FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7961, 265 aa 1>>>pF1KB7961 265 - 265 aa - 265 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6643+/-0.000908; mu= 12.8457+/- 0.054 mean_var=67.5294+/-13.751, 0's: 0 Z-trim(105.9): 72 B-trim: 135 in 1/47 Lambda= 0.156073 statistics sampled from 8592 (8666) to 8592 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.266), width: 16 Scan time: 2.190 The best scores are: opt bits E(32554) CCDS7892.1 ELF5 gene_id:2001|Hs108|chr11 ( 265) 1872 430.3 6.5e-121 CCDS7893.1 ELF5 gene_id:2001|Hs108|chr11 ( 255) 1798 413.7 6.5e-116 CCDS73273.1 ELF5 gene_id:2001|Hs108|chr11 ( 187) 932 218.6 2.5e-57 CCDS58129.1 ELF5 gene_id:2001|Hs108|chr11 ( 160) 820 193.4 8.4e-50 CCDS55753.1 EHF gene_id:26298|Hs108|chr11 ( 277) 479 116.7 1.8e-26 CCDS7894.1 EHF gene_id:26298|Hs108|chr11 ( 300) 479 116.7 1.9e-26 CCDS55752.1 EHF gene_id:26298|Hs108|chr11 ( 322) 479 116.7 2e-26 CCDS1419.1 ELF3 gene_id:1999|Hs108|chr1 ( 371) 465 113.6 2e-25 CCDS4794.1 SPDEF gene_id:25803|Hs108|chr6 ( 335) 331 83.4 2.3e-16 CCDS64063.1 ELF2 gene_id:1998|Hs108|chr4 ( 504) 286 73.3 3.6e-13 CCDS59013.1 SPDEF gene_id:25803|Hs108|chr6 ( 319) 283 72.6 3.9e-13 CCDS64062.1 ELF2 gene_id:1998|Hs108|chr4 ( 521) 277 71.3 1.5e-12 CCDS3745.1 ELF2 gene_id:1998|Hs108|chr4 ( 533) 277 71.3 1.6e-12 CCDS3744.1 ELF2 gene_id:1998|Hs108|chr4 ( 581) 277 71.3 1.7e-12 CCDS82954.1 ELF2 gene_id:1998|Hs108|chr4 ( 593) 277 71.3 1.7e-12 CCDS14617.1 ELF4 gene_id:2000|Hs108|chrX ( 663) 262 68.0 2e-11 CCDS45043.1 ELF1 gene_id:1997|Hs108|chr13 ( 595) 259 67.3 2.9e-11 CCDS9374.1 ELF1 gene_id:1997|Hs108|chr13 ( 619) 259 67.3 3e-11 >>CCDS7892.1 ELF5 gene_id:2001|Hs108|chr11 (265 aa) initn: 1872 init1: 1872 opt: 1872 Z-score: 2284.3 bits: 430.3 E(32554): 6.5e-121 Smith-Waterman score: 1872; 100.0% identity (100.0% similar) in 265 aa overlap (1-265:1-265) 10 20 30 40 50 60 pF1KB7 MPSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 MPSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 PEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 ILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 DLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTG 190 200 210 220 230 240 250 260 pF1KB7 ILERVDRRLVYKFGKNAHGWQEDKL ::::::::::::::::::::::::: CCDS78 ILERVDRRLVYKFGKNAHGWQEDKL 250 260 >>CCDS7893.1 ELF5 gene_id:2001|Hs108|chr11 (255 aa) initn: 1798 init1: 1798 opt: 1798 Z-score: 2194.5 bits: 413.7 E(32554): 6.5e-116 Smith-Waterman score: 1798; 100.0% identity (100.0% similar) in 255 aa overlap (11-265:1-255) 10 20 30 40 50 60 pF1KB7 MPSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVH :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 MLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVH 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 PEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 PEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 ILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 ILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVR 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 DLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 DLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTG 180 190 200 210 220 230 250 260 pF1KB7 ILERVDRRLVYKFGKNAHGWQEDKL ::::::::::::::::::::::::: CCDS78 ILERVDRRLVYKFGKNAHGWQEDKL 240 250 >>CCDS73273.1 ELF5 gene_id:2001|Hs108|chr11 (187 aa) initn: 1275 init1: 932 opt: 932 Z-score: 1142.8 bits: 218.6 E(32554): 2.5e-57 Smith-Waterman score: 1123; 70.6% identity (70.6% similar) in 265 aa overlap (1-265:1-187) 10 20 30 40 50 60 pF1KB7 MPSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVH :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MPSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQT---------- 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 PEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYF CCDS73 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB7 ILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVR :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 --------GYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVR 60 70 80 90 100 190 200 210 220 230 240 pF1KB7 DLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 DLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTG 110 120 130 140 150 160 250 260 pF1KB7 ILERVDRRLVYKFGKNAHGWQEDKL ::::::::::::::::::::::::: CCDS73 ILERVDRRLVYKFGKNAHGWQEDKL 170 180 >>CCDS58129.1 ELF5 gene_id:2001|Hs108|chr11 (160 aa) initn: 815 init1: 815 opt: 820 Z-score: 1007.6 bits: 193.4 E(32554): 8.4e-50 Smith-Waterman score: 896; 62.7% identity (62.7% similar) in 255 aa overlap (11-265:1-160) 10 20 30 40 50 60 pF1KB7 MPSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVH :::::::::::::::::::::::::::::::::::::::: CCDS58 MLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQT---------- 10 20 30 40 70 80 90 100 110 120 pF1KB7 PEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYF CCDS58 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB7 ILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVR :: ::::::::::::::::::::::::::::::::: CCDS58 --------------DA-----------DSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVR 50 60 70 190 200 210 220 230 240 pF1KB7 DLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTG 80 90 100 110 120 130 250 260 pF1KB7 ILERVDRRLVYKFGKNAHGWQEDKL ::::::::::::::::::::::::: CCDS58 ILERVDRRLVYKFGKNAHGWQEDKL 140 150 160 >>CCDS55753.1 EHF gene_id:26298|Hs108|chr11 (277 aa) initn: 764 init1: 372 opt: 479 Z-score: 588.8 bits: 116.7 E(32554): 1.8e-26 Smith-Waterman score: 738; 44.6% identity (70.8% similar) in 260 aa overlap (32-264:23-276) 10 20 30 40 50 60 pF1KB7 PSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHP .::: .:. . .: . : .:: CCDS55 MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGF-----FGGQWHEIHP 10 20 30 40 70 80 90 100 110 120 pF1KB7 EYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFI .:::: .:::::: : .::.::: : .:.:.: .::::. .::..::: :. :: CCDS55 QYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSN 50 60 70 80 90 100 130 140 150 pF1KB7 LQNIRTQGY---SFFNDA-------EESKATIKD-YADSNCLKTSGI-----------KS ::... .: ..:... :... .: . . : : : .. : CCDS55 LQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVAESPDMKKE 110 120 130 140 150 160 160 170 180 190 200 210 pF1KB7 QD----CHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMW :: ::..... ...:::::.::.::.:..: :...:::: .:.:: .::::.:..: CCDS55 QDPPAKCHTKKHNP-RGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLW 170 180 190 200 210 220 220 230 240 250 260 pF1KB7 GQRKKNDRMTYEKLSRALRYYYKTGILERVD-RRLVYKFGKNAHGWQEDKL :..:.:. :::::::::.::::: :::::: :::::::::::.::.:.. CCDS55 GKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN 230 240 250 260 270 >>CCDS7894.1 EHF gene_id:26298|Hs108|chr11 (300 aa) initn: 748 init1: 372 opt: 479 Z-score: 588.3 bits: 116.7 E(32554): 1.9e-26 Smith-Waterman score: 696; 42.4% identity (65.7% similar) in 283 aa overlap (32-264:23-299) 10 20 30 40 50 60 pF1KB7 PSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHP .::: .:. . .: . : .:: CCDS78 MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGF-----FGGQWHEIHP 10 20 30 40 70 80 90 100 110 120 pF1KB7 EYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFI .:::: .:::::: : .::.::: : .:.:.: .::::. .::..::: :. :: CCDS78 QYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSN 50 60 70 80 90 100 130 140 150 pF1KB7 LQNIRTQGY---SFFNDA-------EESKATI----KDYA---DSN-------------C ::... .: ..:... :... .: :: :.: : CCDS78 LQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTFC 110 120 130 140 150 160 160 170 180 190 pF1KB7 ------LKTSGI---------KSQD----CHSHSRTSLQSSHLWEFVRDLLLSPEENCGI :: . : :: ::..... ...:::::.::.::.:..: :. CCDS78 RAQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNP-RGTHLWEFIRDILLNPDKNPGL 170 180 190 200 210 220 200 210 220 230 240 250 pF1KB7 LEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD-RRLVY ..:::: .:.:: .::::.:..::..:.:. :::::::::.::::: :::::: ::::: CCDS78 IKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVY 230 240 250 260 270 280 260 pF1KB7 KFGKNAHGWQEDKL ::::::.::.:.. CCDS78 KFGKNARGWRENEN 290 300 >>CCDS55752.1 EHF gene_id:26298|Hs108|chr11 (322 aa) initn: 748 init1: 372 opt: 479 Z-score: 587.8 bits: 116.7 E(32554): 2e-26 Smith-Waterman score: 696; 42.4% identity (65.7% similar) in 283 aa overlap (32-264:45-321) 10 20 30 40 50 60 pF1KB7 PSLPHSHRVMLDSVTHSTFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHP .::: .:. . .: . : .:: CCDS55 LAEILFKIMILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGF-----FGGQWHEIHP 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFI .:::: .:::::: : .::.::: : .:.:.: .::::. .::..::: :. :: CCDS55 QYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSN 70 80 90 100 110 120 130 140 150 pF1KB7 LQNIRTQGY---SFFNDA-------EESKATI----KDYA---DSN-------------C ::... .: ..:... :... .: :: :.: : CCDS55 LQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTFC 130 140 150 160 170 180 160 170 180 190 pF1KB7 ------LKTSGI---------KSQD----CHSHSRTSLQSSHLWEFVRDLLLSPEENCGI :: . : :: ::..... ...:::::.::.::.:..: :. CCDS55 RAQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNP-RGTHLWEFIRDILLNPDKNPGL 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB7 LEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD-RRLVY ..:::: .:.:: .::::.:..::..:.:. :::::::::.::::: :::::: ::::: CCDS55 IKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVY 250 260 270 280 290 300 260 pF1KB7 KFGKNAHGWQEDKL ::::::.::.:.. CCDS55 KFGKNARGWRENEN 310 320 >>CCDS1419.1 ELF3 gene_id:1999|Hs108|chr1 (371 aa) initn: 481 init1: 368 opt: 465 Z-score: 569.8 bits: 113.6 E(32554): 2e-25 Smith-Waterman score: 465; 58.3% identity (87.0% similar) in 108 aa overlap (161-265:259-366) 140 150 160 170 180 pF1KB7 SFFNDAEESKATIKDYADSNCLKTSGIKSQDC--HSHSRTSLQSSHLWEFVRDLLLSPEE :: ..:. . ...:::::.::.:. :: CCDS14 SDGFRDCKKGDPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPEL 230 240 250 260 270 280 190 200 210 220 230 240 pF1KB7 NCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD-R : :...::.:..:.:. ..:::.:..:::.:::. :::::::::.::::: :::::: : CCDS14 NEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGR 290 300 310 320 330 340 250 260 pF1KB7 RLVYKFGKNAHGWQEDKL :::::::::. ::.:... CCDS14 RLVYKFGKNSSGWKEEEVLQSRN 350 360 370 >>CCDS4794.1 SPDEF gene_id:25803|Hs108|chr6 (335 aa) initn: 324 init1: 261 opt: 331 Z-score: 407.4 bits: 83.4 E(32554): 2.3e-16 Smith-Waterman score: 392; 33.3% identity (60.9% similar) in 207 aa overlap (49-253:135-331) 20 30 40 50 60 70 pF1KB7 TFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCD .::: .. : :. .: .:: . CCDS47 LDLVPGGLTLEEHSLEQVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEH 110 120 130 140 150 160 80 90 100 110 120 130 pF1KB7 QYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFILQNIRTQGYSFFNDAEE ::.: .: ...: .::.:..:.: . . : :. :. :. ....: CCDS47 QYRLPPMGKAFQ--ELAGKELCAMSEEQFRQRSPLGGDVLHAHLD--------IWKSAAW 170 180 190 200 210 140 150 160 170 180 190 pF1KB7 SKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDR : . : : .:: . : . : : : :::.:...:::.:. ...: .. CCDS47 MKERTSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNK 220 230 240 250 260 270 200 210 220 230 240 250 pF1KB7 EQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD--RRLVYKFGKN :.:::.. : .:..:: ::. :.:.::::..: ::: ::... : .::::.: CCDS47 EKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHP 280 290 300 310 320 330 260 pF1KB7 AHGWQEDKL CCDS47 I >>CCDS64063.1 ELF2 gene_id:1998|Hs108|chr4 (504 aa) initn: 274 init1: 246 opt: 286 Z-score: 349.8 bits: 73.3 E(32554): 3.6e-13 Smith-Waterman score: 286; 42.7% identity (76.4% similar) in 110 aa overlap (148-253:92-200) 120 130 140 150 160 170 pF1KB7 LYFILQNIRTQGYSFFNDAEESKATIKDYADSNCLKTSGIK-SQDCHS-HSRTSLQSSHL .:. . :: : : : : .. . ....: CCDS64 VPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKGNTTYL 70 80 90 100 110 120 180 190 200 210 220 230 pF1KB7 WEFVRDLLLSPEENCG-ILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALR :::. ::: . ...: ..: .::.:::..: :.:..:.::..:.. :.:: ..:::: CCDS64 WEFLLDLL-QDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALR 130 140 150 160 170 180 240 250 260 pF1KB7 YYYKTGILERVD-RRLVYKFGKNAHGWQEDKL :::. ::: .:. .::::.: CCDS64 YYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCNEDLAGTTDEKSLERVSLSAES 190 200 210 220 230 240 265 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:17:02 2016 done: Sat Nov 5 10:17:02 2016 Total Scan time: 2.190 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]