FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7956, 395 aa 1>>>pF1KB7956 395 - 395 aa - 395 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6287+/-0.000303; mu= 12.1366+/- 0.019 mean_var=125.0852+/-24.757, 0's: 0 Z-trim(121.0): 112 B-trim: 1105 in 2/57 Lambda= 0.114676 statistics sampled from 36968 (37096) to 36968 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.435), width: 16 Scan time: 10.360 The best scores are: opt bits E(85289) NP_001242908 (OMIM: 607138) cyclic AMP-responsive ( 395) 2638 447.2 3.3e-125 NP_001242907 (OMIM: 607138) cyclic AMP-responsive ( 395) 2638 447.2 3.3e-125 NP_570968 (OMIM: 607138) cyclic AMP-responsive ele ( 395) 2638 447.2 3.3e-125 NP_001242910 (OMIM: 607138) cyclic AMP-responsive ( 375) 2212 376.7 5.2e-104 XP_006711235 (OMIM: 607138) PREDICTED: cyclic AMP- ( 375) 2212 376.7 5.2e-104 XP_016855861 (OMIM: 607138) PREDICTED: cyclic AMP- ( 375) 2212 376.7 5.2e-104 NP_001242909 (OMIM: 607138) cyclic AMP-responsive ( 375) 2212 376.7 5.2e-104 NP_001258925 (OMIM: 611998) cyclic AMP-responsive ( 459) 671 121.8 3.4e-27 NP_001258924 (OMIM: 611998) cyclic AMP-responsive ( 460) 671 121.8 3.4e-27 NP_115996 (OMIM: 611998) cyclic AMP-responsive ele ( 461) 671 121.8 3.4e-27 NP_006359 (OMIM: 606443) cyclic AMP-responsive ele ( 371) 519 96.6 1.1e-19 XP_005250598 (OMIM: 608834) PREDICTED: cyclic AMP- ( 457) 429 81.7 3.8e-15 NP_001305175 (OMIM: 608834) cyclic AMP-responsive ( 457) 429 81.7 3.8e-15 XP_016868029 (OMIM: 608834) PREDICTED: cyclic AMP- ( 457) 429 81.7 3.8e-15 XP_016868030 (OMIM: 608834) PREDICTED: cyclic AMP- ( 457) 429 81.7 3.8e-15 NP_919047 (OMIM: 608834) cyclic AMP-responsive ele ( 520) 429 81.8 4.2e-15 NP_443086 (OMIM: 616215) cyclic AMP-responsive ele ( 519) 415 79.5 2.1e-14 XP_006718443 (OMIM: 616215) PREDICTED: cyclic AMP- ( 363) 326 64.6 4.3e-10 NP_001129625 (OMIM: 600984) cyclic AMP-dependent t ( 700) 198 43.7 0.0017 NP_004372 (OMIM: 600984) cyclic AMP-dependent tran ( 703) 198 43.7 0.0017 >>NP_001242908 (OMIM: 607138) cyclic AMP-responsive elem (395 aa) initn: 2638 init1: 2638 opt: 2638 Z-score: 2368.9 bits: 447.2 E(85289): 3.3e-125 Smith-Waterman score: 2638; 99.7% identity (99.7% similar) in 395 aa overlap (1-395:1-395) 10 20 30 40 50 60 pF1KB7 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDSCHPDSPPAPRATSSPMLYEVVYEAG :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDPCHPDSPPAPRATSSPMLYEVVYEAG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP 310 320 330 340 350 360 370 380 390 pF1KB7 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM ::::::::::::::::::::::::::::::::::: NP_001 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM 370 380 390 >>NP_001242907 (OMIM: 607138) cyclic AMP-responsive elem (395 aa) initn: 2638 init1: 2638 opt: 2638 Z-score: 2368.9 bits: 447.2 E(85289): 3.3e-125 Smith-Waterman score: 2638; 99.7% identity (99.7% similar) in 395 aa overlap (1-395:1-395) 10 20 30 40 50 60 pF1KB7 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDSCHPDSPPAPRATSSPMLYEVVYEAG :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDPCHPDSPPAPRATSSPMLYEVVYEAG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP 310 320 330 340 350 360 370 380 390 pF1KB7 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM ::::::::::::::::::::::::::::::::::: NP_001 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM 370 380 390 >>NP_570968 (OMIM: 607138) cyclic AMP-responsive element (395 aa) initn: 2638 init1: 2638 opt: 2638 Z-score: 2368.9 bits: 447.2 E(85289): 3.3e-125 Smith-Waterman score: 2638; 99.7% identity (99.7% similar) in 395 aa overlap (1-395:1-395) 10 20 30 40 50 60 pF1KB7 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDSCHPDSPPAPRATSSPMLYEVVYEAG :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_570 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDPCHPDSPPAPRATSSPMLYEVVYEAG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP 310 320 330 340 350 360 370 380 390 pF1KB7 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM ::::::::::::::::::::::::::::::::::: NP_570 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM 370 380 390 >>NP_001242910 (OMIM: 607138) cyclic AMP-responsive elem (375 aa) initn: 2476 init1: 2212 opt: 2212 Z-score: 1988.3 bits: 376.7 E(85289): 5.2e-104 Smith-Waterman score: 2440; 94.7% identity (94.7% similar) in 395 aa overlap (1-395:1-375) 10 20 30 40 50 60 pF1KB7 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL :::::::::::::::::::::::::::::::::::::: :: NP_001 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVP--------------------GL 10 20 30 40 70 80 90 100 110 120 pF1KB7 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDSCHPDSPPAPRATSSPMLYEVVYEAG :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDPCHPDSPPAPRATSSPMLYEVVYEAG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP 290 300 310 320 330 340 370 380 390 pF1KB7 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM ::::::::::::::::::::::::::::::::::: NP_001 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM 350 360 370 >>XP_006711235 (OMIM: 607138) PREDICTED: cyclic AMP-resp (375 aa) initn: 2476 init1: 2212 opt: 2212 Z-score: 1988.3 bits: 376.7 E(85289): 5.2e-104 Smith-Waterman score: 2440; 94.7% identity (94.7% similar) in 395 aa overlap (1-395:1-375) 10 20 30 40 50 60 pF1KB7 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL :::::::::::::::::::::::::::::::::::::: :: XP_006 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVP--------------------GL 10 20 30 40 70 80 90 100 110 120 pF1KB7 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDSCHPDSPPAPRATSSPMLYEVVYEAG :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_006 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDPCHPDSPPAPRATSSPMLYEVVYEAG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP 290 300 310 320 330 340 370 380 390 pF1KB7 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM ::::::::::::::::::::::::::::::::::: XP_006 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM 350 360 370 >>XP_016855861 (OMIM: 607138) PREDICTED: cyclic AMP-resp (375 aa) initn: 2476 init1: 2212 opt: 2212 Z-score: 1988.3 bits: 376.7 E(85289): 5.2e-104 Smith-Waterman score: 2440; 94.7% identity (94.7% similar) in 395 aa overlap (1-395:1-375) 10 20 30 40 50 60 pF1KB7 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL :::::::::::::::::::::::::::::::::::::: :: XP_016 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVP--------------------GL 10 20 30 40 70 80 90 100 110 120 pF1KB7 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDSCHPDSPPAPRATSSPMLYEVVYEAG :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_016 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDPCHPDSPPAPRATSSPMLYEVVYEAG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP 290 300 310 320 330 340 370 380 390 pF1KB7 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM ::::::::::::::::::::::::::::::::::: XP_016 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM 350 360 370 >>NP_001242909 (OMIM: 607138) cyclic AMP-responsive elem (375 aa) initn: 2476 init1: 2212 opt: 2212 Z-score: 1988.3 bits: 376.7 E(85289): 5.2e-104 Smith-Waterman score: 2440; 94.7% identity (94.7% similar) in 395 aa overlap (1-395:1-375) 10 20 30 40 50 60 pF1KB7 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGL :::::::::::::::::::::::::::::::::::::: :: NP_001 MDLGIPDLLDAWLEPPEDIFSTGSVLELGLHCPPPEVP--------------------GL 10 20 30 40 70 80 90 100 110 120 pF1KB7 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDSCHPDSPPAPRATSSPMLYEVVYEAG :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 QESEPEDFLKLFIDPNEVYCSEASPGSDSGISEDPCHPDSPPAPRATSSPMLYEVVYEAG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALERMQGETGPNVGLISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPRAGTVAPVPCTT 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLPCQTLFLTDEEKRLLGQEGVSLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDGLESRVAACSAQNQELQKKVQELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPP 290 300 310 320 330 340 370 380 390 pF1KB7 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM ::::::::::::::::::::::::::::::::::: NP_001 GAKDANGSTRTLLEKMGGKPRPSGRIRSVLHADEM 350 360 370 >>NP_001258925 (OMIM: 611998) cyclic AMP-responsive elem (459 aa) initn: 689 init1: 640 opt: 671 Z-score: 609.3 bits: 121.8 E(85289): 3.4e-27 Smith-Waterman score: 746; 40.3% identity (64.2% similar) in 377 aa overlap (39-380:36-397) 10 20 30 40 50 60 pF1KB7 LDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGLQESEPEDF . : : : .:: :. : . . .:: NP_001 AAGKMASAACSMDPIDSFELLDLLFDRQDGILRHVELG-EGWGHVKDQQV-LPNPDSDDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LKLFIDPNEVYCSEA--SP-GSDSGISED--SCHPDSPPAPRATSSPMLYEVVY--EAGA :. .. .. : :: ::::::::: : :.:: ..:: . . .. NP_001 LSSILGSGDSLPSSPLWSPEGSDSGISEDLPSDPQDTPPRSGPATSPAGCHPAQPGKGPC 70 80 90 100 110 120 130 140 150 160 pF1KB7 LERMQGET------GPNVGL----ISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPR-- : :.. :: . . ..:.:..:::. . : .: : : . . :: NP_001 LSYHPGNSCSTTTPGPVIQVPEASVTIDLEMWSPGGRI---C--AEKPADP-VDLSPRCN 130 140 150 160 170 170 180 190 200 210 pF1KB7 -----------AGTVAPVPCTTLL-P----CQTLFLTDEEKRLLGQEGVSLPSHLPLTKA .: . . . :: : :: : ::..::.::..::..::..::::: NP_001 LTVKDLLLSGSSGDLHHLGASYLLRPGAGHCQELVLTEDEKKLLAKEGITLPTQLPLTKY 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 EERVLKKVRRKIRNKQSAQDSRRRKKEYIDGLESRVAACSAQNQELQKKVQELERHNISL :::::::.:::::::::::.::..:::::::::.:..::.:::::::.:: .::..:.:: NP_001 EERVLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNLSL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 VAQLRQLQTLIAQTSNKAAQTSTCVLILLFSLALIILPSFSPFQSRPEAGSEDYQPHGVT . ::..::....:...:.:::.::: .::.:.:::::::.::: . :. : : NP_001 LEQLKKLQAIVVQSTSKSAQTGTCVAVLLLSFALIILPSISPFGPNKTESPGDFAPVRVF 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB7 SRNILTHKDVTENLETQVVESRLREPPGAKDANGSTRTLLEKMGGKPRPSGRIRSVLHAD ::.. :.:.. . ...: . : :: . .:: :. :.: NP_001 SRTL--HNDAASRVAADAVPGS--EAPGPRPEADTTR---EESPGSPGADWGFQDTANLT 360 370 380 390 400 410 pF1KB7 EM NP_001 NSTEELDNATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGLEAAGDEL 420 430 440 450 >>NP_001258924 (OMIM: 611998) cyclic AMP-responsive elem (460 aa) initn: 689 init1: 640 opt: 671 Z-score: 609.3 bits: 121.8 E(85289): 3.4e-27 Smith-Waterman score: 734; 40.1% identity (64.1% similar) in 379 aa overlap (39-380:36-398) 10 20 30 40 50 60 pF1KB7 LDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGLQESEPEDF . : : : .:: : . : . . .:: NP_001 AAGKMASAACSMDPIDSFELLDLLFDRQDGILRHVELG-EGW--GHVKDQVLPNPDSDDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LKLFIDPNEVYCSEA--SP-GSDSGISED--SCHPDSPPAPRATSSPMLYEVVY--EAGA :. .. .. : :: ::::::::: : :.:: ..:: . . .. NP_001 LSSILGSGDSLPSSPLWSPEGSDSGISEDLPSDPQDTPPRSGPATSPAGCHPAQPGKGPC 70 80 90 100 110 120 130 140 150 160 pF1KB7 LERMQGET------GPNVGL----ISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPR-- : :.. :: . . ..:.:..:::. . : .: : : . . :: NP_001 LSYHPGNSCSTTTPGPVIQVPEASVTIDLEMWSPGGRI---C--AEKPADP-VDLSPRCN 130 140 150 160 170 170 180 190 200 210 pF1KB7 --------AGTVAPVP-----CTTLL-P----CQTLFLTDEEKRLLGQEGVSLPSHLPLT .:. . . . :: : :: : ::..::.::..::..::..:::: NP_001 LTVKDLLLSGSSGDLQQHHLGASYLLRPGAGHCQELVLTEDEKKLLAKEGITLPTQLPLT 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 KAEERVLKKVRRKIRNKQSAQDSRRRKKEYIDGLESRVAACSAQNQELQKKVQELERHNI : :::::::.:::::::::::.::..:::::::::.:..::.:::::::.:: .::..:. NP_001 KYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 SLVAQLRQLQTLIAQTSNKAAQTSTCVLILLFSLALIILPSFSPFQSRPEAGSEDYQPHG ::. ::..::....:...:.:::.::: .::.:.:::::::.::: . :. : NP_001 SLLEQLKKLQAIVVQSTSKSAQTGTCVAVLLLSFALIILPSISPFGPNKTESPGDFAPVR 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB7 VTSRNILTHKDVTENLETQVVESRLREPPGAKDANGSTRTLLEKMGGKPRPSGRIRSVLH : ::.. :.:.. . ...: . : :: . .:: :. :.: NP_001 VFSRTL--HNDAASRVAADAVPGS--EAPGPRPEADTTR---EESPGSPGADWGFQDTAN 360 370 380 390 400 pF1KB7 ADEM NP_001 LTNSTEELDNATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGLEAAGDEL 410 420 430 440 450 460 >>NP_115996 (OMIM: 611998) cyclic AMP-responsive element (461 aa) initn: 689 init1: 640 opt: 671 Z-score: 609.2 bits: 121.8 E(85289): 3.4e-27 Smith-Waterman score: 736; 40.1% identity (64.1% similar) in 379 aa overlap (39-380:36-399) 10 20 30 40 50 60 pF1KB7 LDAWLEPPEDIFSTGSVLELGLHCPPPEVPVTRLQEQGLQGWKSGGDRGCGLQESEPEDF . : : : .:: :. : . . .:: NP_115 AAGKMASAACSMDPIDSFELLDLLFDRQDGILRHVELG-EGWGHVKDQQV-LPNPDSDDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LKLFIDPNEVYCSEA--SP-GSDSGISED--SCHPDSPPAPRATSSPMLYEVVY--EAGA :. .. .. : :: ::::::::: : :.:: ..:: . . .. NP_115 LSSILGSGDSLPSSPLWSPEGSDSGISEDLPSDPQDTPPRSGPATSPAGCHPAQPGKGPC 70 80 90 100 110 120 130 140 150 160 pF1KB7 LERMQGET------GPNVGL----ISIQLDQWSPAFMVPDSCMVSELPFDAHAHILPR-- : :.. :: . . ..:.:..:::. . : .: : : . . :: NP_115 LSYHPGNSCSTTTPGPVIQVPEASVTIDLEMWSPGGRI---C--AEKPADP-VDLSPRCN 130 140 150 160 170 170 180 190 200 210 pF1KB7 --------AGTVAPVP-----CTTLL-P----CQTLFLTDEEKRLLGQEGVSLPSHLPLT .:. . . . :: : :: : ::..::.::..::..::..:::: NP_115 LTVKDLLLSGSSGDLQQHHLGASYLLRPGAGHCQELVLTEDEKKLLAKEGITLPTQLPLT 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 KAEERVLKKVRRKIRNKQSAQDSRRRKKEYIDGLESRVAACSAQNQELQKKVQELERHNI : :::::::.:::::::::::.::..:::::::::.:..::.:::::::.:: .::..:. NP_115 KYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 SLVAQLRQLQTLIAQTSNKAAQTSTCVLILLFSLALIILPSFSPFQSRPEAGSEDYQPHG ::. ::..::....:...:.:::.::: .::.:.:::::::.::: . :. : NP_115 SLLEQLKKLQAIVVQSTSKSAQTGTCVAVLLLSFALIILPSISPFGPNKTESPGDFAPVR 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB7 VTSRNILTHKDVTENLETQVVESRLREPPGAKDANGSTRTLLEKMGGKPRPSGRIRSVLH : ::.. :.:.. . ...: . : :: . .:: :. :.: NP_115 VFSRTL--HNDAASRVAADAVPGS--EAPGPRPEADTTR---EESPGSPGADWGFQDTAN 360 370 380 390 400 410 pF1KB7 ADEM NP_115 LTNSTEELDNATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGLEAAGDEL 420 430 440 450 460 395 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:44:24 2016 done: Sat Nov 5 14:44:25 2016 Total Scan time: 10.360 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]