FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7954, 395 aa 1>>>pF1KB7954 395 - 395 aa - 395 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5596+/-0.00121; mu= 7.6508+/- 0.073 mean_var=188.1883+/-38.247, 0's: 0 Z-trim(106.8): 228 B-trim: 0 in 0/53 Lambda= 0.093493 statistics sampled from 8925 (9176) to 8925 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.282), width: 16 Scan time: 3.020 The best scores are: opt bits E(32554) CCDS32239.1 GABPB1 gene_id:2553|Hs108|chr15 ( 395) 2479 347.2 1.6e-95 CCDS45258.1 GABPB1 gene_id:2553|Hs108|chr15 ( 360) 2179 306.7 2.3e-83 CCDS983.1 GABPB2 gene_id:126626|Hs108|chr1 ( 448) 1646 234.9 1.2e-61 CCDS10135.1 GABPB1 gene_id:2553|Hs108|chr15 ( 383) 1327 191.8 9.3e-49 CCDS10136.1 GABPB1 gene_id:2553|Hs108|chr15 ( 348) 1287 186.3 3.7e-47 CCDS81373.1 GABPB2 gene_id:126626|Hs108|chr1 ( 410) 989 146.2 5.2e-35 >>CCDS32239.1 GABPB1 gene_id:2553|Hs108|chr15 (395 aa) initn: 2479 init1: 2479 opt: 2479 Z-score: 1828.4 bits: 347.2 E(32554): 1.6e-95 Smith-Waterman score: 2479; 100.0% identity (100.0% similar) in 395 aa overlap (1-395:1-395) 10 20 30 40 50 60 pF1KB7 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 PQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLSNS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQKQLDEANRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQKQLDEANRE 310 320 330 340 350 360 370 380 390 pF1KB7 AQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV ::::::::::::::::::::::::::::::::::: CCDS32 AQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 370 380 390 >>CCDS45258.1 GABPB1 gene_id:2553|Hs108|chr15 (360 aa) initn: 2397 init1: 2179 opt: 2179 Z-score: 1610.3 bits: 306.7 E(32554): 2.3e-83 Smith-Waterman score: 2179; 99.1% identity (99.1% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KB7 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLSNS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQKQLDEANRE ::::::::::::::::::::::::::::::::::::::::::::: : : CCDS45 MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEVRSLLPGVLCRSHPK 310 320 330 340 350 360 370 380 390 pF1KB7 AQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV >>CCDS983.1 GABPB2 gene_id:126626|Hs108|chr1 (448 aa) initn: 1501 init1: 1072 opt: 1646 Z-score: 1220.5 bits: 234.9 E(32554): 1.2e-61 Smith-Waterman score: 1646; 68.5% identity (86.2% similar) in 400 aa overlap (1-391:1-398) 10 20 30 40 50 60 pF1KB7 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: CCDS98 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: CCDS98 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . CCDS98 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS :.: ::. : ::::..:.:: :.. .. . .:.:::.::.::::::::::::::.::: CCDS98 AAP-FIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLS 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI :: .. .. :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. CCDS98 NSHRA-TANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: CCDS98 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ 300 310 320 330 340 350 360 370 380 390 pF1KB7 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV .::.::::.::.::.:::::::::: :: ::::..: : : CCDS98 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE 360 370 380 390 400 410 CCDS98 GELEERETKVTGSAGTTEPHTRVSMATVSS 420 430 440 >>CCDS10135.1 GABPB1 gene_id:2553|Hs108|chr15 (383 aa) initn: 1325 init1: 1260 opt: 1327 Z-score: 988.8 bits: 191.8 E(32554): 9.3e-49 Smith-Waterman score: 2378; 97.0% identity (97.0% similar) in 395 aa overlap (1-395:1-383) 10 20 30 40 50 60 pF1KB7 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLSNS :::::::::::::: :::::::::::::::::::::::::::::::::: CCDS10 PQFIIGPGGVVNLT------------DETGVSAVQFGNSSTSVLATLAALAEASAPLSNS 190 200 210 220 250 260 270 280 290 300 pF1KB7 SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQKQLDEANRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQKQLDEANRE 290 300 310 320 330 340 370 380 390 pF1KB7 AQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV ::::::::::::::::::::::::::::::::::: CCDS10 AQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV 350 360 370 380 >>CCDS10136.1 GABPB1 gene_id:2553|Hs108|chr15 (348 aa) initn: 2132 init1: 1260 opt: 1287 Z-score: 960.2 bits: 186.3 E(32554): 3.7e-47 Smith-Waterman score: 2078; 95.7% identity (95.7% similar) in 350 aa overlap (1-350:1-338) 10 20 30 40 50 60 pF1KB7 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLSNS :::::::::::::: :::::::::::::::::::::::::::::::::: CCDS10 PQFIIGPGGVVNLT------------DETGVSAVQFGNSSTSVLATLAALAEASAPLSNS 190 200 210 220 250 260 270 280 290 300 pF1KB7 SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQKQLDEANRE ::::::::::::::::::::::::::::::::::::::::::::: : : CCDS10 MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEVRSLLPGVLCRSHPK 290 300 310 320 330 340 370 380 390 pF1KB7 AQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV >>CCDS81373.1 GABPB2 gene_id:126626|Hs108|chr1 (410 aa) initn: 1555 init1: 914 opt: 989 Z-score: 742.1 bits: 146.2 E(32554): 5.2e-35 Smith-Waterman score: 1433; 62.5% identity (77.5% similar) in 400 aa overlap (1-391:1-360) 10 20 30 40 50 60 pF1KB7 MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA ::::::::.:::::: ::::::: :::::::::::::::::::::::::::::.:::::: CCDS81 MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV :::::::::::::::::::..::: :::.:...::::::::::::::::::::..:..:: CCDS81 GVSRDARTKVDRTPLHMAAADGHAHIVELLVRNGADVNAKDMLKMTALHWATERHHRDVV 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVT--IHA :::::::::::. ::: :.::::.....: .. ::: :::::.:.::: . :: . CCDS81 ELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 ATPQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLS :.: ::. : ::::..:.:: :. CCDS81 AAP-FIFTSGEVVNLASLISSTNT------------------------------------ 190 200 240 250 260 270 280 290 pF1KB7 NSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLH-SIPTSGIGQPI .: . :::.. ..:::..::::..::::.::::::::. :::.. ::::.:::::. CCDS81 ---KTTSANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPF 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB7 IVTMPDGQQVLTVPATDIAEETVISEE-----PPAKRQCIEIIENRVE-SAEIEEREALQ :::. :::::::::: .::::::.:: : .:. : : :: : : .::: :: CCDS81 IVTVQDGQQVLTVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQ 270 280 290 300 310 320 360 370 380 390 pF1KB7 KQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV .::.::::.::.::.:::::::::: :: ::::..: : : CCDS81 QQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTE 330 340 350 360 370 380 CCDS81 GELEERETKVTGSAGTTEPHTRVSMATVSS 390 400 410 395 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:50:43 2016 done: Sat Nov 5 19:50:43 2016 Total Scan time: 3.020 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]