :::. NP_671 VSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPV 110 120 130 140 150 160 210 220 230 240 250 pF1KB7 LREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI :.:::: .::: ::.:::.:.::::::.::.:.:::::::: ::::::::: NP_671 LKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI 170 180 190 200 210 >>NP_671712 (OMIM: 608182) Kv channel-interacting protei (229 aa) initn: 1066 init1: 1066 opt: 1066 Z-score: 1089.1 bits: 208.9 E(85289): 6.3e-54 Smith-Waterman score: 1066; 78.1% identity (93.9% similar) in 196 aa overlap (61-256:34-229) 40 50 60 70 80 90 pF1KB7 KWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTK :: ..:::..::::.::.:. :.::.:::: NP_671 EGLEMIAVLIVIVLFVKLLEQFGLIEAGLEDSVEDELEMATVRHRPEALELLEAQSKFTK 10 20 30 40 50 60 100 110 120 130 140 150 pF1KB7 KELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFED :::: ::::::::::.:.:.:.::: ::.:::::::.::::::::::::.: :::. ::: NP_671 KELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFED 70 80 90 100 110 120 160 170 180 190 200 210 pF1KB7 FVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDA :. ::::::::::.:::.:::::::::::::::::::: :::.::::::. :::.:.::: NP_671 FIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDA 130 140 150 160 170 180 220 230 240 250 pF1KB7 PAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI : .::: ::.:::.:.::::::.::.:.:::::::: ::::::::: NP_671 PRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI 190 200 210 220 >>XP_005248247 (OMIM: 608182) PREDICTED: Kv channel-inte (233 aa) initn: 1066 init1: 1066 opt: 1066 Z-score: 1089.0 bits: 208.9 E(85289): 6.4e-54 Smith-Waterman score: 1066; 78.1% identity (93.9% similar) in 196 aa overlap (61-256:38-233) 40 50 60 70 80 90 pF1KB7 KWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTK :: ..:::..::::.::.:. :.::.:::: XP_005 SEGLQTVGIVVIICASLKLLHLLGLIDFSEDSVEDELEMATVRHRPEALELLEAQSKFTK 10 20 30 40 50 60 100 110 120 130 140 150 pF1KB7 KELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFED :::: ::::::::::.:.:.:.::: ::.:::::::.::::::::::::.: :::. ::: XP_005 KELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFED 70 80 90 100 110 120 160 170 180 190 200 210 pF1KB7 FVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDA :. ::::::::::.:::.:::::::::::::::::::: :::.::::::. :::.:.::: XP_005 FIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDA 130 140 150 160 170 180 220 230 240 250 pF1KB7 PAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI : .::: ::.:::.:.::::::.::.:.:::::::: ::::::::: XP_005 PRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI 190 200 210 220 230 >>NP_775286 (OMIM: 604661) Kv channel-interacting protei (225 aa) initn: 1035 init1: 1035 opt: 1046 Z-score: 1069.1 bits: 205.2 E(85289): 8.3e-53 Smith-Waterman score: 1046; 69.2% identity (86.6% similar) in 224 aa overlap (35-256:5-225) 10 20 30 40 50 60 pF1KB7 KEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCC--LVKWILSSTAPQGSDS :: :. : . : . . .: .: :: NP_775 MNRCPRRCRSPLGQAARSLYQLVTGSLSP---DS 10 20 30 70 80 90 100 110 120 pF1KB7 SDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFF :.:.::::: :.::::.::: :::::.:::: ::::::::::.:.:.:..:: ::.::: NP_775 VDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFF 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 PQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYI ::::..::: :::::::.. .:.. :::::.:::..::::: ..:.:::::::.:::: : NP_775 PQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCI 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 TKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKD :::::: ::::::::::..::: :::.:: :::: ::.:::::.:::::::::.:.:::: NP_775 TKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKD 160 170 180 190 200 210 250 pF1KB7 ENIMSSMQLFENVI :::: :::::.::: NP_775 ENIMRSMQLFDNVI 220 >>NP_775287 (OMIM: 604661) Kv channel-interacting protei (220 aa) initn: 1043 init1: 1043 opt: 1043 Z-score: 1066.2 bits: 204.6 E(85289): 1.2e-52 Smith-Waterman score: 1043; 73.2% identity (91.2% similar) in 205 aa overlap (52-256:16-220) 30 40 50 60 70 80 pF1KB7 TPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQ :... : .:: :.:.::::: :.::::.: NP_775 MRGQGRKESLSDSRDLDGSYDQLTDSVDDEFELSTVCHRPEGLEQ 10 20 30 40 90 100 110 120 130 140 pF1KB7 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDAD :: :::::.:::: ::::::::::.:.:.:..:: ::.:::::::..::: :::::::.. NP_775 LQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTN 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB7 GNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRH .:.. :::::.:::..::::: ..:.:::::::.:::: ::::::: ::::::::::.. NP_775 HDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKY 110 120 130 140 150 160 210 220 230 240 250 pF1KB7 TYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI ::: :::.:: :::: ::.:::::.:::::::::.:.:::::::: :::::.::: NP_775 TYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMRSMQLFDNVI 170 180 190 200 210 220 >>NP_001030176 (OMIM: 608182) Kv channel-interacting pro (188 aa) initn: 1036 init1: 1036 opt: 1036 Z-score: 1060.0 bits: 203.3 E(85289): 2.7e-52 Smith-Waterman score: 1036; 78.7% identity (94.1% similar) in 188 aa overlap (69-256:1-188) 40 50 60 70 80 90 pF1KB7 RQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYR ..::::.::.:. :.::.:::::::: ::: NP_001 MATVRHRPEALELLEAQSKFTKKELQILYR 10 20 30 100 110 120 130 140 150 pF1KB7 GFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSIL :::::::.:.:.:.::: ::.:::::::.::::::::::::.: :::. ::::. ::::: NP_001 GFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSIL 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB7 LRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERF :::::.:::.:::::::::::::::::::: :::.::::::. :::.:.:::: .::: : NP_001 LRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETF 100 110 120 130 140 150 220 230 240 250 pF1KB7 FEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI :.:::.:.::::::.::.:.:::::::: ::::::::: NP_001 FQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI 160 170 180 256 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:15:50 2016 done: Sat Nov 5 10:15:51 2016 Total Scan time: 6.610 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]