FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7957, 261 aa
1>>>pF1KB7957 261 - 261 aa - 261 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9790+/-0.00029; mu= 11.7377+/- 0.018
mean_var=102.5519+/-21.362, 0's: 0 Z-trim(120.1): 243 B-trim: 422 in 1/56
Lambda= 0.126649
statistics sampled from 34482 (34832) to 34482 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.408), width: 16
Scan time: 6.600
The best scores are: opt bits E(85289)
NP_115590 (OMIM: 606577) src-like-adapter 2 isofor ( 261) 1739 327.7 1.3e-89
NP_778252 (OMIM: 606577) src-like-adapter 2 isofor ( 210) 1204 229.9 3e-60
XP_016883587 (OMIM: 606577) PREDICTED: src-like-ad ( 288) 1189 227.2 2.5e-59
NP_001039022 (OMIM: 601099) src-like-adapter isofo ( 293) 644 127.7 2.4e-29
NP_006739 (OMIM: 601099) src-like-adapter isoform ( 316) 644 127.7 2.6e-29
NP_001039021 (OMIM: 601099) src-like-adapter isofo ( 276) 630 125.1 1.4e-28
XP_016868905 (OMIM: 165120) PREDICTED: tyrosine-pr ( 491) 493 100.3 7.2e-21
NP_001104567 (OMIM: 165120) tyrosine-protein kinas ( 491) 493 100.3 7.2e-21
NP_002341 (OMIM: 165120) tyrosine-protein kinase L ( 512) 493 100.3 7.4e-21
XP_016868904 (OMIM: 165120) PREDICTED: tyrosine-pr ( 499) 490 99.7 1.1e-20
XP_011515831 (OMIM: 165120) PREDICTED: tyrosine-pr ( 682) 490 99.8 1.4e-20
NP_001165600 (OMIM: 142370) tyrosine-protein kinas ( 505) 481 98.1 3.4e-20
NP_001165604 (OMIM: 142370) tyrosine-protein kinas ( 505) 481 98.1 3.4e-20
NP_001165603 (OMIM: 142370) tyrosine-protein kinas ( 506) 481 98.1 3.4e-20
NP_002101 (OMIM: 142370) tyrosine-protein kinase H ( 526) 481 98.1 3.5e-20
XP_011542131 (OMIM: 191305,613375) PREDICTED: tyro ( 344) 470 95.9 1e-19
XP_011542130 (OMIM: 191305,613375) PREDICTED: tyro ( 345) 470 95.9 1e-19
NP_001165602 (OMIM: 142370) tyrosine-protein kinas ( 504) 470 96.1 1.4e-19
NP_001706 (OMIM: 191305,613375) tyrosine-protein k ( 505) 470 96.1 1.4e-19
NP_001165601 (OMIM: 142370) tyrosine-protein kinas ( 525) 470 96.1 1.4e-19
XP_011542127 (OMIM: 191305,613375) PREDICTED: tyro ( 531) 470 96.1 1.4e-19
XP_011542126 (OMIM: 191305,613375) PREDICTED: tyro ( 531) 470 96.1 1.4e-19
NP_001036236 (OMIM: 153390,615758) tyrosine-protei ( 509) 452 92.8 1.3e-18
NP_005347 (OMIM: 153390,615758) tyrosine-protein k ( 509) 452 92.8 1.3e-18
NP_001317394 (OMIM: 191305,613375) tyrosine-protei ( 434) 450 92.4 1.5e-18
XP_011542129 (OMIM: 191305,613375) PREDICTED: tyro ( 460) 450 92.4 1.6e-18
XP_011539315 (OMIM: 164940) PREDICTED: tyrosine-pr ( 352) 427 88.1 2.4e-17
XP_011539314 (OMIM: 164940) PREDICTED: tyrosine-pr ( 410) 427 88.1 2.7e-17
NP_005239 (OMIM: 164940) tyrosine-protein kinase F ( 529) 427 88.2 3.3e-17
XP_011539312 (OMIM: 164940) PREDICTED: tyrosine-pr ( 529) 427 88.2 3.3e-17
NP_001036194 (OMIM: 164940) tyrosine-protein kinas ( 529) 427 88.2 3.3e-17
NP_001036212 (OMIM: 164940) tyrosine-protein kinas ( 529) 427 88.2 3.3e-17
XP_006710515 (OMIM: 164940) PREDICTED: tyrosine-pr ( 529) 427 88.2 3.3e-17
XP_016866144 (OMIM: 137025) PREDICTED: tyrosine-pr ( 311) 421 86.9 4.7e-17
XP_016866139 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17
NP_002028 (OMIM: 137025) tyrosine-protein kinase F ( 537) 421 87.1 7e-17
XP_016866141 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17
XP_016866143 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17
XP_016866142 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17
XP_016866140 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 421 87.1 7e-17
NP_694592 (OMIM: 137025) tyrosine-protein kinase F ( 534) 406 84.4 4.7e-16
XP_005266947 (OMIM: 137025) PREDICTED: tyrosine-pr ( 534) 406 84.4 4.7e-16
XP_005258196 (OMIM: 164880) PREDICTED: tyrosine-pr ( 499) 405 84.2 5.1e-16
NP_005424 (OMIM: 164880) tyrosine-protein kinase Y ( 543) 405 84.2 5.4e-16
XP_016881449 (OMIM: 164880) PREDICTED: tyrosine-pr ( 543) 405 84.2 5.4e-16
NP_001317397 (OMIM: 153390,615758) tyrosine-protei ( 458) 401 83.4 7.9e-16
XP_011539756 (OMIM: 153390,615758) PREDICTED: tyro ( 516) 401 83.5 8.6e-16
XP_011539755 (OMIM: 153390,615758) PREDICTED: tyro ( 516) 401 83.5 8.6e-16
XP_016869228 (OMIM: 601099) PREDICTED: src-like-ad ( 168) 366 76.7 3.1e-14
NP_001269894 (OMIM: 601099) src-like-adapter isofo ( 168) 366 76.7 3.1e-14
>>NP_115590 (OMIM: 606577) src-like-adapter 2 isoform a (261 aa)
initn: 1739 init1: 1739 opt: 1739 Z-score: 1729.8 bits: 327.7 E(85289): 1.3e-89
Smith-Waterman score: 1739; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)
10 20 30 40 50 60
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 DDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEG
190 200 210 220 230 240
250 260
pF1KB7 LRESLSFYISLNDEAVSLDDA
:::::::::::::::::::::
NP_115 LRESLSFYISLNDEAVSLDDA
250 260
>>NP_778252 (OMIM: 606577) src-like-adapter 2 isoform b (210 aa)
initn: 1220 init1: 1193 opt: 1204 Z-score: 1202.7 bits: 229.9 E(85289): 3e-60
Smith-Waterman score: 1204; 89.4% identity (90.8% similar) in 207 aa overlap (1-200:1-207)
10 20 30 40 50 60
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI
70 80 90 100 110 120
130 140 150 160 170
pF1KB7 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSEL-
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSEGW
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 ------ADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGE
: .. :.::: ::
NP_778 PAPWQGYTPTCDCAEDTTQLERAGQLPPVF
190 200 210
>>XP_016883587 (OMIM: 606577) PREDICTED: src-like-adapte (288 aa)
initn: 1213 init1: 1189 opt: 1189 Z-score: 1186.1 bits: 227.2 E(85289): 2.5e-59
Smith-Waterman score: 1189; 99.4% identity (100.0% similar) in 178 aa overlap (1-178:1-178)
10 20 30 40 50 60
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSDRQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 DDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEG
XP_016 KSGLPYFHASPYAKKCRLGALSSPRALAEKPQTSCVGSGQYLAYHSGSDSEPLAAGRVLS
190 200 210 220 230 240
>>NP_001039022 (OMIM: 601099) src-like-adapter isoform b (293 aa)
initn: 631 init1: 334 opt: 644 Z-score: 647.8 bits: 127.7 E(85289): 2.4e-29
Smith-Waterman score: 644; 41.8% identity (67.8% similar) in 261 aa overlap (5-259:12-265)
10 20 30 40 50
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTM-EAERSKATAVALGSFPAGGPAELS
:...: . . :. . .. :. :. : :: :...:. .
NP_001 MLHRLWASPAAPGKKKEMGNSMKSTPAPAERPLPNPEGLDSDFLAV-LSDYPSPDISPPI
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 LRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPG
.: :: : ..:..: :: ..: .::: ::.. ::.: ::::.:::.:.:::::: ::
NP_001 FRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 NPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQAL
. :.:.::::.:..: :::::: . ..:::: : :.: :::::::: :. :
NP_001 TKVGSFMIRESETKKGFYSLSVRHRQ------VKHYRIFRLPNNWYYISPRLTFQCLEDL
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 VDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKE---LDSSLLFSEA
:.::::.:: .::.: ::. : .. . :::... ..:.. :. . .:
NP_001 VNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTEN
180 190 200 210 220 230
230 240 250 260
pF1KB7 ATG-EESLLSEGLRESLSFYISLNDE-AVSLDDA
: .:::.: :::::.. :.::..: .:.:
NP_001 PLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED
240 250 260 270 280 290
>>NP_006739 (OMIM: 601099) src-like-adapter isoform c [H (316 aa)
initn: 650 init1: 334 opt: 644 Z-score: 647.3 bits: 127.7 E(85289): 2.6e-29
Smith-Waterman score: 644; 41.8% identity (67.8% similar) in 261 aa overlap (5-259:35-288)
10 20 30
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTM-EAERS
:...: . . :. . .. :. :. :
NP_006 LGHSPLGGLRARLTFPVCLLYHRLWASPAAPGKKKEMGNSMKSTPAPAERPLPNPEGLDS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 KATAVALGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHG
:: :...:. . .: :: : ..:..: :: ..: .::: ::.. ::.: ::
NP_006 DFLAV-LSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB7 WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCL
::.:::.:.:::::: :: . :.:.::::.:..: :::::: . ..:::: :
NP_006 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQ------VKHYRIFRL
130 140 150 160 170
160 170 180 190 200 210
pF1KB7 DNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRT
:.: :::::::: :. ::.::::.:: .::.: ::. : .. . :::...
NP_006 PNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQK
180 190 200 210 220 230
220 230 240 250 260
pF1KB7 PLNWKE---LDSSLLFSEAATG-EESLLSEGLRESLSFYISLNDE-AVSLDDA
..:.. :. . .: : .:::.: :::::.. :.::..: .:.:
NP_006 TVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLM
240 250 260 270 280 290
NP_006 YGGSKRKSSFFSSPPYFED
300 310
>>NP_001039021 (OMIM: 601099) src-like-adapter isoform a (276 aa)
initn: 651 init1: 334 opt: 630 Z-score: 634.3 bits: 125.1 E(85289): 1.4e-28
Smith-Waterman score: 630; 42.8% identity (66.9% similar) in 257 aa overlap (9-259:6-248)
10 20 30 40 50
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTM-EAERSKATAVALGSFPAGGPAELSLRLGEPL
:: :.:. . :. :. : :: :...:. . .: :: :
NP_001 MGNSMKSTPAPA-------ERPLPNPEGLDSDFLAV-LSDYPSPDISPPIFRRGEKL
10 20 30 40
60 70 80 90 100 110
pF1KB7 TIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFL
..:..: :: ..: .::: ::.. ::.: ::::.:::.:.:::::: :: . :.:.
NP_001 RVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFM
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 IRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSEL
::::.:..: :::::: . ..:::: : :.: :::::::: :. ::.::::.
NP_001 IRESETKKGFYSLSVRHRQ------VKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 ADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKE---LDSSLLFSEAATG-EES
:: .::.: ::. : .. . :::... ..:.. :. . .: : .::
NP_001 ADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDES
170 180 190 200 210 220
240 250 260
pF1KB7 LLSEGLRESLSFYISLNDE-AVSLDDA
:.: :::::.. :.::..: .:.:
NP_001 LFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED
230 240 250 260 270
>>XP_016868905 (OMIM: 165120) PREDICTED: tyrosine-protei (491 aa)
initn: 485 init1: 356 opt: 493 Z-score: 495.6 bits: 100.3 E(85289): 7.2e-21
Smith-Waterman score: 493; 40.9% identity (66.7% similar) in 198 aa overlap (9-202:20-212)
10 20 30 40
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPA
:. : : :. . :: : . :.. .::: . . :
XP_016 MGCIKSKGKDSLSDDGVDLKTQPVPE-SQLLPGQRFQTKDPEEQGDIVVALYPYDGIHPD
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 ELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKV----SHGWLYEGLSREKAE
.::.. :: . .. : :.:: . : .. .: ::: .:::. .. :... ..:. ::
XP_016 DLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 ELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLT
. :: ::: .::::::::.: .::.::::: :. : :.::.:. :::: :::::.:
XP_016 RQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRIT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 FPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLL
:: .. .. ::.. :: .: :.. :. .: : :
XP_016 FPCISDMIKHYQKQADGLCRRLEKACI----SPKPQKPWDKDAWEIPRESIKLVKRLGAG
180 190 200 210 220 230
230 240 250 260
pF1KB7 FSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA
XP_016 QFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIY
240 250 260 270 280 290
>>NP_001104567 (OMIM: 165120) tyrosine-protein kinase Ly (491 aa)
initn: 485 init1: 356 opt: 493 Z-score: 495.6 bits: 100.3 E(85289): 7.2e-21
Smith-Waterman score: 493; 40.9% identity (66.7% similar) in 198 aa overlap (9-202:20-212)
10 20 30 40
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPA
:. : : :. . :: : . :.. .::: . . :
NP_001 MGCIKSKGKDSLSDDGVDLKTQPVPE-SQLLPGQRFQTKDPEEQGDIVVALYPYDGIHPD
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 ELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKV----SHGWLYEGLSREKAE
.::.. :: . .. : :.:: . : .. .: ::: .:::. .. :... ..:. ::
NP_001 DLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 ELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLT
. :: ::: .::::::::.: .::.::::: :. : :.::.:. :::: :::::.:
NP_001 RQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRIT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 FPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLL
:: .. .. ::.. :: .: :.. :. .: : :
NP_001 FPCISDMIKHYQKQADGLCRRLEKACI----SPKPQKPWDKDAWEIPRESIKLVKRLGAG
180 190 200 210 220 230
230 240 250 260
pF1KB7 FSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA
NP_001 QFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIY
240 250 260 270 280 290
>>NP_002341 (OMIM: 165120) tyrosine-protein kinase Lyn i (512 aa)
initn: 485 init1: 356 opt: 493 Z-score: 495.4 bits: 100.3 E(85289): 7.4e-21
Smith-Waterman score: 493; 40.3% identity (66.7% similar) in 201 aa overlap (6-202:38-233)
10 20 30
pF1KB7 MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKA
: ... : : :. . :: : . :..
NP_002 GKDSLSDDGVDLKTQPVRNTERTIYVRDPTSNKQQRPVPE-SQLLPGQRFQTKDPEEQGD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 TAVALGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKV----S
.::: . . : .::.. :: . .. : :.:: . : .. .: ::: .:::. .
NP_002 IVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLET
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB7 HGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIH
. :... ..:. ::. :: ::: .::::::::.: .::.::::: :. : :.::.:.
NP_002 EEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB7 CLDNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQ
:::: :::::.::: .. .. ::.. :: .: :.. :. .: : :
NP_002 SLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACI----SPKPQKPWDKDAWEI
190 200 210 220 230 240
220 230 240 250 260
pF1KB7 RTPLNWKELDSSLLFSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA
NP_002 PRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKL
250 260 270 280 290 300
>>XP_016868904 (OMIM: 165120) PREDICTED: tyrosine-protei (499 aa)
initn: 485 init1: 356 opt: 490 Z-score: 492.6 bits: 99.7 E(85289): 1.1e-20
Smith-Waterman score: 490; 39.9% identity (65.4% similar) in 208 aa overlap (2-202:203-403)
10 20
pF1KB7 MGSLPSR---RKSLPSPSLSSSVQGQGPVTM
:. : : :. .: .: . :: :
XP_016 ASSVPGQQPPHTQVLLGRPVAPPTLNSSHRGAPPPRNFHRERVPESQL---LPGQRFQTK
180 190 200 210 220
30 40 50 60 70 80
pF1KB7 EAERSKATAVALGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVA
. :.. .::: . . : .::.. :: . .. : :.:: . : .. .: ::: .::
XP_016 DPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVA
230 240 250 260 270 280
90 100 110 120 130 140
pF1KB7 KV----SHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDR
:. .. :... ..:. ::. :: ::: .::::::::.: .::.::::: :. :
XP_016 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV
290 300 310 320 330 340
150 160 170 180 190 200
pF1KB7 IRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDI
:.::.:. :::: :::::.::: .. .. ::.. :: .: :.. :. .: : :
XP_016 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACI----SPKPQKPW
350 360 370 380 390 400
210 220 230 240 250 260
pF1KB7 PLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA
XP_016 DKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMK
410 420 430 440 450 460
261 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:44:54 2016 done: Sat Nov 5 14:44:55 2016
Total Scan time: 6.600 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]