FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7957, 261 aa 1>>>pF1KB7957 261 - 261 aa - 261 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9790+/-0.00029; mu= 11.7377+/- 0.018 mean_var=102.5519+/-21.362, 0's: 0 Z-trim(120.1): 243 B-trim: 422 in 1/56 Lambda= 0.126649 statistics sampled from 34482 (34832) to 34482 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.408), width: 16 Scan time: 6.600 The best scores are: opt bits E(85289) NP_115590 (OMIM: 606577) src-like-adapter 2 isofor ( 261) 1739 327.7 1.3e-89 NP_778252 (OMIM: 606577) src-like-adapter 2 isofor ( 210) 1204 229.9 3e-60 XP_016883587 (OMIM: 606577) PREDICTED: src-like-ad ( 288) 1189 227.2 2.5e-59 NP_001039022 (OMIM: 601099) src-like-adapter isofo ( 293) 644 127.7 2.4e-29 NP_006739 (OMIM: 601099) src-like-adapter isoform ( 316) 644 127.7 2.6e-29 NP_001039021 (OMIM: 601099) src-like-adapter isofo ( 276) 630 125.1 1.4e-28 XP_016868905 (OMIM: 165120) PREDICTED: tyrosine-pr ( 491) 493 100.3 7.2e-21 NP_001104567 (OMIM: 165120) tyrosine-protein kinas ( 491) 493 100.3 7.2e-21 NP_002341 (OMIM: 165120) tyrosine-protein kinase L ( 512) 493 100.3 7.4e-21 XP_016868904 (OMIM: 165120) PREDICTED: tyrosine-pr ( 499) 490 99.7 1.1e-20 XP_011515831 (OMIM: 165120) PREDICTED: tyrosine-pr ( 682) 490 99.8 1.4e-20 NP_001165600 (OMIM: 142370) tyrosine-protein kinas ( 505) 481 98.1 3.4e-20 NP_001165604 (OMIM: 142370) tyrosine-protein kinas ( 505) 481 98.1 3.4e-20 NP_001165603 (OMIM: 142370) tyrosine-protein kinas ( 506) 481 98.1 3.4e-20 NP_002101 (OMIM: 142370) tyrosine-protein kinase H ( 526) 481 98.1 3.5e-20 XP_011542131 (OMIM: 191305,613375) PREDICTED: tyro ( 344) 470 95.9 1e-19 XP_011542130 (OMIM: 191305,613375) PREDICTED: tyro ( 345) 470 95.9 1e-19 NP_001165602 (OMIM: 142370) tyrosine-protein kinas ( 504) 470 96.1 1.4e-19 NP_001706 (OMIM: 191305,613375) tyrosine-protein k ( 505) 470 96.1 1.4e-19 NP_001165601 (OMIM: 142370) tyrosine-protein kinas ( 525) 470 96.1 1.4e-19 XP_011542127 (OMIM: 191305,613375) PREDICTED: tyro ( 531) 470 96.1 1.4e-19 XP_011542126 (OMIM: 191305,613375) PREDICTED: tyro ( 531) 470 96.1 1.4e-19 NP_001036236 (OMIM: 153390,615758) tyrosine-protei ( 509) 452 92.8 1.3e-18 NP_005347 (OMIM: 153390,615758) tyrosine-protein k ( 509) 452 92.8 1.3e-18 NP_001317394 (OMIM: 191305,613375) tyrosine-protei ( 434) 450 92.4 1.5e-18 XP_011542129 (OMIM: 191305,613375) PREDICTED: tyro ( 460) 450 92.4 1.6e-18 XP_011539315 (OMIM: 164940) PREDICTED: tyrosine-pr ( 352) 427 88.1 2.4e-17 XP_011539314 (OMIM: 164940) PREDICTED: tyrosine-pr ( 410) 427 88.1 2.7e-17 NP_005239 (OMIM: 164940) tyrosine-protein kinase F ( 529) 427 88.2 3.3e-17 XP_011539312 (OMIM: 164940) PREDICTED: tyrosine-pr ( 529) 427 88.2 3.3e-17 NP_001036194 (OMIM: 164940) tyrosine-protein kinas ( 529) 427 88.2 3.3e-17 NP_001036212 (OMIM: 164940) tyrosine-protein kinas ( 529) 427 88.2 3.3e-17 XP_006710515 (OMIM: 164940) PREDICTED: tyrosine-pr ( 529) 427 88.2 3.3e-17 XP_016866144 (OMIM: 137025) PREDICTED: tyrosine-pr ( 311) 421 86.9 4.7e-17 XP_016866139 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17 NP_002028 (OMIM: 137025) tyrosine-protein kinase F ( 537) 421 87.1 7e-17 XP_016866141 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17 XP_016866143 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17 XP_016866142 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17 XP_016866140 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17 NP_694592 (OMIM: 137025) tyrosine-protein kinase F ( 534) 406 84.4 4.7e-16 XP_005266947 (OMIM: 137025) PREDICTED: tyrosine-pr ( 534) 406 84.4 4.7e-16 XP_005258196 (OMIM: 164880) PREDICTED: tyrosine-pr ( 499) 405 84.2 5.1e-16 NP_005424 (OMIM: 164880) tyrosine-protein kinase Y ( 543) 405 84.2 5.4e-16 XP_016881449 (OMIM: 164880) PREDICTED: tyrosine-pr ( 543) 405 84.2 5.4e-16 NP_001317397 (OMIM: 153390,615758) tyrosine-protei ( 458) 401 83.4 7.9e-16 XP_011539756 (OMIM: 153390,615758) PREDICTED: tyro ( 516) 401 83.5 8.6e-16 XP_011539755 (OMIM: 153390,615758) PREDICTED: tyro ( 516) 401 83.5 8.6e-16 XP_016869228 (OMIM: 601099) PREDICTED: src-like-ad ( 168) 366 76.7 3.1e-14 NP_001269894 (OMIM: 601099) src-like-adapter isofo ( 168) 366 76.7 3.1e-14 >>NP_115590 (OMIM: 606577) src-like-adapter 2 isoform a (261 aa) initn: 1739 init1: 1739 opt: 1739 Z-score: 1729.8 bits: 327.7 E(85289): 1.3e-89 Smith-Waterman score: 1739; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261) 10 20 30 40 50 60 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 DDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEG 190 200 210 220 230 240 250 260 pF1KB7 LRESLSFYISLNDEAVSLDDA ::::::::::::::::::::: NP_115 LRESLSFYISLNDEAVSLDDA 250 260 >>NP_778252 (OMIM: 606577) src-like-adapter 2 isoform b (210 aa) initn: 1220 init1: 1193 opt: 1204 Z-score: 1202.7 bits: 229.9 E(85289): 3e-60 Smith-Waterman score: 1204; 89.4% identity (90.8% similar) in 207 aa overlap (1-200:1-207) 10 20 30 40 50 60 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_778 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_778 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSEL- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_778 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSEGW 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 ------ADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGE : .. :.::: :: NP_778 PAPWQGYTPTCDCAEDTTQLERAGQLPPVF 190 200 210 >>XP_016883587 (OMIM: 606577) PREDICTED: src-like-adapte (288 aa) initn: 1213 init1: 1189 opt: 1189 Z-score: 1186.1 bits: 227.2 E(85289): 2.5e-59 Smith-Waterman score: 1189; 99.4% identity (100.0% similar) in 178 aa overlap (1-178:1-178) 10 20 30 40 50 60 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSDRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEG XP_016 KSGLPYFHASPYAKKCRLGALSSPRALAEKPQTSCVGSGQYLAYHSGSDSEPLAAGRVLS 190 200 210 220 230 240 >>NP_001039022 (OMIM: 601099) src-like-adapter isoform b (293 aa) initn: 631 init1: 334 opt: 644 Z-score: 647.8 bits: 127.7 E(85289): 2.4e-29 Smith-Waterman score: 644; 41.8% identity (67.8% similar) in 261 aa overlap (5-259:12-265) 10 20 30 40 50 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTM-EAERSKATAVALGSFPAGGPAELS :...: . . :. . .. :. :. : :: :...:. . NP_001 MLHRLWASPAAPGKKKEMGNSMKSTPAPAERPLPNPEGLDSDFLAV-LSDYPSPDISPPI 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPG .: :: : ..:..: :: ..: .::: ::.. ::.: ::::.:::.:.:::::: :: NP_001 FRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 NPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQAL . :.:.::::.:..: :::::: . ..:::: : :.: :::::::: :. : NP_001 TKVGSFMIRESETKKGFYSLSVRHRQ------VKHYRIFRLPNNWYYISPRLTFQCLEDL 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 VDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKE---LDSSLLFSEA :.::::.:: .::.: ::. : .. . :::... ..:.. :. . .: NP_001 VNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTEN 180 190 200 210 220 230 230 240 250 260 pF1KB7 ATG-EESLLSEGLRESLSFYISLNDE-AVSLDDA : .:::.: :::::.. :.::..: .:.: NP_001 PLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 240 250 260 270 280 290 >>NP_006739 (OMIM: 601099) src-like-adapter isoform c [H (316 aa) initn: 650 init1: 334 opt: 644 Z-score: 647.3 bits: 127.7 E(85289): 2.6e-29 Smith-Waterman score: 644; 41.8% identity (67.8% similar) in 261 aa overlap (5-259:35-288) 10 20 30 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTM-EAERS :...: . . :. . .. :. :. : NP_006 LGHSPLGGLRARLTFPVCLLYHRLWASPAAPGKKKEMGNSMKSTPAPAERPLPNPEGLDS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 KATAVALGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHG :: :...:. . .: :: : ..:..: :: ..: .::: ::.. ::.: :: NP_006 DFLAV-LSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCL ::.:::.:.:::::: :: . :.:.::::.:..: :::::: . ..:::: : NP_006 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQ------VKHYRIFRL 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRT :.: :::::::: :. ::.::::.:: .::.: ::. : .. . :::... NP_006 PNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQK 180 190 200 210 220 230 220 230 240 250 260 pF1KB7 PLNWKE---LDSSLLFSEAATG-EESLLSEGLRESLSFYISLNDE-AVSLDDA ..:.. :. . .: : .:::.: :::::.. :.::..: .:.: NP_006 TVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLM 240 250 260 270 280 290 NP_006 YGGSKRKSSFFSSPPYFED 300 310 >>NP_001039021 (OMIM: 601099) src-like-adapter isoform a (276 aa) initn: 651 init1: 334 opt: 630 Z-score: 634.3 bits: 125.1 E(85289): 1.4e-28 Smith-Waterman score: 630; 42.8% identity (66.9% similar) in 257 aa overlap (9-259:6-248) 10 20 30 40 50 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTM-EAERSKATAVALGSFPAGGPAELSLRLGEPL :: :.:. . :. :. : :: :...:. . .: :: : NP_001 MGNSMKSTPAPA-------ERPLPNPEGLDSDFLAV-LSDYPSPDISPPIFRRGEKL 10 20 30 40 60 70 80 90 100 110 pF1KB7 TIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFL ..:..: :: ..: .::: ::.. ::.: ::::.:::.:.:::::: :: . :.:. NP_001 RVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFM 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 IRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSEL ::::.:..: :::::: . ..:::: : :.: :::::::: :. ::.::::. NP_001 IRESETKKGFYSLSVRHRQ------VKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEV 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 ADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKE---LDSSLLFSEAATG-EES :: .::.: ::. : .. . :::... ..:.. :. . .: : .:: NP_001 ADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDES 170 180 190 200 210 220 240 250 260 pF1KB7 LLSEGLRESLSFYISLNDE-AVSLDDA :.: :::::.. :.::..: .:.: NP_001 LFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 230 240 250 260 270 >>XP_016868905 (OMIM: 165120) PREDICTED: tyrosine-protei (491 aa) initn: 485 init1: 356 opt: 493 Z-score: 495.6 bits: 100.3 E(85289): 7.2e-21 Smith-Waterman score: 493; 40.9% identity (66.7% similar) in 198 aa overlap (9-202:20-212) 10 20 30 40 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPA :. : : :. . :: : . :.. .::: . . : XP_016 MGCIKSKGKDSLSDDGVDLKTQPVPE-SQLLPGQRFQTKDPEEQGDIVVALYPYDGIHPD 10 20 30 40 50 50 60 70 80 90 100 pF1KB7 ELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKV----SHGWLYEGLSREKAE .::.. :: . .. : :.:: . : .. .: ::: .:::. .. :... ..:. :: XP_016 DLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAE 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 ELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLT . :: ::: .::::::::.: .::.::::: :. : :.::.:. :::: :::::.: XP_016 RQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRIT 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 FPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLL :: .. .. ::.. :: .: :.. :. .: : : XP_016 FPCISDMIKHYQKQADGLCRRLEKACI----SPKPQKPWDKDAWEIPRESIKLVKRLGAG 180 190 200 210 220 230 230 240 250 260 pF1KB7 FSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA XP_016 QFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIY 240 250 260 270 280 290 >>NP_001104567 (OMIM: 165120) tyrosine-protein kinase Ly (491 aa) initn: 485 init1: 356 opt: 493 Z-score: 495.6 bits: 100.3 E(85289): 7.2e-21 Smith-Waterman score: 493; 40.9% identity (66.7% similar) in 198 aa overlap (9-202:20-212) 10 20 30 40 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPA :. : : :. . :: : . :.. .::: . . : NP_001 MGCIKSKGKDSLSDDGVDLKTQPVPE-SQLLPGQRFQTKDPEEQGDIVVALYPYDGIHPD 10 20 30 40 50 50 60 70 80 90 100 pF1KB7 ELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKV----SHGWLYEGLSREKAE .::.. :: . .. : :.:: . : .. .: ::: .:::. .. :... ..:. :: NP_001 DLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAE 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 ELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLT . :: ::: .::::::::.: .::.::::: :. : :.::.:. :::: :::::.: NP_001 RQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRIT 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 FPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLL :: .. .. ::.. :: .: :.. :. .: : : NP_001 FPCISDMIKHYQKQADGLCRRLEKACI----SPKPQKPWDKDAWEIPRESIKLVKRLGAG 180 190 200 210 220 230 230 240 250 260 pF1KB7 FSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA NP_001 QFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIY 240 250 260 270 280 290 >>NP_002341 (OMIM: 165120) tyrosine-protein kinase Lyn i (512 aa) initn: 485 init1: 356 opt: 493 Z-score: 495.4 bits: 100.3 E(85289): 7.4e-21 Smith-Waterman score: 493; 40.3% identity (66.7% similar) in 201 aa overlap (6-202:38-233) 10 20 30 pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKA : ... : : :. . :: : . :.. NP_002 GKDSLSDDGVDLKTQPVRNTERTIYVRDPTSNKQQRPVPE-SQLLPGQRFQTKDPEEQGD 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 TAVALGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKV----S .::: . . : .::.. :: . .. : :.:: . : .. .: ::: .:::. . NP_002 IVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLET 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 HGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIH . :... ..:. ::. :: ::: .::::::::.: .::.::::: :. : :.::.:. NP_002 EEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 CLDNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQ :::: :::::.::: .. .. ::.. :: .: :.. :. .: : : NP_002 SLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACI----SPKPQKPWDKDAWEI 190 200 210 220 230 240 220 230 240 250 260 pF1KB7 RTPLNWKELDSSLLFSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA NP_002 PRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKL 250 260 270 280 290 300 >>XP_016868904 (OMIM: 165120) PREDICTED: tyrosine-protei (499 aa) initn: 485 init1: 356 opt: 490 Z-score: 492.6 bits: 99.7 E(85289): 1.1e-20 Smith-Waterman score: 490; 39.9% identity (65.4% similar) in 208 aa overlap (2-202:203-403) 10 20 pF1KB7 MGSLPSR---RKSLPSPSLSSSVQGQGPVTM :. : : :. .: .: . :: : XP_016 ASSVPGQQPPHTQVLLGRPVAPPTLNSSHRGAPPPRNFHRERVPESQL---LPGQRFQTK 180 190 200 210 220 30 40 50 60 70 80 pF1KB7 EAERSKATAVALGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVA . :.. .::: . . : .::.. :: . .. : :.:: . : .. .: ::: .:: XP_016 DPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVA 230 240 250 260 270 280 90 100 110 120 130 140 pF1KB7 KV----SHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDR :. .. :... ..:. ::. :: ::: .::::::::.: .::.::::: :. : XP_016 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 290 300 310 320 330 340 150 160 170 180 190 200 pF1KB7 IRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDI :.::.:. :::: :::::.::: .. .. ::.. :: .: :.. :. .: : : XP_016 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACI----SPKPQKPW 350 360 370 380 390 400 210 220 230 240 250 260 pF1KB7 PLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA XP_016 DKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMK 410 420 430 440 450 460 261 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:44:54 2016 done: Sat Nov 5 14:44:55 2016 Total Scan time: 6.600 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]